LOCUS       NM_001141922            3315 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus brain expressed, associated with Nedd4, 1 (Bean1),
            transcript variant 1, mRNA.
ACCESSION   NM_001141922 XM_486154 XM_913080
VERSION     NM_001141922.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3315)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3315)
  AUTHORS   Khang,R., Jo,A., Kang,H., Kim,H., Kwag,E., Lee,J.Y., Koo,O.,
            Park,J., Kim,H.K., Jo,D.G., Hwang,I., Ahn,J.Y., Lee,Y., Choi,J.Y.,
            Lee,Y.S. and Shin,J.H.
  TITLE     Loss of zinc-finger protein 212 leads to Purkinje cell death and
            locomotive abnormalities with phospholipase D3 downregulation
  JOURNAL   Sci Rep 11 (1), 22745 (2021)
   PUBMED   34815492
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3315)
  AUTHORS   Timmermans,S. and Libert,C.
  TITLE     Overview of inactivating mutations in the protein-coding genome of
            the mouse reference strain C57BL/6J
  JOURNAL   JCI Insight 3 (13), 121758 (2018)
   PUBMED   29997285
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3315)
  AUTHORS   Jolliffe,C.N., Harvey,K.F., Haines,B.P., Parasivam,G. and Kumar,S.
  TITLE     Identification of multiple proteins expressed in murine embryos as
            binding partners for the WW domains of the ubiquitin-protein ligase
            Nedd4
  JOURNAL   Biochem J 351 Pt 3 (Pt 3), 557-565 (2000)
   PUBMED   11042109
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132390.4 and AC115718.15.
            
            On Jan 31, 2022 this sequence version replaced NM_001141922.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC138184.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164136
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-415               AC132390.4         6772-7186           c
            416-521             AC115718.15        71609-71714         c
            522-630             AC115718.15        71238-71346         c
            631-882             AC115718.15        42188-42439         c
            883-993             AC115718.15        39331-39441         c
            994-1144            AC115718.15        38193-38343         c
            1145-3315           AC115718.15        34259-36429         c
FEATURES             Location/Qualifiers
     source          1..3315
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.04 cM"
     gene            1..3315
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /note="brain expressed, associated with Nedd4, 1"
                     /db_xref="GeneID:65115"
                     /db_xref="MGI:MGI:1929597"
     exon            1..415
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /inference="alignment:Splign:2.1.0"
     exon            416..521
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /inference="alignment:Splign:2.1.0"
     exon            522..630
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /inference="alignment:Splign:2.1.0"
     exon            631..882
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /inference="alignment:Splign:2.1.0"
     exon            883..993
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1144
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..3315
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3293..3298
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /note="hexamer: AATAAA"
     polyA_site      3315
                     /gene="Bean1"
                     /gene_synonym="Bean"
                     /note="major polyA site"
ORIGIN      
        1 atctcagcaa tgacccgggc cgtggcgcca ccgagctgag accggggagc cgcgccgccg
       61 ccgaggaggg cccaagaggg tgacggtgga acgagcggcg gcgcggggac cgcgacggag
      121 ggacgggcgg ggctgctgtt cctgctgcag ggcagggcag ggcagggcag ggccccggag
      181 accgccggcg gctgtttgcc cgcggatcga gggcgcgggt ccgttctgcc cggccccgcc
