LOCUS       NM_001379327            5707 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase,
            polypeptide 1 (B3galt1), transcript variant 4, mRNA.
ACCESSION   NM_001379327 XM_006499591
VERSION     NM_001379327.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5707)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5707)
  AUTHORS   Zhu,D., Shen,A., Wang,Y., Gu,X. and Gu,J.
  TITLE     Developmental regulation of beta-1,3-galactosyltransferase-1 gene
            expression in mouse brain
  JOURNAL   FEBS Lett 538 (1-3), 163-167 (2003)
   PUBMED   12633872
REFERENCE   3  (bases 1 to 5707)
  AUTHORS   Malissard,M., Dinter,A., Berger,E.G. and Hennet,T.
  TITLE     Functional assignment of motifs conserved in beta
            1,3-glycosyltransferases
  JOURNAL   Eur J Biochem 269 (1), 233-239 (2002)
   PUBMED   11784317
REFERENCE   4  (bases 1 to 5707)
  AUTHORS   Hennet,T., Dinter,A., Kuhnert,P., Mattu,T.S., Rudd,P.M. and
            Berger,E.G.
  TITLE     Genomic cloning and expression of three murine UDP-galactose:
            beta-N-acetylglucosamine beta1,3-galactosyltransferase genes
  JOURNAL   J Biol Chem 273 (1), 58-65 (1998)
   PUBMED   9417047
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929411.11, AL929125.1, AL928598.7, AL845519.6 and BX936296.17.
            
            On Mar 30, 2020 this sequence version replaced XM_006499591.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219379.37682.1,
                                           SRR10223970.2380.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-346               AL929411.11        143563-143908
            347-491             AL929125.1         178440-178584
            492-556             AL928598.7         126513-126577
            557-604             AL845519.6         83845-83892
            605-729             BX936296.17        12973-13097
            730-5707            BX936296.17        57237-62214
FEATURES             Location/Qualifiers
     source          1..5707
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 39.53 cM"
     gene            1..5707
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /note="UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase,
                     polypeptide 1"
                     /db_xref="GeneID:26877"
                     /db_xref="MGI:MGI:1349403"
     exon            1..346
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /inference="alignment:Splign:2.1.0"
     exon            347..491
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /inference="alignment:Splign:2.1.0"
     exon            492..556
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /inference="alignment:Splign:2.1.0"
     exon            557..604
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /inference="alignment:Splign:2.1.0"
     exon            605..729
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /inference="alignment:Splign:2.1.0"
     exon            730..5707
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /inference="alignment:Splign:2.1.0"
     CDS             960..1940
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /EC_number="2.4.1.86"
                     /note="UDP-galactose:beta-N-acetylglucosamine beta1,
                     3-galactosyltransferase 1; beta-1,3-GalTase 1"
                     /codon_start=1
                     /product="beta-1,3-galactosyltransferase 1"
                     /protein_id="NP_001366256.1"
                     /db_xref="GeneID:26877"
                     /db_xref="MGI:MGI:1349403"
                     /translation="MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVA
                     RKNFTFGNIRTRPINPHSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWG
                     DENNFKGIKIATLFLLGKNADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGM
                     RWVATFCSKAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRS
