LOCUS       NM_134253               1788 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus BCL2/adenovirus E1B 19kD interacting protein like
            (Bnipl), transcript variant 1, mRNA.
ACCESSION   NM_134253
VERSION     NM_134253.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1788)
  AUTHORS   Armfield,B.A., Seifert,A.W., Zheng,Z., Merton,E.M., Rock,J.R.,
            Lopez,M.C., Baker,H.V. and Cohn,M.J.
  TITLE     Molecular Characterization of the Genital Organizer: Gene
            Expression Profile of the Mouse Urethral Plate Epithelium
  JOURNAL   J Urol 196 (4), 1295-1302 (2016)
   PUBMED   27173853
REFERENCE   2  (bases 1 to 1788)
  AUTHORS   Sherwood,R.I., Jitianu,C., Cleaver,O., Shaywitz,D.A., Lamenzo,J.O.,
            Chen,A.E., Golub,T.R. and Melton,D.A.
  TITLE     Prospective isolation and global gene expression analysis of
            definitive and visceral endoderm
  JOURNAL   Dev Biol 304 (2), 541-555 (2007)
   PUBMED   17328885
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC140190.3.
            
            On Dec 4, 2009 this sequence version replaced NM_134253.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            CCDS Note: The coding region has been updated to extend the
            N-terminus to one that is more supported by available conservation
            data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC005659.1, SRR1660817.183787.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AC140190.3         137401-137629       c
            230-325             AC140190.3         136603-136698       c
            326-390             AC140190.3         136242-136306       c
            391-615             AC140190.3         135012-135236       c
            616-798             AC140190.3         132086-132268       c
            799-901             AC140190.3         131421-131523       c
            902-1033            AC140190.3         130578-130709       c
            1034-1120           AC140190.3         129434-129520       c
            1121-1219           AC140190.3         129168-129266       c
            1220-1788           AC140190.3         127729-128297       c
FEATURES             Location/Qualifiers
     source          1..1788
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.74 cM"
     gene            1..1788
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /note="BCL2/adenovirus E1B 19kD interacting protein like"
                     /db_xref="GeneID:171388"
                     /db_xref="MGI:MGI:2384749"
     exon            1..229
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1256
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /note="isoform 1 is encoded by transcript variant 1;
                     bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like
                     protein; BNIP-2 similar"
                     /codon_start=1
                     /product="bcl-2/adenovirus E1B 19 kDa-interacting protein
                     2-like protein isoform 1"
                     /protein_id="NP_599014.2"
                     /db_xref="CCDS:CCDS17609.2"
                     /db_xref="GeneID:171388"
                     /db_xref="MGI:MGI:2384749"
                     /translation="MGTRQETGRETLEGGAKEKAGASEPGATMKLGELELREEWQDEE
                     FPRLLPEEPGSPGDPEDPQRGSQAGTPSSLALCGQRPMRKRLSAPEWQLSLTEGTGEN
                     GASPTRSASSSSAGSLDLEVDELETPSDSEQLDSGHEFEWEDDLPRAEGLGASEAAER
                     LGRGCVCDVAGEDGHRWRVFRTGQREQRVDMTIIEPYKKVLSHGGYHGDGLNAVILFA
                     SCYLPRSSIPNYTYIMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQC
                     YRTLDRRLRKNLRALVVVHATWYVKAFLALVRPFISSKFTRKIRFLDSLGELAQLISL
                     EQVHIPEVVRQLDRDLHGSKGT"
     exon            230..325
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            326..390
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            391..615
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            616..798
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            799..901
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            902..1033
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1120
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            1121..1219
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1788
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1488
                     /gene="Bnipl"
                     /gene_synonym="1700128A13Rik; BNIP-S; BNIPL1; BNIPL2;
                     PP73; PP753"
ORIGIN      
        1 gcaaacctgc tccttgggag gggaggtggc aaaacctgtt tgaagatgag gttacctccc
       61 ttccacacct cctgcctcct tagagcaaaa gcagcagctg acacaggaaa gtaaagagtt
      121 tgggggctgg ggccacagcc tcctatcctc ctcaagtccc acaggacaca ggacgacctg
      181 ggaagatggg gaccaggcaa gaaacaggaa gagagacgtt agaaggaggg gctaaggaga
      241 aggcaggagc ctcagaacca ggagcaacca tgaaacttgg agagctggag ctaagagagg
      301 agtggcaaga tgaagagttt cctagattgc ttcctgagga acctggctca cctggagacc
      361 ctgaagaccc tcagagaggc tcacaggcag gcacccccag cagtctggcc ttgtgtggcc
      421 agcgccctat gcggaagcgt ctttccgccc cagaatggca gctgagtctg actgagggaa
      481 caggagaaaa cggagcctct cccacccgct ctgcgtcttc ctcttctgct ggcagcttgg
      541 acctggaggt ggatgagttg gagacaccat cagactctga gcagctggac agcggacatg
      601 agtttgaatg ggaagatgac ttgccccggg cagagggcct gggggccagt gaggcagcag
      661 aaagactggg ccggggatgc gtgtgcgatg tggctggaga agacggtcat cgctggagag
      721 tgtttcgaac aggacaacga gagcagcgag tggacatgac catcattgag ccctataaga
      781 aagtcttatc tcatggaggt taccatggtg atggcctcaa tgctgtcatc ctctttgctt
      841 cctgctatct accccgaagc agcatcccca actacaccta catcatggaa cacttattca
      901 ggtatatggt gggaactttg gagctgctgg tagctgaaaa ctatctgctt gttcacttga
      961 gtggaggcac cagcagggcc caagtgcccc ctctgagctg gatccggcag tgttaccgta
     1021 ccttggacag gaggcttcgg aaaaaccttc gcgccctggt ggtcgtccac gctacgtggt
     1081 atgtgaaggc cttcctggca ctggttcggc ccttcatcag ctccaagttc acacgaaaga
     1141 tccgctttct ggacagcctc ggagagctgg cccagctcat ctcgctagag caagtgcaca
     1201 taccggaagt tgtcagacag ctggaccggg atctgcatgg ctcgaaaggc acctaacaca
     1261 aagctgggca gagggcctag gatctggcaa agatcatgag tggtctgcat gggggagcta
     1321 tgtctcatct catcctgagg gccagctcca ccggatcctc acttttcagt gcgacgccca
     1381 cttctggaca ctgccttcaa gctgggattt aagggtggga accccagaac ggggtggggg
     1441 gtggcttgca tttcggctgt ccaaaaagaa ggctgtgtgg cattggaagt gtaaggctct
     1501 gagttttaat tctgctttag ctgtaaaata tgtgggtctc attttccttc tctgtaatca
     1561 aaactactgg gatccttccc agtttagttg tcttagcagt ctttgagggg aggtggatgg
     1621 aaggcttaac cagcagccac agccagcctg tctgccggga gcccaggagc cagcttgcaa
     1681 aatcttgaaa agccaacccc ttcttagtag tcagctgcct gtgatcctga gaactgctgt
     1741 caaaacctgt gttttcactc tcagtaaatt cagacctgtg acctttaa
//
