LOCUS       NM_001253381            2467 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase,
            polypeptide 2 (B4galt2), transcript variant 1, mRNA.
ACCESSION   NM_001253381
VERSION     NM_001253381.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2467)
  AUTHORS   Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J,
            Stein F, Schultz C, Sauer U and Aulehla A.
  TITLE     Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to
            Mouse Embryo Mesoderm Development
  JOURNAL   Dev Cell 40 (4), 331-341 (2017)
   PUBMED   28245920
REFERENCE   2  (bases 1 to 2467)
  AUTHORS   Malcuit C, Trask MC, Santiago L, Beaudoin E, Tremblay KD and Mager
            J.
  TITLE     Identification of novel oocyte and granulosa cell markers
  JOURNAL   Gene Expr Patterns 9 (6), 404-410 (2009)
   PUBMED   19539053
REFERENCE   3  (bases 1 to 2467)
  AUTHORS   Yoshihara T, Sugihara K, Kizuka Y, Oka S and Asano M.
  TITLE     Learning/memory impairment and reduced expression of the HNK-1
            carbohydrate in beta4-galactosyltransferase-II-deficient mice
  JOURNAL   J Biol Chem 284 (18), 12550-12561 (2009)
   PUBMED   19265195
REFERENCE   4  (bases 1 to 2467)
  AUTHORS   Nakamura N, Yamakawa N, Sato T, Tojo H, Tachi C and Furukawa K.
  TITLE     Differential gene expression of beta-1,4-galactosyltransferases I,
            II and V during mouse brain development
  JOURNAL   J Neurochem 76 (1), 29-38 (2001)
   PUBMED   11145975
REFERENCE   5  (bases 1 to 2467)
  AUTHORS   Lo NW, Shaper JH, Pevsner J and Shaper NL.
  TITLE     The expanding beta 4-galactosyltransferase gene family: messages
            from the databanks
  JOURNAL   Glycobiology 8 (5), 517-526 (1998)
   PUBMED   9597550
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL627128.16.
            
            [WARNING] On Dec 6, 2023 this sequence was replaced by
            NM_001253381.2.
            
            Transcript Variant: This variant (1) represents the longer
            protein-coding transcript. Variants 1 and 2 both encode the same
            protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC145335.1, SRR14777535.2393833.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-375               AL627128.16        121934-122308       c
            376-417             AL627128.16        120608-120649       c
            418-808             AL627128.16        120147-120537       c
            809-1044            AL627128.16        119700-119935       c
            1045-1235           AL627128.16        116271-116461       c
            1236-1358           AL627128.16        115929-116051       c
            1359-1463           AL627128.16        115712-115816       c
            1464-2467           AL627128.16        111832-112835       c
FEATURES             Location/Qualifiers
     source          1..2467
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 53.7 cM"
     gene            1..2467
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /note="UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase,
                     polypeptide 2"
                     /db_xref="GeneID:53418"
                     /db_xref="MGI:MGI:1858493"
     exon            1..375
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
     exon            376..417
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
     exon            418..808
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             505..1614
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /EC_number="2.4.1.22"
                     /EC_number="2.4.1.90"
                     /EC_number="2.4.1.38"
                     /note="beta-1,4-galactosyltransferase II; b4Gal-T2;
                     beta4Gal-T2; beta-1,4-GalTase 2; UDP-Gal:beta-GlcNAc
                     beta-1,4-galactosyltransferase 2;
                     UDP-galactose:beta-N-acetylglucosamine
                     beta-1,4-galactosyltransferase 2; nal synthase; lactose
                     synthase A protein; N-acetyllactosamine synthase;
                     beta-N-acetylglucosaminyl-glycolipid
                     beta-1,4-galactosyltransferase;
                     beta-N-acetylglucosaminylglycopeptide
                     beta-1,4-galactosyltransferase"
                     /codon_start=1
