LOCUS       NM_001160209            4014 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus basic leucine zipper nuclear factor 1 (Blzf1),
            transcript variant 3, mRNA.
ACCESSION   NM_001160209
VERSION     NM_001160209.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4014)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4014)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4014)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 4014)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   5  (bases 1 to 4014)
  AUTHORS   Short,B., Preisinger,C., Korner,R., Kopajtich,R., Byron,O. and
            Barr,F.A.
  TITLE     A GRASP55-rab2 effector complex linking Golgi structure to membrane
            traffic
  JOURNAL   J Cell Biol 155 (6), 877-883 (2001)
   PUBMED   11739401
REFERENCE   6  (bases 1 to 4014)
  AUTHORS   Duprez,E., Tong,J.H., Derre,J., Chen,S.J., Berger,R., Chen,Z. and
            Lanotte,M.
  TITLE     JEM-1, a novel gene encoding a leucine-zipper nuclear factor
            upregulated during retinoid-induced maturation of NB4 promyelocytic
            leukaemia
  JOURNAL   Oncogene 14 (13), 1563-1570 (1997)
   PUBMED   9129147
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK167493.1, AK029787.1 and AC105161.10.
            
            Transcript Variant: This variant (3) lacks an alternate in-frame
            exon and differs in the 5' UTR compared to variant 1. The resulting
            isoform (b) has the same N- and C-termini but is shorter compared
            to isoform a. Variants 2 and 3 both encode isoform b.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK167493.1, BC027025.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2129              AK167493.1         8-2136
            2130-2622           AK029787.1         2065-2557
            2623-2623           AC105161.10        105996-105996       c
            2624-4014           AK029787.1         2558-3948
FEATURES             Location/Qualifiers
     source          1..4014
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 71.6 cM"
     gene            1..4014
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /note="basic leucine zipper nuclear factor 1"
                     /db_xref="GeneID:66352"
                     /db_xref="MGI:MGI:1201607"
     exon            1..338
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /inference="alignment:Splign:2.1.0"
     exon            339..416
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             377..1588
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /note="isoform b is encoded by transcript variant 3"
                     /codon_start=1
                     /product="golgin-45 isoform b"
                     /protein_id="NP_001153681.1"
                     /db_xref="CCDS:CCDS48423.1"
                     /db_xref="GeneID:66352"
                     /db_xref="MGI:MGI:1201607"
                     /translation="MEKMTTLKSSENKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQ
                     PINQHVLPSPRKKVSSDSPGVLQLGKILNERTVEVEAVRIFVPKAAITHDIPTKNTKV
                     KSLGHHREELHNQAEVVTDPRKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEI
                     NRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVW
                     RSKFLASRVMADELTNFRVVLQRQNRDAQSAIQDLLSEREQFRQEMTSTQKFLEELLV
                     SLQWGREQTYSPNTQPHSTADLALTNHGLAQAIHAHLLGNVGISHQKKIPTTVEFCST
                     PAEKMAEKVLRILDPVACTESSPDNQFAESSPTTLLTTKKNIGRFHPYTRYENITFNC
                     CNHCQGELIAL"
     exon            417..853
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1053
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1182
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1402
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..4014
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2405..2410
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /note="hexamer: ATTAAA"
     polyA_site      2426
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /note="major polyA site"
     regulatory      2621..2626
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /note="hexamer: AATAAA"
     polyA_site      2643
                     /gene="Blzf1"
                     /gene_synonym="1700030G05Rik; Blzf1l; Golgin-45; Jem-1"
                     /note="major polyA site"
ORIGIN      
        1 gacccggaag tttaagcgtc cataccgctt gcattatcta ttggtacttt ttttttaagt
       61 agatatcttc cagttttcgc tttccgagcc gatacatagt agaccctgtc tctcttcatt
      121 ttacacacag cacgaagtgt cagttggtcc ttgtccttca gaagagcatt ccggaaatga
      181 aaccctgtgt aataggaagt gattagagtg agcgaggcgc tgcgtgtcag ggaggcttgg
      241 gcgggttggc ttccgagtgc caggggagtt tacaagtcag ccggctgctg agcgagtgaa
