LOCUS       NM_144518               2355 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus bMERB domain containing 1 (Bmerb1), mRNA.
ACCESSION   NM_144518
VERSION     NM_144518.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2355)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2355)
  AUTHORS   Zhang,S., Kanemitsu,Y., Fujitani,M. and Yamashita,T.
  TITLE     The newly identified migration inhibitory protein regulates the
            radial migration in the developing neocortex
  JOURNAL   Sci Rep 4, 5984 (2014)
   PUBMED   25099998
  REMARK    GeneRIF: The newly identified migration inhibitory protein (MINP)
            regulates the radial migration in the developing neocortex.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2355)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 2355)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK136859.1.
            
            On Jul 23, 2006 this sequence version replaced NM_144518.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK136859.1, AK139470.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2355
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 9.66 cM"
     gene            1..2355
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /note="bMERB domain containing 1"
                     /db_xref="GeneID:67254"
                     /db_xref="MGI:MGI:1914504"
     exon            1..257
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..766
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /note="migration inhibitory protein; uncharacterized
                     protein C16orf45 homolog"
                     /codon_start=1
                     /product="bMERB domain-containing protein 1"
                     /protein_id="NP_653101.1"
                     /db_xref="CCDS:CCDS27971.1"
                     /db_xref="GeneID:67254"
                     /db_xref="MGI:MGI:1914504"
                     /translation="MELKQSLSVHLEAEKPLRRYGAVEETAWKAEGLGSQLDIISMAE
                     TSMMPEEIELEMAKIQRLREVLVRRESELRFMMDDIQLCKDIMDLKQELQNLVAIPEK
                     EKTKLQKQREDELIQKIHRLVQKRDFLVDDAEVERLREQEEDKEMADFLRIKLKPLDK
                     VTKTSASSRAEKKAEPPPSKPTVAKTGLALIKDCCGTTQCNIM"
     exon            258..381
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /inference="alignment:Splign:2.1.0"
     exon            382..455
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /inference="alignment:Splign:2.1.0"
     exon            456..570
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /inference="alignment:Splign:2.1.0"
     exon            571..653
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /inference="alignment:Splign:2.1.0"
     exon            654..2355
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1838..1843
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /note="hexamer: AATAAA"
     regulatory      1844..1849
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /note="hexamer: AATGAA"
     polyA_site      1845
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /note="major polyA site"
     polyA_site      1856
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
     polyA_site      1861
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
     regulatory      2129..2134
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /note="hexamer: ATTAAA"
     polyA_site      2152
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
     regulatory      2248..2253
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
                     /note="hexamer: CATAAA"
     polyA_site      2285
                     /gene="Bmerb1"
                     /gene_synonym="2900011O08Rik; MINP"
ORIGIN      
        1 gagctttcag gtgctggaga ttgaagagat ggagcagctt cctcagcaac gccgggccca
       61 ttaaaacact gccgatctga gctgccttcc tccccgcagc cttcagcagg gatggagtga
      121 accagacccc tggacctgcc cgcggggaac agcaatggag ttaaagcaat ctctgtctgt
      181 tcatctggaa gccgagaagc ctctcaggcg ttatggggcg gtggaggaga cagcatggaa
      241 agcggaggga ctgggaagcc agctagacat catctccatg gctgagacca gcatgatgcc
      301 agaggagatc gagctggaga tggcgaaaat ccagcgtctc cgtgaagtcc tggtccgtcg
      361 agagtcagaa ctcaggttca tgatggatga cattcagctc tgcaaggaca tcatggacct
      421 gaagcaggag ctgcagaact tggtcgccat cccagaaaaa gaaaaaacca agctgcagaa
      481 gcagagagag gatgagctca tccagaagat ccacagactg gtacagaaga gagacttcct
      541 ggtggatgat gccgaggtgg aacgcttaag ggaacaggaa gaagacaagg aaatggctga
      601 tttcctgaga atcaagttaa aacctctaga caaagtaacc aagacttcag ccagctcccg
      661 ggcagagaag aaggcagagc ccccacctag caagccaaca gtggccaaga cagggctggc
      721 actcatcaag gattgctgtg ggaccaccca gtgcaacatc atgtagcccc tatgtgggtg
      781 ccccagagct atggggaccc ttcctcccac cctcttgtcc tcatagcccc catttcacag
      841 gggtacaaga gctttccaag gcagaaggga ttgacagcaa gcccatgact gctatcaggg
      901 gctatgggta tggcaggtgg gcccagtctg tacagcgtgt agcaatagag agcccctcac
      961 tgtcgcatga ccctccccag agcatgccca acccaggagt ctgtcttatc atttatctaa
     1021 ccaccaagaa agcccctccc ttaaaacaat agaccttcac ttttctctag gtgtatctaa
     1081 cctaccatgc aaacgaactg ggcaagggca tagccccagg tgtgtatagc tgtgaatttc
     1141 aataatctag cacagtgttg gtcccattcc ccacctaccc tcccagcttt gctgtcagat
     1201 acaagtcccg ttccctgttt gccctctccc agggactgta gcttggaggg ttccacacag
     1261 cccacacacc tcttaggctc cattgtaatc acttccctaa agacactggc ctgtctatga
     1321 aagctgagtg tgtgtggtgt tgggtttaca cctcctgctc catcccagcc tggtgtgtat
     1381 ctatctgcca gactccaggc tcttccttga tttgccatgc ccagcccaca gtggaacaga
     1441 gtagggaact gtgaccaaaa gcagatccag tgcttggacc aggtagcaga gaactgcagg
     1501 gaccaatatc aagaccagag tgaatgagaa ggggacccag aaaagatgcc aacccacatc
     1561 ctcttcaccc agggctgctg caaatgagta catacaagtg ggaaggtcac actgctggcc
     1621 caacacacac tgacaggaag cctgacccaa ctatgtccca ttgtctggtg gcgtgtttga
     1681 accagcccca caattcgtct tgtgtaactt gatgtacatt ttaaatggcc agcccagcac
     1741 agcctgtgtg aactctgtgc gtgtatgtgt gttatgactg gcctaagtac ttagcaccag
     1801 tcaagatttg ctgatgtgca aactatccat cagagaaaat aaaaatgaaa aacacacata
     1861 acatcttata tgttcttacc tttttaaatt atagatataa ctcatatact tagaaaatca
     1921 tttttaaagt acagaaagta tataaaaatt ttatctactc acaattttcc ttgtgacctc
     1981 tgatattttg acctttgtcc tcaagtcttc tcataaattt cttttgtcat gatttgcatc
     2041 atattgaaac attttatacc cagctttctt ttcagttatt attataccaa gtaggctcct
     2101 cctccatcat tcaaagttct ttgttaacat taaacatgct tcatatttat aatggttgct
     2161 tagtactcca tcttgtggat atactgttgt ctattttacc attgcctcaa tactggacat
     2221 ttagaccatc cctacgtttt cccatatcat aaatgaggtc atgaccaaca tcctgaggag
     2281 ctaaatcttc acctgaattt gtctttgtct ttttcttttt ttaaagataa actagaagta
     2341 aaattattgg tcatt
//
