LOCUS       NM_007544               1907 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus BH3 interacting domain death agonist (Bid), mRNA.
ACCESSION   NM_007544
VERSION     NM_007544.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1907)
  AUTHORS   Soma,S., Murakami,K., Fukuchi,Y., Kunimoto,H. and Nakajima,H.
  TITLE     O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse
            Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL
            and Oxidative Phosphorylation
  JOURNAL   Stem Cells 42 (1), 55-63 (2024)
   PUBMED   37813816
REFERENCE   2  (bases 1 to 1907)
  AUTHORS   Abele,T.J., Billman,Z.P., Li,L., Harvest,C.K., Bryan,A.K.,
            Magalski,G.R., Lopez,J.P., Larson,H.N., Yin,X.M. and Miao,E.A.
  TITLE     Apoptotic signaling clears engineered Salmonella in an
            organ-specific manner
  JOURNAL   Elife 12, 89210 (2023)
   PUBMED   38055781
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1907)
  AUTHORS   Wu,B., Wu,B., Benkaci,S., Shi,L., Lu,P., Park,T., Morrow,B.E.,
            Wang,Y. and Zhou,B.
  TITLE     Crk and Crkl Are Required in the Endocardial Lineage for Heart
            Valve Development
  JOURNAL   J Am Heart Assoc 12 (18), e029683 (2023)
   PUBMED   37702066
REFERENCE   4  (bases 1 to 1907)
  AUTHORS   Leibowitz,B.J., Zhao,G., Xia,W., Wang,Y., Ruan,H., Zhang,L. and
            Yu,J.
  TITLE     mTOR inhibition suppresses Myc-driven polyposis by inducing
            immunogenic cell death
  JOURNAL   Oncogene 42 (24), 2007-2016 (2023)
   PUBMED   37138032
REFERENCE   5  (bases 1 to 1907)
  AUTHORS   Ke,F.S., Holloway,S., Uren,R.T., Wong,A.W., Little,M.H.,
            Kluck,R.M., Voss,A.K. and Strasser,A.
  TITLE     The BCL-2 family member BID plays a role during embryonic
            development in addition to its BH3-only protein function by acting
            in parallel to BAX, BAK and BOK
  JOURNAL   EMBO J 41 (15), e110300 (2022)
   PUBMED   35758142
  REMARK    GeneRIF: The BCL-2 family member BID plays a role during embryonic
            development in addition to its BH3-only protein function by acting
            in parallel to BAX, BAK and BOK.
REFERENCE   6  (bases 1 to 1907)
  AUTHORS   Gross,A., Yin,X.M., Wang,K., Wei,M.C., Jockel,J., Milliman,C.,
            Erdjument-Bromage,H., Tempst,P. and Korsmeyer,S.J.
  TITLE     Caspase cleaved BID targets mitochondria and is required for
            cytochrome c release, while BCL-XL prevents this release but not
            tumor necrosis factor-R1/Fas death
  JOURNAL   J Biol Chem 274 (2), 1156-1163 (1999)
   PUBMED   9873064
REFERENCE   7  (bases 1 to 1907)
  AUTHORS   Wang,K., Yin,X.M., Copeland,N.G., Gilbert,D.J., Jenkins,N.A.,
            Keck,C.L., Zimonjic,D.B., Popescu,N.C. and Korsmeyer,S.J.
  TITLE     BID, a proapoptotic BCL-2 family member, is localized to mouse
            chromosome 6 and human chromosome 22q11
  JOURNAL   Genomics 53 (2), 235-238 (1998)
   PUBMED   9790773
REFERENCE   8  (bases 1 to 1907)
  AUTHORS   Li,H., Zhu,H., Xu,C.J. and Yuan,J.
  TITLE     Cleavage of BID by caspase 8 mediates the mitochondrial damage in
            the Fas pathway of apoptosis
  JOURNAL   Cell 94 (4), 491-501 (1998)
   PUBMED   9727492
REFERENCE   9  (bases 1 to 1907)
  AUTHORS   Footz,T.K., Birren,B., Minoshima,S., Asakawa,S., Shimizu,N.,
            Riazi,M.A. and McDermid,H.E.
  TITLE     The gene for death agonist BID maps to the region of human 22q11.2
            duplicated in cat eye syndrome chromosomes and to mouse chromosome
            6
  JOURNAL   Genomics 51 (3), 472-475 (1998)
   PUBMED   9721221
REFERENCE   10 (bases 1 to 1907)
  AUTHORS   Wang,K., Yin,X.M., Chao,D.T., Milliman,C.L. and Korsmeyer,S.J.
  TITLE     BID: a novel BH3 domain-only death agonist
  JOURNAL   Genes Dev 10 (22), 2859-2869 (1996)
   PUBMED   8918887
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK161235.1 and AK077657.1.
