LOCUS       NM_001410637            2753 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus UDP-GalNAc:betaGlcNAc beta
            1,3-galactosaminyltransferase, polypeptide 1 (B3galnt1), transcript
            variant 2, mRNA.
ACCESSION   NM_001410637 XM_006501529
VERSION     NM_001410637.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2753)
  AUTHORS   Olesen,C., Nyeng,P., Kalisz,M., Jensen,T.H., Moller,M., Tommerup,N.
            and Byskov,A.G.
  TITLE     Global gene expression analysis in fetal mouse ovaries with and
            without meiosis and comparison of selected genes with meiosis in
            the testis
  JOURNAL   Cell Tissue Res 328 (1), 207-221 (2007)
   PUBMED   17431699
REFERENCE   2  (bases 1 to 2753)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   3  (bases 1 to 2753)
  AUTHORS   Fujii,Y., Numata,S., Nakamura,Y., Honda,T., Furukawa,K., Urano,T.,
            Wiels,J., Uchikawa,M., Ozaki,N., Matsuo,S., Sugiura,Y. and
            Furukawa,K.
  TITLE     Murine glycosyltransferases responsible for the expression of
            globo-series glycolipids: cDNA structures, mRNA expression, and
            distribution of their products
  JOURNAL   Glycobiology 15 (12), 1257-1267 (2005)
   PUBMED   16079416
  REMARK    GeneRIF: Gb3 and Gb4 synthase are responsible for the expression of
            globo-series glycolipids
REFERENCE   4  (bases 1 to 2753)
  AUTHORS   Lowe,J.B. and Marth,J.D.
  TITLE     A genetic approach to Mammalian glycan function
  JOURNAL   Annu Rev Biochem 72, 643-691 (2003)
   PUBMED   12676797
  REMARK    Review article
REFERENCE   5  (bases 1 to 2753)
  AUTHORS   Vollrath,B., Fitzgerald,K.J. and Leder,P.
  TITLE     A murine homologue of the Drosophila brainiac gene shows homology
            to glycosyltransferases and is required for preimplantation
            development of the mouse
  JOURNAL   Mol Cell Biol 21 (16), 5688-5697 (2001)
   PUBMED   11463849
REFERENCE   6  (bases 1 to 2753)
  AUTHORS   Hennet,T., Dinter,A., Kuhnert,P., Mattu,T.S., Rudd,P.M. and
            Berger,E.G.
  TITLE     Genomic cloning and expression of three murine UDP-galactose:
            beta-N-acetylglucosamine beta1,3-galactosyltransferase genes
  JOURNAL   J Biol Chem 273 (1), 58-65 (1998)
   PUBMED   9417047
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC111096.15.
            
            On Aug 13, 2022 this sequence version replaced XM_006501529.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.3452846.1,
                                           SRR13422591.140954.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-645               AC111096.15        24146-24790
            646-711             AC111096.15        43727-43792
            712-2753            AC111096.15        47158-49199
FEATURES             Location/Qualifiers
     source          1..2753
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 32.24 cM"
     gene            1..2753
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /note="UDP-GalNAc:betaGlcNAc beta
                     1,3-galactosaminyltransferase, polypeptide 1"
                     /db_xref="GeneID:26879"
                     /db_xref="MGI:MGI:1349405"
     exon            1..645
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /inference="alignment:Splign:2.1.0"
     exon            646..711
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /inference="alignment:Splign:2.1.0"
     exon            712..2753
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /inference="alignment:Splign:2.1.0"
     CDS             746..1741
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /EC_number="2.4.1.79"
                     /note="UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase
                     III; beta-1,3-GalNAc-T1; beta-1,3-GalTase 3; globoside
                     synthase; beta-1,3-galactosyltransferase 3;
                     galactosylgalactosylglucosylceramide
                     beta-D-acetyl-galactosaminyltransferase;
                     UDP-N-acetylgalactosamine:globotriaosylceramide
                     beta-1,3-N-acetylgalactosaminyltransferase;
                     UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase,
                     polypeptide 3; Globoside blood group; Brainiac 1"
                     /codon_start=1
                     /product="UDP-GalNAc:beta-1,
                     3-N-acetylgalactosaminyltransferase 1"
                     /protein_id="NP_001397566.1"
                     /db_xref="GeneID:26879"
                     /db_xref="MGI:MGI:1349405"
