LOCUS       NM_026505               5040 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus BMP and activin membrane-bound inhibitor (Bambi),
            mRNA.
ACCESSION   NM_026505
VERSION     NM_026505.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5040)
  AUTHORS   Morrison,J.A., Pushel,I., McLennan,R., McKinney,M.C., Gogol,M.M.,
            Scott,A., Krumlauf,R. and Kulesa,P.M.
  TITLE     Comparative analysis of neural crest development in the chick and
            mouse
  JOURNAL   Dev Biol 519, 142-149 (2025)
   PUBMED   39716593
REFERENCE   2  (bases 1 to 5040)
  AUTHORS   Zhu,Z., Zou,Q., Wang,C., Li,D., Yang,Y., Xiao,Y., Jin,Y., Yan,J.,
            Luo,L., Sun,Y. and Liang,X.
  TITLE     Isl Identifies the Extraembryonic Mesodermal/Allantois Progenitors
            and is Required for Placenta Morphogenesis and Vasculature
            Formation
  JOURNAL   Adv Sci (Weinh) 11 (32), e2400238 (2024)
   PUBMED   38923264
REFERENCE   3  (bases 1 to 5040)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 5040)
  AUTHORS   Wang,L., Si,W., Yu,X., Piffko,A., Dou,X., Ding,X., Bugno,J.,
            Yang,K., Wen,C., Zhang,L., Chen,D., Huang,X., Wang,J., Arina,A.,
            Pitroda,S., Chmura,S.J., He,C., Liang,H.L. and Weichselbaum,R.
  TITLE     Epitranscriptional regulation of TGF-beta pseudoreceptor BAMBI by
            m6A/YTHDF2 drives extrinsic radioresistance
  JOURNAL   J Clin Invest 133 (24), e172919 (2023)
   PUBMED   38099498
  REMARK    GeneRIF: Epitranscriptional regulation of TGF-beta pseudoreceptor
            BAMBI by m6A/YTHDF2 drives extrinsic radioresistance.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5040)
  AUTHORS   De Bono,C., Liu,Y., Ferrena,A., Valentine,A., Zheng,D. and
            Morrow,B.E.
  TITLE     Single-cell transcriptomics uncovers a non-autonomous
            Tbx1-dependent genetic program controlling cardiac neural crest
            cell development
  JOURNAL   Nat Commun 14 (1), 1551 (2023)
   PUBMED   36941249
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5040)
  AUTHORS   Shan,S.W., Tang,M.K., Cai,D.Q., Chui,Y.L., Chow,P.H., Grotewold,L.
            and Lee,K.K.
  TITLE     Comparative proteomic analysis identifies protein disulfide
            isomerase and peroxiredoxin 1 as new players involved in embryonic
            interdigital cell death
  JOURNAL   Dev Dyn 233 (2), 266-281 (2005)
   PUBMED   15858817
REFERENCE   7  (bases 1 to 5040)
  AUTHORS   Suzuki,K., Bachiller,D., Chen,Y.P., Kamikawa,M., Ogi,H.,
            Haraguchi,R., Ogino,Y., Minami,Y., Mishina,Y., Ahn,K.,
            Crenshaw,E.B. 3rd and Yamada,G.
  TITLE     Regulation of outgrowth and apoptosis for the terminal appendage:
            external genitalia development by concerted actions of BMP
            signaling [corrected]
  JOURNAL   Development 130 (25), 6209-6220 (2003)
   PUBMED   14602679
  REMARK    Erratum:[Development. 2003 Dec;130(26):6643]
REFERENCE   8  (bases 1 to 5040)
  AUTHORS   Knight,C., Papagerakis,P., Simmons,D., Berdal,A. and MacDougall,M.
  TITLE     Genomic organization and localization of mouse Nma/BAMBI: possible
            implications related to ameloblastoma formation
  JOURNAL   Connect Tissue Res 43 (2-3), 359-364 (2002)
   PUBMED   12489181
  REMARK    GeneRIF: and has implications in tumor progression. Genomic
            organization of the mouse Nma/BAMBI gene and confirmed the
            chromosomal mapping to human chromosome 10 and mouse chromosome 2.
