LOCUS       NM_080640               2626 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus brain and acute leukemia, cytoplasmic (Baalc), mRNA.
ACCESSION   NM_080640
VERSION     NM_080640.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2626)
  AUTHORS   Eisfeld,A.K., Schwind,S., Patel,R., Huang,X., Santhanam,R.,
            Walker,C.J., Markowitz,J., Hoag,K.W., Jarvinen,T.M., Leffel,B.,
            Perrotti,D., Carson,W.E. 3rd, Marcucci,G., Bloomfield,C.D. and de
            la Chapelle,A.
  TITLE     Intronic miR-3151 within BAALC drives leukemogenesis by
            deregulating the TP53 pathway
  JOURNAL   Sci Signal 7 (321), ra36 (2014)
   PUBMED   24736457
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2626)
  AUTHORS   Satoskar,A.A., Tanner,S.M., Weinstein,M., Qualman,S.J. and de la
            Chapelle,A.
  TITLE     Baalc, a marker of mesoderm and muscle
  JOURNAL   Gene Expr Patterns 5 (4), 463-473 (2005)
   PUBMED   15749074
  REMARK    GeneRIF: BAALC/Baalc is a marker of the mesodermal lineage,
            especially muscle.
REFERENCE   3  (bases 1 to 2626)
  AUTHORS   Tanner,S.M., Austin,J.L., Leone,G., Rush,L.J., Plass,C.,
            Heinonen,K., Mrozek,K., Sill,H., Knuutila,S., Kolitz,J.E.,
            Archer,K.J., Caligiuri,M.A., Bloomfield,C.D. and de La Chapelle,A.
  TITLE     BAALC, the human member of a novel mammalian neuroectoderm gene
            lineage, is implicated in hematopoiesis and acute leukemia
  JOURNAL   Proc Natl Acad Sci U S A 98 (24), 13901-13906 (2001)
   PUBMED   11707601
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FO082315.3 and AC164883.5.
            
            On Apr 16, 2020 this sequence version replaced NM_080640.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK079337.1, AK045383.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-312               FO082315.3         3924-4235
            313-479             AC164883.5         51460-51626
            480-2626            AC164883.5         66668-68814
FEATURES             Location/Qualifiers
     source          1..2626
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 15.18 cM"
     gene            1..2626
                     /gene="Baalc"
                     /gene_synonym="2810457D07Rik"
                     /note="brain and acute leukemia, cytoplasmic"
                     /db_xref="GeneID:118452"
                     /db_xref="MGI:MGI:1928704"
     exon            1..312
                     /gene="Baalc"
                     /gene_synonym="2810457D07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..590
                     /gene="Baalc"
                     /gene_synonym="2810457D07Rik"
                     /note="brain and acute leukemia cytoplasmic protein"
                     /codon_start=1
                     /product="brain and acute leukemia cytoplasmic protein
                     isoform 1-6-8"
                     /protein_id="NP_542371.1"
                     /db_xref="GeneID:118452"
                     /db_xref="MGI:MGI:1928704"
                     /translation="MGCGGSRADAIEPRYYESWTRETESTWLTYTDSDALPSAAATDS
                     GPEAGGLHAGVLEDGLSSNGVLRPAAPGGIANPEKKMNCGTQCPNSQNLSSGPLTQKQ
                     NGLWATEAKRDAKRMSAREVAINVTENIRQMDRSKRVTKNCIN"
     exon            313..479
                     /gene="Baalc"
                     /gene_synonym="2810457D07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            480..2626
                     /gene="Baalc"
                     /gene_synonym="2810457D07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2602..2607
