LOCUS       NM_007464               2820 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus baculoviral IAP repeat-containing 3 (Birc3), mRNA.
ACCESSION   NM_007464
VERSION     NM_007464.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2820)
  AUTHORS   Schorn,F., Werthenbach,J.P., Hoffmann,M., Daoud,M.,
            Stachelscheid,J., Schiffmann,L.M., Hildebrandt,X., Lyu,S.I.,
            Peltzer,N., Quaas,A., Vucic,D., Silke,J., Pasparakis,M. and
            Kashkar,H.
  TITLE     cIAPs control RIPK1 kinase activity-dependent and -independent cell
            death and tissue inflammation
  JOURNAL   EMBO J 42 (22), e113614 (2023)
   PUBMED   37789765
REFERENCE   2  (bases 1 to 2820)
  AUTHORS   Wang,S., Zhao,M., Zhang,X., Su,M., Tian,Y. and Qiu,W.
  TITLE     Birc3 and Tip1 are upregulated in renal ischemia reperfusion injury
  JOURNAL   Gene 876, 147492 (2023)
   PUBMED   37209886
  REMARK    GeneRIF: Birc3 and Tip1 are upregulated in renal ischemia
            reperfusion injury.
REFERENCE   3  (bases 1 to 2820)
  AUTHORS   Li,Y., Wu,Y., Khan,I., Zhou,J., Lu,Y., Ye,J., Liu,J., Xie,X.,
            Hu,C., Jiang,H., Fan,S., Zhang,H., Zhang,Y., Jiang,X., Xu,B., Ma,H.
            and Shi,Q.
  TITLE     M1AP interacts with the mammalian ZZS complex and promotes male
            meiotic recombination
  JOURNAL   EMBO Rep 24 (2), e55778 (2023)
   PUBMED   36440627
  REMARK    GeneRIF: M1AP interacts with the mammalian ZZS complex and promotes
            male meiotic recombination.
REFERENCE   4  (bases 1 to 2820)
  AUTHORS   Biswas,D.D., Martin,R.K., Brown,L.N., Mockenhaupt,K., Gupta,A.S.,
            Surace,M.J., Tharakan,A., Yester,J.W., Bhardwaj,R., Conrad,D.H. and
            Kordula,T.
  TITLE     Cellular inhibitor of apoptosis 2 (cIAP2) restricts
            neuroinflammation during experimental autoimmune encephalomyelitis
  JOURNAL   J Neuroinflammation 19 (1), 158 (2022)
   PUBMED   35718775
  REMARK    GeneRIF: Cellular inhibitor of apoptosis 2 (cIAP2) restricts
            neuroinflammation during experimental autoimmune encephalomyelitis.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2820)
  AUTHORS   Wu,Q., Berglund,A.E., MacAulay,R.J. and Etame,A.B.
  TITLE     A Novel Role of BIRC3 in Stemness Reprogramming of Glioblastoma
  JOURNAL   Int J Mol Sci 23 (1), 297 (2021)
   PUBMED   35008722
  REMARK    GeneRIF: A Novel Role of BIRC3 in Stemness Reprogramming of
            Glioblastoma.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2820)
  AUTHORS   Kawamura,K., Sato,N., Fukuda,J., Kodama,H., Kumagai,J.,
            Tanikawa,H., Shimizu,Y. and Tanaka,T.
  TITLE     Survivin acts as an antiapoptotic factor during the development of
            mouse preimplantation embryos
  JOURNAL   Dev Biol 256 (2), 331-341 (2003)
   PUBMED   12679106
REFERENCE   7  (bases 1 to 2820)
  AUTHORS   Ishigaki,S., Liang,Y., Yamamoto,M., Niwa,J., Ando,Y., Yoshihara,T.,
            Takeuchi,H., Doyu,M. and Sobue,G.
  TITLE     X-Linked inhibitor of apoptosis protein is involved in mutant
            SOD1-mediated neuronal degeneration
  JOURNAL   J Neurochem 82 (3), 576-584 (2002)
   PUBMED   12153481
REFERENCE   8  (bases 1 to 2820)
  AUTHORS   LaCasse,E.C., Baird,S., Korneluk,R.G. and MacKenzie,A.E.
  TITLE     The inhibitors of apoptosis (IAPs) and their emerging role in
            cancer
  JOURNAL   Oncogene 17 (25), 3247-3259 (1998)
   PUBMED   9916987
  REMARK    Review article
REFERENCE   9  (bases 1 to 2820)
  AUTHORS   Liston,P., Lefebvre,C., Fong,W.G., Xuan,J.Y. and Korneluk,R.G.
