LOCUS       NM_016916               2099 bp    mRNA    linear   ROD 16-JUN-2024
DEFINITION  Mus musculus bladder cancer associated protein (Blcap), transcript
            variant 2, mRNA.
ACCESSION   NM_016916
VERSION     NM_016916.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2099)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2099)
  AUTHORS   Jiang,W., Shi,J., Zhao,J., Wang,Q., Cong,D., Chen,F., Zhang,Y.,
            Liu,Y., Zhao,J., Chen,Q., Gu,L., Zhou,W., Wang,C., Fang,Z.,
            Geng,S., Xie,W., Chen,L.N., Yang,Y., Bai,Y., Lin,H. and Li,X.
  TITLE     ZFP57 dictates allelic expression switch of target imprinted genes
  JOURNAL   Proc Natl Acad Sci U S A 118 (5) (2021)
   PUBMED   33500348
REFERENCE   3  (bases 1 to 2099)
  AUTHORS   Schulz,R., McCole,R.B., Woodfine,K., Wood,A.J., Chahal,M., Monk,D.,
            Moore,G.E. and Oakey,R.J.
  TITLE     Transcript- and tissue-specific imprinting of a tumour suppressor
            gene
  JOURNAL   Hum Mol Genet 18 (1), 118-127 (2009)
   PUBMED   18836209
  REMARK    GeneRIF: Blcap is imprinted in mouse and human brain, but not in
            other mouse tissues.
REFERENCE   4  (bases 1 to 2099)
  AUTHORS   Ling,K.H., Hewitt,C.A., Beissbarth,T., Hyde,L., Banerjee,K.,
            Cheah,P.S., Cannon,P.Z., Hahn,C.N., Thomas,P.Q., Smyth,G.K.,
            Tan,S.S., Thomas,T. and Scott,H.S.
  TITLE     Molecular networks involved in mouse cerebral corticogenesis and
            spatio-temporal regulation of Sox4 and Sox11 novel antisense
            transcripts revealed by transcriptome profiling
  JOURNAL   Genome Biol 10 (10), R104 (2009)
   PUBMED   19799774
REFERENCE   5  (bases 1 to 2099)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 2099)
  AUTHORS   Pfisterer,P., Ehlermann,J., Hegen,M. and Schorle,H.
  TITLE     A subtractive gene expression screen suggests a role of
            transcription factor AP-2 alpha in control of proliferation and
            differentiation
  JOURNAL   J Biol Chem 277 (8), 6637-6644 (2002)
   PUBMED   11741941
REFERENCE   7  (bases 1 to 2099)
  AUTHORS   John,R.M., Aparicio,S.A., Ainscough,J.F., Arney,K.L., Khosla,S.,
            Hawker,K., Hilton,K.J., Barton,S.C. and Surani,M.A.
  TITLE     Imprinted expression of neuronatin from modified BAC transgenes
            reveals regulation by distinct and distant enhancers
  JOURNAL   Dev Biol 236 (2), 387-399 (2001)
   PUBMED   11476579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY718283.1, BC083339.1 and BM950751.1.
            
            On Dec 29, 2005 this sequence version replaced NM_016916.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083339.1, SRR1660815.198541.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                BY718283.1         2-37
            37-292              BC083339.1         1-256
            293-299             BM950751.1         234-240
            300-2099            BC083339.1         264-2063
FEATURES             Location/Qualifiers
     source          1..2099
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 78.4 cM"
     gene            1..2099
                     /gene="Blcap"
                     /gene_synonym="Bc10"
                     /note="bladder cancer associated protein"
                     /db_xref="GeneID:53619"
                     /db_xref="MGI:MGI:1858907"
     exon            1..114
                     /gene="Blcap"
                     /gene_synonym="Bc10"
                     /inference="alignment:Splign:2.1.0"
     exon            115..2080
                     /gene="Blcap"
                     /gene_synonym="Bc10"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..552
                     /gene="Blcap"
                     /gene_synonym="Bc10"