                     KWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLG
                     IHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSSKKHLRC"
     regulatory      5687..5692
                     /regulatory_class="polyA_signal_sequence"
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /note="hexamer: AATAAA"
     polyA_site      5707
                     /gene="B3galt1"
                     /gene_synonym="beta3Gal-T1"
                     /note="major polyA site"
ORIGIN      
        1 gtcagtcgcc gaggccagaa ccgtcgccgg ggaagcgcaa cccggctccg gtgctccggc
       61 tgccgccgcg gctgctcggc tggtgcagct gagcgagccc gcgcgggcgc cgctgccgcc
      121 tccgccgccg tccaccgcgc gctgccagca ccgcggggct tgcaggaggc cgccgggagg
      181 ggcgggcgcg cgagctgagc acgaggaggc ggaggcgggg gagaagtgat gctggcgcca
      241 gggatccggg cagcggcagc ggagaataag catcttcggg accccggctg cagcgtccct
      301 gtggcccgcg ggccagcaga acggccagag acggcgcgtc ccgcggatct gttagagcca
      361 cgtcaaggac tgctgtgtcc aggagtggag aaaggcttat gtgagacaag agactctact
      421 gtcagaagaa agcaaatgat ttcatcatag gtaacagctg actcctatct tcagttttgt
      481 gttcctcgaa gaattcactt ggaaaagtca cgtggagcaa ctccagctaa agaagcatga
      541 agactagtct actggggaaa gaagaaatgg gtttccacgg acctatcaat gatactcatc
      601 acaggattct gcaatttggt gtgcatcagc ttttggagtg agcctctcaa atctctacag
      661 accaatggag actaagcaag atgctctgta gctgaactaa gaagaaaggc agcaagtttg
      721 gcccaaaaga gttctgggga agatttctga ggcatggagc ttccagcagg tttggaagaa
      781 agtaaagtga attccatgat gcaacaacac aagtgaggtc tgtggacacc caccaaacca
      841 actcctctct ggcaggaatt ttagattgac gaatactatg ctgcctttgc aaaaggacaa
      901 gaaactagtg cccaaaagac gtgttcttca gcatttggat tagacgtgtt ctcaagacaa
      961 tggcttcaaa ggtctcctgc ctctatgtat tgaccgttgt gtgctgggcc agcgctctct
     1021 ggtacttgag cataaccaga cctacttcat cctacactgg ctccaagccg ttcagtcacc
     1081 taacagttgc caggaaaaac ttcacctttg gcaacataag aactcgacct ataaacccac
     1141 attcttttga atttctgata aatgagccca acaagtgcga gaaaaacatt ccttttctcg
     1201 tgatcctcat tagcaccaca cacaaggaat ttgatgcccg ccaggcaatc cgggagacat
     1261 ggggggatga aaacaacttc aaagggatca agatagccac acttttcctc ctgggcaaaa
     1321 atgctgatcc tgttctgaac cagatggtgg agcaagagag ccagatcttc catgacatca
     1381 tcgtggagga cttcattgac tcctaccaca atctcaccct caaaacctta atggggatga
     1441 gatgggttgc cactttctgt tcaaaagcca agtacgtcat gaaaaccgac agtgacattt
     1501 ttgtgaacat ggacaacctt atttataaac tcctgaaacc ctctaccaag ccaagaagaa
     1561 ggtatttcac tggttacgtc atcaacggcg ggccaatcag ggatgtccgc agtaagtggt
     1621 atatgcctag agatttgtac cctgacagca actacccacc gttctgttca gggactggct
     1681 atatcttttc cgctgatgtg gctgaactca tttacaagac ctcgctccac accaggctgc
     1741 ttcatcttga agatgtgtac gtgggactgt gtcttcgaaa gcttggcatc catcctttcc
     1801 agaatagtgg cttcaatcac tggaaaatgg cctacagttt gtgtcggtac cgccgcgtca
     1861 tcactgtcca ccagatctct ccagaagaaa tgcacagaat ctggaatgac atgtcaagca
     1921 agaagcatct gagatgttag gacttctatt aatgtaaata actttctttt ctaagaaatg
     1981 gggactaaga tgttggtatt tacaggtgtc accaagggaa catgaactgg ccaggggttt
     2041 gtaaatgttt tgctttctgt tcctagttct ttctcggatc agtattttac atgtattggg
     2101 ctcggccata gaaatggtga gagagttaga gggccggatt tcattctcag gtcctaagac
     2161 attgccattt atatcaaaaa gtgactctaa ataactgcca ggattggtgc actgtgcatc
     2221 tgagataaag atctgggcca ggagatagaa actcacagta atgccctcat agcatctctg
     2281 caaacgtaaa tagtaattct ttctttgaaa ataaaaaaat caaaccaagt cagaaaagat
     2341 ccgcagtcag gaacacacac tagatgttat cattaatgct gtgtgctgtt gtcatgtaac
     2401 atttttacat acgttgccat aaaatgtgta tagaatttga gattctacca ataattgatt
     2461 ttatccctag agtagggcat caatgacgaa aaagatggga atgtacactt gaggatcagt
     2521 tatcctgtat gtatagaaaa catttcggca tagattcaca agaattaaat ctggtcagca
     2581 ggtgggttgt acatagaaat gctactttaa gtaaacaagt aaacgttttt tttttcccca
