LOCUS       NM_013478               1315 bp    mRNA    linear   ROD 11-SEP-2024
DEFINITION  Mus musculus alpha-2-glycoprotein 1, zinc (Azgp1), mRNA.
ACCESSION   NM_013478
VERSION     NM_013478.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1315)
  AUTHORS   Yang,S., Yin,Y., Sun,Y., Ai,D., Xia,X., Xu,X. and Song,J.
  TITLE     AZGP1 Aggravates Macrophage M1 Polarization and Pyroptosis in
            Periodontitis
  JOURNAL   J Dent Res 103 (6), 631-641 (2024)
   PUBMED   38491721
  REMARK    GeneRIF: AZGP1 Aggravates Macrophage M1 Polarization and Pyroptosis
            in Periodontitis.
REFERENCE   2  (bases 1 to 1315)
  AUTHORS   Wen,R.M., Qiu,Z., Marti,G.E.W., Peterson,E.E., Marques,F.J.G.,
            Bermudez,A., Wei,Y., Nolley,R., Lam,N., Polasko,A.L., Chiu,C.L.,
            Zhang,D., Cho,S., Karageorgos,G.M., McDonough,E., Chadwick,C.,
            Ginty,F., Jung,K.J., Machiraju,R., Mallick,P., Crowley,L.,
            Pollack,J.R., Zhao,H., Pitteri,S.J. and Brooks,J.D.
  TITLE     AZGP1 deficiency promotes angiogenesis in prostate cancer
  JOURNAL   J Transl Med 22 (1), 383 (2024)
   PUBMED   38659028
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1315)
  AUTHORS   Brutsch,S.M., Madzharova,E., Pantasis,S., Wustemann,T., Gurri,S.,
            Steenbock,H., Gazdhar,A., Kuhn,G., Angel,P., Bellusci,S.,
            Brinckmann,J., Auf dem Keller,U., Werner,S. and Bordoli,M.R.
  TITLE     Mesenchyme-derived vertebrate lonesome kinase controls lung
            organogenesis by altering the matrisome
  JOURNAL   Cell Mol Life Sci 80 (4), 89 (2023)
   PUBMED   36920550
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1315)
  AUTHORS   Sun,H., Ma,F., Chen,W. and Yang,X.
  TITLE     Adipokine ZAG Alters Depression-Like Behavior by Regulating
            Oxidative Stress in Hippocampus
  JOURNAL   Horm Metab Res 54 (4), 259-267 (2022)
   PUBMED   35255519
  REMARK    GeneRIF: Adipokine ZAG Alters Depression-Like Behavior by
            Regulating Oxidative Stress in Hippocampus.
REFERENCE   5  (bases 1 to 1315)
  AUTHORS   Fan,G., Li,Y., Ma,F., Zhao,R. and Yang,X.
  TITLE     Zinc-alpha2-glycoprotein promotes skeletal muscle lipid metabolism
            in cold-stressed mice
  JOURNAL   Endocr J 68 (1), 53-62 (2021)
   PUBMED   32863292
  REMARK    GeneRIF: Zinc-alpha2-glycoprotein promotes skeletal muscle lipid
            metabolism in cold-stressed mice.
REFERENCE   6  (bases 1 to 1315)
  AUTHORS   Quaggin,S.E., Heuvel,G.B., Golden,K., Bodmer,R. and Igarashi,P.
  TITLE     Primary structure, neural-specific expression, and chromosomal
            localization of Cux-2, a second murine homeobox gene related to
            Drosophila cut
  JOURNAL   J Biol Chem 271 (37), 22624-22634 (1996)
   PUBMED   8798433
REFERENCE   7  (bases 1 to 1315)
  AUTHORS   Sharma,S., Leonard,J., Lee,S., Chapman,H.D., Leiter,E.H. and
            Montminy,M.R.
  TITLE     Pancreatic islet expression of the homeobox factor STF-1 relies on
            an E-box motif that binds USF
  JOURNAL   J Biol Chem 271 (4), 2294-2299 (1996)
   PUBMED   8567692
REFERENCE   8  (bases 1 to 1315)
  AUTHORS   Takahara,K., Osborne,L., Elliott,R.W., Tsui,L.C., Scherer,S.W. and
            Greenspan,D.S.
  TITLE     Fine mapping of the human and mouse genes for the type I
            procollagen COOH-terminal proteinase enhancer protein
  JOURNAL   Genomics 31 (2), 253-256 (1996)
   PUBMED   8824813
REFERENCE   9  (bases 1 to 1315)
  AUTHORS   Noguchi,M., Kitabatake,A., Ishibashi,T. and Kasahara,M.
  TITLE     The MHC class I-like Zn-alpha 2-glycoprotein gene maps to mouse
            chromosome 5
  JOURNAL   Immunogenetics 42 (1), 72-74 (1995)
   PUBMED   7797272
REFERENCE   10 (bases 1 to 1315)
  AUTHORS   Ueyama,H., Naitoh,H. and Ohkubo,I.
