LOCUS       NM_001036740            1475 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus UDP-GlcNAc:betaGal
            beta-1,3-N-acetylglucosaminyltransferase 8 (B3gnt8), transcript
            variant 2, mRNA.
ACCESSION   NM_001036740
VERSION     NM_001036740.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1475)
  AUTHORS   Seko,A. and Yamashita,K.
  TITLE     Activation of beta1,3-N-acetylglucosaminyltransferase-2
            (beta3Gn-T2) by beta3Gn-T8. Possible involvement of beta3Gn-T8 in
            increasing poly-N-acetyllactosamine chains in differentiated HL-60
            cells
  JOURNAL   J Biol Chem 283 (48), 33094-33100 (2008)
   PUBMED   18826941
  REMARK    GeneRIF: up-regulation of beta3Gn-T8 in differentiated cells
            increases poly-N-acetyllactosamine chains by activating intrinsic
            beta3Gn-T2.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY206280.1, BY320287.1, AK042388.1 and BY554292.1.
            
            On Apr 14, 2006 this sequence version replaced NM_001036740.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY206280.1, BC025206.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                BY206280.1         1-99
            100-391             BY320287.1         84-375
            392-1470            AK042388.1         767-1845
            1471-1475           BY554292.1         531-535
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.94 cM"
     gene            1..1475
                     /gene="B3gnt8"
                     /gene_synonym="B3galt7; B7galt7"
                     /note="UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 8"
                     /db_xref="GeneID:232984"
                     /db_xref="MGI:MGI:2385269"
     exon            1..99
                     /gene="B3gnt8"
                     /gene_synonym="B3galt7; B7galt7"
                     /inference="alignment:Splign:2.1.0"
     exon            100..1475
                     /gene="B3gnt8"
                     /gene_synonym="B3galt7; B7galt7"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..1301
                     /gene="B3gnt8"
                     /gene_synonym="B3galt7; B7galt7"
                     /note="UDP-Gal:betaGal beta 1,3-galactosyltransferase
                     polypeptide 7; BGnT-8; beta3Gn-T8; beta-1,3-Gn-T8;
                     beta-1,3-N-acetylglucosaminyltransferase 8"
                     /codon_start=1
                     /product="UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 8"
                     /protein_id="NP_001031817.1"
                     /db_xref="CCDS:CCDS20989.1"
                     /db_xref="GeneID:232984"
                     /db_xref="MGI:MGI:2385269"
                     /translation="MRCRKCQLCLSALLTLLGLKVYIEWTSESWLKKAEPRGALPSPT
                     PPNAEPTLPTNLSARLGQTGPLSSAYWNQQQRQLGVLPSTDCQTWGTVAASEILDFIL
                     YPQELRRFLLSAACRSFPLWLPAGEGSPVASCSDKDVPYLLLAVKSEPGHFAARQAVR
                     ETWGSPVAGTRLLFLLGSPLGMGGPDLRSLVTWESRRYGDLLLWDFLDVPYNRTLKDL
                     LLLTWLSHHCPDVNFVLQVQDDAFVHIPALLEHLQTLPPTWARSLYLGEIFTQAKPLR
                     KPGGPFYVPKTFFEGDYPAYASGGGYVISGRLAPWLLQAAARVAPFPFDDVYTGFCFR
                     ALGLAPRAHPGFLTAWPAERTRDPCAVRGLLLVHPVSPQDTIWLWRHLWVPELQC"
ORIGIN      
        1 gggctgggcc gacagcttga ggacgcacag ctgcgaggag ggagtccggg cagggcttta
       61 cccgaggacc cccagagctg gcggaagctg gacccagagc cccactggtg gccctttccc
      121 tgggccgggt catgcgttgc cgcaagtgcc agctctgcct gtcagcactg ctcacactcc
      181 tgggcctcaa agtatacatc gagtggacat ccgagtcctg gcttaaaaag gctgaacccc
      241 ggggcgctct gcccagtccc acaccaccca atgctgagcc cactctgccc accaacctct
      301 cagcacgcct gggtcagact ggcccactgt cctctgctta ctggaaccag cagcagcggc
      361 agctgggagt cctgcccagt acggactgtc agacttgggg gactgttgct gcctcggaga
      421 tcttggactt catcctgtac ccccaggagc ttcggcgctt cttgctgtcg gcggcctgta
      481 ggagctttcc actatggctg cctgcaggag aaggcagccc tgtggccagc tgctctgata
      541 aggatgtacc ctacttgcta ctggctgtca aatcagaacc aggacacttt gcagcacggc
      601 aggctgtgag ggagacctgg ggcagcccag ttgctgggac ccggttgctc ttcctgctgg
      661 ggtcccccct aggaatgggg gggcctgact taagatcact ggtgacgtgg gaaagccggc
      721 gctatggtga cctactgctc tgggacttcc tggatgttcc ctacaaccgg acactcaagg
      781 acctgctgct gctgacctgg ctgagccacc actgccccga tgtcaatttt gtcctgcagg
      841 ttcaggatga tgcctttgtg cacatcccag ccctactgga gcacctgcag actctgccac
      901 ccacctgggc ccgcagcctc tacctgggtg agatcttcac ccaggccaaa ccgctccgca
      961 agcccggagg acccttctat gtgccgaaga ccttctttga aggggactat ccagcctatg
     1021 cgagtggagg tggctatgta atctcaggac gcctggcacc ctggctgctg caggcggcag
     1081 ctcgcgtggc acccttcccc tttgatgatg tctacactgg cttctgcttc cgtgccctgg
     1141 gcttagcacc ccgtgcccat ccaggcttcc tcacagcctg gccagcagaa cgtaccaggg
     1201 acccctgcgc cgtgcgaggc ctgctcttgg tgcatccagt cagccctcag gacaccattt
     1261 ggctctggag acatctgtgg gtcccagagc tccagtgctg accggcagag acaagctggg
     1321 gtgggtgggt gctgacctgg cctgagtctc tcctagagac aagctggggt gggtggggct
     1381 gacctggcct gagtctctcc taaacccttc ttagccaagg tggcagactg tgtttatcta
     1441 ctttatggtt ttgaaaaatg tgtccttcct actcc
//
