LOCUS       NM_001195338            2509 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus BBSome interacting protein 1 (Bbip1), transcript
            variant 1, mRNA.
ACCESSION   NM_001195338 XR_105986 XR_105987 XR_107196 XR_107197
VERSION     NM_001195338.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2509)
  AUTHORS   Tsyklauri,O., Niederlova,V., Forsythe,E., Prasai,A., Drobek,A.,
            Kasparek,P., Sparks,K., Trachtulec,Z., Prochazka,J., Sedlacek,R.,
            Beales,P., Huranova,M. and Stepanek,O.
  TITLE     Bardet-Biedl Syndrome ciliopathy is linked to altered hematopoiesis
            and dysregulated self-tolerance
  JOURNAL   EMBO Rep 22 (2), e50785 (2021)
   PUBMED   33426789
REFERENCE   3  (bases 1 to 2509)
  AUTHORS   Collin,G.B., Gogna,N., Chang,B., Damkham,N., Pinkney,J., Hyde,L.F.,
            Stone,L., Naggert,J.K., Nishina,P.M. and Krebs,M.P.
  TITLE     Mouse Models of Inherited Retinal Degeneration with Photoreceptor
            Cell Loss
  JOURNAL   Cells 9 (4), 931 (2020)
   PUBMED   32290105
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2509)
  AUTHORS   Dubail,J., Vasudevan,D., Wang,L.W., Earp,S.E., Jenkins,M.W.,
            Haltiwanger,R.S. and Apte,S.S.
  TITLE     Impaired ADAMTS9 secretion: A potential mechanism for eye defects
            in Peters Plus Syndrome
  JOURNAL   Sci Rep 6, 33974 (2016)
   PUBMED   27687499
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2509)
  AUTHORS   Loktev,A.V. and Jackson,P.K.
  TITLE     Neuropeptide Y family receptors traffic via the Bardet-Biedl
            syndrome pathway to signal in neuronal primary cilia
  JOURNAL   Cell Rep 5 (5), 1316-1329 (2013)
   PUBMED   24316073
REFERENCE   6  (bases 1 to 2509)
  AUTHORS   Loktev,A.V., Zhang,Q., Beck,J.S., Searby,C.C., Scheetz,T.E.,
            Bazan,J.F., Slusarski,D.C., Sheffield,V.C., Jackson,P.K. and
            Nachury,M.V.
  TITLE     A BBSome subunit links ciliogenesis, microtubule stability, and
            acetylation
  JOURNAL   Dev Cell 15 (6), 854-865 (2008)
   PUBMED   19081074
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117612.9 and BC062276.1.
            
            On or before Dec 24, 2011 this sequence version replaced
            XR_105987.1, XR_105986.1, XR_107196.1, XR_107197.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011697.1, BC054437.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164133, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-399               AC117612.9         91603-92001         c
            400-1061            BC062276.1         1-662
            1062-2509           AC117612.9         77030-78477         c
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 48.8 cM"
     gene            1..2509
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /note="BBSome interacting protein 1"
                     /db_xref="GeneID:100503572"
                     /db_xref="MGI:MGI:1913610"
     exon            1..472
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /inference="alignment:Splign:2.1.0"
     exon            473..586
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /inference="alignment:Splign:2.1.0"
     exon            587..662
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /inference="alignment:Splign:2.1.0"
     CDS             617..820
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /note="BBSome-interacting protein of 10 kDa"
                     /codon_start=1
                     /product="BBSome-interacting protein 1"
                     /protein_id="NP_001182267.1"
                     /db_xref="CCDS:CCDS57147.1"
                     /db_xref="GeneID:100503572"
                     /db_xref="MGI:MGI:1913610"
                     /translation="MAEVKSMFREVLPKQGQLSVEDVTTMVLCKPKLLPLKSLTLEKL
                     EKMQQAAQDTVRQQEMAEKATSK"
