LOCUS       NM_175103                337 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus bolA family member 2 (Bola2), mRNA.
ACCESSION   NM_175103
VERSION     NM_175103.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 337)
  AUTHORS   Giannuzzi,G., Schmidt,P.J., Porcu,E., Willemin,G., Munson,K.M.,
            Nuttle,X., Earl,R., Chrast,J., Hoekzema,K., Risso,D., Mannik,K., De
            Nittis,P., Baratz,E.D., Herault,Y., Gao,X., Philpott,C.C.,
            Bernier,R.A., Kutalik,Z., Fleming,M.D., Eichler,E.E. and Reymond,A.
  CONSRTM   16p11.2 Consortium
  TITLE     The Human-Specific BOLA2 Duplication Modifies Iron Homeostasis and
            Anemia Predisposition in Chromosome 16p11.2 Autism Individuals
  JOURNAL   Am J Hum Genet 105 (5), 947-958 (2019)
   PUBMED   31668704
REFERENCE   3  (bases 1 to 337)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 337)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 337)
  AUTHORS   Kasai,T., Inoue,M., Koshiba,S., Yabuki,T., Aoki,M., Nunokawa,E.,
            Seki,E., Matsuda,T., Matsuda,N., Tomo,Y., Shirouzu,M., Terada,T.,
            Obayashi,N., Hamana,H., Shinya,N., Tatsuguchi,A., Yasuda,S.,
            Yoshida,M., Hirota,H., Matsuo,Y., Tani,K., Suzuki,H., Arakawa,T.,
            Carninci,P., Kawai,J., Hayashizaki,Y., Kigawa,T. and Yokoyama,S.
  TITLE     Solution structure of a BolA-like protein from Mus musculus
  JOURNAL   Protein Sci 13 (2), 545-548 (2004)
   PUBMED   14718656
  REMARK    GeneRIF: NMR structure of BolA2 [BolA2]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK003922.1.
            
            On Apr 5, 2007 this sequence version replaced NM_175103.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK003922.1, AV451683.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-337               AK003922.1         4-340
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.25 cM"
     gene            1..337
                     /gene="Bola2"
                     /gene_synonym="1110025L05Rik; BolA-2"
                     /note="bolA family member 2"
                     /db_xref="GeneID:66162"
                     /db_xref="MGI:MGI:1913412"
     exon            1..100
                     /gene="Bola2"
                     /gene_synonym="1110025L05Rik; BolA-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..298
                     /gene="Bola2"
                     /gene_synonym="1110025L05Rik; BolA-2"
                     /note="bolA-like 2"
                     /codon_start=1
                     /product="bolA-like protein 2"
                     /protein_id="NP_780312.1"
                     /db_xref="CCDS:CCDS40129.1"
                     /db_xref="GeneID:66162"
                     /db_xref="MGI:MGI:1913412"
                     /translation="MELSADYLREKLRQDLEAEHVEVEDTTLNRCATSFRVLVVSAKF
                     EGKPLLQRHRLVNECLAEELPHIHAFEQKTLTPEQWTRQRRE"
     exon            101..198
                     /gene="Bola2"
                     /gene_synonym="1110025L05Rik; BolA-2"
                     /inference="alignment:Splign:2.1.0"
     exon            199..337
                     /gene="Bola2"
                     /gene_synonym="1110025L05Rik; BolA-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      320..325
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bola2"
                     /gene_synonym="1110025L05Rik; BolA-2"
                     /note="hexamer: ATTAAA"
     polyA_site      337
                     /gene="Bola2"
                     /gene_synonym="1110025L05Rik; BolA-2"
                     /note="major polyA site"
ORIGIN      
        1 tttgcacgct gggctgtagc cccgccgggc tgtggttatg gaactcagcg ccgattacct
       61 ccgcgagaag ctgcggcagg acctggaggc agagcatgtg gaggtggagg acacgactct
      121 gaaccgttgc gcgaccagct tccgagtcct ggtggtgtcg gctaagttcg agggaaagcc
      181 actgctccag agacaccggc tggtgaacga gtgcttagcc gaagagctcc cgcacatcca
      241 tgcctttgag cagaaaactc tgaccccaga gcagtggacc cgacagcggc gtgaatgagg
      301 ggcctaggcc tgaacagtca ttaaaattta aacctgg
//
