LOCUS       NM_080445               3213 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus UDP-Gal:betaGal beta 1,3-galactosyltransferase,
            polypeptide 6 (B3galt6), mRNA.
ACCESSION   NM_080445
VERSION     NM_080445.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3213)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3213)
  AUTHORS   Sun,X., Mahajan,D., Chen,B., Song,Z. and Lu,L.
  TITLE     A quantitative study of the Golgi retention of glycosyltransferases
  JOURNAL   J Cell Sci 134 (20) (2021)
   PUBMED   34533190
REFERENCE   3  (bases 1 to 3213)
  AUTHORS   Cajigas,I., Chakraborty,A., Swyter,K.R., Luo,H., Bastidas,M.,
            Nigro,M., Morris,E.R., Chen,S., VanGompel,M.J.W., Leib,D.,
            Kohtz,S.J., Martina,M., Koh,S., Ay,F. and Kohtz,J.D.
  TITLE     The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially
            Organizes Megabase Distant Genes in the Developing Forebrain
  JOURNAL   Mol Cell 71 (6), 956-972 (2018)
   PUBMED   30146317
REFERENCE   4  (bases 1 to 3213)
  AUTHORS   Mukhopadhyay,P., Brock,G., Webb,C., Pisano,M.M. and Greene,R.M.
  TITLE     Strain-specific modifier genes governing craniofacial phenotypes
  JOURNAL   Birth Defects Res A Clin Mol Teratol 94 (3), 162-175 (2012)
   PUBMED   22371338
REFERENCE   5  (bases 1 to 3213)
  AUTHORS   Bai,X., Zhou,D., Brown,J.R., Crawford,B.E., Hennet,T. and Esko,J.D.
  TITLE     Biosynthesis of the linkage region of glycosaminoglycans: cloning
            and activity of galactosyltransferase II, the sixth member of the
            beta 1,3-galactosyltransferase family (beta 3GalT6)
  JOURNAL   J Biol Chem 276 (51), 48189-48195 (2001)
   PUBMED   11551958
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB660643.1, AK078083.1 and AK033608.1.
            
            On May 25, 2007 this sequence version replaced NM_080445.3.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                BB660643.1         2-30
            30-2150             AK078083.1         2-2122
            2151-3213           AK033608.1         2062-3124
FEATURES             Location/Qualifiers
     source          1..3213
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 87.66 cM"
     gene            1..3213
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
                     /note="UDP-Gal:betaGal beta 1,3-galactosyltransferase,
                     polypeptide 6"
                     /db_xref="GeneID:117592"
                     /db_xref="MGI:MGI:2152819"
     exon            1..3213
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..1040
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
                     /EC_number="2.4.1.134"
                     /note="beta-1,3-galactosyltransferase 6; GAG GalTII;
                     beta3GalT6; beta3Gal-T6; beta-1,3-GalTase 6;
                     galactosyltransferase II; galactosylxylosylprotein
                     3-beta-galactosyltransferase; UDP-Gal:betaGlcNAc beta
                     1,3-galactosyltransferase, polypeptide 6"
                     /codon_start=1
                     /product="beta-1,3-galactosyltransferase 6 precursor"
                     /protein_id="NP_536693.1"
                     /db_xref="CCDS:CCDS19053.1"
                     /db_xref="GeneID:117592"
                     /db_xref="MGI:MGI:2152819"
                     /translation="MKVFRRAWRHRVALGLGGLAFCGTTLLYLARCASEGETPSASGA
                     ARPRAKAFLAVLVASAPRAVERRTAVRSTWLAPERRGGPEDVWARFAVGTGGLGSEER
                     RALELEQAQHGDLLLLPALRDAYENLTAKVLAMLTWLDERVDFEFVLKADDDSFARLD
                     AILVDLRAREPARRRRLYWGFFSGRGRVKPGGRWREAAWQLCDYYLPYALGGGYVLSA
                     DLVHYLRLSREYLRAWHSEDVSLGTWLAPVDVQREHDPRFDTEYKSRGCNNQYLVTHK
                     QSPEDMLEKQQMLLHEGRLCKHEVQLRLSYVYDWSAPPSQCCQRKEGVP"
     regulatory      1817..1822
                     /regulatory_class="polyA_signal_sequence"
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
                     /note="hexamer: ACTAAA"
     polyA_site      1841
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
                     /note="major polyA site"
     polyA_site      1958
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
     regulatory      2125..2130
                     /regulatory_class="polyA_signal_sequence"
