LOCUS       NM_029510               6959 bp    mRNA    linear   ROD 09-JUL-2024
DEFINITION  Mus musculus BCL6 interacting corepressor (Bcor), transcript
            variant a, mRNA.
ACCESSION   NM_029510
VERSION     NM_029510.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6959)
  AUTHORS   Takano,J., Ito,S., Dong,Y., Sharif,J., Nakajima-Takagi,Y.,
            Umeyama,T., Han,Y.W., Isono,K., Kondo,T., Iizuka,Y., Miyai,T.,
            Koseki,Y., Ikegaya,M., Sakihara,M., Nakayama,M., Ohara,O.,
            Hasegawa,Y., Hashimoto,K., Arner,E., Klose,R.J., Iwama,A.,
            Koseki,H. and Ikawa,T.
  TITLE     PCGF1-PRC1 links chromatin repression with DNA replication during
            hematopoietic cell lineage commitment
  JOURNAL   Nat Commun 13 (1), 7159 (2022)
   PUBMED   36443290
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6959)
  AUTHORS   Langouet,M., Jolicoeur,C., Javed,A., Mattar,P., Gearhart,M.D.,
            Daiger,S.P., Bertelsen,M., Tranebjaerg,L., Rendtorff,N.D.,
            Gronskov,K., Jespersgaard,C., Chen,R., Sun,Z., Li,H., Alirezaie,N.,
            Majewski,J., Bardwell,V.J., Sui,R., Koenekoop,R.K. and Cayouette,M.
  TITLE     Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with
            early-onset retinal degeneration
  JOURNAL   Sci Adv 8 (36), eabh2868 (2022)
   PUBMED   36070393
REFERENCE   3  (bases 1 to 6959)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6959)
  AUTHORS   Sportoletti,P., Sorcini,D., Guzman,A.G., Reyes,J.M., Stella,A.,
            Marra,A., Sartori,S., Brunetti,L., Rossi,R., Papa,B.D., Adamo,F.M.,
            Pianigiani,G., Betti,C., Scialdone,A., Guarente,V., Spinozzi,G.,
            Tini,V., Martelli,M.P., Goodell,M.A. and Falini,B.
  TITLE     Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates
            with Dnmt3a loss in acute erythroid leukemia onset in mice
  JOURNAL   Leukemia 35 (7), 1949-1963 (2021)
   PUBMED   33159179
  REMARK    GeneRIF: Bcor deficiency perturbs erythro-megakaryopoiesis and
            cooperates with Dnmt3a loss in acute erythroid leukemia onset in
            mice.
REFERENCE   5  (bases 1 to 6959)
  AUTHORS   Schmidt,C.R., Achille,N.J., Kuntimaddi,A., Boulton,A.M.,
            Leach,B.I., Zhang,S., Zeleznik-Le,N.J. and Bushweller,J.H.
  TITLE     BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1,
            SIX, and MYC Activity
  JOURNAL   Blood Cancer Discov 1 (2), 162-177 (2020)
   PUBMED   32954361
  REMARK    GeneRIF: BCOR Binding to MLL-AF9 Is Essential for Leukemia via
            Altered EYA1, SIX, and MYC Activity.
REFERENCE   6  (bases 1 to 6959)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (bases 1 to 6959)
  AUTHORS   Srinivasan,R.S., de Erkenez,A.C. and Hemenway,C.S.
  TITLE     The mixed lineage leukemia fusion partner AF9 binds specific
            isoforms of the BCL-6 corepressor
  JOURNAL   Oncogene 22 (22), 3395-3406 (2003)
   PUBMED   12776190
REFERENCE   8  (bases 1 to 6959)
  AUTHORS   Tomsig,J.L., Snyder,S.L. and Creutz,C.E.
  TITLE     Identification of targets for calcium signaling through the copine
            family of proteins. Characterization of a coiled-coil
            copine-binding motif
  JOURNAL   J Biol Chem 278 (12), 10048-10054 (2003)
   PUBMED   12522145
REFERENCE   9  (bases 1 to 6959)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 6959)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK053309.1, BC058656.1 and CD563463.1.
            
            On Dec 1, 2009 this sequence version replaced NM_029510.2.
