LOCUS       NM_178663               3837 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus BEN domain containing 7 (Bend7), transcript variant 1,
            mRNA.
ACCESSION   NM_178663
VERSION     NM_178663.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3837)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3837)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928550.20, AK030428.1 and AL807778.10.
            
            On Jun 19, 2010 this sequence version replaced NM_178663.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK030428.1, SRR7652917.715775.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-314               AL928550.20        92538-92851
            315-2616            AK030428.1         2-2303
            2617-3837           AL807778.10        77847-79067
FEATURES             Location/Qualifiers
     source          1..3837
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 2.88 cM"
     gene            1..3837
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /note="BEN domain containing 7"
                     /db_xref="GeneID:209645"
                     /db_xref="MGI:MGI:2443100"
     exon            1..462
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             402..1706
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /note="isoform 1 is encoded by transcript variant 1; BEN
                     domain-containing protein 7"
                     /codon_start=1
                     /product="BEN domain-containing protein 7 isoform 1"
                     /protein_id="NP_848778.1"
                     /db_xref="CCDS:CCDS15658.1"
                     /db_xref="GeneID:209645"
                     /db_xref="MGI:MGI:2443100"
                     /translation="MEFSERKRSRKSQSFKLVSRDYHHEVYKISEFSNDVNGETKETQ
                     PIYLGDESMEIKKQITGMRRLLNDSTGRIYQRVGKEGEKLKQEPQVVDLVWPQRSNSS
                     TEASQGLHSNSRGAWNELPTQSGQFSGQSGPRSRTFQTQPHISASSNGELPGVNSIVG
                     SNCCTCNCQSTLQAILQELKTMRKLMQFQAVGTQNRQQPPISLMCSQRTAVSRKRNKK
                     KKVLPKTVQPVTAVEPKPSPLETEKKPAASATRPPGLQAAERTSTEENHVLGFGIVLE
                     SPSSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDKTLANSLPNG
                     KRKRGFNDNRKGLDQNIVGAIKVFTENYCTANHVDKLPGPRDWVQILQDQIKLARRRL
                     KRGSAEVADGDERLDRISLPPTGHTFVIKRETPEDPEPGSVA"
     exon            463..546
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            547..849
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            850..972
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1244
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1470
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1590
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1644
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1645..3837
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3814..3819
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3833
                     /gene="Bend7"
                     /gene_synonym="1110017O21Rik; E130319B15Rik"
                     /note="major polyA site"
ORIGIN      
        1 acccgccgcc gccgccctcc ctcggctcgc cgcgtccccc gggccgcgtc cgcaggctga
       61 gcccaggcgg gccgcggcga gcaccccaca gctccgcgcc ccagcccggc cccgctccca
      121 acggaaagtt gggctgcggc gggctgcgtt cgggaaagag cgaggcggca tgaaggggca
      181 ccgaggggtc gcctaagaca ccggggaggc ggagccgcgc gcggggacaa cttcgccccg
      241 ggcgcgcaac ccccggccgg gctcgcggtg gttcctcccg tccctcggcc tcccccgccg
      301 atcgcgacgc ggaccttggt cccggcggct ccgcggcggt gacacgagcc cgcctcagcc
      361 gccgcctcag tctcctgccg cgccgccacc ttgcccgcac catggagttc tcggagagga
      421 aaagaagcag gaaatcccag agcttcaaac tggtgagccg agattatcac catgaggtgt
      481 ataaaatctc agaattcagc aatgatgtta atggggagac caaagagaca caacccattt
      541 acttaggaga cgaaagcatg gaaattaaaa aacaaattac ggggatgaga agattactga
      601 atgacagcac tggaaggata tatcagcgtg tcggcaaaga aggagaaaaa ttaaaacaag
      661 agccgcaggt tgtggattta gtctggcctc agcggtccaa ctcttccacc gaggcctcac
