LOCUS       NM_001289545            2458 bp    mRNA    linear   ROD 28-MAY-2024
DEFINITION  Mus musculus ataxin 7-like 2 (Atxn7l2), transcript variant 1, mRNA.
ACCESSION   NM_001289545 XM_006502135
VERSION     NM_001289545.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2458)
  AUTHORS   Raja,R., Dumontier,E., Phen,A. and Cloutier,J.F.
  TITLE     Insertion of a neomycin selection cassette in the Amigo1 locus
            alters gene expression in the olfactory epithelium leading to
            region-specific defects in olfactory receptor neuron development
  JOURNAL   Genesis 62 (2), e23594 (2024)
   PUBMED   38590146
REFERENCE   2  (bases 1 to 2458)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2458)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Kitamura,H., Nakagawa,T., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of FLJ
            genes: the complete nucleotide sequences of 110 mouse
            FLJ-homologous cDnas identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (2), 127-135 (2004)
   PUBMED   15449545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL671854.14.
            
            On Dec 23, 2021 this sequence version replaced NM_001289545.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094547.1, SRR7652917.3292.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               AL671854.14        153721-153903       c
            184-249             AL671854.14        151816-151881       c
            250-354             AL671854.14        151339-151443       c
            355-565             AL671854.14        150770-150980       c
            566-852             AL671854.14        150199-150485       c
            853-935             AL671854.14        149602-149684       c
            936-1189            AL671854.14        149008-149261       c
            1190-1388           AL671854.14        148092-148290       c
            1389-1510           AL671854.14        147877-147998       c
            1511-2306           AL671854.14        146624-147419       c
            2307-2458           AL671854.14        145598-145749       c
FEATURES             Location/Qualifiers
     source          1..2458
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 46.87 cM"
     gene            1..2458
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /note="ataxin 7-like 2"
                     /db_xref="GeneID:72522"
                     /db_xref="MGI:MGI:1919772"
     exon            1..183
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..2321
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     mFLJ00381 protein"
                     /codon_start=1
                     /product="ataxin-7-like protein 2 isoform 1"
                     /protein_id="NP_001276474.1"
                     /db_xref="GeneID:72522"
                     /db_xref="MGI:MGI:1919772"
                     /translation="MAVRERAVAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGA
                     ELEENSKNTKKLDAMTLIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERR
                     HGPLSKLYARAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQP
                     PEKTQKDSLCLFVPVVNLEKISSLPKPDAHGVRVAPPSALLSQPGGLPKDSPGKVPTA
                     PSPKEPPGRENIELVPGEGSSHRAEGSPPEKEASGARLPPKTHRKMARKEFDLNRQCG
                     VINPETKKICTRLLTCKIHSVHQRREVPGRAKDFDVLVAELKASSRKGESPKEKSPAH
                     KEPALERPSQEPPTAVQGVAAVAAPNTTFSSLSKQTYPYCALPRSHASSESEVDDEGP
                     CGGDGDPGLFPFPLPRGGAQASSEESEEEGISDDLHLSPDCHYATRPPRPQAFCTFGS
                     RLVSPGCYVFSRRLDRFCSALSSMLERHLSSHMWKKIPPAAEPPSHLVSPSLSDPLSP
                     SPMGSCPRLPGPAPRPACPASIPPVKDSLVPSYPAGSPSVAAACSQAECMGGSQAITS
                     PLPANTPSPSFSKLPPSKASKSSKGKEGVEMEAPSRKRKLSPGPTTFKRTCILEPAGK
                     GKPSSCRGLSTKTKTALNLGLNGTVGPRVKRAGPLDCRGSPHPSPIPVKASQLENRGV
                     AGHPAKVLPTTCLSEEEVAKKRKNLATYCRPVKAKHCQAGVPPDGTCSVRRKKPGPAL
                     PFEEKCSTLKSKAH"