            
            Transcript Variant: This variant (a) encodes the longest isoform
            (a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY161170.1, SRR9219380.80031.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-499               AK053309.1         2-500
            500-4286            BC058656.1         1-3787
            4287-4651           CD563463.1         83-447
            4652-6959           BC058656.1         4051-6358
FEATURES             Location/Qualifiers
     source          1..6959
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 6.83 cM"
     gene            1..6959
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /note="BCL6 interacting corepressor"
                     /db_xref="GeneID:71458"
                     /db_xref="MGI:MGI:1918708"
     exon            1..736
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            737..861
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     CDS             776..6055
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /note="isoform a is encoded by transcript variant a; BCL-6
                     corepressor"
                     /codon_start=1
                     /product="BCL-6 corepressor isoform a"
                     /protein_id="NP_083786.2"
                     /db_xref="CCDS:CCDS40873.1"
                     /db_xref="GeneID:71458"
                     /db_xref="MGI:MGI:1918708"
                     /translation="MLSATPLYGNVHSWMNSERVRMCGTSEDRKIPVNDGDASKARLE
                     LREETPLSHSVVDTSGAHRIDGLAALSMDRTGLIREGLRVPGNIVYSGLCGLGSEKGR
                     EATPSSLSGLGFSSERNPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAV
                     ATAESLGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMY
                     KALLPQQSYGLAQPLYSPVCTSGERFLYLPPPHYVNPHIPSSLASPMRLSTPSASAAI
                     PPLVHCSDKSLPWKMGVNPGNPVDSHSYPHIQNSKQPRVTSAKAVNSGLPGDTALLLP
                     PSPRPSARVHLPTQPAAETYSEFHKHYPRISTSPSVTLTKPYMTANSEFSTSRLSNGK
                     YPKALDGGDCAQSMPGHTRKTTVQDRKDGGSPPLLEKQTVTKDVTDKPLDLSSKVVDA
                     DASKGDHMKKMAPTVLVHSRAASGLVLSGSEIPKETLSPPGNGCSIYRSEIISTAPSS
                     WVVPGPSPNEENNGKSLSLKNKALDWAIPQQRSSSCPRMGGTDAVVTNVSGSVSSSGR
                     PASASPAPNANANADGTKTSRSSVDTTPSVIQHVGQPSSTPAKHGGSTSSKGAKANPE
                     PSFKASENGLPPTSIFLSPNEAFRSPAIPYPRSYLPYAAPEGIALSPLSLHGKGPVYP
                     HPVLLPNGSLFPGHLAPKPGLPYGLHTSRPEFVTYQDALGLGMVHPMLIPHTPIEITK
                     EEKPERRSRSHERARYEDPTLRSRFSEMLEASSTKLHPEVPTDKNLKPNSSWNQGKTG
                     VKSDKLVYVDLLREEADTKTDAGAPKAGLVAENVGQDTEATKPSADPVIQQRREFISL
                     REELGRITDFHESFTFKQASSQPVFSLGKDSGAAGTNKENLGVQVATPFLETALGSEG
                     PAVTFGKTQEDPKPFCVGGAPPNMDVTPAYTKEGTDEAESNDGKVLKPKPSKLAKRIA
                     NSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAMMRFSE
                     LEMKEREGSHPATKDSEVCKFSPADWERLKGNQEKKPKSVTLEEAIADQNDSERCEYS
                     TGNKHDLFEAPEDKDLPVEKYFLERPPVSEPPSDQGVVDTPHSPTLRLDRKRKLSGDS
                     THTETAVEELAEDPLKAKRRRISKDDWPEREMTNSSSNHLEDPHCNELTNLKVCIELT
                     GLHPKKQRHLLHLRERWEQQVSAAESKPGRQSRKEVAQAVQPEVTSQGTNITEEKPGR
                     KKAEAKGNRGWSEESLKSCDNEQGLPVLSGSPPMKSLSSTNASGKKQTQPSCTPASRL
                     PAKQQKIKESQKTDVLCTGEDEDCQAASPLQKYTDNIEKPSGKRLCKTKHLIPQESRR
                     SLQITGDYYVENTDTKMTVRRFRKRPEPSSDYDLSPPAKQEPKPFDRLQQLLPATQAT
                     QLPRSNSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKVCDV
