LOCUS       NM_001357046            3384 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus basic, immunoglobulin-like variable motif containing
            (Bivm), transcript variant 2, mRNA.
ACCESSION   NM_001357046 XM_006496002
VERSION     NM_001357046.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3384)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3384)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3384)
  AUTHORS   Yoder,J.A., Hawke,N.A., Eason,D.D., Mueller,M.G., Davids,B.J.,
            Gillin,F.D. and Litman,G.W.
  TITLE     BIVM, a novel gene widely distributed among deuterostomes, shares a
            core sequence with an unusual gene in Giardia lamblia
  JOURNAL   Genomics 79 (6), 750-755 (2002)
   PUBMED   12036287
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY210554.1, AC123800.4 and BC082584.1.
            
            On Oct 18, 2017 this sequence version replaced XM_006496002.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082584.1, SRR7652917.49441.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-171               BY210554.1         2-172
            172-227             AC123800.4         95259-95314
            228-2880            BC082584.1         1-2653
            2881-2881           AC123800.4         120179-120179
            2882-3384           BC082584.1         2655-3157
FEATURES             Location/Qualifiers
     source          1..3384
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 23.54 cM"
     gene            1..3384
                     /gene="Bivm"
                     /note="basic, immunoglobulin-like variable motif
                     containing"
                     /db_xref="GeneID:246229"
                     /db_xref="MGI:MGI:2179809"
     exon            1..239
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            240..340
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            341..941
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     CDS             467..1975
                     /gene="Bivm"
                     /codon_start=1
                     /product="basic immunoglobulin-like variable
                     motif-containing protein"
                     /protein_id="NP_001343975.1"
                     /db_xref="CCDS:CCDS14930.1"
                     /db_xref="GeneID:246229"
                     /db_xref="MGI:MGI:2179809"
                     /translation="MPNATEAGKATDPGHGEHTSENKSPEEGLQGAVPSFYTSASEAP
                     IAPRGDGHYPSSCPVTHTREKIYAICSDYAFLNQATSVYKTPSLTRSACLPDNTSLSA
                     GNTTRYIGISTSTSEIIYNEENNLENLSTGMGKLPLAWEIDKSEFDGVTTNLIHKSGN
                     VKKQFSKKKTSDKKGRHQRECLHYSPLDDVKQRKVLDLRRWYCISRPQYKTSCGISSL
                     ISCWNFLYSIMGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDH
                     FHVKGCSYVLYKPHGKNKTAGETAPGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEA
                     TPVKANKAFSRGPLSSQEVEYWILIGESSRKHPAIHCKRWADIVTDLNTQNPEFLDIR
                     HLERGLQFRKTKKVGGNLHCIIAFQRLSWQRFGFWNFPFGTITQESQHPTHVPGIAKS
                     ESEDNISKKQHGRLGRSFSASFHQDSAWKNMSSIHERRNSGYHSFRDYNGND"
     exon            942..1068
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1164
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1269
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1364
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1497
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            1498..1584
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1681
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..3350
                     /gene="Bivm"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3325..3330
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bivm"
                     /note="hexamer: AATAAA"
     polyA_site      3350
                     /gene="Bivm"
                     /note="major polyA site"
ORIGIN      
        1 ataggactag cggaaatcct gccaggagtt cacccccaac tactttcgtc ccttccctcc
       61 gtccctcact ctccctcctc ctttctcccc ccctaccttc ctttctactt cttttttcaa
