LOCUS       NM_009742                796 bp    mRNA    linear   ROD 24-DEC-2024
DEFINITION  Mus musculus B cell leukemia/lymphoma 2 related protein A1a
            (Bcl2a1a), mRNA.
ACCESSION   NM_009742
VERSION     NM_009742.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Vier,J., Hacker,G. and Kirschnek,S.
  TITLE     Contribution of A1 to macrophage survival in cooperation with MCL-1
            and BCL-XL in a murine cell model of myeloid differentiation
  JOURNAL   Cell Death Dis 15 (9), 677 (2024)
   PUBMED   39285161
  REMARK    GeneRIF: Contribution of A1 to macrophage survival in cooperation
            with MCL-1 and BCL-XL in a murine cell model of myeloid
            differentiation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  AUTHORS   Soma,S., Murakami,K., Fukuchi,Y., Kunimoto,H. and Nakajima,H.
  TITLE     O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse
            Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL
            and Oxidative Phosphorylation
  JOURNAL   Stem Cells 42 (1), 55-63 (2024)
   PUBMED   37813816
REFERENCE   3  (bases 1 to 796)
  AUTHORS   Saito,A., Murata,H., Niitani,K., Nagasaki,J., Otoda,A., Chujo,Y.,
            Yanagida,J., Nishitani,N., Deyama,S. and Kaneda,K.
  TITLE     Social defeat stress enhances the rewarding effects of cocaine
            through alpha1A adrenoceptors in the medial prefrontal cortex of
            mice
  JOURNAL   Neuropharmacology 242, 109757 (2024)
   PUBMED   37839511
  REMARK    GeneRIF: Social defeat stress enhances the rewarding effects of
            cocaine through alpha1A adrenoceptors in the medial prefrontal
            cortex of mice.
REFERENCE   4  (bases 1 to 796)
  AUTHORS   Schenk,R.L., Gangoda,L., Lawlor,K.E., O'Reilly,L.A., Strasser,A.
            and Herold,M.J.
  TITLE     The pro-survival Bcl-2 family member A1 delays spontaneous and FAS
            ligand-induced apoptosis of activated neutrophils
  JOURNAL   Cell Death Dis 11 (6), 474 (2020)
   PUBMED   32555150
  REMARK    GeneRIF: The pro-survival Bcl-2 family member A1 delays spontaneous
            and FAS ligand-induced apoptosis of activated neutrophils.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 796)
  AUTHORS   Tan,L., Sandrock,I., Odak,I., Aizenbud,Y., Wilharm,A.,
            Barros-Martins,J., Tabib,Y., Borchers,A., Amado,T., Gangoda,L.,
            Herold,M.J., Schmidt-Supprian,M., Kisielow,J., Silva-Santos,B.,
            Koenecke,C., Hovav,A.H., Krebs,C., Prinz,I. and Ravens,S.
  TITLE     Single-Cell Transcriptomics Identifies the Adaptation of Scart1+
            Vgamma6+ T Cells to Skin Residency as Activated Effector Cells
  JOURNAL   Cell Rep 27 (12), 3657-3671 (2019)
   PUBMED   31216482
REFERENCE   6  (bases 1 to 796)
  AUTHORS   Karsan,A., Yee,E., Kaushansky,K. and Harlan,J.M.
  TITLE     Cloning of human Bcl-2 homologue: inflammatory cytokines induce
            human A1 in cultured endothelial cells
  JOURNAL   Blood 87 (8), 3089-3096 (1996)
   PUBMED   8605321
REFERENCE   7  (bases 1 to 796)
  AUTHORS   Choi,M.S., Holmann,M., Atkins,C.J. and Klaus,G.G.
  TITLE     Expression of bcl-x during mouse B cell differentiation and
            following activation by various stimuli
  JOURNAL   Eur J Immunol 26 (3), 676-682 (1996)
   PUBMED   8605937
REFERENCE   8  (bases 1 to 796)
  AUTHORS   Evans,D.L. and Mansel,R.E.