      301 gagcctgagc ggtggacatt gaagtaagga tatcacaggt cttcggtgaa agtcttggat
      361 tgtattctca ttagttatgg aaaaaatgac tacccttaaa agttcggaaa acaaaggcat
      421 ccttacttcg accccaatcc gaggagcagg agatggaatg gaaacggagg agccccctaa
      481 gtctgttgaa gtcacccacg gagtccaacc cataaatcaa catgtccttc caagtccacg
      541 gaagaaagtg tcctcagaca gcccgggcgt tcttcagctg gggaagattc ttaatgaaag
      601 aacagtggaa gttgaagctg tcagaatatt tgttcccaaa gctgctatca ctcacgacat
      661 ccccaccaag aacacaaagg ttaagtccct aggacatcac agagaagaac tccacaatca
      721 ggcagaagtg gtcacagacc caaggaagga actctcagag gtaaagaagg ttttggaaaa
      781 gctcaagaat tctgaaagga ggctacttca ggacaaagaa ggcctttcca atcagctccg
      841 agtacagaca gagataaatc gtgagttaaa gaagttactc gtggcttctg ttggggatga
      901 cccgcagtat cactttgaac gtctagcccg ggagaagaac cagctcatct tagaaaatga
      961 agcactaggt cggaacacag cccagctttc tgaacagctg gaacggatgt caatacagtg
     1021 cgatgtctgg agaagtaaat tccttgcaag cagggtaatg gcagatgagt taacaaactt
     1081 cagagtggtt ttacagcgtc agaaccgaga tgcccagagc gctatccagg atctcctgag
     1141 tgaacgagag cagtttcgtc aggaaatgac ctctacccaa aaatttttgg aagaactctt
     1201 ggtctcctta cagtggggga gagagcagac atactcccct aacacacagc cccatagcac
     1261 ggcagactta gcactcacga accatggact ggcacaagca atacatgccc atctgttggg
     1321 gaatgttggc attagccatc aaaagaagat tccaacaaca gtcgaattct gcagtacccc
     1381 agctgagaaa atggctgaaa aggttctgcg gattttggat ccagttgcct gtacagagag
     1441 ctctccggac aaccaatttg ctgaatcttc accaaccaca ttactcacta caaagaaaaa
     1501 tattggacgt ttccatccct ataccagata tgaaaatata actttcaatt gctgcaatca
     1561 ctgccagggg gagctcattg ctctttagtg tgtagtctgt tggagccatg ctcagtaccc
     1621 agagtcatta tttgggagcc cggattagta agttgctaga aataaaatca attcatcgtg
     1681 atataataca tacccatgaa gctatttcat gtactggatt ccagattatt ttttaacaaa
     1741 tatctcaggg taagaaagtg aagctttgta gatatattta aagaacagaa tacttcccag
     1801 tacatagtat ttatgctaaa aaactaaaaa gattttataa ctttctttta ggccctatat
     1861 tattattctg ttatatattt atataaacta taagcaggtt tcattttggt gcataaagca
     1921 aaaccaggca aactccaacc atgcattgta aaggggtgtg gccatatcca tcctttaccg
     1981 ctgtctggct gctttactgt agggcagcag agtcggtgtg tggctagcaa agtccatccc
     2041 tttatagagc aagtctggta gaagagctgg ggtgcatgaa aaagggattt gcagtccctt
     2101 tatggtcaca ttgtgggtac acaagaggcc ttcagaaaca ctggggtaag gggctaatcc
     2161 ttctaaacat ataataggaa aacaaaagag tattttagag ctacaacaaa tacttcaata
     2221 agtgttcatg ctgtttagtt ttggtgaggt gttctttctt tgcacggttg cagtttgaca
     2281 aaggaaacaa actcataagc accaactcat attggtgtgg agaacaacag gagacactag
     2341 cttgctaata tgatgatgga aagggatctt tagggaaaat tgtaatccat caatttaata
     2401 tagtattaaa tatattgtat aatttatcat aaggtgctca tttgtcttta aatattcaca
     2461 aaaatctgtt atcaaaaaat ataccaagtt ttacaaatta gttggagcag tgcctatcag
     2521 aaatcttcaa aaggcagatc tggtgaaatc agtgtacgtc ggggtcaaac ctgctatttt
     2581 tgtctgactc atctgagcca tttttatggc tttaaatggc aataaaggtc caatttcttt
     2641 gtggttagtg ccctttcctt tcagaagagc atgctttggc ctcagtcttc aggtggctct
     2701 gactgtttat gctgggggtt cccttcattc ccttcatagg aatggaaatt ttcatgacat
     2761 tgaatttgac tatgacttct tgtgtacaac aacaaaagca caagaaatga aaagaggaat
     2821 ttcacctaaa ttgaaaagca ttcatgcatt gaggtacaca gtagcctacc cagttagaag
     2881 tgggcagagg ctgaagagat gctgtagtct gtagaatgct gccacacaac atgagaaccc
     2941 aagtccagat ctccaagcac tcacaaaaaa cactgggtgc agcagcacac atctataacc
     3001 cagccagcac acttagagca caaacggggg agtgacattc attgagcagt ctctggctga
     3061 gttgatgagc ttcaagctaa gtggtaactc ctgcctatct cagacagtaa ggtggaaaat
     3121 gatgaaggaa gacactcagt gcataagcct ctgtccttga caggtatgcg cacacactca
     3181 acgtgtatgt gtgccataca tacttgcaaa atgagcaaat tattagttac ctaaaatgta
     3241 catgtatatt tgtgtataca catgaataga agcatatcag aagattgtca gcatcagtaa
     3301 tgagtgaagt gctatcatta ccattttcat gtaggtaaga tgactattaa caaaattgag
     3361 tatctattaa caaaaaagca agatggcaac tgtaggcaag cctgaaatct ggaactgctc
     3421 tgcttaccag cagatgtgga aagcagcttt cattgaagat ggcgccagtt ccaaggaaaa
     3481 aaagaaaaag aaaaaaatct tgcctgaccc accattctag gtttatagcc aagagaactt
     3541 gggcactgtc atagatgttt gtgtaagttt ttgaagcagt gtcgttcatg gatgctaaaa
     3601 tacaatctta atatcaatca atgattaaat aaaatccata tgacaaggaa tacattcaac
     3661 ctctaaaatg cacacttgat gcctgacatg aatattacat gaactaggtt agatacaaat
     3721 gggcaaatac tggtaccagg gtctggagaa gggcaggaaa gtgttttaaa actaaagaat
     3781 attgattttt ttttcaataa tgagtaggaa atattgcaaa gtgactccta ttgtatgcct
     3841 acttgtcttt ctgatcagaa acaaaaaaaa gagtctataa agttggaagg ggggtcttgt
     3901 gaagggggtt cagacatatg cagtacaggg attagatagg tgtggtcaga agacactatg
     3961 tatggaattc tcagtacaca agtaaccaaa aaatgcaata aaatttaaat aact
//