                     /note="bladder cancer related protein; Blcapbladder cancer
                     associated protein homolog; bladder cancer 10 kDa protein;
                     bladder cancer associated protein homolog; BLCAP apoptosis
                     inducing factor"
                     /codon_start=1
                     /product="apoptosis inducing factor BLCAP"
                     /protein_id="NP_058612.3"
                     /db_xref="CCDS:CCDS16979.1"
                     /db_xref="GeneID:53619"
                     /db_xref="MGI:MGI:1858907"
                     /translation="MYCLQWLLPVLLIPKPLNPALWFSHSMFMGFYLLSFLLERKPCT
                     ICALVFLAALFLICYSCWGNCFLYHCSDSPLPESAHDPGVVGT"
     regulatory      2060..2065
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Blcap"
                     /gene_synonym="Bc10"
                     /note="hexamer: AATAAA"
     polyA_site      2080
                     /gene="Blcap"
                     /gene_synonym="Bc10"
                     /note="major polyA site"
ORIGIN      
        1 agaagacgaa gggggcgtct ccccagctcc tgcggcgttg gtggcgagct aaggtggagg
       61 caagcagcgg cggcgacggc gacagtggcg gcagtgccat ggtggggctc gcaggatccc
      121 tgctgccttg gtgatcccgg gctgacagcc agagagcaca gcggctcagc tcctggagag
      181 agagtcgaag aaagcgaagg gcagccacct gtgcctgctg gctcccatta ggtcggttcc
      241 tgcagcggtg cctggcagcc ttggtgaagg ccctgcccgg cagagatcat gtattgcctc
      301 cagtggctgc tgcccgtcct cctcatcccc aagcccctca accccgctct gtggttcagc
      361 cactccatgt tcatgggctt ctacctgctc agcttcctcc tggaacggaa accttgcaca
      421 atatgtgcct tggttttcct ggcagccctc tttctcatct gctatagctg ctggggaaat
      481 tgtttcctgt accactgctc cgattcccca cttccggaat cagcccatga ccccggtgtt
      541 gtgggcacct aacgtctgcc gagatagctt gccaaggaag cagaagacgg gaggggaggc
      601 attgacatag gtcataaagc attggagttt caaatcccgc agtcctgcgg gtaccacatt
      661 cctaatggag ccttttggcc tgtgatgttt tatccttaca atgtgaataa tggcactgat
      721 cggtgcttct gttgtagagt cctgtagtcg tgggtggtct tatggttgtg tgttctgtca
      781 ccatctgggt cccggctgac ggattggccc acccccttgc tcattgattt ggggaatcta
      841 tacccttgat atgacctgtg tggatacagt gtagtctcaa tgtcacctcc ataacccttc
      901 ctcgtcaaga ccttcctcgt tccctcctcg tcccctttcc ccgttttccc cttggttcac
      961 ttccaacccc tttccttttt tggggagcac ctgtccaaga cagggcttgt ttttgcactt
     1021 atctcaaatt tgaagagatt gctgatgccc gagagcctcg ctttttcatc cttcgttccc
     1081 ttttgagaag gtgagacgga atcatgtctc aactgctcgt tgtctgcaga cctccagtat
     1141 ttcctctgcc tcatttttaa gaaagaagcg atggggagac attgctcttt ggcctgggta
     1201 tctgggctcc tgccttccag cccagcctct ctccctttgc tcttcctcct gtctctctca
     1261 gctgacctaa aggggccacc tcatgtctcc agtgcatgct cttcaggagg gagatgtgca
     1321 gtattctcgt agacccagtg gtccctggct gagtgaatga gaaagtatta catttttcat
     1381 agcagccatg attcccttgg taggtgtttg gatatttttg atgtgccctg tatgtatgtg
     1441 tgcactagtg tcagcgtgta tgtacacacg tatgtgtgaa tgtgtgttgt gtgtgtgttt
     1501 acataccaat acatgtgtat attccttttg aagaagcttt attgaatatg ttctgatttt
     1561 gaggtttagt agtagtagct agctgtagta ggtcctgctg cagtttttat ttagcatggg
     1621 gattgcagag cgaccagcac agtggactcc aaggtggttc agacaagacc caggggagca
     1681 gtcgccatca tcctcccacc aggagcttcc tcattgctgc gcacgtagac tgtacactat
     1741 gaagaaaaca caggaagaaa gatttggtga cttggtactt gtttgctttt ctctgcgctt
     1801 cagaaacaag tgtttgcaaa tgagactttc tcctggcccc tacccactgg ggatcagcat
     1861 ggttgttctt ccagtcggaa atgtaccccc ctcctttccc cctcttgtgt gcaagtgggg
     1921 ggggggggca ggcataggac agagctggaa gcaggcttct ggggagtggg acttagaggc
     1981 cacacttgtg aaacactcgg actgctgttg taaagctttt atttctggtg tgttcgttcc
     2041 acagctgttt gaaatgttta ataaagcttt ataaacttta aaaaaaaaaa aaaaaaaaa
//