     exon            663..2509
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1134..1139
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /note="hexamer: AATAAA"
     polyA_site      1155
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /note="major polyA site"
     regulatory      2288..2293
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
                     /note="hexamer: AATAAA"
     polyA_site      2311
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
     polyA_site      2509
                     /gene="Bbip1"
                     /gene_synonym="2310002J21Rik; 2610002B11Rik;
                     4930560M04Rik; Ncrna00081"
ORIGIN      
        1 actgggcgcc gctggctagc tccgccacag agaaaagcct ccagccgggt agagaaacga
       61 ctcccagtcg gaagttacgg ttgaagccca ggcagccata attgatgatg gcaggaggcg
      121 tttcctgtca cccgtttgac gtacgttttt cctgcttttg gttccccgtt accccaggca
      181 acagcagagc ggtctggaaa gggatgcacc tgtaagtata cttacggagg atgtgcacac
      241 acacagtcca cactgggcga gttaattcgc gatcgggaac tgccggtttg cttgccagac
      301 cctttacgga gcccctgatc gcttacctag aactacagtt tagggcttca aaactccctc
      361 gcaccggaag ttgcgcttgc acttcctagt agggtcatgg ccaggaggtg ggagtagccg
      421 gaccccgcct gcgccccagg gggtgcctcc tctcccagag ctgacgagtg agacattgtc
      481 tcatgtagtt ccttctgtgg acgtttggag tcaagaagtc aatcgttctg ataactacag
      541 attggattcc taaaggtgca agaaaaaaaa aaagaacaat tttcaggcgc aaaagactgc
      601 atccagcact ttacagatgg cagaagtgaa gtcgatgttc cgagaagtcc ttccaaaaca
      661 agggcagttg tctgtggaag atgtaaccac aatggtgctg tgtaaaccca agctcttgcc
      721 cttaaaatct ctgacgctgg aaaaactgga gaaaatgcag caagcagcac aggatacagt
      781 ccgtcaacaa gaaatggcag aaaaggcaac gagcaaataa gccactagtt accaccactg
      841 taggggatgc cccatcttaa cccctaactg ttcgtaacta gaaactattc tgcatctgca
      901 ggctagaaat gcttaaacta gaccgtcaac attttaaaac acaaaatgtg ggtgttcaaa
      961 cattggtttg tgttcaaagc aaaactctga agcaagtttc atggaatttt gaaagttttt
     1021 aaaattataa atttctcact ttctcagttt atttaccata actactgtta tgaatgtaag
     1081 acattaaatg catcttttat ggatgaagga tttattagaa acatgaatct gaaaataaac
     1141 tttaatgtga atatattgtt gggcttgtac actacccaaa atacacataa gcaagtgtgg
     1201 gccacatcat gctgactgct acggagcctg accagtgaca gcaggaataa ccaactggtc
     1261 tttaggaaac cttcaatagg tctggagaga tggctcagag gttaagagca ctgactgctc
     1321 tctaccagag gtcctgagtt caaatcccag caaccacatg gtagctcaca accatctgta
     1381 atgagatctg atgccctctt caggtgtgtc tgaagacagc tacactgtac ttagatacaa
     1441 tcttttttta aaaaaaagga caccttcagc tatagacaga acgctcagga actaagctcc
     1501 taattacacc aatgttaaga aacagagaat tacacaactg ctactcaagt cccaaataca
     1561 aaccctgagc tgcttattat agcaaaaact caggtgacat gagcctaaaa gagccgtgaa
     1621 gtttgaacac tagagggttt ctttctaaga gatggtacct aaccctgtaa ccaaggaact
     1681 gtttggaaaa ttatacatgt aatgattttg ctgcagtcac caaacacctt cagttaccac
     1741 agatcttgaa accttgctaa taactaggct ttataaagag gctagaggta acttatttat
     1801 tggtagttaa atattggtaa tttagataaa tctaagcttt aagtacttaa gagaatgctt
     1861 ttttaaaaca cgttacaata taagggtaag atctatttat atattagaca aatttcactc
     1921 attaactcta gttatataat aaacagaaaa ttaaagtgca tgtgtatttc cctaggataa
     1981 ccttaaaagg cctttaacta ttacagtttt taaaatgtgt aatacatgtc ggtgtgtatg
     2041 cacctgtatg caggtgccca tggaagcacg agaagacagc tgatccccta cacctttatt
     2101 cttggcactc aagcctccca ggcagaaaga ctggactacc taaacaatta tcaggccagc
     2161 cagagctata gagcaggttc tgtctcaaga agcaatgaaa catttttgtt tggtttgcac
     2221 tgttaggatt gaacacaagg cctagtgagg tttaaacagg aaacctaaaa gaagtttcaa
     2281 aagacacaat aaatgcactc ccactaaaga atcaacagtg tttcacatgt tttattttgc
     2341 tgtacattct tgtagaaccg ggttcgtttt tccagttttg tagaaaaata gatgttccag
     2401 ccaccattta cttaactgtc taatatttaa gaccaatcaa tatgttccct ggaaagatga
     2461 aaaagtctca tgactaactc gtttttttaa aaattcttta aaacaaaaa
//