  TITLE     Molecular evolution and secondary structural conservation in the
            B-cell lymphoma leukemia 2 (bcl-2) family of proto-oncogene
            products
  JOURNAL   J Mol Evol 41 (6), 775-783 (1995)
   PUBMED   8587122
REFERENCE   9  (bases 1 to 796)
  AUTHORS   Choi,S.S., Park,I.C., Yun,J.W., Sung,Y.C., Hong,S.I. and Shin,H.S.
  TITLE     A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach
            cancer and preferentially expressed in bone marrow
  JOURNAL   Oncogene 11 (9), 1693-1698 (1995)
   PUBMED   7478596
REFERENCE   10 (bases 1 to 796)
  AUTHORS   Lin,E.Y., Orlofsky,A., Berger,M.S. and Prystowsky,M.B.
  TITLE     Characterization of A1, a novel hemopoietic-specific early-response
            gene with sequence similarity to bcl-2
  JOURNAL   J Immunol 151 (4), 1979-1988 (1993)
   PUBMED   8345191
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT030259.6.
            
            On Nov 17, 2006 this sequence version replaced NM_009742.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L16462.1, BY548861.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-551               CT030259.6         114033-114583
            552-796             CT030259.6         119285-119529
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 47.24 cM"
     gene            1..796
                     /gene="Bcl2a1a"
                     /gene_synonym="A1; Bcl2a1; Bfl-1; Hbpa1"
                     /note="B cell leukemia/lymphoma 2 related protein A1a"
                     /db_xref="GeneID:12044"
                     /db_xref="MGI:MGI:102687"
     exon            1..551
                     /gene="Bcl2a1a"
                     /gene_synonym="A1; Bcl2a1; Bfl-1; Hbpa1"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..650
                     /gene="Bcl2a1a"
                     /gene_synonym="A1; Bcl2a1; Bfl-1; Hbpa1"
                     /note="A1-A; protein BFL-1; hemopoietic-specific early
                     response protein"
                     /codon_start=1
                     /product="bcl-2-related protein A1"
                     /protein_id="NP_033872.1"
                     /db_xref="CCDS:CCDS23391.1"
                     /db_xref="GeneID:12044"
                     /db_xref="MGI:MGI:102687"
                     /translation="MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSV
                     QKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKK
                     LPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQM
                     TGQIWEMLFLLK"
     exon            552..796
                     /gene="Bcl2a1a"
                     /gene_synonym="A1; Bcl2a1; Bfl-1; Hbpa1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacatgatgc aaacagaaat tccaacagcc tccagatatg attagggttc ctcccctgac
       61 aagacctatc tttgcagtct ttgcctcctt ggcctctagg tggacagctg cagtcagctc
      121 tgccagggaa gatggctgag tctgagctca tgcatatcca ctccctggct gagcactacc
      181 ttcagtatgt gctacaggta cccgcctttg agtcggctcc aagccaagca tgcagagtgc
      241 tacaaagagt tgctttctcc gttcagaagg aagttgaaaa gaatctgaag tcatacttgg
      301 atgactttca cgtggaatcc atagataccg ccagaataat attcaaccaa gtgatggaaa
      361 aagagtttga agatggcatc attaactggg gaaggattgt gactatattt gcctttgggg
      421 gtgttctcct caaaaaactt ccacaagagc agattgccct ggatgtatgt gcttacaaac
      481 aagtttccag ttttgtggca gaattcataa tgaataacac aggagaatgg atacggcaga
      541 atggaggttg ggaagatggc ttcataaaga agtttgaacc caaatctggc tggctgactt
      601 ttctgcagat gacaggacag atctgggaaa tgctctttct cctcaagtaa cactacggac
      661 cagagagaac cttggctccc acgagaatgg ttatcagcac ttggcatttc cttttacaaa
      721 catgaaactt gtctttccag agttgcagat attttgtttc aactttaatg aataaattac
      781 tagtatttgt ttctgt
//
