LOCUS       NM_001362154            1012 bp    mRNA    linear   ROD 17-DEC-2024
DEFINITION  Mus musculus B9 protein domain 2 (B9d2), transcript variant 1,
            mRNA.
ACCESSION   NM_001362154 XM_006539854
VERSION     NM_001362154.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1012)
  AUTHORS   Riehl,D.R., Sharma,A., Roewe,J., Reinhardt,C., Schafer,K. and
            Bosmann,M.
  TITLE     Reply to Chong et al.: Investigating TGFbeta1 biological activities
            using genetically engineered mouse strains
  JOURNAL   Proc Natl Acad Sci U S A 121 (44), e2408647121 (2024)
   PUBMED   39423253
REFERENCE   2  (bases 1 to 1012)
  AUTHORS   Martinez-Mayer,J., Brinkmeier,M.L., O'Connell,S.P., Ukagwu,A.,
            Marti,M.A., Miras,M., Forclaz,M.V., Benzrihen,M.G., Cheung,L.Y.M.,
            Camper,S.A., Ellsworth,B.S., Raetzman,L.T., Perez-Millan,M.I. and
            Davis,S.W.
  TITLE     Knockout mice with pituitary malformations help identify human
            cases of hypopituitarism
  JOURNAL   Genome Med 16 (1), 75 (2024)
   PUBMED   38822427
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1012)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 1012)
  AUTHORS   Chong,D.L.W., Mikolasch,T.A., Sahota,J., Rebeyrol,C.,
            Garthwaite,H.S., Booth,H.L., Heightman,M., Denneny,E.K., Jose,R.J.,
            Khawaja,A.A., Duckworth,A., Labelle,M., Scotton,C.J. and
            Porter,J.C.
  TITLE     Investigating the role of platelets and platelet-derived
            transforming growth factor-beta in idiopathic pulmonary fibrosis
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 325 (4), L487-L499 (2023)
   PUBMED   37643008
REFERENCE   5  (bases 1 to 1012)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1012)
  AUTHORS   Gutcher,I., Donkor,M.K., Ma,Q., Rudensky,A.Y., Flavell,R.A. and
            Li,M.O.
  TITLE     Autocrine transforming growth factor-beta1 promotes in vivo Th17
            cell differentiation
  JOURNAL   Immunity 34 (3), 396-408 (2011)
   PUBMED   21435587
REFERENCE   7  (bases 1 to 1012)
  AUTHORS   Breunig,J.J., Sarkisian,M.R., Arellano,J.I., Morozov,Y.M.,
            Ayoub,A.E., Sojitra,S., Wang,B., Flavell,R.A., Rakic,P. and Town,T.
  TITLE     Primary cilia regulate hippocampal neurogenesis by mediating sonic
            hedgehog signaling
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 13127-13132 (2008)
   PUBMED   18728187
REFERENCE   8  (bases 1 to 1012)
  AUTHORS   Town,T., Breunig,J.J., Sarkisian,M.R., Spilianakis,C., Ayoub,A.E.,
            Liu,X., Ferrandino,A.F., Gallagher,A.R., Li,M.O., Rakic,P. and
            Flavell,R.A.
  TITLE     The stumpy gene is required for mammalian ciliogenesis
  JOURNAL   Proc Natl Acad Sci U S A 105 (8), 2853-2858 (2008)
   PUBMED   18287022
REFERENCE   9  (bases 1 to 1012)
  AUTHORS   Kaplan,D.H., Li,M.O., Jenison,M.C., Shlomchik,W.D., Flavell,R.A.
            and Shlomchik,M.J.
  TITLE     Autocrine/paracrine TGFbeta1 is required for the development of
            epidermal Langerhans cells
  JOURNAL   J Exp Med 204 (11), 2545-2552 (2007)
   PUBMED   17938236
REFERENCE   10 (bases 1 to 1012)
  AUTHORS   Li,M.O., Wan,Y.Y. and Flavell,R.A.