      721 agggcctcca ctctaattca cgtggggcgt ggaatgaact accaacccaa agcgggcagt
      781 tctcagggca gtctggtcca cgctccagaa ccttccagac tcagccccac atctctgcaa
      841 gttccaatgg agaacttcca ggggtgaatt caatagtcgg atccaactgc tgtacttgta
      901 actgccagtc aaccttgcag gccattctcc aagagctcaa gaccatgagg aaattaatgc
      961 agtttcaagc agttggaact caaaacagac aacaaccccc aatttccctt atgtgctccc
     1021 agcgaaccgc cgtctcacgc aagagaaata aaaagaaaaa agtgcttccg aagactgtgc
     1081 aacctgtgac ggctgtggaa ccaaagccca gtcccttgga aactgagaag aagccagcag
     1141 cctcggccac aaggccacca ggtctccaag ctgcagagcg cacctccacc gaggagaacc
     1201 acgtcctggg atttggcatt gttctggaat cgccgtcctc agatccagaa gtgcaacttg
     1261 ctgaaggctt cgatgtgttt atgcccaaat ctcagctgga ctctatactg tcaaactaca
     1321 ctcgctcagg aagccttctg tttagaaaac tggtgtgtgc attttttgac gacaagactt
     1381 tggctaactc cttacccaac ggaaagcgga aaagagggtt caatgacaac cggaaaggac
     1441 tagaccaaaa cattgtgggt gcaataaaag tctttacaga aaattactgt actgcgaatc
     1501 atgtggataa acttcctggc cccagagact gggtgcagat tctgcaggat cagattaaac
     1561 tggccagaag aaggttgaaa cgaggctcag cagaggtagc tgacggtgat gaaagactgg
     1621 accgcatctc tctaccccca acaggtcata catttgtcat caagagagag accccagagg
     1681 acccagaacc aggttccgtg gcctagactt gcattctgga acattcttcg tttcctccaa
     1741 ggtccatgta gcagctacag atcctgcagt gtgggtgttc tatgatggct tgtcctgtcc
     1801 gaataatttc tttgtaacat gtgctatcac aactctggtt tggcataata cttatttaaa
     1861 gaaccatgct tacagttgct accctgtaag cgtcccgtgt gtgtgaccca ccgtaaagaa
     1921 gccattccct tcctgtctct gtccgttcac agactgggtg tgaagacagc agtctttcta
     1981 aacatatttt attgtgaatt gcttagctgc atgcagagag gaaaccttct cttccaggac
     2041 tgacagaggc tacaaggcag cgctaactag cccctcttca gcttagagaa ggaaacagtt
     2101 gttctgagag acaggagagc tcctacctgg ccagtgaaat cgtttctgac atcagtcata
     2161 gtaacccgga cagacatttg gaactggaga agtacaagcg atgtaagaat ccttaggaaa
     2221 taaaatcttt cacataattt ataatgacgt gatgacaaaa aaataataat aactcaaagt
     2281 aagcagccat ctgcttggga gccgtcaagc atttaaacat ggtttaaact gagcagcctg
     2341 ggctgtgacc attttcatgt tcattctgta gtctgtctgg tccctcaccc gcctgccttc
     2401 tgctttttgt aagaaaaaaa atctggcttt attttaaaga aatctttgct gtggggataa
     2461 ttgttttaca gacatattta cctccacatt tgttttgcta atgaaatcat tcattaaaaa
     2521 taccacctta gaaagccttg cgtttacacc gtatttatgg tataaagcaa actgccttga
     2581 atcttgggca cttgacccaa aggccaaaaa tagctgttaa agaaaaaaaa tgtgactctc
     2641 atccaccaaa ccccagggat aaaaacctgc caggacaaaa gcttagcctt tgccctactc
     2701 ttggtgcagc gatgggttaa agccgacagt gtgcttcaag gactcggtgc ttcaaggacc
     2761 agtcccactc cgagctttgc cagtgagaga gccgagaggt gggttgccta ggaccaaggt
     2821 acccttcgtg gccagctggc catagaacct ggatatcctt gggaccctgt ccattgcact
     2881 gcaccatgcc acacggaaca ctaaagatag gatcagaaca ctattccact gagaccagct
     2941 agggaaagtg ataggtgata tccctggaat gtgacaaagt ccgcttctag gtgttgctcc
     3001 tacagtcagt ctccagagga gatagcaaca tctcacagat gcacctttta tttctctccg
     3061 ctcggaagct atggggacag cgtggaaatc actcccatcc tgcagtcagc taccatagat
     3121 ttccgtttcc cgctggccct aatccctgtg ttttatccag gggtctgatg agctgcaggc
     3181 agaccaggac tctcattcac tctgcagcag gtcctgaaaa agaattgtct tctgcctccc
     3241 aggatgaaat actgctcaag gggactagag aagctgagtt agcgcctgtc acttgattaa
     3301 atgagggtga atttgttttc agtacaggga gaacatagac tcacaactgg aggtcagttg
     3361 ggtgtgaaca ataaaccttc agaaaacact tccttccaag cctggggtga cagcttggag
     3421 ttttcagtac ttgaggaggg gtgggattgt ttgactcaca gatacgtgca atgggttcac
     3481 aggttgggaa ggcagagcaa aactgtaaca gtacaaccat actttgtaag tttacattgt
     3541 atttgtgtta acttaccgtg actactgttc agctttgttt agaaaccctt tttataggct
     3601 ttcttagcaa aaaaacaaaa aagtccatat cgatggatga cacgtctcag tcttctgtac
     3661 atatatttta ttaatatgta aatattcaga tttttaaaat tataatgttc ttttaaaaga
     3721 attcaatgca aagctagctg tgaaaatggt gtgtaacact gtgttgtgat ttcaactccc
     3781 aagacgccct ttatgtccat tctggaaaaa tacaataaat tactttaatt gaatgca
//
