LOCUS       NM_144890               1637 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus BPI fold containing family B, member 5 (Bpifb5), mRNA.
ACCESSION   NM_144890 XM_919659
VERSION     NM_144890.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1637)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1637)
  AUTHORS   Jones,M.R., Dilai,S., Lingampally,A., Chao,C.M., Danopoulos,S.,
            Carraro,G., Mukhametshina,R., Wilhelm,J., Baumgart-Vogt,E., Al
            Alam,D., Chen,C., Minoo,P., Zhang,J.S. and Bellusci,S.
  TITLE     A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b
            Signaling on Epithelial Tip Progenitor Cells During Early Mouse
            Lung Branching Morphogenesis
  JOURNAL   Front Genet 9, 746 (2019)
   PUBMED   30728831
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1637)
  AUTHORS   Bingle,C.D., Seal,R.L. and Craven,C.J.
  TITLE     Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a
            subfamily of the BPI fold-containing superfamily
  JOURNAL   Biochem Soc Trans 39 (4), 977-983 (2011)
   PUBMED   21787333
REFERENCE   5  (bases 1 to 1637)
  AUTHORS   Wheeler,T.T., Hood,K.A., Maqbool,N.J., McEwan,J.C., Bingle,C.D. and
            Zhao,S.
  TITLE     Expansion of the Bactericidal/Permeability Increasing-like
            (BPI-like) protein locus in cattle
  JOURNAL   BMC Genomics 8, 75 (2007)
   PUBMED   17362520
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1637)
  AUTHORS   Bingle,C.D., LeClair,E.E., Havard,S., Bingle,L., Gillingham,P. and
            Craven,C.J.
  TITLE     Phylogenetic and evolutionary analysis of the PLUNC gene family
  JOURNAL   Protein Sci 13 (2), 422-430 (2004)
   PUBMED   14739326
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK142982.1 and AL732601.16.
            
            On Jul 24, 2009 this sequence version replaced NM_144890.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK142982.1, BC018465.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1635              AK142982.1         2-1636
            1636-1637           AL732601.16        61536-61537
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 76.28 cM"
     gene            1..1637
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /note="BPI fold containing family B, member 5"
                     /db_xref="GeneID:228802"
                     /db_xref="MGI:MGI:2385160"
     exon            1..152
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..1516
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /note="long palate lung and nasal epithelium protein 5"
                     /codon_start=1
                     /product="long palate lung and nasal epithelium protein 5
                     precursor"
                     /protein_id="NP_659139.2"
                     /db_xref="CCDS:CCDS16928.1"
                     /db_xref="GeneID:228802"
                     /db_xref="MGI:MGI:2385160"
                     /translation="MLLLWALLLCWGVLPQARGATHTHLFLRINNSQLETDISNLLSE
                     NQVLEGMIRMAVTGSPSEGVSVMDSLPFVREELVDKKSGLDLSLVGDLLSGKTMPELK
                     KLLTTAGLVIEDAKGPEVTLQILSDSLLQITLRCKLYLSFLEILWLEAIKNIRIGVRL
                     EQIGNKTQVAFEECHTPPGSLNIKILKRSDTLLPNQLLKLVTNTLEKSLPFLLQKIVC
                     PVATNLINFLLEDILHIILPPIISGPDDFQYYVTTTEFTEGAILMRVALVTPCGPHQR
                     APRSEHMVPPPLPGLSQNSMADLAFWLEIYNDILACLYTSQEISVEPQDSSETDLWEL
                     LSLSSPQSQPKAYNLTRGSLGLIISAPNPPTVLLDGRRTTVTQQGLLMLHGTNASSDA
                     VAWQLLCRGEFSLRSQKQQLQFAPHGAVVTLGPYPTIIKEQEERLKTLLLAVLKRWFL
                     PHHNEWLREHSLPLPNIKGVSFSLAQMDFSEDYILLTVPE"
     exon            153..369
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            370..474
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            475..606
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            607..691
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            692..755
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            756..841
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            842..1024
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1078
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1228
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1296
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1342
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1406
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1486
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1637
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1618..1623
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /note="hexamer: AATAAA"
     polyA_site      1637
                     /gene="Bpifb5"
                     /gene_synonym="Lplunc5"
                     /note="major polyA site"
ORIGIN      
        1 tctcactccc ctggccagcc ggggcgcagg ctctgaagca gggatgctgc tgctgtgggc
       61 actgctgtta tgctgggggg tgctgcccca agcccgaggg gcaacccaca ctcatctctt
      121 cctgcggatc aacaatagcc agctggaaac agacatctca aatctattat cagagaacca
      181 ggtcctggag ggtatgatca ggatggctgt gactggatcc ccaagtgagg gtgtgtctgt
      241 catggactcc ctgcccttcg tcagagagga gctcgttgac aagaagagtg ggctggatct
      301 gtcattggtg ggggacctgc tctctgggaa gactatgcct gagctgaaga aactgctgac
      361 gacagccggg ttggtcatag aagatgccaa gggaccagaa gtcaccctgc aaattctaag
      421 tgacagcctg ctgcagatca cactgcgctg caagctgtac ctctcattcc tagagatcct
      481 ctggctggaa gccatcaaga acatacgaat tggagtacgg ctagaacaga tagggaacaa
      541 gacccaggtg gccttcgagg agtgccacac accacctgga agcctgaaca tcaagatcct
      601 gaagcgatca gacaccctgt tgccaaacca actgctgaaa ctggtgacca acaccctgga
      661 gaaatccctg cctttcctcc tccagaagat agtgtgccct gtggccacaa acctgatcaa
      721 cttcctgctg gaagacatac tacacatcat tcttcctccc atcatctctg gtcccgatga
      781 tttccagtac tacgtgacca ccacagagtt cacagaggga gccatcctga tgcgagtggc
      841 gcttgtgact ccctgtggcc cacaccagcg ggcaccaagg tcagaacaca tggttccccc
      901 acctctccca ggattatccc agaacagcat ggcagatctt gccttttggc tagaaatcta
      961 caatgacatc ctggcctgtc tctacaccag ccaggagatc tctgtggagc cccaggactc
     1021 ctcggaaact gacctctggg agctgttgtc cctgagcagc ccgcagtccc aacccaaggc
     1081 ttataatctg acccgaggga gcctgggcct gatcatcagc gccccaaacc cccccaccgt
     1141 cctccttgat ggccgcagga ccacggtcac ccagcagggc ttactgatgc tgcatgggac
     1201 caatgcctcc tctgatgcag ttgcctggca actcctctgc agaggcgagt tctccttaag
     1261 gagtcagaaa cagcaactcc agttcgcacc acacggcgct gtggtcacct tgggccccta
     1321 ccccactatc attaaggagc aggaagagcg cctgaagacc ttgctcttgg ctgtcctgaa
     1381 gaggtggttc ctgcctcacc acaatgagtg gctcagagag catagcctcc cactgcccaa
     1441 catcaagggc gtctccttca gccttgccca aatggacttc tctgaggatt acatcctgct
     1501 gaccgttccg gagtagctgc tctgctgggg ccctgtccct gtccctgccc acagctgcac
     1561 atggtcaaga gctcaaagcc caagatcagc ggcggtctca gtggagtccg cagctagaat
     1621 aaagatgttt cctctaa
//