  TITLE     T cell-produced transforming growth factor-beta1 controls T cell
            tolerance and regulates Th1- and Th17-cell differentiation
  JOURNAL   Immunity 26 (5), 579-591 (2007)
   PUBMED   17481928
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK141500.1 and BX517802.1.
            
            On Apr 6, 2018 this sequence version replaced XM_006539854.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141500.1, SRR1660815.94621.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-991               AK141500.1         2-992
            992-1012            BX517802.1         402-422
FEATURES             Location/Qualifiers
     source          1..1012
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.97 cM"
     gene            1..1012
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /note="B9 protein domain 2"
                     /db_xref="GeneID:232987"
                     /db_xref="MGI:MGI:2387643"
     exon            1..199
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /inference="alignment:Splign:2.1.0"
     exon            200..291
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..731
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /codon_start=1
                     /product="B9 domain-containing protein 2"
                     /protein_id="NP_001349083.1"
                     /db_xref="CCDS:CCDS20992.1"
                     /db_xref="GeneID:232987"
                     /db_xref="MGI:MGI:2387643"
                     /translation="MAEVHVIGQIIGATGFSESSLFCKWGIHTGAAWKLLSGVREGQT
                     QVDTPQIGDMAYWSHPIDLHFATKGLQGWPRLHLQVWSQDSFGRCQLAGYGFCHVPSS
                     PGTHQLDCPTWRPLGSWREQLARAFVGGGPQLLHADTIYSGADRYRLHTAAGGTVHLG
                     IGLLLRHFDRYGVEC"
     exon            292..417
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /inference="alignment:Splign:2.1.0"
     exon            418..999
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /inference="alignment:Splign:2.1.0"
     regulatory      972..977
                     /regulatory_class="polyA_signal_sequence"
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /note="hexamer: AATAAA"
     polyA_site      999
                     /gene="B9d2"
                     /gene_synonym="stumpy"
                     /note="major polyA site"
ORIGIN      
        1 aggggaggaa cctgctgttg ccccagcaac agtcggggca ccccaggaga gcgaggctgc
       61 ggatctatct acctcagatc tccctccgcc tggaagggcc cgggagggga gcgagactag
      121 tctcgacggc gcccgcaaag aagcccgtga actaccatcc ccgaggcagc tttcacttct
      181 aacggtcaag tacgcggaga gccatggctg aagtgcacgt gatcgggcag atcatagggg
      241 ccaccggttt ctcggaaagc agcctctttt gcaagtgggg catccacaca ggggccgcat
      301 ggaagctcct ctcaggtgta cgagaaggcc agacacaggt agacacaccc cagatagggg
      361 acatggctta ctggtcccac cccattgacc tgcacttcgc tactaaaggt ctccaaggtt
      421 ggcctcgact ccatctccag gtgtggtccc aggacagctt tggccgctgc cagcttgctg
      481 gctatggctt ttgccatgtg cctagcagcc caggcactca tcagctggac tgccctacat
      541 ggaggcccct gggcagttgg agggagcagc tagcacgggc tttcgtgggt ggtgggccac
      601 agctgctgca cgcagatacc atctacagcg gggctgaccg ctaccgcctg cacacggccg
      661 cgggtggcac agtgcacctt ggtatcggcc tgctgctgcg ccacttcgat cgctatggag
      721 tggagtgttg agggacttca ttgctactaa tcgccatcat ccactgagca cataatggca
      781 cagcagtgaa gcaggcacgt ggactctgga gactgtcagt cctgatcacc cccaagtcat
      841 ggcccctatg ccatggactg caaggccagg aactcccctg tggcccatgc tccactgaac
      901 tacggggtag aaagggctgt gggttggagg gacatgagca gggcccactg tttggactgt
      961 cgggggcact taataaaagc gtgtatttct catgggtaaa aaaaaaaaaa aa
//
