LOCUS       NM_001346967            3736 bp    mRNA    linear   ROD 12-AUG-2024
DEFINITION  Mus musculus axonemal dynein light chain domain containing 1
            (Axdnd1), mRNA.
ACCESSION   NM_001346967 XM_017313157
VERSION     NM_001346967.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3736)
  AUTHORS   Houston,B.J., Nguyen,J., Merriner,D.J., O'Connor,A.E., Lopes,A.M.,
            Nagirnaja,L., Friedrich,C., Kliesch,S., Tuttelmann,F., Aston,K.I.,
            Conrad,D.F., Hobbs,R.M., Dunleavy,J.E.M. and O'Bryan,M.K.
  TITLE     AXDND1 is required to balance spermatogonial commitment and for
            sperm tail formation in mice and humans
  JOURNAL   Cell Death Dis 15 (7), 499 (2024)
   PUBMED   38997255
  REMARK    GeneRIF: AXDND1 is required to balance spermatogonial commitment
            and for sperm tail formation in mice and humans.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3736)
  AUTHORS   Hiradate,Y., Harima,R., Yanai,R., Hara,K., Nagasawa,K., Osada,M.,
            Kobayashi,T., Matsuyama,M., Kanno,S.I., Yasui,A. and Tanemura,K.
  TITLE     Loss of Axdnd1 causes sterility due to impaired spermatid
            differentiation in mice
  JOURNAL   Reprod Med Biol 21 (1), e12452 (2022)
   PUBMED   35386379
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3736)
  AUTHORS   Ma,Q., Cao,C., Zhuang,C., Luo,X., Li,X., Wan,H., Ye,J., Chen,F.,
            Cui,L., Zhang,Y., Wen,Y., Yuan,S. and Gui,Y.
  TITLE     AXDND1, a novel testis-enriched gene, is required for
            spermiogenesis and male fertility
  JOURNAL   Cell Death Discov 7 (1), 348 (2021)
   PUBMED   34759295
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161221.7 and AC161414.3.
            
            On Nov 9, 2016 this sequence version replaced XM_017313157.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849381
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                AC161221.7         56477-56546
            71-266              AC161221.7         56862-57057
            267-439             AC161221.7         57981-58153
            440-543             AC161221.7         59055-59158
            544-658             AC161221.7         74447-74561
            659-744             AC161221.7         77125-77210
            745-801             AC161221.7         78844-78900
            802-904             AC161221.7         79850-79952
            905-1026            AC161221.7         81839-81960
            1027-1167           AC161221.7         84603-84743
            1168-1272           AC161221.7         85375-85479
            1273-1393           AC161221.7         89281-89401
            1394-1495           AC161221.7         94915-95016
            1496-1659           AC161221.7         96449-96612
            1660-1735           AC161221.7         98935-99010
            1736-1970           AC161221.7         100671-100905
            1971-2172           AC161221.7         111575-111776
            2173-2266           AC161221.7         125941-126034
            2267-2475           AC161221.7         128283-128491
            2476-2572           AC161221.7         130600-130696
            2573-2683           AC161221.7         135498-135608
            2684-3016           AC161221.7         138315-138647
            3017-3118           AC161221.7         141948-142049
            3119-3201           AC161414.3         710-792
            3202-3440           AC161414.3         2252-2490
            3441-3736           AC161414.3         3267-3562
FEATURES             Location/Qualifiers
     source          1..3736
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 67.71 cM"
     gene            1..3736
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /note="axonemal dynein light chain domain containing 1"
                     /db_xref="GeneID:77352"
                     /db_xref="MGI:MGI:1924602"
     exon            1..70
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            71..266
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..3508
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /codon_start=1
                     /product="axonemal dynein light chain domain-containing