      241 ggtgcgcccc gcccctgcac gcacagcagg cccaggcgaa gcggctggga cgccccagcc
      301 cagccggagc gccacggcat ccgagcggga gccggagccc gagcgggacc ggagctggag
      361 ccgaagctgg agccggcact gcggcgcacg gagcggagcg ccgcagccaa gccgagtctg
      421 ctttcctcta ggaaatgagg actccagtct ttaagaattg gtccatgcct tacagcccca
      481 aggcactggg gatgctgtag cccatggaag acgtggaaac agcgagtaga ggggcctccc
      541 ccctccaaga agtcagagct gtgctcgtgg gcaggctggc tccgctgttc tgctccaagg
      601 attacatgtc cttcaaacgc ccttgcccct tagcacgata caaccgtacc agctatttct
      661 accctaccac gttctccgag agctctgagc acagccacct gctggtgtct ccggtgctgg
      721 tggcgagcgc tgtcataggt gtggtcatca ctctctcctg catcaccatc attgtgggaa
      781 gcatcagaag ggacagacag gcccggatcc agcgacacca ccatcgtcac cgccgccatc
      841 atcaccatca ccgccaccgc aggcgccgac accgagaata cgtcgcaggg gtgacatcca
      901 tgagagcagg acccgtgtgt ggtccacccc acctgcagcc cagaggaggt ttttcagagg
      961 ctatggaagg actgaccttc acgagtcttt gtgcatctgg aggacacaca cacagccgtt
     1021 ctagccccag gatgccctat gcctgcagcc ctgctgagga ctggccaccg cccttggacg
     1081 tcagctccga gggggatgtg gatgtcacag tgctctggga gctgtaccca gattctccac
     1141 caggctatga ggaatgcatg ggaccagggg ccactcagct gtatgtcccc acggatgcac
     1201 caccgcccta ctccatgact gactcctgtc ccaggctgaa tggcgccctt gactcagaca
     1261 gcggccagag ccgcagccac cgtcagcaag agcagaggac ccagggtcag agcagactcc
     1321 acactgtctc catggacaca ctgccacctt atgaagctgt gtgtgggaca ggctctccat
     1381 ctgacctgct gccattgcca ggaccagaac catggccaag taactcccag ggctcaccca
     1441 tcccaaccca ggctccgatg cccagccctg aaaggattgt gtgagtggcc aagctcataa
     1501 attccgctgg tctttccagg ctaccctctc tcctccaggc atacaggtgc acacacaacc
     1561 catgcacatg catatatatg actatcaata tatactgaca tatccccaag tgcttacact
     1621 gacacaaccc acacatatgt agacacctgc atatgcacat gtcccactac tacacaaact
     1681 cacctgggaa ggttttcttt ggatgaggtg ttccctacat ggtatctctt cctccccagc
     1741 ctggtgcctg gtggccgtgc ctctctgaac agtgctgggc agaggtgaga taggaaaccc
     1801 aattttctat cctctcccca gcctcctcta ggctatggcc acaatctgat tctcctgcag
     1861 agactgcttg gtcagcttcc tgccataact cctaccccag ggcttatcct attgggagct
     1921 gagacaggtc ccaataaggt cccactgtgc actgtgccta tctctcaact ccagggctga
     1981 agagccacaa tgtcaccgtc ctgccacttc cgaggtggga gagaaacagg tctggtggct
     2041 taggcatgac ctggaggtcc tcacagccca tttagcctgt ctcgatgtcc ttagtgtggc
     2101 ggtgctagtg gggttagctc agacacccac cctaagtttc agggggagac aggcccttgg
     2161 gcctgtatcg tggaggaaca acacagttct tctaatgtct gtgccaggat tgagagctca
     2221 agagaaacaa ggtgtgggca gccccataca cacataatgc ttcctagaca tcactcagag
     2281 gaggcacaga agagtccact gctcagtaag tgcccagcca gctctggtga cctgggtgta
     2341 agaggtctca gaccaaccaa agagccagcg ctgtcatcca gggtggtaac tcccagctgg
     2401 ggactgggct gatgaagtct ggccttgcct ctctgggata tacacagaga caacacacac
     2461 acatgtaccc cacaaaaaaa aaaaaaaaaa aaaaaaagca aaaaaaaaac aaaaaaaact
     2521 tcatgtcact atgagaccag tgtctgctgc caacatccca tcacggaagc aggtgtgtgg
     2581 aggcagccag ttggagatag gctcagatat tagcctttga gctccagcga tgtgatctcc
     2641 atcgaagact atataaggtg acgaggccat ctttgaagac ccggcttgcc aaagctaagc
     2701 acctttgagg aggatcctgt cagcactgcc gctggcaggg agtgagacct cctgcctccc
     2761 ggactcctac cttctgacgg tcatcccaga agagcagacc catccccact gaaccccttc
     2821 ccacattcaa ctcctccaat gaagggctaa gaaaattcat caatcccttt cctaagcaga
     2881 ggggtagcaa ggatttttat tttctataga gaaagcattt attctgatgc agagccgaaa
     2941 gggcccaacc accagttctg tagcatctag gcggcagcgg ctgcaggctg cgggcagcac
     3001 cctagagtcc caggcctggg ggagggagcc ttgtttacaa gcccttttgc ccacctttgt
     3061 ggcgttctgc tttctaggca aagatgtctg tctgtggtac tgtccagcct ttaaaacaca
     3121 ccccggggat gagactcttt ttaagaaagg cagtctgttt ctagagctct ggaaagtggt
     3181 gggggcagaa aaacatcccc gcctattcac cacgtcggag ggatctgcgg aacagctttt
     3241 ctccttccta ggttaggctg aataagcagc aatgtatctt ttctgtactc aaaataaatg
     3301 ctcattatca acaaa
//