  TITLE     Genomic characterization of the mouse inhibitor of apoptosis
            protein 1 and 2 genes
  JOURNAL   Genomics 46 (3), 495-503 (1997)
   PUBMED   9441758
REFERENCE   10 (bases 1 to 2820)
  AUTHORS   Rothe,M., Pan,M.G., Henzel,W.J., Ayres,T.M. and Goeddel,D.V.
  TITLE     The TNFR2-TRAF signaling complex contains two novel proteins
            related to baculoviral inhibitor of apoptosis proteins
  JOURNAL   Cell 83 (7), 1243-1252 (1995)
   PUBMED   8548810
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA556605.1, U88908.1 and AK162108.1.
            
            [WARNING] On Jul 19, 2024 this sequence was replaced by
            NM_007464.4.
            
            On Dec 20, 2007 this sequence version replaced NM_007464.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U88908.1, AK154721.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               CA556605.1         1-146
            147-1637            U88908.1           3-1493
            1638-1638           AK162108.1         1429-1429
            1639-2820           U88908.1           1495-2676
FEATURES             Location/Qualifiers
     source          1..2820
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 2.46 cM"
     gene            1..2820
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /note="baculoviral IAP repeat-containing 3"
                     /db_xref="GeneID:11796"
                     /db_xref="MGI:MGI:1197007"
     exon            1..348
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     exon            349..1293
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     CDS             441..2249
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /EC_number="2.3.2.27"
                     /note="baculoviral IAP repeat-containing 2; IAP-1; mIAP-1;
                     inhibitor of apoptosis protein 1; apoptosis inhibitor 1;
                     cellular inhibitor of apoptosis 2; RING-type E3 ubiquitin
                     transferase BIRC3"
                     /codon_start=1
                     /product="baculoviral IAP repeat-containing protein 3"
                     /protein_id="NP_031490.2"
                     /db_xref="CCDS:CCDS22812.2"
                     /db_xref="GeneID:11796"
                     /db_xref="MGI:MGI:1197007"
                     /translation="MNMVQDSAFLAKLMKSADTFELKYDFSCELYRLSTYSAFPRGVP
                     VSERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPMEKHRKLYPSCNFVQTLNPA
                     NSLEASPRPSLPSTAMSTMPLSFASSENTGYFSGSYSSFPSDPVNFRANQDCPALSTS
                     PYHFAMNTEKARLLTYETWPLSFLSPAKLAKAGFYYIGPGDRVACFACDGKLSNWERK
                     DDAMSEHQRHFPSCPFLKDLGQSASRYTVSNLSMQTHAARIRTFSNWPSSALVHSQEL
                     ASAGFYYTGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLLRIKGQEFVSQV
                     QAGYPHLLEQLLSTSDSPEDENADAAIVHFGPGESSEDVVMMSTPVVKAALEMGFSRS
                     LVRQTVQWQILATGENYRTVSDLVIGLLDAEDEMREEQMEQAAEEEESDDLALIRKNK
                     MVLFQHLTCVTPMLYCLLSARAITEQECNAVKQKPHTLQASTLIDTVLAKGNTAATSF
                     RNSLREIDPALYRDIFVQQDIRSLPTDDIAALPMEEQLRKLQEERMCKVCMDREVSIV
                     FIPCGHLVVCKDCAPSLRKCPICRGTIKGTVRTFLS"
     exon            1294..1393
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1472
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1521
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1761
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..2013
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2055
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     exon            2056..2813
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2775..2780
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /note="hexamer: AATAAA"
     polyA_site      2813
                     /gene="Birc3"
