LOCUS       NM_001164090            1791 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus B cell receptor associated protein 29 (Bcap29),
            transcript variant 2, mRNA.
ACCESSION   NM_001164090
VERSION     NM_001164090.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1791)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1791)
  AUTHORS   Gineste,C., De Winter,J.M., Kohl,C., Witt,C.C., Giannesini,B.,
            Brohm,K., Le Fur,Y., Gretz,N., Vilmen,C., Pecchi,E., Jubeau,M.,
            Cozzone,P.J., Stienen,G.J., Granzier,H., Labeit,S.,
            Ottenheijm,C.A., Bendahan,D. and Gondin,J.
  TITLE     In vivo and in vitro investigations of heterozygous nebulin
            knock-out mice disclose a mild skeletal muscle phenotype
  JOURNAL   Neuromuscul Disord 23 (4), 357-369 (2013)
   PUBMED   23375831
REFERENCE   3  (bases 1 to 1791)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   4  (bases 1 to 1791)
  AUTHORS   Paquet,M.E., Cohen-Doyle,M., Shore,G.C. and Williams,D.B.
  TITLE     Bap29/31 influences the intracellular traffic of MHC class I
            molecules
  JOURNAL   J Immunol 172 (12), 7548-7555 (2004)
   PUBMED   15187134
  REMARK    GeneRIF: results are consistent with the view that class I
            molecules are largely recruited to ER exit sites by Bap29/31, and
            that Bap29/31 is a cargo receptor for MHC class I molecules
REFERENCE   5  (bases 1 to 1791)
  AUTHORS   Schamel,W.W., Kuppig,S., Becker,B., Gimborn,K., Hauri,H.P. and
            Reth,M.
  TITLE     A high-molecular-weight complex of membrane proteins BAP29/BAP31 is
            involved in the retention of membrane-bound IgD in the endoplasmic
            reticulum
  JOURNAL   Proc Natl Acad Sci U S A 100 (17), 9861-9866 (2003)
   PUBMED   12886015
  REMARK    GeneRIF: A high-molecular-weight complex of membrane proteins
            BAP29/BAP31 is involved in the retention of membrane-bound IgD in
            the endoplasmic reticulum.
REFERENCE   6  (bases 1 to 1791)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 1791)
  AUTHORS   Kim,K.M., Adachi,T., Nielsen,P.J., Terashima,M., Lamers,M.C.,
            Kohler,G. and Reth,M.
  TITLE     Two new proteins preferentially associated with membrane
            immunoglobulin D
  JOURNAL   EMBO J 13 (16), 3793-3800 (1994)
   PUBMED   8070407
REFERENCE   8  (bases 1 to 1791)
  AUTHORS   Terashima,M., Kim,K.M., Adachi,T., Nielsen,P.J., Reth,M., Kohler,G.
            and Lamers,M.C.
  TITLE     The IgM antigen receptor of B lymphocytes is associated with
            prohibitin and a prohibitin-related protein
  JOURNAL   EMBO J 13 (16), 3782-3792 (1994)
   PUBMED   8070406
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC119950.14.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1 and 2 both encode the same
            protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090068.1, AK144754.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                AC119950.14        101875-101928       c
            55-172              AC119950.14        101533-101650       c
            173-273             AC119950.14        98063-98163         c
            274-424             AC119950.14        93996-94146         c
            425-560             AC119950.14        91385-91520         c
            561-666             AC119950.14        84345-84450         c
            667-767             AC119950.14        67914-68014         c
            768-1791            AC119950.14        62624-63647         c
FEATURES             Location/Qualifiers
     source          1..1791
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 13.63 cM"
     gene            1..1791
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /note="B cell receptor associated protein 29"
                     /db_xref="GeneID:12033"
                     /db_xref="MGI:MGI:101917"
     exon            1..54
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     exon            55..172