                     protein 1"
                     /protein_id="NP_001333896.1"
                     /db_xref="CCDS:CCDS83611.1"
                     /db_xref="GeneID:77352"
                     /db_xref="MGI:MGI:1924602"
                     /translation="MSLHKVSDTSLTSPSTSESKQAKLYVVKEAKGLPELKEKKSMVN
                     HLKPLPPLQNDYRIPEEVLLSLNYAANAGPCPESLLPVKKPKAPKCALPRLVDHVWQH
                     PIRRDKFKYLIDHPVSLTGAGRDISFLYDVKYVKGEAVEKKLCPPNKSTQSQSSAMVP
                     HKEKTLADTLVPEEFHIVSNTGVSGLECYDDKYTTLLTDSENRLLLFPSMKPNKRVEV
                     VQLSNVMDTMLERAGIENENYVGPTKMHQLLNVLKREQSIYNTVFHELIRQVSVDCAD
                     RGELLSKIREKYVQMLDHIAQQMIEFYKDLVTQRMMDQRILQELYNFKNVIEELTREL
                     CLVQAHDRKLTKEAEKVQKNLAEALLEAEKNAKIVEDYHDLYTMQRGRMESDIKLLMT
                     ERDIWSSATYELALKVIERNRVILAKKLYLSEKGWNKYAKHFIIMLSTKDTGDLGMVE
                     KLTEKWKKLVNKFKQDVERTEESTKEKSEIVKAGIIKWQEFFNNNLGKDVIIPSKRSP
                     FAVALNDFKEYEKMLEEEKEKFTGDFLLSRYDALKVIKRLQENWTDIGFGILSRHKSM
                     DGLLPPEHEYMEDIVKIISKLYREYEIRINGDNGISKVLPNLVISLDMCVFKLENFLD
                     YSQVPTEEWLEIDEKINEMKFHLEALLNIIDSVPEGMDMEPGAALLEHICEMIQQWLL
                     KLGNEITNGQIELLRHMDEMHIAMIQWMVNLLTIMLPDFTDQDILPKREESSLETPEE
                     HEIGIAELEINAIALVKRLARYSSYLHSCCIGMVRAMALSRAAHLQKNPAKDRQDLER
                     MNRECYDWISTCSHLISDIKGRKIRLLSYEEAEKLLGEEEASKLYFDPEKPPIDDDTD
                     DEIDFKKPKFQEKEAPLPAAAEAEAIEATEAAGAATAEATGAAETATAEATGPATAEA
                     AGAAGAATAEATEAAGAATAEATGAAGAKVTTEQGPSPSTNEKTIRYIKKDENIHCKP
                     LFEEGIFFSWREPPSQGVMEPKYLEIMNVIEHMQRKLTEMDTRARKAEERFDEVNEQL
                     HHSLIRNRNLERELEELVKTTMMGSQVKTENAKENQEDRGGKDDDEHQQTQTPPTSAK
                     KEAQPTNSSEAPEDQNTPEPKPN"
     exon            267..439
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            440..543
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            544..658
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            659..744
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            745..801
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            802..904
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1026
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1167
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1272
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1273..1393
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1495
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1659
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1735
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1970
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2172
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2266
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..2475
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2572
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2683
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            2684..3016
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            3017..3118
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            3119..3201
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            3202..3440
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     exon            3441..3736
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3712..3717
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /note="hexamer: ATTAAA"
     polyA_site      3736
                     /gene="Axdnd1"
                     /gene_synonym="9430070O13Rik; Gm979"
                     /note="major polyA site"
ORIGIN      
        1 cgttgctatg acgacgcagg gcgttccgga aaagggatgg ccttccgacg ccaggcggca
       61 aacacaactt aattatggac agcttgaaag tctgaacacg attttgattt gtttttgaat
      121 taattttttg gaggattaat agttctgaga gtgatcccag gcattgatta ttatgtctct
      181 ccacaaagtg tcggacactt cgctgacctc cccatcaaca tctgagtcca aacaggcaaa
      241 actctatgta gtcaaggagg caaaagggct tcctgagcta aaggagaaaa aatccatggt
      301 gaaccacctc aaaccccttc ctccccttca gaatgactac agaatccccg aggaagttct
      361 tctctctctg aactatgcag ctaatgccgg tccctgtcct gaaagcttac tgcctgtgaa