                     NHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRL
                     LLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRSEDDTSGAWEFYGSSVC
                     EPDDESGYDVLANPPGPEDPDEEEDTYSDLFEFEFAESSLLPCYNIQVSVAQGPRNWL
                     LLSDVLKKLKMSSRIFRSNFPNLEIVTIAEAEFYRQVSTSLLFSCPKDLEAFNPESKE
                     LLDLVEFTNELQTLLGSSVEWLHPSDTGHENYW"
     exon            862..940
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            941..3787
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            3788..3841
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            3842..4028
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            4029..4286
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            4287..4631
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            4632..4957
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            4958..5215
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            5216..5382
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            5383..5528
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            5529..5606
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            5607..5763
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     exon            5764..6944
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6918..6923
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /note="hexamer: AATAAA"
     polyA_site      6939
                     /gene="Bcor"
                     /gene_synonym="2900008C10Rik; 5830466J11Rik;
                     8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575"
                     /note="major polyA site"
ORIGIN      
        1 agacggagcc tgagctccca gcggcaaggt gaggcagagc tgcgctccgg gccgaacggc
       61 gaccgagctc ttcggccgag ggggagacgc gccggaaccc agagcacgac cgagagcggg
      121 agcgaggcgg gcggcggtgg cggaggggga gcacgcgagc cgccgggcgg agagcccgag
      181 ccgcgctgtc gccgcggagg gacgacttgg ccaacacact cgctcacaca cactcacaca
      241 cacacccagc ccgagcgggc gctctcggcg aaccgtcaac atggcgctgg ggctcttgcc
      301 cgagcgcggg cggcagcggc ggcgcgggag ctgctgaggg tgacagagct cgggccagct
      361 gcgggaggag aggatcgcgc ggggccgtcg ccacctgccc tgaagctcgc agcccgcccc
      421 gccccgcccc acccccacgc ggcccagagc ccacccctcc gccgggccga ccccgagggc
      481 agcagagcgg ctgcagtcgg cggcgagcga gcgcggcgct gggagtggac tgcgggcacc
      541 agaggaagcc aaactttgct gctcgctgcg ctttcccggc cgggctcctt cacgtagccg
      601 ccctctcccg accccgcaca cattcaccca gccagccgcc cccggatctt cctcgccgcc
      661 tggactccgc tccggggaaa acttcaaagc gccggatcgc agggctccct gcctacttcc
      721 cgactgggga tttcagacta gacgcttgaa gccaagctgc catccaaggg gcgacatgct
      781 ttctgcaacc cctctgtatg ggaacgttca cagctggatg aacagcgaga gggtccgcat
      841 gtgtggaaca agtgaagaca ggaaaattcc tgtgaatgat ggcgacgctt caaaagccag
      901 gctggagctg agggaggaga ctcccctgag tcacagcgtg gtggatacca gtggagccca
      961 tcggatcgat ggcctggcag cactgagcat ggaccgcaca ggcctcatcc gggaagggct
     1021 ccgggtccct ggaaacatcg tttattctgg cttgtgtgga ttgggctcag aaaaaggtcg
     1081 ggaggctacc ccaagctctc tcagtggcct tgggttttct tcggaaagaa atccagagat
     1141 gcaattcaaa ccgaatactc ccgagacagt ggaggcttct gctgtctctg gaaaaccccc
     1201 aaatggcttc agtgctatat acaaaacacc gcctgggata caaaagagcg ctgtagctac
     1261 agcggaaagc ttgggtttgg ataggcctgc cagtgacaaa cagagccctc tcaacatcaa
     1321 tggtgctagt tacctgcggc tgccctgggt caacccttac atggaggggg ccactccagc