REFERENCE   9  (bases 1 to 5040)
  AUTHORS   Knight,C., Simmons,D., Gu,T.T., Gluhak-Heinrich,J., Pavlin,D.,
            Zeichner-David,M. and MacDougall,M.
  TITLE     Cloning, characterization, and tissue expression pattern of mouse
            Nma/BAMBI during odontogenesis
  JOURNAL   J Dent Res 80 (10), 1895-1902 (2001)
   PUBMED   11706948
REFERENCE   10 (bases 1 to 5040)
  AUTHORS   Grotewold,L., Plum,M., Dildrop,R., Peters,T. and Ruther,U.
  TITLE     Bambi is coexpressed with Bmp-4 during mouse embryogenesis
  JOURNAL   Mech Dev 100 (2), 327-330 (2001)
   PUBMED   11165491
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC140240.2.
            
            On Nov 17, 2006 this sequence version replaced NM_026505.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045192.1, AK143185.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-329               AC140240.2         76930-77258         c
            330-617             AC140240.2         73671-73958         c
            618-5040            AC140240.2         68811-73233         c
FEATURES             Location/Qualifiers
     source          1..5040
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 2.3 cM"
     gene            1..5040
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /note="BMP and activin membrane-bound inhibitor"
                     /db_xref="GeneID:68010"
                     /db_xref="MGI:MGI:1915260"
     exon            1..329
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             254..1036
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /note="putative transmembrane protein NMA; BMP and activin
                     membrane-bound inhibitor, homolog"
                     /codon_start=1
                     /product="BMP and activin membrane-bound inhibitor homolog
                     precursor"
                     /protein_id="NP_080781.1"
                     /db_xref="CCDS:CCDS29034.1"
                     /db_xref="GeneID:68010"
                     /db_xref="MGI:MGI:1915260"
                     /translation="MDRHSSYFFIWLQLELCAMAVLLTKGEIRCYCDAAHCVATGYMC
                     KSELSACFSRLLDPQNTNSPLTHGCLDSLASTADICRAKQAQNHSGPAMPTLECCHED
                     MCNYRGLHDVLSPSKSEASGQGNRYQHDSSRNLITKMQELTSSKELWFRAAVIAVPIA
                     GGLILVLLIMLALRMLRSENKRLQDERQQMLSRLHYSFHGHHSKKGQVAKLDLECMVP
                     VSGQENCCLTCDKMRQAELSNEKILSLVHWGMYSGHGKLEFI"
     exon            330..617
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            618..5040
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1370..1375
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /note="hexamer: AATATA"
     polyA_site      1393
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /note="major polyA site"
     regulatory      2014..2019
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2038
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
     regulatory      5018..5023
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      5039
                     /gene="Bambi"
                     /gene_synonym="2610003H06Rik"
ORIGIN      
        1 gtgtaggcgt tgctctctgt ggttacgtcc agttcccgtc cgctgttcgt ggcttgtgcg
