LOCUS       NM_175265               2659 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus bora, aurora kinase A activator (Bora), transcript
            variant 1, mRNA.
ACCESSION   NM_175265
VERSION     NM_175265.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2659)
  AUTHORS   Zhai,R., Yuan,Y.F., Zhao,Y., Liu,X.M., Zhen,Y.H., Yang,F.F.,
            Wang,L., Huang,C.Z., Cao,J. and Huo,L.J.
  TITLE     Bora regulates meiotic spindle assembly and cell cycle during mouse
            oocyte meiosis
  JOURNAL   Mol Reprod Dev 80 (6), 474-487 (2013)
   PUBMED   23610072
  REMARK    GeneRIF: Studied the expression, localization, and function of Bora
            during mouse oocyte meiosis. Findings indicated that Bora acts as a
            critical regulator of Aurora A and Plk1, and is involved in
            microtubule organization during oocyte meiosis.
REFERENCE   2  (bases 1 to 2659)
  AUTHORS   Hutterer,A., Berdnik,D., Wirtz-Peitz,F., Zigman,M., Schleiffer,A.
            and Knoblich,J.A.
  TITLE     Mitotic activation of the kinase Aurora-A requires its binding
            partner Bora
  JOURNAL   Dev Cell 11 (2), 147-157 (2006)
   PUBMED   16890155
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154843.2.
            
            On Jan 24, 2023 this sequence version replaced NM_175265.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK167430.1, AK141389.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-237               AC154843.2         58413-58649
            238-405             AC154843.2         59270-59437
            406-512             AC154843.2         61962-62068
            513-558             AC154843.2         65487-65532
            559-640             AC154843.2         68708-68789
            641-706             AC154843.2         72209-72274
            707-763             AC154843.2         72944-73000
            764-927             AC154843.2         73489-73652
            928-1063            AC154843.2         74238-74373
            1064-1617           AC154843.2         79977-80530
            1618-1764           AC154843.2         84571-84717
            1765-2659           AC154843.2         85615-86509
FEATURES             Location/Qualifiers
     source          1..2659
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 49.23 cM"
     gene            1..2659
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /note="bora, aurora kinase A activator"
                     /db_xref="GeneID:77744"
                     /db_xref="MGI:MGI:1924994"
     exon            1..237
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            238..405
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             253..1830
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /note="aurora borealis"
                     /codon_start=1
                     /product="protein aurora borealis"
                     /protein_id="NP_780474.1"
                     /db_xref="CCDS:CCDS27309.1"
                     /db_xref="GeneID:77744"
                     /db_xref="MGI:MGI:1924994"
                     /translation="MGDVSELKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSI
                     FKSTKLPTPGKFRWSIDQLAIINPVEIDPEEIHRQASYLRLSRIDKDVEDKRQKAIEE
                     FFTKDVIVPSPWTDHDGKQPSELHPSKCLSSHDDSPDGKKPSLPSQKCNAACQTLLSL
                     PVDFNLEAILGDYFREEDFVAHTPGNLSSSSLRRKLFLDGNGSICDPLPSPSPGSPPC
                     SARGSLEGQFSSSPIQNSVKKYSLGSVTTSPSAISSPTFSPIALQGGKTPLSEPRKLT
                     FHSPEASCATASTGIVNPSIRSPYIDGCSPIKNWSPRRLRGGPQCLSSLVRIPFTLEA
                     HSEDEEADVSCTGAAPLSTNACGEPRVVTAMSVTQSHSGIAEKERAVLDDAESEREND
                     TVDMVDPTDTVAESTWIKEPVDDGNSPMTDSASGIAFSIENSHMCMSPLAESSVLPYE
                     SSAIQMNSDYNTQTCVSNITDIVGTERYCKENVTHTNVPVPFEVEMKSQVNNVTPGHT
                     AQRCWMKSPRPSQCSRP"
     exon            406..512
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            513..558
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            559..640
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            641..706