     1381 catataccct ttcctcgact cgccaaataa gtattcactg aatatgtaca aggccttgct
     1441 acctcagcag tcctacggct tggcccagcc actgtattct cctgtctgca ccagtgggga
     1501 acgcttcctc tacctgccac ccccacacta tgtcaaccct cacatcccct cctccttggc
     1561 ttcacccatg aggctctcca caccttcagc ctctgcggcc attccacctc tcgtccactg
     1621 ctcagacaaa agcctcccat ggaagatggg cgtcaaccct gggaacccag tagattccca
     1681 cagttacccc cacatccaaa acagtaaaca gccccgggtg acctctgcca aggcagtcaa
     1741 tagtggcctg ccaggggaca cagctctcct gttgcctcct tcacctcggc cctcagcccg
     1801 ggtccacctt ccaactcagc ccgctgcaga gacctactcc gagttccaca agcactatcc
     1861 caggatctcc acctctccct cagtcaccct gacgaagcca tacatgacag ccaatagcga
     1921 gttctctaca tccaggctgt ccaatggcaa gtaccccaag gctctagatg ggggcgactg
     1981 tgctcaatcc atgcctgggc acacccggaa gacaacggtt caagacagaa aagatggggg
     2041 ctcaccacct ctgttggaaa agcagaccgt taccaaagat gtcacagaca aaccacttga
     2101 cctgtcttct aaagtggtgg atgcggacgc ttccaaaggt gaccacatga aaaagatggc
     2161 tcccacagtc ctggttcaca gtcgggctgc aagtggctta gtgctctctg gaagtgagat
     2221 tccgaaagaa acactatctc ctccaggaaa tggatgttct atctatagat cagagatcat
     2281 cagcactgct ccctcatcct gggtggtgcc agggccaagt cctaatgaag agaacaatgg
     2341 caaaagtctg tcactgaaaa acaaggcttt ggactgggca ataccgcaac agcggagttc
     2401 ctcgtgtccc cgcatgggtg gcacagatgc cgtggtcact aatgtttcag ggtccgtgtc
     2461 cagctcagga cgcccagcct ctgcatcacc agcccccaac gccaacgcca atgcagatgg
     2521 caccaagacc agcaggagct cggtggatac cacgccatca gtcatccagc atgtgggcca
     2581 gccctcatcc acgcctgcca agcacggtgg cagcaccagc agcaagggag ccaaagccaa
     2641 cccagaaccg agcttcaaag cgagtgagaa tggcctcccg ccaacctcaa tatttctatc
     2701 tccaaatgaa gcattcaggt ccccagcaat tccctaccct aggagttacc tcccttacgc
     2761 agcaccagaa ggcatcgctc taagtcccct ctctttacat ggcaaaggac ctgtgtatcc
     2821 tcacccagtt ttgttaccca atggcagtct gtttcctggg caccttgccc caaagcctgg
     2881 cctgccttac gggctgcata cgagcaggcc agaatttgtg acctaccaag atgccctggg
     2941 cctgggcatg gtccatccca tgttgatccc acacacgccc attgagatca caaaagagga
     3001 gaagccggag agacgctccc gctcccatga gagagcccgt tatgaggacc caaccctccg
     3061 tagccggttt tctgagatgt tggaagctag cagcaccaaa ctgcatccag aagtccccac
     3121 tgacaagaac ctgaagccaa actctagctg gaatcaaggg aagactgggg tcaaaagcga
     3181 caaactggtc tacgtagacc ttctccgaga agaagcagac actaaaactg atgcaggggc
     3241 acccaaagca ggccttgtag ccgagaatgt aggtcaggac accgaggcca ccaagccctc
     3301 agctgaccct gtgatccaac aacgccgtga attcatctcc ctcagagagg agctgggccg
     3361 aatcactgac ttccatgaat ctttcacttt caaacaggcc tcaagccagc cagtgttcag
     3421 cttaggcaag gatagtggtg cagcaggaac caacaaagag aacctgggtg tgcaggtagc
     3481 aactccattc ttggagacag ctctgggcag tgagggccct gctgtgactt ttggtaaaac
     3541 ccaagaggat cccaaaccat tttgtgtggg cggtgcccct ccaaacatgg atgtcacccc
     3601 cgcctatacc aaagaaggaa ctgatgaggc cgaatccaac gatggcaaag ttctgaaacc
     3661 caagccatcc aagctggcaa agagaattgc taactcggca ggttatgtgg gcgaccgatt
     3721 caagtgtgtc accaccgaac tgtatgcaga ttccagtcag ctcagccgag agcagcgggc
     3781 attgcagatg gaaggattac aagaggacag tattttatgt ctacccgctg cttactgtga
     3841 gcgtgcaatg atgcgcttct cagagttgga gatgaaagag agagaaggta gccacccagc
     3901 aaccaaagac tccgaggtgt gcaaattcag cccagccgac tgggaaaggt tgaaaggaaa
     3961 tcaggaaaag aagccaaagt cagtcaccct ggaagaggcc attgccgacc agaatgacag
     4021 tgagagatgt gagtatagca ctggaaacaa acatgatctc tttgaagccc cagaggacaa
     4081 agatcttcct gtggaaaagt atttcttgga gaggccacct gtgagtgagc cacccagtga
     4141 ccagggggtg gtggacacgc cacacagccc caccctccgg ctagacagga aacgcaaact