                     /product="beta-1,4-galactosyltransferase 2"
                     /protein_id="NP_001240310.1"
                     /db_xref="CCDS:CCDS18539.1"
                     /db_xref="GeneID:53418"
                     /db_xref="MGI:MGI:1858493"
                     /translation="MSRLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSR
                     FSTRSPAHALYPAASSSTNCSRPNATAASSGLPEVPSARPGPTAPVIPPCPDVPPGLV
                     GRVVIEFTSPMPLERVQRENPGVLLGGRYSPPDCTPAQTVAVIIPFRHREHHLRYWLH
                     YLHPMLRRQRLRYGVYVINQHGEETFNRAKLLNVGFLEALKEDAAYDCFIFSDVDLVP
                     MDDRNLYRCGDQPRHFAIAMDKFGFRLPYASYFGGVSGLSKAQFLRINGFPNEYWGWG
                     GEDDDIFNRISLTGMKISRPDVRIGRYRMIKHDRDKHNEPNPQRFNKIQNTKMSMKWD
                     GIGSVRYRVLEVSRQPLFTNITVDIGQPMSWLTQG"
     exon            809..1044
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1235
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1358
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1463
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..2467
                     /gene="B4galt2"
                     /gene_synonym="Ggtb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccctccga ggagccgtag cgcgggaggg aggcggcagc gcagtggtcc gtcggtccgc
       61 cggtccgtgg gtctgccggg ccccgccctg cctcccgggg cggctcggct ccatggcccg
      121 cggcggcggc gggaggtggc cccggagcct cggggaccgc tgaccgggcg gtggggccgg
      181 gccatggggg acagagccgt ccacagctgc tggagccggg atccctaccc gagctggagc
      241 ggcgccccct gctgagcccc gagcgctgcg agagaggagg gcgcgcgcgg ccccccaccc
      301 agggccccga cattccagac ccggcccggc tagggggccg cccgcgcgcc gtcacagatc
      361 ccagcccagg acccggtaga acacaaacaa gcccgtgagt gtcaaggtgt atgaaagtct
      421 gacctgtggg atctctctct ccctctgttc aggctgtcag ccggatgctt gggcccattg
      481 ggcgggccat tggccacttg cgggatgagc agactgctgg gggggacgct ggagcgggtc
      541 tgcaaggctg tgctccttct ctgcctgctg cacttccttg tggccgtcat cctctacttt
      601 gacgtctatg cccagcacct ggcctttttc agccgcttca gtacccgaag cccagcccat
      661 gccctctacc ctgcagccag cagcagtacc aactgctctc ggcccaacgc cactgccgct
      721 agctccgggc tgcctgaagt gcccagtgcc aggcctggtc ccacagctcc agtcattccg
      781 ccctgtcctg acgtgccgcc tggtcttgtg ggccgagtgg tcatcgaatt cacctcaccc
      841 atgcctctgg aacgggtgca gagggaaaat ccaggcgtgc tcctgggcgg ccgctattct
      901 ccacccgact gcaccccagc ccaaacggtg gcagtcatca tcccctttag acaccgggag
      961 caccacctac gctattggct ccactatctg caccccatgt tgaggcggca gcggctgcgc
     1021 tacggtgtct atgtcatcaa ccagcatggc gaggagacct tcaaccgagc caagctgctc
     1081 aacgtgggct tcctagaggc actgaaggag gatgctgcct atgactgctt catcttcagt
     1141 gatgtggacc tggtccctat ggatgaccgc aatctgtacc gttgtggtga ccagccccgc
     1201 cactttgcca tcgccatgga caagtttggc ttccggttgc cctatgctag ctactttgga
     1261 ggtgtgtcgg gcctgagcaa ggcccagttt ctgaggatca atggctttcc caacgagtac
     1321 tggggctggg gtggcgagga tgatgacatc ttcaaccgga tctccctgac tgggatgaag
     1381 atctcacgcc cggatgtccg gattggccgc taccgcatga tcaagcacga ccgggacaaa
     1441 cataacgagc ccaaccctca gaggtttaat aagattcaaa acacaaagat gagcatgaag
     1501 tgggacggca ttggatccgt gcggtaccga gtcttggaag tgtctcggca accgctcttc
     1561 accaacatca cagtggacat tggacagccc atgtcgtggc tcactcaagg ctgacactaa
     1621 cggaccaagg ccctccatgc ttttctagta tggaaggctg cctgccagag gcctgacctc
     1681 cagcctggct gacagctgct ctaagggttg tccccaagac tgtgactgtg agctgttttc
     1741 tgagtctaat agacagctgc acctagaagt tccagcattc actttgaggg gcgtttgggc
     1801 aagccccact tatggccctc tctggggtca acccctcttc ctgtcctact tttcccagcc
     1861 caaacctcct cacttttagg gttgggccag cccctgcact gcctcgcgga gtggcctggg
     1921 ctaggtcact ccacctctct gtgcctcaat ttccccactc ccctcgagtc ccctagggcc
     1981 tgaaaaggtg ggaggtttga ctagggggca gtgtctcttc caggggggaa ttcctcagat
     2041 ctggagaccc ctcatgcttc caggggaggg gaaacctttt tcattcaaca ttgtaggggg
     2101 caagctttgg tgagccacct actgaggagc acccccagga ggggaccaga aggggtgctg
     2161 tgttgtttcc tgggaccatg gggttgacct ttgcatgagg gacaggtggg gcctggatca
     2221 gtcaatggat ctggcctccc tcccttagag aggaggcagg agccccaggg cctgctctgt
     2281 ttatatgttg cacagaaact tgtgtgggtg ctttagtaaa aaacgttaac ggagcagccc
     2341 ccttgtctgt ctgtgaacgg gatctggatt cccgaagcta gtttgtgttg tgggaggtga
     2401 cctggctagg gtcttctagt aacttaataa atttcctagc cctgccactt ccactgttac
     2461 agggaga
//