            
            On Feb 14, 2018 this sequence version replaced NM_007544.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC002031.1, AK045731.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1894              AK161235.1         19-1912
            1895-1907           AK077657.1         1874-1886
FEATURES             Location/Qualifiers
     source          1..1907
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 57.02 cM"
     gene            1..1907
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /note="BH3 interacting domain death agonist"
                     /db_xref="GeneID:12122"
                     /db_xref="MGI:MGI:108093"
     exon            1..91
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            92..157
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..733
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /note="p22 BID"
                     /codon_start=1
                     /product="BH3-interacting domain death agonist"
                     /protein_id="NP_031570.2"
                     /db_xref="CCDS:CCDS20486.1"
                     /db_xref="GeneID:12122"
                     /db_xref="MGI:MGI:108093"
                     /translation="MDSEVSNGSGLGAEHITDLLVFGFLQSSGCTRQELEVLGRELPV
                     QAYWEADLEDELQTDGSQASRSFNQGRIEPDSESQEEIIHNIARHLAQIGDEMDHNIQ
                     PTLVRQLAAQFMNGSLSEEDKRNCLAKALDEVKTAFPRDMENDKAMLIMTMLLAKKVA
                     SHAPSLLRDVFHTTVNFINQNLFSYVRNLVRNEMD"
     exon            158..368
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            369..508
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            509..721
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            722..1895
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1875..1880
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1895
                     /gene="Bid"
                     /gene_synonym="2700049M22Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggtggagta gagcgccggg ccgagtgtgg ctccgcaaac ctttgcctta gcccgttcgc
       61 cgcccggtac cggcgcagcg gcgtctgcgt ggtgattccc tggactctgt gagctggcag
      121 tgcttggagc tacacagctt gtgccatgga ctctgaggtc agcaacggtt ccggcctggg
      181 ggccgagcac atcacagacc tgctggtgtt cggctttctc caaagctctg gctgtactcg
      241 ccaagagctg gaggtgctgg gtcgggaact gcctgtgcaa gcttactggg aggcagacct
      301 cgaagacgag ctgcagacag atggcagcca ggccagccgc tccttcaacc aaggaagaat
      361 agagccagat tctgaaagtc aggaagaaat catccacaac attgccagac atctcgccca
      421 aataggcgat gagatggacc acaacatcca gcccacactg gtgagacagc tagccgcaca
      481 gttcatgaat ggcagcctgt cggaggaaga caaaaggaac tgcctggcca aagcccttga
      541 tgaggtgaag acagccttcc ccagagacat ggagaacgac aaggccatgc tgataatgac
      601 catgctgttg gccaaaaaag tggccagtca cgcaccatct ttgctccgtg atgtcttcca
      661 cacgactgtc aactttatta accagaacct attctcctat gtgaggaact tggttagaaa
      721 cgagatggac tgaggagccc gcacaagccc gatggtgaca ctgcctccag aggaaccgcg
      781 accatggaaa gaccttggcc tgaagacagg tcccagagaa cagctgtctc cctatttcca
      841 ggtggtggga accccaagct ggtgattcac tggacatctc tgcgttcagc ttgagtgtat
      901 ctgaagagtt tacgccggct cctgcatcca caccatgtac ctttgtccta tcagctgtat
      961 gggttcccac ttgggaatga aacttaacag caggctgtaa ggcagaaaag catctttgta
     1021 atgccaagtg actgttcctg agagccagct ctgggctgtc ttcaccatgt aggtgggctt
     1081 ctgtctaagg agaacagcat taggagaggt gcatcggccc atgagcgtga agtccaccca
     1141 gcctagtgga cactgaagtg ctcacaaggc ctccacctgc ctttgtaaaa gccgaatggc
     1201 tgatctcaaa ccatgggaag cccgaccgcc ccacccctcc tcaccccagc gtttagctgt
     1261 ttcaggggtc agctattatc tcaagatttc tatccaagtg gaaacaaact gaatcatgca
     1321 cacgacttat ctgtgtggtg tcagttacac tcaggctctt gctacggaat gcaaagaaca
     1381 actcacatac cagtgtcaaa cagaatgcac agaagagacc taaaacagca gcaggtcact
     1441 cggttcacaa aaggtgactc ccagtcaagt ctgacacact gtcttggttg tagagcacag
     1501 ctgccatcct ctttccctgg gtaacatcac agaagattcc atatcaaaag caaatgttcc
     1561 ctccgcttct gtatttcaga gacaaggcct cactgtatcc tcaagcgttg ttacgtcttg
     1621 tgctgaactt tgcttaaagc tgggatcgtc agcacgagcc gccacagcct acaagtattc
     1681 tagttctgaa ctcatcccag ccatggtggc tgtgatggct tgggtgtatc atacctgtaa
     1741 attagtggat ttttctttag gaacatgacc tttgggtgag tataattgag aaattatttt
     1801 aattcagaaa gtacttttca ttgtgttcta aaaatatgtg aattgtctta agtggtagaa
     1861 atttgtttct tcaaaataaa aggctcttct ctagaaaaaa aaaaaaa
//