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..803
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /note="BCR-associated protein 29"
                     /codon_start=1
                     /product="B-cell receptor-associated protein 29"
                     /protein_id="NP_001157562.1"
                     /db_xref="CCDS:CCDS25864.1"
                     /db_xref="GeneID:12033"
                     /db_xref="MGI:MGI:101917"
                     /translation="MTIQWAAVASFLYAEIGLILLFCLPFIPPQRWQKIFSFSVWGKI
                     ASFWNKAFLTIIILLIILFLDAVREVRKYSSTNVVEKNSAIRPSAFEHTQMKLFRSQR
                     NLYISGFSLFFWLVLRRLVTLITQLAKEIANKGVLKIQAENTNKAAKKFMEENEKLKL
                     GLRNDNAEEHLLEAENKKLIESKENLKTELKKASDALLKAQNDVMTMKIQSERLSKEY
                     DRLLKEHSELQNRLEKEKKKGL"
     exon            173..273
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     exon            274..424
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     exon            425..560
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     exon            561..666
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     exon            667..767
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     exon            768..1791
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1770..1775
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /note="hexamer: TATAAA"
     regulatory      1775..1780
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /note="hexamer: AAGAAA"
     polyA_site      1788
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
     polyA_site      1791
                     /gene="Bcap29"
                     /gene_synonym="Bap29"
                     /note="major polyA site"
ORIGIN      
        1 gtgggacgtg cgcgcgcagg cgggcggcgg ggcacgcgga gcgatcggcg gcgggtgtga
       61 agaaaaaaca aaacaaaacg atgacaatcc aatgggcggc ggttgccagc tttctttatg
      121 ctgaaatagg actcatttta ctcttctgtc tgccctttat tcctccacag agatggcaga
      181 agattttttc atttagtgtc tggggtaaga ttgcaagttt ttggaacaaa gcttttctta
      241 ccattataat actattgatc attctgtttc tagatgccgt gagagaagta agaaagtatt
      301 cgtccacgaa tgttgtagag aagaactcag ccatcagacc gagtgccttt gagcacacac
      361 agatgaagct cttcaggtct caaagaaatc tgtatatttc tggattctca ttattttttt
      421 ggctagtgtt gagacgtctg gttacgctta ttactcagct ggcaaaagaa atagcaaaca
      481 aaggagtgct taaaattcaa gcagaaaata ccaataaggc tgccaagaaa ttcatggaag
      541 agaatgaaaa actaaaattg gggctaagaa atgacaatgc tgaagaacac cttttggaag
      601 ctgaaaataa aaaactaata gaaagcaagg agaacctgaa aaccgagctg aagaaggctt
      661 ccgatgccct tttgaaggcc caaaatgatg tcatgactat gaagattcag tcagagagac
      721 tttctaaaga gtatgaccga ctcctgaaag aacactcaga acttcagaac cgtttagaga
      781 aagagaagaa gaaaggcctg tgaactaact ttataaaaga agactgtaat acaccttgtc
      841 aaagttcagt tgaaaacaaa gaaagctgtg ctagcgcctg cagacccgca caggctatac
      901 agtagtgaca tttccaaaat atttgataat gtttcagatt tcagatataa agtatggatt
      961 tcagctcttt tggaaaatat aagcatgtta aataccatat ttacatattg ctaatagcat
     1021 tgatatatgg tggctcttta cccataaaag gaaattttca tttgctagca tttacttccc
     1081 aaattagatc tgaagttgca tgaaaccatt attagctttg aaagctttga tgtgttttta
     1141 gtaataatca gatgatggta gtggtaaaaa tgatgtgttt gaaaagagaa ctcagtatca
     1201 gaaaatgttt tcacagggaa acaaggatga gtaaccacaa ttagccactg cgcttatcga
     1261 gaagagtcag agaacagcga aaactacggc cttagggctc ttcaagcctc atgattgtac
     1321 aacctactcg aaatatgaca gcactgttga tagtgtgtgt tgctactgtg cttctgtgcc
     1381 tataagacta ttgataattt gtttagtcat atatggtcag tagtctgtct tttcaaggtc
     1441 atctgctaat agaatgtatg cccatttgca aaactgtcat accactgaac tgagcttatg
     1501 ttgcactgtg gatttctcca ctgacaaagc ttatttacga catcctaaaa gcagcgtttt
     1561 ttctatttgt gaaagttact gattgtactg gtattacctc agtattcatg cactggtatc
     1621 atacagatct ctctactatg tttctatatt ctcaaagtta aatacaggtt ttcatgcaaa
     1681 tattcatgta gaagtagtga gtgtaataat atgatttagg ttatttcagt gtttaactgt
     1741 gaaaagccac ttgtcttaaa atgcttaaat ataaaagaaa atgcaaaata a
//