  TITLE     Structure and expression of rat and mouse mRNAs for Zn-alpha
            2-glycoprotein
  JOURNAL   J Biochem 116 (3), 677-681 (1994)
   PUBMED   7852290
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY101787.1, AK005051.1, BY705112.1 and D18019.1.
            
            On Nov 16, 2007 this sequence version replaced NM_013478.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061646.1, AK005051.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                BY101787.1         1-15
            16-233              AK005051.1         2-219
            234-361             BY705112.1         187-314
            362-1310            AK005051.1         348-1296
            1311-1315           D18019.1           189-193
FEATURES             Location/Qualifiers
     source          1..1315
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 76.92 cM"
     gene            1..1315
                     /gene="Azgp1"
                     /gene_synonym="Zag"
                     /note="alpha-2-glycoprotein 1, zinc"
                     /db_xref="GeneID:12007"
                     /db_xref="MGI:MGI:103163"
     exon            1..100
                     /gene="Azgp1"
                     /gene_synonym="Zag"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..963
                     /gene="Azgp1"
                     /gene_synonym="Zag"
                     /note="major histocompatibility complex class I-like
                     protein; zn-alpha-2-GP"
                     /codon_start=1
                     /product="zinc-alpha-2-glycoprotein precursor"
                     /protein_id="NP_038506.2"
                     /db_xref="CCDS:CCDS19783.1"
                     /db_xref="GeneID:12007"
                     /db_xref="MGI:MGI:103163"
                     /translation="MVPVLLSLPLLLGPAVFQETGSYYLTFLYTGLSRPSKGFPRFQA
                     TAFLNDQAFFHYNSNSGKAEPVGPWSQVEGMEDWEKESQLQRAREEIFLVTLKDIMDY
                     YKDTTGSHTFQGMFGCEITNNRSSGAVWRYAYDGEDFIEFNKEIPAWIPLDPAAANTK
                     LKWEAEKVYVQRAKAYLEEECPEMLKRYLNYSRSHLDRIDPPTVTITSRVIPGGNRIF
                     KCLAYGFYPQRISLHWNKANKKLAFEPERGVFPNGNGTYLSWAEVEVSPQDIDPFFCL
                     IDHRGFSQSLSVQWDRTRKVKDENNVVAQPQ"
     exon            101..361
                     /gene="Azgp1"
                     /gene_synonym="Zag"
                     /inference="alignment:Splign:2.1.0"
     exon            362..637
                     /gene="Azgp1"
                     /gene_synonym="Zag"
                     /inference="alignment:Splign:2.1.0"
     exon            638..1315
                     /gene="Azgp1"
                     /gene_synonym="Zag"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1315
                     /gene="Azgp1"
                     /gene_synonym="Zag"
                     /note="major polyA site"
ORIGIN      
        1 tttcctgtgt agactgttct cccgggcact accgtagcaa tggtgcctgt cctgctgtcc
       61 ctgcctctcc ttctgggtcc tgcagtcttt caggagactg ggtcttatta tctgaccttt
      121 ctctacaccg ggttgtccag acccagcaaa ggttttccga ggtttcaagc cactgcattt
      181 ctcaatgacc aggccttctt ccactacaac agcaacagcg ggaaggcaga gcctgtggga
      241 ccttggagcc aggtggaagg aatggaggac tgggagaagg aaagccagct tcagagggcc
      301 agggaggaga tcttccttgt gaccctgaaa gacatcatgg actattacaa ggacactaca
      361 gggtctcaca cctttcaggg aatgtttggt tgcgagatca caaataacag aagtagtgga
      421 gctgtctgga ggtatgccta cgacggagag gatttcatcg aattcaacaa agaaatccca
      481 gcttggatcc ccttagaccc agcagctgca aacaccaagc taaagtggga agcagaaaag
      541 gtctacgtgc agcgagccaa ggcataccta gaggaggagt gtcctgaaat gctgaagagg
      601 tacctgaact acagtcgatc tcacctggac cgaatagatc ctcccactgt gacaatcacc
      661 agccgtgtga tcccaggagg aaacagaata ttcaaatgcc tggcctatgg cttctaccca
      721 caaagaatta gtctgcactg gaacaaggcc aacaagaagc tagcatttga accagaaaga
      781 ggtgtttttc ccaatggaaa tggcacttac ctctcctggg cagaggtgga agtctcccca
      841 caggacatag accccttctt ctgcctcata gatcacaggg ggttttccca atctctctcg
      901 gtgcagtggg ataggacaag aaaagtaaag gatgaaaaca atgttgtagc tcagcctcag
      961 taagttaccc tctctgcctg acatgagaga ggtgaacttc agaagtcaat gtcatcaaca
     1021 aggtcttcca tgggccactg tacaacagcc agcaagaatc caaggaagag gcatgggcac
     1081 agaagacttg aatgccacag actgagttca ctctcaatgt cagatcaatc gccttgcctt
     1141 gtaaacctcc tccttgatta atctgtcaac cctcacaatt gccctcatgc ctagaacagc
     1201 acagaaagga aggcatttta aactcagaga tgctagagaa gtgtgagttg attttatcat
     1261 gtattctgcc cccacatact tgattcaatt gtgaacatct tcatattcac tcaaa
//