      121 ctttggagca cggctttctg gcaaccttaa atactacagt tgcgcaacta gcatgtctgg
      181 agtcacagca aagatttccc aacttatatt ttgttcaagg tatccaccgc aaatggcagg
      241 tgcttcggag cctcaaagag ggggcagtgg gaagtctcct ggctcctcag agtctgaact
      301 ccagagggca tcatgtgctg catgaatctc atactcacag gatcccattt gtcagctctc
      361 aagccttttt agaatcctgt gaacatttgc caaagttgct tttttttttt tttaaagaga
      421 gggttgcggc ttcttcctag gaacagagac atctgcattt gctctcatgc ctaacgccac
      481 tgaagctgga aaagccactg atcctggaca tggtgagcac acatctgaga acaagtcacc
      541 agaagagggt ctacaaggtg ctgtaccatc tttctataca agtgcctcag aagcacccat
      601 agcgcccaga ggagatgggc attatccatc gagttgtcca gtgactcaca ctcgagagaa
      661 aatttatgcg atctgctcag attatgcctt cctcaaccag gcaacatcag tctacaaaac
      721 tcctagccta acccgctctg cttgcctccc tgataacacc tctctttctg ctggaaatac
      781 tacaagatat attggaattt caactagtac atcagaaata atctataatg aagaaaataa
      841 cttggaaaac ttgtccactg gcatgggcaa gctacctctt gcatgggaga ttgataaatc
      901 tgaatttgat ggggtgacta caaatttgat acataagtca ggcaatgtaa agaaacaatt
      961 ttccaagaag aaaacgtcgg ataaaaaagg gcggcatcag agggagtgtc tccactattc
     1021 tcctcttgat gatgttaaac aacgcaaagt gttagacctt aggcgatggt actgcataag
     1081 ccgaccacag tacaagactt catgtggtat ctcctcattg atttcttgtt ggaatttctt
     1141 atacagcata atgggagctg ggaatctccc acctattacc caagaagagg cattacatat
     1201 tttgggcttc caacccccat ttgaagatat taggtttggc cctttcactg gaaatacaac
     1261 actcatgaga tggtttagac aaattaatga ccactttcat gtgaaaggat gctcttatgt
     1321 tctatataag ccccatggga agaacaaaac agctggagaa actgctccag gggccttatc
     1381 aaagttgacc cgaggattga aagatgagtc actggcttat atctatcatt gccaaaatca
     1441 ctatttctgt ccaattggct ttgaagcaac ccctgtgaaa gctaataaag cattcagcag
     1501 ggggcccctc tcttcacaag aagtagaata ctggatttta attggagagt caagtagaaa
     1561 acatcctgcc attcactgta aaagatgggc agatattgtc actgatctaa acactcaaaa
     1621 tccagaattc ttagatatcc gacatctaga gagggggctg cagttccgga aaacaaagaa
     1681 ggttggagga aatttgcatt gcatcatagc attccagaga ctcagttggc agagatttgg
     1741 cttttggaac tttccatttg gaaccattac acaagaatca caacatccca cacatgtccc
     1801 gggaattgcc aaatctgaga gtgaggacaa tatctctaag aagcagcatg ggcgcctggg
     1861 caggtccttc agtgcgagtt tccatcagga ctcggcatgg aagaacatgt ctagcatcca
     1921 cgagaggagg aacagtggct accacagctt tagagattat aatggcaatg actgaccatg
     1981 ccaaaactta gccactggtg ttacccacac agctgttatg tacaggactg cattaggaca
     2041 tcagctggtt ttattaagtc tgtcaatagg aacagatttt gtggtacaaa acacaccctg
     2101 tagttctcta gtaaaaaagc ctacatagga ttactatggt tggcttcaaa tatacaggca
     2161 ggtaagcaca gaaccccgcc cttctaaagt taaaagtaga taagcaatct ggacaaaggg
     2221 tttcacaaaa tccaatacaa tcaaaacggc ttcaaagcaa aaacacaaat gcatttaatt
     2281 tgaaaagcat cgaaacttga actacttaag catgaagcga cttattgata cttgatccct
     2341 agcatttatt acaacacttt aattcctaag gcatcatctg tccttaaaaa atgggggcag
     2401 tcaaggtcta gtttttgctc atggttaaaa ctaatttaaa attatctttc tagtctagtt
     2461 gttctttcag tgctaacagt atccacctcc catcgttgct ttcctgaata actctcagga
     2521 ttctccaaaa agcagcagaa actactccag aaactgacct tttctctagg tgcagatagg
     2581 tgacttaggt cattgatcct gatactcttg acttggcacg tggttgtgaa atagctacaa
     2641 gaagaatata ggtctggagc gaagtctgat gttctagaac aaaccttgtt tcagggatat
     2701 agttagagag cacttggcat ccaaagtttc cttatccacg gtaacatgtg ctgtgagatg
     2761 tcacatttga cttgtctctt aatggagtca tgtgttaaca acagcactga tgtcatgttg
     2821 gcaatgtcca gctcactctg aggaagactt tgtattttca actctgagcc gtttcctttt
     2881 gtgaaacctc caagcaatta ggtgttggaa gtgtgagtta catattctgg aagtgtgagt
     2941 tcaatacttg agctcctctt tagcggctct tgttttcctt ttgctgccaa ggtgtgactc
     3001 atagccgtct atgatgctgc tctttcacgt cgtaggttta ttccaggatt caaatcagta
     3061 acttggtgat tacaaggtgc tgagtatgtt ggaaccattg caatacacct caaagggagg
     3121 tgtcggattt tgacttttta aaaaaaattt tcatttttct cttgaatttc atatccatct
     3181 atccactcat atatgtttag cctacagaat tacaaactag tcctgtttct gaagaggttc
     3241 tttagcttga aatgtaaagg actgaaagat ttgtaggtgt tgcttttgtt acttcacact
     3301 ggaactttga aaatgttttc atcaaataaa gttttgtttt ctacttttaa aaaaaaaaaa
     3361 aaaaaaaaaa aaaaaaaaaa aaaa
//