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
                     /note="hexamer: TATAAA"
     polyA_site      2152
                     /gene="B3galt6"
                     /gene_synonym="GalTII"
ORIGIN      
        1 gagtcgcgca ggcgccttcc agcgtccgcg cctgcgctcc tcggcggcct ctcgcccgca
       61 gcatgaaggt attccggcgc gcttggcggc accgggtggc gctgggccta ggcggcctgg
      121 cgttctgcgg caccactctg ttgtacctgg cgcgctgcgc ttccgagggc gagacgccct
      181 ccgcttccgg agccgctcgg ccccgcgcta aggccttcct ggcggtgctg gtggccagtg
      241 cgccccgcgc ggtcgagcgc cgcaccgcag tgcgcagcac gtggctggca ccggagaggc
      301 gtggcggacc cgaggacgtg tgggcgcgct tcgccgtggg cactggcggc ttaggctcgg
      361 aggagcggcg cgctcttgag ctcgagcagg cgcagcacgg ggacctgctg ctgctgcccg
      421 ccctgcgcga cgcctacgag aacctcacgg ccaaggtcct ggccatgctg acctggctgg
      481 atgagcgcgt ggacttcgag ttcgtgctca aggcggacga cgactccttt gcgcgcctgg
      541 acgctatcct ggtggaccta cgcgcacggg agcccgcacg ccgccggcgc ctctactggg
      601 gcttcttttc cgggcgcggg cgcgtcaagc cgggaggtcg ctggcgagaa gcagcctggc
      661 aactctgcga ctactacctg ccctacgcgt tgggcggtgg ctatgtcctt tctgcggacc
      721 tggtgcatta cctgcgcctc agccgcgagt acctgcgcgc gtggcacagt gaagacgtat
      781 cgctgggcac ctggctggca ccagtggatg tgcaacggga gcacgaccca cgcttcgaca
      841 cggagtacaa atctcgaggc tgcaacaatc agtatctggt gacacacaag caaagcccag
      901 aggacatgtt ggagaagcaa cagatgttgc tgcatgaggg ccggttgtgc aagcatgagg
      961 tgcagttgcg cctttcctat gtctatgact ggtcagctcc accctcccag tgctgccagc
     1021 gcaaggaggg cgttccctga tgtcactgca ggtgccgggg tctctcctga cacaggccaa
     1081 gcatcctgaa caatctgata aatgatctgg gctgagcttg gtttatccaa ttgctgttga
     1141 gaccttggga ctgatggcca gagacagcta acaatgtcta gtccactgag ggtgccatta
     1201 gtggtctggt gtaaggccta cccaaggaca tctggttatg aatgtggaga ttgcatctga
     1261 gcgcgtgcgc gcgcacgcgc gcgcacacac acacacacat gcacacacac tgaccatgta
     1321 atgccaccta tcagccatct ggagtgtgag ggaagggcct cctcacttga tgagtttaga
     1381 gtgccctcat tctgcaaact ctgcagctca ctgcccatct tgattgttct gcacagcctc
     1441 acctgcagac tgtgttgaat tcatctcaaa atgttacttg tcaaagttgt ctttgtattg
     1501 ttcagacaga gttccattct gttgtgtctc ccgtttttta tcttttgtca tggacaagta
     1561 tgaggtttga cttgattttc aagtcaacta ggttagaatt tttgtctcag tggatagagg
     1621 ttgataaata taatgcagtt tgcttagacc tatttataaa tattgtatgc ttgcatagat
     1681 aagaatttac agaggcaggc aaatctctgg gttcaaggcc agcctggtct acagagtgag
     1741 tccaggatag ccaggactat gcagagaaac ccttaaattt ttttaagttg ggagtgcacg
     1801 tcttaattta tttttaacta aaggaaaata cttgtgtcag attttgtatc tgtggattaa
     1861 tctgtcaaca gcctaagtgg ccaaccccac ttctgggtgt gtttaaagca tagaagaata
     1921 tttaaactat ccatttctct ttcaggttta cacataaatc agtctttttg tgtgtgtgtt
     1981 tgtttctgaa cagacatgac ttttaaagct tttcagggtg tgtgagcgta tggactgtaa
     2041 ggcacttggg atcagaatgt ccacacaaag tttgtctttc aaagtggttt attcacacca
     2101 acagtcttta cagtatcggg ctaatataaa agttaagcag ctgtctcacc aagcaggttc
     2161 caccgtgtga tctctgggaa tacatttcag aatacttctc agccaccacc caccgtcaag
     2221 gccttcagtt atcaattgtg gccgactcca aggaggtcct tgagagtgta agcatgtggc
     2281 cagtcaatgg cgggcttaag tgggcggagt aacagcacct gaagttccgg ggtgactgag
     2341 gccagggcca ccaagagagt ctcaagtccc ttaggtatca acatgggagg gtatggaagc
     2401 cttgtcacag gaacattgac agtatgatcg attgacaggc catccccagg gttctcattt
     2461 ccttgggttc acggccatat cagtgccacc ttaaggttag ttcattagca tatcaaggcc
     2521 tattctggac tgcagggtgg gctgccagtg gatttgcttc tgaggtgtag ctcttgtcaa
     2581 agctgcctag tggcaaactc gagcattatt tcaaatcaca caagaaggcc tttgagttac
     2641 acaacatggt ttttaaacta tgttccatac aagcttccac aaagaccttc agattcctgg
     2701 tgtctcagca aagtttcaga gatccaaacc tgtgttgagg cttcctagag tctctcttaa
     2761 ggaaataata tttgctacct agcatagcac cccaaccaca caaactttaa cagtagtaca
     2821 tatccccttt taatgtttaa aaaaattaag agtatactta gaaaaatata ataaggtggc
     2881 tccaggataa atggacaacc tgagctggcc atgacctcca gctttggatg atgttgcaat
     2941 ctctgctatt ttaatgggac tgatgtttga ggttttgttt ttatgagaca gggtctagct
     3001 atgtagccta gactagactt gaactcaacc ctgcctaatc tcctgactac tgagattaca
     3061 ggcataaacc accaaaccaa gtttacatta actttttgtt tgtttgatct gtatagcctg
     3121 aaggtattcc tgcctgggga actgtggatg cggagagaca tgccctgatt gcctgtcatt
     3181 aatttgcttt taaaatttca ggctgtaaac ttg
//