       61 cgggctggcg gggcgagagg acgaccgccg aggagcgcgc gggtccggga acgtgtcctc
      121 ggtagtctta gtcccgctca atgcttcggc ccccgcccgg acactgacgg cgcccgggct
      181 cgtgctcggc gcgccccggg ggtcgtagtg cagccgcgcc tggctcccgg agcgacggga
      241 gcgcgaggcg tcaatggatc gccactccag ctacttcttc atctggctgc agctggagct
      301 ctgcgccatg gctgtgctgc tcaccaaagg agagatcaga tgctactgtg atgctgctca
      361 ctgtgtggca acaggttaca tgtgtaagtc tgagcttagt gcctgcttct ccagacttct
      421 cgatcctcag aacaccaatt ctccactcac ccacggctgc ctggactcac ttgcaagcac
      481 ggcagacatc tgccgagcca aacaggccca aaaccactct ggccctgcca tgcccacttt
      541 ggaatgctgt cacgaagaca tgtgcaatta tcgaggactg catgacgtcc tctctccttc
      601 caagagcgaa gcctcaggac aaggaaaccg gtatcagcat gacagcagca gaaacctcat
      661 cactaagatg caggagctga cttcctccaa agaactgtgg ttccgcgcag ctgtgatagc
      721 ggttcccatt gctggcggac tgatcttggt gctgctcatt atgttggcct tgcgaatgct
      781 tcgaagtgag aacaagaggc tgcaggatga gcggcagcag atgctgtccc gtctgcacta
      841 cagctttcac ggacaccatt ccaagaaggg gcaagttgca aagttggact tggagtgcat
      901 ggtgcctgtc agtgggcagg agaactgctg tctgacctgt gacaaaatgc ggcaagcaga
      961 gctcagtaat gagaagatcc tctcccttgt gcactggggc atgtacagtg gtcatggaaa
     1021 gctggaattc atatgacagt catgtctgaa ctataaatgg aacccttgaa ggccttctga
     1081 gttctgctga caggagcact tttatctgga gacaactaac tcgcttagtc atcttggaga
     1141 aacaaaatga cctctgaaaa gagaatcttg ggtatttctt ctgaaggatt atttgcacag
     1201 attctacagt caaatggatt aatttgcttt aaagttataa aaagcaaaga gaggactctg
     1261 cacactttcc cagggttctt tgtgtcctag ggagctgcag ctgactgaag taaaaacact
     1321 gtgctctctg taagctccta catcctcatt tattgtaaag attttttaaa atatatatat
     1381 ttttgtccga aaatttagtg gtgtctttca tgaattaaaa cttcagacgg gtgtggggag
     1441 gctggtggtg gtgcagtgca gtggtaagat gcttgcttgt ctggtgtgcg tgaggccctg
     1501 gctgtgattt ctccagcacc acagaaagcc aatcagtcaa aaaacatttg atttggaagt
     1561 gtatgagagt acatgttaat tatatgaatg aaaatccgtt tactcatact tctcaaatgt
     1621 aggttttgat cttgttcatt cttacacaaa cgtataatta attatctttg tgtaatgacc
     1681 attgtcgagt gtctcactta cagttgtttt ccagaatggt tctggtttta gttttcatgt
     1741 aagaactttg cttgtttgtg ctaaaagttg tgcatgctaa gtgcacagtc tctaccacta
     1801 agctactccc caagctctag gaattcctca ctcacttgtg ccagaccaca taggacatga
     1861 gtgtctgaag ttgccgtgac aaaaggagtg ttttatcagc ttcatccgct ttctctgcaa
     1921 cgactgtgac tatgtccacc tcccccagct caagaatgtc cttagtaaag gtaactacta
     1981 tctactgtga cagtttattt tgtctccaac caaattaaat atttcgtctc caaaactagc
     2041 caaactttgt taagcaatgc tcctggtctt taaacatttt tatacttaaa gagtatctgt
     2101 ttctaaatat ctttttagtc cttaagaagg ctttcagtag tgattgtcat taaattgaca
     2161 ttttaataac acaactatta ggtttcctct tcaaaatgtc ccttaatata accaaataga
     2221 atatgacaga acatgaaggt aacattttgt ctcctctaca actttcttta ccttgtttat
     2281 ggacctttcc ctcaaatgga tctttgttat gttaaatatg agaatttctt ttatgtacct
     2341 gatttttttt tttttaactt gaacctgtag cctgcatatt tgaagatgag atttgcctgt
     2401 atctttgcat actttcacta gggtactaaa cataatttga agttccttaa gagcagtgcc
     2461 acctgtgtgg actaatgagc tgaagtgact agcagggaaa tgagcaccta gatttttttt