     exon            184..249
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            250..354
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            355..565
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            566..852
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            853..935
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1189
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1388
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1510
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..2306
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2458
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2426..2431
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      2458
                     /gene="Atxn7l2"
                     /gene_synonym="2610528J18Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggggggaggg ggccgcgcgg cggcggcgcc agggcgggcg cgcgtccgcg gcggtgatgg
       61 cggtgcgtga acgcgcggtg gcagcaatgg ccgctctgga gcggcgagtg ccgagtctcg
      121 atgacttcgc gggacagagc tggagctcgt gggtggagcg ggccgacctg cctgcggcag
      181 acggggctga actagaggag aacagcaaaa acacgaagaa acttgacgcc atgaccctca
      241 ttaaagaaga catgtccatc ttcgggcact gccctgccca tgatgacttc tatttggttg
      301 tatgtaacca ctgcagccag gtggtgaagc cccaagcctt ccagaagcat tgcgaaagaa
      361 gacatgggcc cctcagcaag ctttatgccc gggccccacc cccacctcca gcccctgcca
      421 gctctcaaaa atgccatgta gtgaatgggc agggcccagc ttgtagagcc ccaggttcca
      481 ccaaaacctc ctccagggag aagggccagg ggtcccggag ccgtggccat cagcctcctg
      541 agaagaccca gaaggacagc ctctgccttt tcgtgcctgt ggtgaatctg gagaagatat
      601 ccagtctccc gaaacctgat gcacatggag tcagggtggc cccaccctct gctctcctca
      661 gtcagccagg aggcctcccc aaggactccc ctggaaaagt ccccacggcc ccctctccta
      721 aagaacctcc tggcagagag aacatcgagc ttgtccccgg tgagggctcc agtcaccgcg
      781 ccgaaggcag ccccccggag aaggaggcca gtggagccag gcttcctcct aaaacccacc
      841 gaaagatggc tcggaaggag ttcgacctca acaggcagtg cggggtcata aatccagaga
      901 ccaagaagat ctgtacacgc ctattgactt gcaagatcca ctcagtgcac cagcgcaggg
      961 aggtcccagg cagggccaag gactttgatg tgctagtggc cgaactgaag gccagctccc
     1021 gaaaaggaga gtctcccaag gagaagagcc cagcacacaa agagccagct ctggagcgcc
     1081 catcccagga gcctcccact gcagtccagg gtgtggcagc ggtagctgcc cccaacacca
     1141 ccttctcttc tctgtctaag cagacctatc cgtactgtgc actccccagg tcccatgcct
     1201 cctctgagag tgaggtggat gacgaaggtc cctgtggtgg tgatggggat ccaggcctat
     1261 tccccttccc tctgccccgg ggtggggccc aggcctccag tgaggagagt gaggaggagg
     1321 ggatatctga tgacctccac ctttcccctg actgccatta cgcaactcgg ccccccaggc
     1381 cacaggcgtt ttgcacattt ggaagccggc tggtgagccc aggatgctat gtgtttagcc
     1441 gccggctgga ccggttttgc tcagcactca gctccatgct ggaacggcat ctcagctcac
     1501 acatgtggaa gaaaatccca ccagcagccg agcctccatc ccatcttgtc agtccatctt
     1561 tatctgatcc cttgagtcca tcccctatgg gcagctgtcc ccgacttcca ggtccagccc
     1621 cccgacctgc ctgtccagcc tccatacccc ccgtcaagga cagccttgtc cctagctatc
     1681 ctgcaggctc ccccagtgta gcagctgcct gcagccaggc agagtgcatg ggcggtagcc
     1741 aggctattac ctcaccgctg cctgccaaca ctccatctcc gtccttcagc aagctgccac
     1801 cttccaaggc cagcaagtca tccaaaggca aggagggggt ggagatggag gccccttctc
     1861 gaaagcggaa gttatcccct ggccccacca ccttcaaacg gacctgcatc ctggagcctg
     1921 ctggaaaggg caaaccctct agctgtcggg gtctctcaac caagactaaa acagccctga
     1981 acttggggct taatggaaca gtggggccac gagtgaaacg ggccggtccc ctggactgtc
     2041 ggggttcccc tcatccatcc cccatacccg tcaaggcttc tcagctagaa aaccgaggag
     2101 tggccggaca cccagctaag gtcctgccaa ccacctgcct ctccgaggag gaggtagcca
     2161 agaagcggaa aaacctggcc acttactgcc ggccagtcaa ggccaagcac tgtcaggctg
     2221 gtgtccctcc tgatgggacc tgctctgtgc gtcgcaagaa gccaggtcca gccctgccct
     2281 ttgaggagaa gtgctctaca ctgaagtcaa aagctcatta acgagaaagt gcctgcccac
     2341 tgcaacggag ccgccagcac ctcctcccct ccagatctgg gccccaggct gctgccgctt
     2401 tttataactt tatattattt tttttaagaa aaaaaaaaaa ctctttaaaa tacctcaa
//
