LOCUS       NM_001142959             760 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus BCLl2-like 15 (Bcl2l15), transcript variant 1, mRNA.
ACCESSION   NM_001142959
VERSION     NM_001142959.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 760)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 760)
  AUTHORS   Pujianto,D.A., Damdimopoulos,A.E., Sipila,P., Jalkanen,J.,
            Huhtaniemi,I. and Poutanen,M.
  TITLE     Bfk, a novel member of the bcl2 gene family, is highly expressed in
            principal cells of the mouse epididymis and demonstrates a
            predominant nuclear localization
  JOURNAL   Endocrinology 148 (7), 3196-3204 (2007)
   PUBMED   17412810
REFERENCE   3  (bases 1 to 760)
  AUTHORS   Zhang,Q.Y., Clausen,P.A., Yatsula,B.A., Calothy,G. and Blair,D.G.
  TITLE     Mutation of polyadenylation signals generates murine retroviruses
            that produce fused virus-cell RNA transcripts at high frequency
  JOURNAL   Virology 241 (1), 80-93 (1998)
   PUBMED   9454719
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC117780.1, BC052523.1 and BC027668.1.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript and encodes the shorter isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC117780.1, AF014453.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               BC117780.1         1-122
            123-123             BC052523.1         57-57
            124-710             BC117780.1         124-710
            711-760             BC027668.1         547-596
FEATURES             Location/Qualifiers
     source          1..760
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 45.52 cM"
     gene            1..760
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /note="BCLl2-like 15"
                     /db_xref="GeneID:229672"
                     /db_xref="MGI:MGI:2685412"
     exon            1..272
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..640
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /note="isoform 1 is encoded by transcript variant 1;
                     bcl-2-like protein 15; bcl2-L-15; Bcl2-like 15; bcl-2
                     family kin"
                     /codon_start=1
                     /product="bcl-2-like protein 15 isoform 1"
                     /protein_id="NP_001136431.1"
                     /db_xref="CCDS:CCDS51027.1"
                     /db_xref="GeneID:229672"
                     /db_xref="MGI:MGI:2685412"
                     /translation="MSKMKNPRTFEEQTECIVNSLLKDFRTPLSHAANRNLSGADEPC
                     SGEDYSFDVAIIVGRLRILGDQFNGELEASANNIIAVTIGGQAGSTVLNDTVQSLSRT
                     WCTQDPTLVFERAFLAVSVKLLEYVVRKAPNVARQVANYVTGMINGNTAIREFIQGQG
                     GWENLES"
     exon            273..394
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /inference="alignment:Splign:2.1.0"
     exon            395..622
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /inference="alignment:Splign:2.1.0"
     exon            623..738
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /inference="alignment:Splign:2.1.0"
     regulatory      714..719
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /note="hexamer: ATTAAA"
     polyA_site      738
                     /gene="Bcl2l15"
                     /gene_synonym="Bfk; Gm566"
                     /note="major polyA site"
ORIGIN      
        1 tcatcccctt tgagcagttt catttggaaa gttaatggga actattttag gacatatcca
       61 attaggaagc aataagaggt aggcagccac aactggtttg ccaggttctc taacttcctg
      121 ctaagctttg tggagaatgt ctaaaatgaa aaaccctcgg acttttgagg agcaaacaga
      181 atgcatcgtg aattctctac tcaaagactt caggacccca ctatcccacg ctgctaaccg
      241 gaacctatcg ggtgcagatg aaccatgctc aggagaggat tactcttttg atgtggctat
      301 cattgttggc cgccttcgaa tactgggtga tcagttcaat ggagagctgg aagcttctgc
      361 caataatatc attgcggtaa ccattggagg acaggcagga agtactgtac tcaacgacac
      421 agtacagtct ctcagcagaa cctggtgcac tcaggatcct actttagttt ttgaacgagc
      481 ctttttggca gtatcagtaa aacttcttga atatgtggtc cgtaaggctc caaacgtggc
      541 aagacaggtg gctaactacg tgacgggcat gatcaacggg aacacagcca tccgcgagtt
      601 tatccagggc cagggaggat gggaaaacct ggagagctga agaagaggat tattctaacc
      661 cagactgagc atcacgtcct ctgacagatt gggtgggcga ttgatttctg acaattaaaa
      721 cattctgttt tcaattcaaa aaaaaaaaaa aaaaaaaaaa
//