      421 gaaacctaaa gccccaaagt gtgcccttcc acgtcttgta gatcatgtct ggcagcaccc
      481 tattcgaagg gataaattca aatacctgat tgatcatcct gtctccctaa caggagctgg
      541 aagggatatt tctttcctgt atgatgttaa atacgtgaaa ggagaggccg tggagaaaaa
      601 actttgtccc ccaaacaagt caacacagtc acaaagcagt gccatggtgc ctcataagga
      661 gaagacatta gcagacactt tggttcctga ggaatttcat attgtgtcaa atacaggagt
      721 ttcaggtttg gagtgttatg acgacaaata caccaccctc ctcacagaca gtgagaacag
      781 gttgttgctc ttcccatcca tgaaacctaa taaaagagta gaagtggtcc agttgagcaa
      841 cgtgatggac accatgctgg agagggctgg aatagaaaat gagaattatg tagggccaac
      901 caagatgcac cagctgctca acgtgctgaa gagggagcag agcatctaca acacagtgtt
      961 tcatgagctg atccggcagg tcagcgtaga ctgtgcagac agaggagagc tgctgtcaaa
     1021 aatcagagag aagtatgtgc aaatgcttga ccatatcgcc cagcagatga ttgaattcta
     1081 taaagacctg gtgactcagc ggatgatgga ccagcgcatc ttacaagaac tgtataactt
     1141 caagaacgtg attgaagaac tgaccaggga actttgtctg gttcaggccc atgacaggaa
     1201 attaacaaag gaagcagaga aagtccagaa gaacctggca gaagctcttt tggaagcgga
     1261 aaagaatgcc aaaatagtag aagactacca cgacttatac acaatgcaga gaggaaggat
     1321 ggagagtgat attaaactct taatgactga aagagacatt tggagctcag ccacatatga
     1381 actagccctg aaggtaattg aaagaaatag agtcatactg gctaaaaaac tctaccttag
     1441 tgagaaaggc tggaataaat atgctaagca tttcattata atgctgtcaa ctaaggacac
     1501 tggagacctt gggatggtgg agaagttgac agaaaaatgg aaaaagctag tgaacaagtt
     1561 taagcaggat gtggaacgca cggaggaatc cacaaaagaa aaatcagaaa ttgtgaaggc
     1621 tgggatcatc aagtggcagg aattcttcaa taacaacctt ggaaaagatg ttataatccc
     1681 tagtaagaga agcccattcg ccgtagccct taatgacttc aaggagtatg aaaagatgct
     1741 ggaggaggag aaagagaagt ttacagggga ttttcttttg tccagatatg atgctctcaa
     1801 agtgattaaa cgcttacagg aaaactggac agatatcggg tttgggatac tgagtcgcca
     1861 taaaagtatg gatgggttgt tgccaccaga gcacgagtac atggaagata ttgtaaaaat
     1921 cataagcaag ctctacagag aatatgaaat aagaataaac ggtgacaatg gtatctctaa
     1981 agttcttcca aacttggtca tttctttgga catgtgtgtt ttcaagttag aaaacttcct
     2041 tgattattct caagtaccca ctgaagagtg gcttgaaatt gatgaaaaga ttaatgaaat
     2101 gaagtttcat ctggaagcgc tgttgaacat tattgattcg gttccagagg gcatggacat
     2161 ggaacctggc gcggcactcc tagaacatat atgtgaaatg attcaacaat ggctcttgaa
     2221 gttaggcaac gaaatcacca atggtcaaat tgaacttctt cgccacatgg atgagatgca
     2281 tatagctatg atccagtgga tggtaaattt gctgaccata atgcttcctg actttaccga
     2341 ccaagacatt ctcccgaaga gggaggagag cagcttagag acccctgagg agcatgaaat
     2401 aggcatcgca gagttagaga taaacgcaat tgcactggtc aagcggttgg cacgatactc
     2461 cagctacttg cacagttgct gtataggcat ggtaagagca atggccctga gtagagctgc
     2521 tcacttacag aagaatcctg ctaaggaccg tcaggacctg gaaaggatga atagagaatg
     2581 ttatgattgg atcagcacat gttcacacct catttctgat atcaaaggca ggaaaatacg
     2641 attactgtca tatgaggaag cagagaagct gctcggggaa gaggaagctt caaaacttta
     2701 ttttgaccca gaaaaacctc ctattgatga tgataccgat gatgaaattg actttaagaa
     2761 gcctaagttt caagaaaagg aagcaccatt gccagcagca gcagaagcag aggcaataga
     2821 agcaacagag gcagcaggag cagcaacagc agaagcaaca ggagcagcag aaacagcaac
     2881 agcagaagca acaggaccag caacagcaga agcagcagga gcagcaggag cagcaacagc
     2941 agaagcaaca gaagcagcag gagcagcaac agcagaagca acaggagcag caggagcaaa
     3001 agtcacaaca gaacagggac cttcgccatc tacaaatgag aaaaccattc gatacattaa
     3061 gaaagatgaa aatattcatt gcaaacctct cttcgaagaa ggcatatttt tctcctggag
     3121 agaaccacct agtcaaggtg taatggagcc aaagtatctt gaaataatga atgtaattga
     3181 gcatatgcag aggaagctaa cagagatgga caccagggcc aggaaggcag aggagaggtt
     3241 tgatgaggta aacgagcagc ttcatcacag cctcataaga aacagaaacc tggagaggga
     3301 gctagaagaa ttggtgaaga caaccatgat ggggtcacaa gtgaagacag aaaatgccaa
     3361 agagaaccag gaggaccgtg ggggaaagga tgatgatgaa caccaacaaa cacaaacgcc
     3421 cccaacatct gccaagaaag aagcacagcc cacgaacagt tctgaagcac ctgaagatca
     3481 gaatacacct gagcccaaac ccaattagcc tccctagaga gtggggctca cagtgcctgt
     3541 gtccctgaag acgcctgagt attgctgagc tgtcgcattg gcaacacagc tcacatggat
     3601 ggactcgcat agcaacaggc attaggaaag ccatgccatc aagccaagaa aatttctctc
     3661 tagaagcatg gcagaagcca taggaagtca gtatatgagt ttacttgcta gattaaaaac
     3721 agcttatgag aaagga
//
