LOCUS       NM_001313698            1329 bp    mRNA    linear   ROD 21-NOV-2023
DEFINITION  Mus musculus B cell receptor associated protein 31 (Bcap31),
            transcript variant 2, mRNA.
ACCESSION   NM_001313698
VERSION     NM_001313698.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1329)
  AUTHORS   Zhao B, Sun L, Yuan Q, Hao Z, An F, Zhang W, Zhu X and Wang B.
  TITLE     BAP31 Knockout in Macrophages Affects CD4+T Cell Activation through
            Upregulation of MHC Class II Molecule
  JOURNAL   Int J Mol Sci 24 (17), 13476 (2023)
   PUBMED   37686286
  REMARK    GeneRIF: BAP31 Knockout in Macrophages Affects CD4[+]T Cell
            Activation through Upregulation of MHC Class II Molecule.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1329)
  AUTHORS   Wei X, Li L, Zhao J, Huo Y, Hu X, Lu J, Pi J, Zhang W, Xu L, Yao Y
            and Xu J.
  TITLE     BAP31 depletion inhibited adipogenesis, repressed lipolysis and
            promoted lipid droplets abnormal growth via attenuating Perilipin1
            proteasomal degradation
  JOURNAL   Int J Biol Sci 19 (6), 1713-1730 (2023)
   PUBMED   37063427
  REMARK    GeneRIF: BAP31 depletion inhibited adipogenesis, repressed
            lipolysis and promoted lipid droplets abnormal growth via
            attenuating Perilipin1 proteasomal degradation.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1329)
  AUTHORS   Li G, Jiang X, Liang X, Hou Y, Zang J, Zhu B, Jia C, Niu K, Liu X,
            Xu X, Jiang R and Wang B.
  TITLE     BAP31 regulates the expression of ICAM-1/VCAM-1 via MyD88/NF-kappaB
            pathway in acute lung injury mice model
  JOURNAL   Life Sci 313, 121310 (2023)
   PUBMED   36549351
  REMARK    GeneRIF: BAP31 regulates the expression of ICAM-1/VCAM-1 via
            MyD88/NF-kappaB pathway in acute lung injury mice model.
REFERENCE   4  (bases 1 to 1329)
  AUTHORS   Li GX, Jiang XH, Zang JN, Zhu BZ, Jia CC, Niu KW, Liu X, Jiang R
            and Wang B.
  TITLE     B-cell receptor associated protein 31 deficiency decreases the
            expression of adhesion molecule CD11b/CD18 and PSGL-1 in
            neutrophils to ameliorate acute lung injury
  JOURNAL   Int J Biochem Cell Biol 152, 106299 (2022)
   PUBMED   36210579
  REMARK    GeneRIF: B-cell receptor associated protein 31 deficiency decreases
            the expression of adhesion molecule CD11b/CD18 and PSGL-1 in
            neutrophils to ameliorate acute lung injury.
REFERENCE   5  (bases 1 to 1329)
  AUTHORS   Yuan Q, Zhao B, Cao YH, Yan JC, Sun LJ, Liu X, Xu Y, Wang XY and
            Wang B.
  TITLE     BCR-Associated Protein 31 Regulates Macrophages Polarization and
            Wound Healing Function via Early Growth Response 2/C/EBPbeta and
            IL-4Ralpha/C/EBPbeta Pathways
  JOURNAL   J Immunol 209 (6), 1059-1070 (2022)
   PUBMED   36002233
  REMARK    GeneRIF: BCR-Associated Protein 31 Regulates Macrophages
            Polarization and Wound Healing Function via Early Growth Response
            2/C/EBPbeta and IL-4Ralpha/C/EBPbeta Pathways.
REFERENCE   6  (bases 1 to 1329)
  AUTHORS   Pang AL, Taylor HC, Johnson W, Alexander S, Chen Y, Su YA, Li X,
            Ravindranath N, Dym M, Rennert OM and Chan WY.
  TITLE     Identification of differentially expressed genes in mouse
            spermatogenesis
  JOURNAL   J Androl 24 (6), 899-911 (2003)
   PUBMED   14581517
REFERENCE   7  (bases 1 to 1329)
  AUTHORS   Schamel WW, Kuppig S, Becker B, Gimborn K, Hauri HP and Reth M.
  TITLE     A high-molecular-weight complex of membrane proteins BAP29/BAP31 is
            involved in the retention of membrane-bound IgD in the endoplasmic
            reticulum
  JOURNAL   Proc Natl Acad Sci U S A 100 (17), 9861-9866 (2003)
   PUBMED   12886015
  REMARK    GeneRIF: A high-molecular-weight complex of membrane proteins
            BAP29/BAP31 is involved in the retention of membrane-bound IgD in
            the endoplasmic reticulum.
REFERENCE   8  (bases 1 to 1329)
  AUTHORS   Bell AW, Ward MA, Blackstock WP, Freeman HN, Choudhary JS, Lewis
            AP, Chotai D, Fazel A, Gushue JN, Paiement J, Palcy S, Chevet E,
            Lafreniere-Roula M, Solari R, Thomas DY, Rowley A and Bergeron JJ.