     2521 tttccctctc aggatatggt ctcactaggt atttggctgt gctgtaagtc attgtggaga
     2581 ccaggctagc ctcctttagg gggcactaat cagataccct gcatatcaga tatttgtatt
     2641 atgattcata acagcaatta caattatgaa gtagcagtga aatgatttta tgcttggggt
     2701 catcacaaat gaggaactgt atttaaagag tttcagcatt agaaggattg agagccctgc
     2761 tttaaaagtg tcactctaca ttctctagtg ctgtggaggc acagtctcct ctatctgctc
     2821 cttatttgcg aatttcaggt cactttgaat tagcatttca gcagctcatt agaaaaaaaa
     2881 cgagggaagc cttgagtttt gaaaggctgt aacatctgtg tgcaccaccc cgcaggaaag
     2941 gcttgggtct gcccagtgtg aaggtctcct gcaagcagaa tgcagggtct cctgtgcttc
     3001 tgtgtttgcc tggcctgttt cctgttcttt gtaggcactc acgagtctac tccaacctgt
     3061 cctgtggggt agggactcat agtccctctg actttcctgg gtatccagct ctagctgtct
     3121 gaaatgacac cccttttcct aagagcaaat cctgtgttta gcttcatctt gacctctcca
     3181 cagcttgctc tgttgttgaa tgtaggttct tctgcatttt agcttactgg cttccctgtg
     3241 agggctgaac actcacagta ggaggcagag ctgtccatct gctttggtga tccaagagtg
     3301 gtatgatgat tccttcatta gttcatttct ctattagggg tttgtgcata tattttgagg
     3361 aggctatgta aggctctact acccagaaca gcctttgttt agcaatgaca tagaacactc
     3421 tcccccaaag taattttcct ttctaagtgg aaacttgctc aaaccagaca caaatggagc
     3481 taagattgtc atgatgtttc tgtatctata ccccgaaagt cttagccctt ttggaagaga
     3541 ttgatccgaa cccgattttg tcttttatgt tttttccttc ttatttcaga tggcttagag
     3601 gcttcctaga aattgactgg tgtgtctcta atttctgttg aactgatttt attaaaaaca
     3661 ctgcaccata gggggtttga ccttctaaaa tactaaacat gtctgcttta gaaaatcaca
     3721 aagctctcct ctgaagtgcc cgtaaatctg gtttcaatat gggttgatta taggctgaaa
     3781 gcttgaaggc aggggcatct agcatggcag atgcagaact gcccttctca gggccaggac
     3841 agctttttcc ccttagaacg tctaattggt cctcttctgt gcctcttagc ctaaataact
     3901 ttaaacctcc agagctgtgt gaatttcagc aaactggaaa caaattgagt gtttcatttt
     3961 gttgcctgga gaatgggaac aataatataa cttaagataa ttacagtaaa aaaactgaat
     4021 atcaggcctg agtttaatct ctcagaggga gtgggcagat gctgtaattc tgttaagaac
     4081 tcaaaagaaa aggagcacat ctttaatctt aggacttggg aagtagaggc aagaggatct
     4141 cggtgagttt gaggccatcc ttgtctacat agcaagttcc aggacagcca gggctacaca
     4201 gagattctgt ctcaaaacaa aacacccccc aaagccccaa acaaaacaaa acaaaacacc
     4261 ccaggaaaaa acttaaacaa acaaacaaac caaccaatca aactaacaac acaaaacagt
     4321 tacctaatac ttgtgaagcc ttgggttcaa tctctaggat caagagaaaa agttaatgct
     4381 gggcaaatgc aggcaaatct gtgacagttg agttctaggt cagctaaggc tacataatga
     4441 gtccttgtct ctaaacaaca aaaatcaaaa ccaaaacaac cccccccccc ccgatttggg
     4501 gatgaatgac tgacttatat ggtaggttgt ttttaattga ttttgaattg tttcaaattt
     4561 gcatatttga gatgggcagc ttttcagtaa actgctggct ggacttagca atgtagtact
     4621 catgtgctgt ttctgtgtat gcttttctca cacatactga atacttaggt ttataattgt
     4681 ttcctttggg gataactgta gggtcactgg aagaatgtta atctcctgta tctgtttcct
     4741 tcctgagttc tcttagagtt ccagatacac tggtgagact cggtgagggg cagatcatat
     4801 ctcagccgcc cttggaggct ggattcattc tacacagtca ccaccatcag ttaaaacatg
     4861 cctataggtg cttccagtaa agtgcaagtc gttgctgtac tgccttctgg aattttacca
     4921 cagagttggg gttttgtaag tgaagaacta tttaatttct ttggaaaagg tcatttgttt
     4981 gatttgtcat tttttggacc attgttataa ttgaagaatt aaatgctgtg ctgccagttc
//