     2641 gaacaaatat tatatgatgc caccaaggag actccaaatg tagtaccctc acctacttcc
     2701 ttccataaat gcctttaagt gcattttatg gtttttggat cagtcaggca tatgtctcca
     2761 tgtgtagaaa acacgttggt aggaggccca gaaataatgc ataacaattg ataaaatgca
     2821 aatctaggtg tccattctaa ttaacataag cttggcaata gtgtacaatg cccctttcac
     2881 acatttgcaa agcacatgag aacatcttta aggagtacca accttattaa aagatgtgcc
     2941 cctgctacca gtagaagaaa tgctctctta gcgtctaaag cattcacata tgtttagtag
     3001 caaaagggct ttgaggtgtt ctggggaatc tgtggctgag atccgtggga aggaagacta
     3061 gggaagccaa gttgggatcc cattgatgcc acaaatttat atggaccatt tgaacaggca
     3121 tctcattttt gatgtgcatc tgtatgctca cttgtaaaat ggctaaaaag aaaaatctac
     3181 ctcacaggta ctgtgagagc aaatcacatt tgctaataag tattttgaga tcttttagtt
     3241 taagaggtgc tacataatgc catgtatcat gcatgatgct aaatgctaaa atgatttaca
     3301 gtaatgataa agatggttat ccattgtggc agcatcatcc taatataaca atttaccaaa
     3361 ataaagattg actgtgaact atcagcgtac ctaattcttc caagacttga tgtttccttg
     3421 gctataagtt agttgattgg ggaagcttca gtttctcccc cacactctct cattttggtg
     3481 aagaattttt cacttcagtg tgttgccttg gcatcccaag atgtttaaag caaaaaaaaa
     3541 aaaatctatt ttgctttggg gaggagcttt gcataggtct tgcaaaacac aacttaaatc
     3601 gtaggaaaca tttgccccgt attcttaaaa ctctttagaa caagtagggc taatctactc
     3661 cctcagagga cgaataagca ctcagcaaat ctccacagtg gcacatctac cgttgatgca
     3721 ccactccttg tcgtgatgca aagaaagctg gaaaagttgc tcatttgagc tattttcttt
     3781 gcaccttgac ctctgcaaaa cccccataga agctgatagt aatggggagt caaaggagta
     3841 aacggagtcc catgatcacg taatcccttg ctaggaaaca cttatatttt atcatcccca
     3901 aagtactgac taatataggg cttcccatcc tttaatatga tggtgtcaag tgacctggga
     3961 gaagatgaag caagacaagg tgagccaccg tcccaccatc tagcctcaaa ccctatgagc
     4021 tccaatggct ggctagcctc ccaccctcgg gcctctttgg cctcgcagca gcaaagctga
     4081 atgcagtctc tgtctcctgc cctggccttg catctcgtcc atgctcagcc cagccacttt
     4141 ccatgtccaa aatcacacac tataataacc acatctgtac atctatgaat tgctttatat
     4201 gtgtgtgcga agtatgtata gagccctaat cttgaaaagg agcaaaaaaa atcaaccaga
     4261 aaatcacttg tcttaaagga ctgtttctta acttttttta tgctacataa tgcccgtatg
     4321 acaaacatgt aaatagacat ccaagagttc atgtacatat tttaaaggcg cttttcttgt
     4381 cacctcaatt gtatgtacgg ctagaacctg cttgatatgt aacattttcc tctgcatgga
     4441 acttgacgag gcaaggccat ttgtccagta tctcaatagc cttaagcatg tttgttcgct
     4501 ctttgggttt tttttttttt ttttggatgt tcaaaaagaa aaaaaatggt taatttgtca
     4561 aggaaaagct ctaattttct acttttgtta attctatgac aagaagctgg tcaaattatt
     4621 gtcatggtta tttattaagc catttataac atttgtttaa gaacaatatt tcataataat
     4681 ggcagtattc tggggctggg ggttttcact cagtggtaaa gcacttgcct agcatgcaaa
     4741 gggctttggg ttcagtcctc agcactgcaa taatacagtt aaaataatgt cagccctact
     4801 gtgccagaag tcactcaaag aatttttcta agtactgtct ggttccccat tatttctcca
     4861 ttatgtactg tataacgtca gcacctaacc tttaaagttt cttcttgtat ttcttagagg
     4921 aaaagatgct ttctctttgg tgcctcattt atgtggcttt gtgaccccct tggagcagtt
     4981 tcaatctaca acaatgtact tttaaataac cagattcaaa acatgaagat cattttttga
     5041 tttgaattaa atatggaagg gcaaaacccc ttgtgtgata agaaatggag gggaaacaaa
     5101 ctctttacag agaagtcaca gaaggagttt ttcaatcaaa tttcttctaa caaaagacaa
     5161 tgggatattt atgtacagtg tgtggaattc attttctacc tttcctaata tgtgcgttca
     5221 aagcggggaa ttgattgtat catttctgta aaggggaaga tactttttat aagccacagg
     5281 taacttgtga atgaaagacg aaattcactg gagacgcttg atgataattg acatttaggt
     5341 atattgttat atatgactga ttgtatttat gtatttattt gctcaaaatt gtacatatgg
     5401 ttttgccaaa agtaactgtg tgttaaagtg cactctttgg gtttgtagta ctatttaggg
     5461 ttacaagggt tgccaatcaa gctgctaatc agaatactat ttttttgtat cggtgttaca
     5521 acatgtgacg aatagacgac actgtctttt cattcatcct ctttcccttc gtcttgaaat
     5581 gtaaaatgtt ggttgaaagc acgatgcaat tgtacaggcc catctgtcaa gaggaagatc
     5641 atggtttcat aagactgatt tttttttttt aaaaacacct gggacaaata aacagaagaa
     5701 gaactca
//