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Baalc"
                     /gene_synonym="2810457D07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2626
                     /gene="Baalc"
                     /gene_synonym="2810457D07Rik"
                     /note="major polyA site"
ORIGIN      
        1 gggagcccgg cgctggcagc ggctctggcg gttaggggac caatgtcgct gccgccgcct
       61 cctcctcggg ggccggagct gcgtcgcccg ggctgagcag cagccacagc cgcaagccga
      121 gcggccgccg ggcgcgcccg caacacggga ggatgggctg cggcgggagc cgagccgatg
      181 ccatcgagcc ccgctactac gagagttgga cccgggagac ggagtccacc tggctcacct
      241 acaccgactc ggacgcgctg cccagcgccg cagccacgga cagcggcccc gaggcgggcg
      301 gcctgcacgc gggtgtgctg gaagacggac tgtcctctaa cggggtgctc cgacctgcag
      361 ccccgggtgg aatagccaac ccagagaaga agatgaactg tgggacccaa tgtcccaact
      421 cacagaacct cagctcaggc cctctgaccc agaaacagaa tggcctctgg gccacagagg
      481 ctaagaggga tgctaagcgg atgtctgcaa gagaagtggc tattaatgtt acagagaata
      541 ttcggcagat ggacagaagt aaaagggtca ccaagaactg catcaattag cagtgcccgg
      601 atctggaggc agatgaactt cttggtggag tctagtcaaa gaatcctgaa gaagttgatg
      661 tcactcgatg agtgtggatg cctctgagtg acacacggcc acccaacgct gtgacgaaca
      721 tctcggtttc ctgtttatca catatagaaa atacatcgaa aagtcctgaa atatgttcat
      781 agattgccaa aatgtggttt gtttttcccc tctgcagctt ccgtagcatg gtctgctgta
      841 gccatggtga ctggcacaga aaggctggag taacggaatc cctgtcaagg agctcacact
      901 cgtgcagagc tttctcagtg tgtggttgca gacaaactcc ttctttcctc ctttcctttt
      961 aaatacggcc accacaaaat ttactgtttt cacttaagag ctggctccca gccaactcta
     1021 aatccagaaa tacaagaatc caaaaaacca gagagacttg gaacgagctg aatcagtccc
     1081 agcttcacgt gctggctccc cggtgcctac tcggtgtctt tgagaggtgt ctatgagaca
     1141 cgcacatgca cacgcgcgca cacacacaca catacctgtt tctcctctac ctggaaagga
     1201 ctcccaggct agcatccagg cgttggcttc caaaccagaa tgtcacatgc ctgtggcctt
     1261 tgctcccttt gggacctagc ttcatgttgc ttttccccat agctttccag ttccctattg
     1321 ttctggtggg ctttgtacct tcagtcaggt ggtcatttgc agctggacac cactcacagg
     1381 ggggaaagtg acctaggaac acatggtggc acacgtgata cccctttggc ccttctgtac
     1441 acagccccaa ggaccatgtt atttttggta tctgcagagt aattagtttg gaaagccaga
     1501 ggctggttga tgtatattcc tgttgacata gtctaacaag gcactcactg tattgaaaaa
     1561 caggcaccaa catggtaaag cgatgctttg ataggaaccc ttccccagca ttcctaagca
     1621 caccttcctg cagagtatga cacagcatga gtctgaaagg actgttaaca tgcttgggct
     1681 tattaaggtc caagtcatat caaactgtac caacaaactc acatctagca gcaatagtag
     1741 tctggcggca tgcttacgtg acagttcaag agaagtcacc caagcggatt aagatgcaga
     1801 tgctcactgc tgtctctgac ttatttctcc aacacaagta gaactgtaga ctgtatgttt
     1861 attagtgtta agattcactg ccaaccttgt gccagctaca gtaacagtcg cagagggatt
     1921 tggagtcggg aagtcacgac tgtacttctg actctgtgag gaggcttggt actcaggaga
     1981 ctgacacgga ccctgtggca caagaccaat gattgcagtg gaatctcaca cttaggtaaa
     2041 ggtagctttc tgtcaatcac agatgtatgt cttctccttt gccgtataca ccacagttcc
     2101 cccgccaccc ccaacctctc tcatcttgac tccttgtcaa agggctttta gggaacttca
     2161 tgttctgaca atttaactaa taaaacaaaa gcaagccccg tgactcctgt gtcctcagcg
     2221 gcattgctgg gcaggagtcc ttccacaggg ttggccatgg gtccaatcct gcaagctcaa
     2281 gggcttgcgc tccagggcat gtgcgctgtg ttttgacatg ctgcttcccc agttgatgct
     2341 atcggccatg ggctaaggcc ggcttctctt cccaactctg tgtttgcctc agctcattgg
     2401 aatttaccat ctgggaaagt tgtctctgca aatacagaaa cacgttctca ctctgcgagg
     2461 agaagggagg gagggaggga gggcctgtga tctggcacac cattgaaatt tccatctggc
     2521 aagttttaaa tgtgtgttta aagcaggaac tgactcttac tatcctagtg ggataacact
     2581 ttccattctg aagtttgtgt caataaagtc attaatttca aacata
//