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            707..763
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            764..927
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1063
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1617
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1618..1764
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..2659
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1990..1995
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2015
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
     regulatory      2639..2644
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2659
                     /gene="Bora"
                     /gene_synonym="6720463M24Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcagggtgat gctagaactt ccacgttgcc cacgagtgta ggtacgttct ccgtggcccc
       61 aggcctggac tcctgcttcg aggtggaccg ctctggtttc ctggccccag acgtacctgt
      121 gagctcgcct aggtgtgaag gggagcagag agagagggcg cctggacact gaatggtcgc
      181 tggaagtgac gtctctgctg tttccgaggg agcccgctca actttgatct tacaaaattt
      241 gcttcctggg ctatgggaga tgtcagcgaa ttaaaaatgc aaataacacc agaaactcca
      301 ggaaggatcc ctgttttaaa tccctttgaa agtcccagtg attattctaa tctccatgaa
      361 caaacccttg ctagtccttc tatctttaag tccacaaaac taccaactcc agggaaattt
      421 aggtggtcta ttgatcagct ggccataata aaccctgtag agatcgatcc agaggagatc
      481 catcggcagg cttcctacct aaggctttct cgaatagata aagatgtgga agacaaaaga
      541 caaaaagcca ttgaagagtt ttttactaaa gatgtcattg tgccctctcc ctggactgat
      601 catgatggaa aacagccttc agagcttcat cccagtaaat gcctaagtag ccatgatgac
      661 tctcctgatg ggaaaaagcc aagtcttccc tcacagaagt gcaacgctgc ctgccagact
      721 ctgctgtctc ttcctgtgga ttttaatttg gaagccatat taggagacta ttttagagaa
      781 gaggactttg tggcccacac tcctgggaac ctcagttctt catctctgag aagaaagctc
      841 tttttggatg ggaatggaag catctgtgac cctttgcctt cgccgtcgcc cggaagtcct
      901 ccctgcagtg cccgggggtc gctcgaggga cagttttctt ccagccccat tcagaacagt
      961 gtgaaaaaat acagcttggg aagcgtcacc acgagcccgt cggccatctc ctcacctacc
     1021 ttctcaccta tcgcacttca aggaggaaag acgccgctct cagaacccag gaagcttacg
     1081 tttcattctc ccgaagcttc gtgtgcaaca gcttctacgg ggatcgttaa cccgagcatc
     1141 aggagtccgt acatagatgg ctgctcgcca atcaaaaact ggtctcctcg gagactgaga
     1201 ggtggccctc agtgtttgtc ctccctggtc cgcatacctt ttacccttga ggctcacagt
     1261 gaagatgaag aggcggacgt ttcctgcaca ggcgcggctc cactcagcac aaatgcttgt
     1321 ggtgagcctc gagttgtcac tgccatgtct gttacacaga gtcactctgg tattgctgag
     1381 aaagagcgag cagtgctgga cgatgcggaa agtgagaggg aaaatgacac cgtggatatg
     1441 gtcgatccta cagacacagt agctgaaagc acgtggataa aagagccagt ggatgatggg
     1501 aattcaccca tgacggattc cgcgagtgga attgccttca gtattgaaaa ctctcatatg
     1561 tgcatgtcgc ctcttgcaga aagcagtgtc ctgccttatg aaagcagtgc tatccagatg
     1621 aatagtgact ataacacaca gacttgtgta agtaatatca ctgatattgt tgggacagaa
     1681 agatattgca aagaaaatgt cacacataca aatgttccag tgccctttga agtggaaatg
     1741 aaatctcaag ttaataacgt aacgcccggc cacacagcgc agcggtgctg gatgaaatct
     1801 ccgcgtccat ctcagtgcag ccgcccgtag tctcaagacc aaagacgggt gctcagcgag
     1861 ttagtgtgat gctgatgggt gcctgcttca cgtactgtgc ctacttccct cagtaatgtg
     1921 aaaggctgca aaggaaattg gtgctaggac cagaaactcc aagttgttaa attatgtttt
     1981 ttttaaatca ataaatattt ctatatttgc ttcaagtggc ttgtttaaca agtaaattat
     2041 ggcagacctc atggctttct cctgtcctac agggtcaatg aactgcttgt taagactttg
     2101 aatggtagtc ttgaatttat cagttctagg aacatgagaa aaatgtggaa acggaatgca
     2161 ctatgtattt ttacatgaaa ctgtgtgaaa gaagtcttga aatataaaac ttacagaggt
     2221 aaaaggaagt aaaatggact ccctaaaatt tcatttctgt ggggaaatta cttggttcgt
     2281 ggtataagcg cgctagttaa tactctgaac actataaatg tagaaaggtg ctactgggca
     2341 ccatccaaat gctgccatct gtaggggcga acatgggctg ccacgatagc atgtacctcc
     2401 attcctaggc ttggtgggga gatgaacaga acacagcaga gtcagaatca ctgggagacc
     2461 ggggaatttc tgttgagaac tatgaagaaa caattgggaa aatagctaaa taaaatacat
     2521 ttaaaaacct gtctgtatta gaaaagaggt ggatataata atgtgtttga gaacaaagac
     2581 tgtatttttg tactttctta aaaactacat aactcaaaat gattcattag tcctagaaaa
     2641 taaagattta ctaccgtta
//