     4201 gtcaggtgac agcacccaca ctgagaccgc tgtggaagag ctagctgagg accctctgaa
     4261 agccaagcga agacggatct ccaaagatga ctggcctgag agggaaatga caaacagttc
     4321 ctctaaccac ttagaagacc cacattgtaa tgagctgacc aacctgaagg tgtgcattga
     4381 attaacaggg ctccatccta aaaagcaacg ccacttgctg caccttagag aacggtggga
     4441 gcagcaggtg tcggcagccg agagcaaacc tggccggcaa agcaggaagg aagtggccca
     4501 ggctgttcag cctgaggtca cctcccaggg gactaacatc actgaagaga agcctggcag
     4561 gaaaaaggca gaggccaaag gcaacagagg ctggtctgaa gagtcgctca aatcctgtga
     4621 caatgagcaa ggcttgcctg tgctctcagg ctctccgccc atgaagagcc tttcatccac
     4681 caatgcaagt ggcaaaaagc agactcagcc aagctgcacg ccagcctcaa ggctgcctgc
     4741 caaacagcag aaaattaaag aaagccagaa gacagatgtg ctgtgcacag gggaagacga
     4801 ggattgccag gctgcctccc cgctgcaaaa atacacagac aacatcgaga agccatccgg
     4861 gaagagactg tgcaaaacca agcacttgat acctcaggag tccaggagga gcttgcagat
     4921 cacaggcgac tactatgtgg agaacactga cactaagatg actgtgcgga gattcagaaa
     4981 acgacctgag cccagttcgg actacgattt gtcaccacca gccaagcagg agccaaagcc
     5041 ctttgaccgt ctacaacaat tgctaccggc cacccaggcc acccagctgc cacgctcaaa
     5101 ttctcctcaa gagaccaccc agtctcgccc catgccgcca gaagctcgga gacttattgt
     5161 caataagaat gctggcgaga ccctcctgca gcgggctgcc cggctaggct atgaggaagt
     5221 ggtcttatat tgcctggaga acaaggtctg tgatgtcaat catcgagaca atgctggcta
     5281 ctgtgctctg catgaagctt gcgccagggg atggctcaac atcgtgcgcc acctccttga
     5341 atatggcgct gatgtcaact gcagtgccca ggatggaacc aggcctctgc atgatgctgt
     5401 ggagaatgac cacttagaaa ttgtacgatt gcttctttcc tatggtgctg accctacttt
     5461 ggccacatac tcagggagaa ccatcatgaa aatgacccac agtgaactta tggagaagtt
     5521 tttaacagac tatttaaatg acctgcaggg tcgcagtgaa gatgacacca gcggcgcttg
     5581 ggagttctat ggcagctctg tgtgtgaacc agatgacgaa agtgggtacg atgttttggc
     5641 taatccccca ggaccagaag acccagatga ggaagaggat acctatagcg atttgtttga
     5701 gtttgagttt gctgaaagct ccctcttgcc gtgttataac atccaagtgt ctgtcgctca
     5761 ggggccacga aactggcttc tgctctcaga cgtgctcaag aagttgaaaa tgtcctcccg
     5821 gatattccgt agcaattttc ccaatctgga aattgtcacc attgcagagg cggagtttta
     5881 ccgacaggtc tcaacaagtc tcttgttctc ctgccccaaa gacctggaag ccttcaatcc
     5941 tgaaagcaag gagctgttgg atctggtgga attcaccaat gagctccaga cactgctggg
     6001 ctcctctgtg gagtggctcc accctagtga cacgggccat gaaaactact ggtgagccac
     6061 ctgccccgcc cacccactgt gtacagtgtg ttatagtgtt aatccttgtg catatgtgtc
     6121 ataatacaac aatttctgta aagaaaggac actattacat atgaaaatat ctcttcttta
     6181 tataagagaa gttactccgg tcagaagaac ccagaagccc gtgttttctt tctaaaattt
     6241 taagtcagtt tttatgaagc tgttgaaatg tctttatttt tcagtgtaca catgctttga
     6301 aatgtatgtt cgtttttact tggaacattt ttcttttctg ttcttttcta aggagaaaaa
     6361 aataaatgaa taaatgaata aatgaaaagg agctctgtgc ttggcgtaat ttcatacaaa
     6421 gctctggtgg cgggccatgg gtgtattgtg tggtgaggac tatgtgtttg gtttgctgga
     6481 gtgaattggg tgaaggcact tggtggtggt atacttttat gttttgttta cagagtacct
     6541 gctcacacca ggtaaatgct attggacgtg atccagtggt atgtaatata aattcaaacc
     6601 atatccacac acaacaacta attgtaagaa acttttgtat cctaatttaa aagctgtgaa
     6661 attacttttc acacatcaaa ccggattgtt tatatgttta aacattttat gctcttattt
     6721 aaagaagact ttgagctatt tttttctgta ctctgtaaaa tattgaaaac taacataata
     6781 tgttgaggtt gcttgaaaat gtacataaaa ctaaaatttt ctgaattgtg tgtttatgtt
     6841 tgaaatctgt gttttaactt tgtaagtaaa ttctctgcct ttgtatttat attttacaaa
     6901 aatttttctt aaaaggcaat aaacctgttg aggaaaggag caaaaaaaaa aaaaaaaaa
//