                     /translation="MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVI
                     ERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWG
                     EKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTI
                     MAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGF
                     FHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNL
                     LKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY"
     regulatory      2469..2474
                     /regulatory_class="polyA_signal_sequence"
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /note="hexamer: ATTAAA"
     polyA_site      2488
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /note="major polyA site"
     regulatory      2732..2737
                     /regulatory_class="polyA_signal_sequence"
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /note="hexamer: AATAAA"
     polyA_site      2753
                     /gene="B3galnt1"
                     /gene_synonym="b3Gal-T3; B3galt3; b3GT3; beta-3-Gx-T3;
                     beta3GalT3; Mbrn 1"
                     /note="major polyA site"
ORIGIN      
        1 aacagcgata acggcgctgg gctgcggacg cagggacccc gcgcgcgcgc gcgtgcgtga
       61 aggaggcgcg cgcccgcccg ctcggcgtgc gtgcggctgc ggggagtccg tgttcgcgcg
      121 cagagagcga gcgcgggccg caccgttgcg ggtaccacgg gcgcacggga ggtgagtgcg
      181 gggcgggcgg gcgggaggcc gaggcgggga gacggttggg cggctgccga gcgcccctct
      241 ctctcgcggc gcagccttct aggttcgtgg gtcggggctt cgaggccccg ggcgccgctc
      301 gctcctccgt ggagcggggc gccgcgagct gccacgccct gggctctggc ctccgcgcct
      361 ggtctcgggg ctgggtctcg aggctccgga cgagagactc gagaatctgg gccacttgga
      421 ggggcgtcca gtgctcttgg cgagccgggc caccgcggcc tcacggatcc atcctgccct
      481 gccttgagct atgtaagcct cgggggccga ggtagtggtg gcctggttgt caccgcgacc
      541 aaggagaagt ggagaatact gtccgcacgc cacgccgatg gacctgctgc aggcccggag
      601 ggaggaacgc acattctagg cgggaaaggg cctgtggtcc ctagggtgtg agccttctaa
      661 gtagcatatg gcaaaacgtt aggccaagct gtgacagccc ctgtggttaa gaacctgtgc
      721 cttctgaact tctctgctgc tgtggatggc cccggctgtc ttgactgccc ttcccaatag
      781 gatgtcactg agatccctca agtggagcct gctgctgctg tccctgctga gcttcctggt
      841 gatatggtac ctcagcctcc cccactacaa tgtgatcgag cgcgtcaact ggatgtactt
      901 ctatgagtat gagccaattt acagacaaga ctttcgcttc acgctccgcg aacactcgaa
      961 ctgttctcat cagaacccat tcctggtcat cctggtgacc tcacgcccct cagatgtgaa
     1021 agccagacaa gccattagag ttacttgggg tgagaaaaag tcctggtggg gatatgaggt
     1081 gctcacgttt ttcttactag gccagcaggc tgaaagggaa gacaaaacgt tagccctgtc
     1141 cttggaggat gagcacgttc tctatggtga tattatacgg caagactttc tagacacata
     1201 taataacttg accttgaaaa ccattatggc tttcaggtgg gtaatggagt tttgccccaa
     1261 tgccaagtat atcatgaaaa cagacactga tgttttcatc aacactggca atttagtcaa
     1321 gtatctttta aacctaaacc actcagagaa gtttttcacg ggctatcctc taattgataa
     1381 ctattcctat agaggatttt tccataaaaa ccacatttca taccaagagt accccttcaa
     1441 ggtgttccct ccctactgca gcgggctggg ctacattatg tccggcgacc tggtgcccag
     1501 ggtctacgag atgatgagtc acgtgaagcc catcaagttt gaagacgttt atgttggcat
     1561 ctgtttgaat ttgttaaaag tggacattca tattccagaa gacacaaacc ttttctttct
     1621 gtacagaatc cacttggatg tatgtcagct cagacgcgtg attgcagccc atggcttttc
     1681 ttccaaggag atcatcacat tctggcaggt gatgctgagg aacaccacat gccattacta
     1741 agcccatcca tcacccatct aggcaaggga ggaaggacac tgtagacagg gtcagagtta
     1801 gcactgtggg aaactcggga agttgagcat gctggtttgc ctgggctgaa actcatggag
     1861 ctccctagac aggagtcaag gcctgaactt agtgattgct ttcacagaat ttaacttggg
     1921 tcgtttaaag gtgacagagg agtcaaacat aatgcaaacg aagagttttg ctaaccaaat
     1981 caaagggtca gacagtctgg atggctcagg ctgtagatta gaatttctta agatttccct
     2041 aaaagaaaaa ctaactagtc cacagccaga atacagtgtg gagttgtatt tattagacag
     2101 tatagttaca taatggttca gtgtgtatct taagtggtta ttatgtaaag atatatatat
     2161 atatttcttg taaaaagctt tacagagtta tattgaaaac attcatttgt attgttttca
     2221 tttgcaaggt actcaatgat atggtacgta agagttatca aatcaagtat tatttaatgt
     2281 catttcaatt ttctaaatgt ttaaaggtta tgtatggtct cagtattata tgatgaattg
     2341 cctttcacat ttgagctttg ttttattcac cactgatcag tttaattaat gtggcgttaa
     2401 tgtgacatca aaggttatta ctgactgtcc gtaatctgtt gaactctgtt gcactgtaaa
     2461 catagagaat taaagcaaga aaattcaagc tttgtatagt tttttaaaaa tgtagtcagt
     2521 gtttctcgat gtcacttcat ctgtctcatt atcctccaaa gaatttggga ataataagaa
     2581 cttcaggcag atcatttcct aaaggcacag aaggctgaga cggtcttagt gtttactatc
     2641 acagtgtgta agctagaaag gggaagtgga agacccaggt tgtattgtta accctcccag
     2701 tgtgtgtttt ctactgagta atcaatttgt caataaagga tttttaaaaa gca
//