                     /gene_synonym="Api1; Api2; Birc2; C-IAP2; cIAP-1; cIAP-2;
                     cIAP1; cIAP2; HIAP2; IAP1; IAP2; MIAP1; MIAP2; MIHB; MIHC;
                     RNF49"
                     /note="major polyA site"
ORIGIN      
        1 aagagccaag agccttcaag taaaaacttt cagtaaatga cacgaagagg agctgggtcc
       61 aggaagtcac gcacagaaga gccacggaaa tccccagcca gggtggccac caagggtgag
      121 gaggaagtgc gtctggtttt caccctggag ttccccggag ccctggagga aagcaccgca
      181 ggtctgagca gccctgagcc gggcagggtg ggggcagtgg ctaaggccta gctggggacg
      241 atttaaaggt atcgcgccac ccagccacac cccacaggcc aggcgagggt gccacccccg
      301 gagatcagag gtcattgctg gcgttcagag cctaggaagt gggctgcggt atcagcctag
      361 cagtaaaacc gaccagaagc catgcacaaa actacatccc cagagaaaga cttgtccctt
      421 cccctccctg tcatctcacc atgaacatgg ttcaagacag cgcctttcta gccaagctga
      481 tgaagagtgc tgacaccttt gagttgaagt atgacttttc ctgtgagctg taccgattgt
      541 ccacgtattc agcttttccc aggggagttc ctgtgtcaga aaggagtctg gctcgtgctg
      601 gcttttacta cactggtgcc aatgacaagg tcaagtgctt ctgctgtggc ctgatgctag
      661 acaactggaa acaaggggac agtcccatgg agaagcacag aaagttgtac cccagctgca
      721 actttgtaca gactttgaat ccagccaaca gtctggaagc tagtcctcgg ccttctcttc
      781 cttccacggc gatgagcacc atgcctttga gctttgcaag ttctgagaat actggctatt
      841 tcagtggctc ttactcgagc tttccctcag accctgtgaa cttccgagca aatcaagatt
      901 gtcctgcttt gagcacaagt ccctaccact ttgcaatgaa cacagagaag gccagattac
      961 tcacctatga aacatggcca ttgtcttttc tgtcaccagc aaagctggcc aaagcaggct
     1021 tctactacat aggacctgga gatagagtgg cctgctttgc gtgcgatggg aaactgagca
     1081 actgggaacg taaggatgat gctatgtcag agcaccagag gcatttcccc agctgtccgt
     1141 tcttaaaaga cttgggtcag tctgcttcga gatacactgt ctctaacctg agcatgcaga
     1201 cacacgcagc ccgtattaga acattctcta actggccttc tagtgcacta gttcattccc
     1261 aggaacttgc aagtgcgggc ttttattata caggacacag tgatgatgtc aagtgttttt
     1321 gctgtgatgg tgggctgagg tgctgggaat ctggagatga cccctgggtg gaacatgcca
     1381 agtggtttcc aaggtgtgag tacttgctca gaatcaaagg ccaagaattt gtcagccaag
     1441 ttcaagctgg ctatcctcat ctacttgagc agctattatc tacgtcagac tccccagaag
     1501 atgagaatgc agacgcagca atcgtgcatt ttggccctgg agaaagttcg gaagatgtcg
     1561 tcatgatgag cacgcctgtg gttaaagcag ccttggaaat gggcttcagt aggagcctgg
     1621 tgagacagac ggttcagtgg cagatcctgg ccactggtga gaactacagg accgtcagtg
     1681 acctcgttat aggcttactc gatgcagaag acgagatgag agaggagcag atggagcagg
     1741 cggccgagga ggaggagtca gatgatctag cactaatccg gaagaacaaa atggtgcttt
     1801 tccaacattt gacgtgtgtg acaccaatgc tgtattgcct cctaagtgca agggccatca
     1861 ctgaacagga gtgcaatgct gtgaaacaga aaccacacac cttacaagca agcacactga
     1921 ttgatactgt gttagcaaaa ggaaacactg cagcaacctc attcagaaac tcccttcggg
     1981 aaattgaccc tgcgttatac agagatatat ttgtgcaaca ggacattagg agtcttccca
     2041 cagatgacat tgcagctcta ccaatggaag aacagttgcg gaaactccag gaggaaagaa
     2101 tgtgtaaagt gtgtatggac cgagaggtat ccatcgtgtt cattccctgt ggccatctgg
     2161 tcgtgtgcaa agactgcgct ccctctctga ggaagtgtcc catctgtaga gggaccatca
     2221 agggcacagt gcgcacattt ctctcctgaa caagactaat ggtccatggc tgcaacttca
     2281 gccaggagga agttcactgt cactcccagc tccattcgga acttgaggcc agcctggata
     2341 gcacgagaca ccgccaaaca cacaaatata aacatgaaaa acttttgtct gaagtcaaga
     2401 atgaatgaat tacttatata ataattttaa ttggtttcct taaaagtgct atttgttccc
     2461 aactcagaaa attgttttct gtaaacatat ttacatacta cctgcatcta aagtattcat
     2521 atattcatat attcagatgt catgagagag ggttttgttc ttgttcctga aaagcaggga
     2581 ttgcctgcac tcctgaaatt ctcagaaaga tttacaatgt tggcatttat ggttcagaaa
     2641 ctagaatctt ctcccgttgc tttaagaacc gggagcacag atgtccatgt gttttatgta
     2701 tagaaattcc tgttatttat tggatgacat tttagggata tgaaattttt ataaagaatt
     2761 tgtgagaaaa agttaataaa gcaacataat tacctctttt tttttaaaga aaaaaaaaaa
//