  TITLE     Proteomics characterization of abundant Golgi membrane proteins
  JOURNAL   J Biol Chem 276 (7), 5152-5165 (2001)
   PUBMED   11042173
REFERENCE   9  (bases 1 to 1329)
  AUTHORS   Adachi T, Schamel WW, Kim KM, Watanabe T, Becker B, Nielsen PJ and
            Reth M.
  TITLE     The specificity of association of the IgD molecule with the
            accessory proteins BAP31/BAP29 lies in the IgD transmembrane
            sequence
  JOURNAL   EMBO J 15 (7), 1534-1541 (1996)
   PUBMED   8612576
REFERENCE   10 (bases 1 to 1329)
  AUTHORS   Kim KM, Adachi T, Nielsen PJ, Terashima M, Lamers MC, Kohler G and
            Reth M.
  TITLE     Two new proteins preferentially associated with membrane
            immunoglobulin D
  JOURNAL   EMBO J 13 (16), 3793-3800 (1994)
   PUBMED   8070407
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX226458.1, AL805924.5, AK011500.1 and AI838720.1.
            
            [WARNING] On Dec 6, 2023 this sequence was replaced by
            NM_001313698.2.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 both encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422598.1047806.1,
                                           SRR13422600.439680.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               CX226458.1         1-101
            102-102             AL805924.5         204606-204606       c
            103-524             CX226458.1         103-524
            525-1291            AK011500.1         429-1195
            1292-1329           AI838720.1         1-38                c
FEATURES             Location/Qualifiers
     source          1..1329
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 37.38 cM"
     gene            1..1329
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /note="B cell receptor associated protein 31"
                     /db_xref="GeneID:27061"
                     /db_xref="MGI:MGI:1350933"
     exon            1..155
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
     exon            156..291
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
     CDS             200..937
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /note="accessory protein BAP31; p28; BCR-associated
                     protein 31"
                     /codon_start=1
                     /product="B-cell receptor-associated protein 31"
                     /protein_id="NP_001300627.1"
                     /db_xref="CCDS:CCDS30209.1"
                     /db_xref="GeneID:27061"
                     /db_xref="MGI:MGI:1350933"
                     /translation="MSLQWTTVATFLYAEVFAVLLLCIPFISPKRWQKVFKSRLVELV
                     VTYGNTFFVVLIVILVLLVIDAVREILKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRN
                     LYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKG
                     AAEDGDKLDIGNTEMKLEENKSLKNDLRKLKDELASTKKKLEKAENEALAMQKQSEGL
                     TKEYDRLLEEHAKLQASVRGPSVKKEE"
     exon            292..392
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
     exon            393..540
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
     exon            541..676
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
     exon            677..797
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
     exon            798..898
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1316
                     /gene="Bcap31"
                     /gene_synonym="Bap31"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaggctc gaagcacgtt ggctgtgagg aacaccacca ggccagcgat ggctgagggc
       61 caggctgtgc cagctcctcg ggatcgggca gctcgaagga gagtgtagga ggtcacagcc
      121 acatccagga gtggcttggt caggttggaa taaaggaaac aagctcccat ccctctgttg
      181 gaacccttta agtcacagga tgagtttgca gtggactaca gttgccacct tcctctacgc
      241 agaggtcttt gctgtgttgc ttctctgcat tcccttcatt tctccaaaaa gatggcagaa
      301 ggtttttaaa tcccggctgg tggagttggt agtgacctat ggcaacactt tctttgtggt
      361 tctcatcgtc atccttgtac tgttggttat tgatgctgta cgagagatcc tgaaatacga
      421 tgatgtgaca gaaaaggtga acctccagaa caatccaggt gccatggagc acttccacat
      481 gaagcttttc cgtgctcaga ggaatctcta tattgctggc ttttccttgc tgctgtcctt
      541 cctgcttaga cgcctggtga ctctcatctc ccagcaggcc acactgctgg cctccaatga
      601 agcctttaaa aagcaggcag aaagtgccag tgaggcggcc aagaaataca tggaggagaa
      661 tgatcagcta aagaagggag ctgccgagga tggagacaag ttggatattg ggaatactga
      721 aatgaagtta gaggagaaca agagcctgaa gaatgacctg aggaagctaa aagatgagct
      781 ggccagcacc aagaaaaaac ttgagaaagc tgaaaacgag gctctggcta tgcagaagca
      841 gtctgagggc cttaccaaag aatatgaccg cctgctagaa gaacatgcca aactgcaggc
      901 atcagtacgt ggtccctcag tcaagaagga ggagtaaagg cttggtgttt ccctgcctgc
      961 cgctggcttc tacctgaccc atgcttactg cttccttgga gcccagacta tccctctggt
     1021 acttgggttt attccctact tccccaattt tcttccatgg cttatagatc attattttgg
     1081 caccattaca catactgctc ttataccaaa agggacctga ttgttgttta ttcagagtac
     1141 ttttgccact gttctgcctg gctagggcac tttccactcc tggaagtgta gaaaagcact
     1201 ggtgacctgg cctgcagttt gaaccccttt ttattttgca atgtacccta aaggaggctg
     1261 ctgtgaagca ggtcaactgt tttatcctga ggggaataaa tgttgttatg ttataaaaaa
     1321 aaaaaaaaa
//
