LOCUS       NM_001361487            4664 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus ataxin 2-like (Atxn2l), transcript variant 3, mRNA.
ACCESSION   NM_001361487
VERSION     NM_001361487.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4664)
  AUTHORS   Key,J., Harter,P.N., Sen,N.E., Gradhand,E., Auburger,G. and
            Gispert,S.
  TITLE     Mid-Gestation lethality of Atxn2l-Ablated Mice
  JOURNAL   Int J Mol Sci 21 (14), 5124 (2020)
   PUBMED   32698485
  REMARK    GeneRIF: Mid-Gestation lethality of Atxn2l-Ablated Mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4664)
  AUTHORS   Li,Q., Li,T., Xiao,X., Ahmad,D.W., Zhang,N., Li,H., Chen,Z., Hou,J.
            and Liao,M.
  TITLE     Specific expression and alternative splicing of mouse genes during
            spermatogenesis
  JOURNAL   Mol Omics 16 (3), 258-267 (2020)
   PUBMED   32211685
  REMARK    GeneRIF: Specific expression and alternative splicing of mouse
            genes during spermatogenesis.
REFERENCE   3  (bases 1 to 4664)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125322.4.
            
            On Jan 6, 2023 this sequence version replaced NM_001361487.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK155062.1, SRR13862062.40905.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-771               AC125322.4         161457-162227       c
            772-808             AC125322.4         159979-160015       c
            809-865             AC125322.4         159813-159869       c
            866-937             AC125322.4         159660-159731       c
            938-1088            AC125322.4         159280-159430       c
            1089-1213           AC125322.4         158686-158810       c
            1214-1305           AC125322.4         157707-157798       c
            1306-1506           AC125322.4         156662-156862       c
            1507-1682           AC125322.4         156050-156225       c
            1683-1793           AC125322.4         155811-155921       c
            1794-1985           AC125322.4         154994-155185       c
            1986-2057           AC125322.4         154846-154917       c
            2058-2128           AC125322.4         154378-154448       c
            2129-2424           AC125322.4         153917-154212       c
            2425-2494           AC125322.4         153757-153826       c
            2495-2641           AC125322.4         153134-153280       c
            2642-2714           AC125322.4         152977-153049       c
            2715-2905           AC125322.4         152696-152886       c
            2906-3035           AC125322.4         152318-152447       c
            3036-3157           AC125322.4         152110-152231       c
            3158-3370           AC125322.4         151721-151933       c
            3371-4664           AC125322.4         150265-151558       c
FEATURES             Location/Qualifiers
     source          1..4664
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.09 cM"
     gene            1..4664
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /note="ataxin 2-like"
                     /db_xref="GeneID:233871"
                     /db_xref="MGI:MGI:2446242"
     exon            1..771
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             479..3703
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /note="isoform 3 is encoded by transcript variant 3;
                     ataxin 2 related protein; ataxin-2-like protein"
                     /codon_start=1
                     /product="ataxin-2-like protein isoform 3"
                     /protein_id="NP_001348416.1"
                     /db_xref="GeneID:233871"
                     /db_xref="MGI:MGI:2446242"
                     /translation="MLKPQPPQQTSQPQQPPPTQQAVARRSPGGTSPPNGGLPGPLTA
                     TAAPPGPPAAVSPCLGPAAAAGSGLRRGAESILAASAPPQHQERPGAVAIGSVRGQTT
                     GKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDA
                     VHRKASEPAGGPRREDIVDTMVFKPSDVLLVHFRNVDFNYATKDKFTDSAIAMNSKVN
                     GEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYT
                     VPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSG
                     RESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP
                     GSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAVGRMYPPRSPKS
                     AAPAPVSASCPEPPIGSAVASSASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPT
                     KEPSRNLEAQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPETGLDPFPS
                     RILKEEAKGKEKEVDGLLTSDPMGSPVSSKTESILDKEDKVPMAGVGGTEGPEQLPAP
                     CPSQTGSPPVGLIKGDEKEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP
                     GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK
                     YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAAGPPLVAATPYSSYIPYNPQQFPGQPA
                     MMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPAAEQPTPQALYATVH
                     QSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP
                     GALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQAHVQTGVT
                     AAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQGEQ
                     PGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGD"
     exon            772..808
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            809..865
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            866..937
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1088
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1213
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1214..1305
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1506
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1507..1682
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..1793
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..1985
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..2057
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2128
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2424
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2425..2494
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2641
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2642..2714
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2715..2905
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2906..3035
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3036..3157
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3158..3370
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     exon            3371..4664
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4642..4647
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /note="hexamer: AATAAA"
     polyA_site      4664
                     /gene="Atxn2l"
                     /gene_synonym="A2D; A2LG; A2lp; A2RP; Atxnl2"
                     /note="major polyA site"
ORIGIN      
        1 accctcgttg tgaagcaacc gcggccgcca gcatttaagg tggctcagaa cctagaggtg
       61 cgctaagcgc ctgcgcggct ccttttccgc cccaggggct aggccggtcg gagccacggc
      121 tcgagcctct cctctgttcc ggaactaacc gcctggcggc gctccccgcg cccctccccc
      181 gccggcgctt ccgcccgcgc tcctccctct ccttctccag cgacgcgcac gcgcgccagg
      241 ccggctcgcg ccctctcgct gtccaccggc ccgcgagatc ccccctcccc ttccgcctcg
      301 cggcgcttcc tcgcgccgcc gtcttctcga tccacccctg acaccgcggg gctccccccg
      361 cccgccaacg gcgggtcccc tgcttggcga tctctttcgc ttcccgcgct ctccagcagg
      421 ggcccggccc caggccctct ttcccttccc tcttatttct cttccggacg ctgccatcat
      481 gttgaagcct cagccgccac aacagacctc ccaaccccag cagccgcccc ccacgcaaca
      541 ggccgtggct cgccggtctc ccggcgggac cagccctccc aacggcggcc tcccgggacc
      601 gctgaccgcc accgcggctc ccccggggcc tcccgcagcg gtctctccgt gcctggggcc
      661 tgcagccgct gccggcagcg gacttcgccg cggagccgaa agcatcttag cggcgtcagc
      721 gccgccgcag catcaagaaa ggccaggggc agtggctatc ggcagcgtca ggggacagac
      781 caccggaaag ggacccccac agtcacccgt gtttgaaggt gtctataaca attccaggat
      841 gctgcatttc ctgacagctg tagtgggttc tacttgtgac gtaaaggtga aaaatggcac
      901 cacttacgag ggcattttca agactctgag ctcaaagttt gaactggcag ttgacgcggt
      961 gcatcggaaa gcatctgagc cagcaggtgg gcctcgccgg gaagacattg tggacaccat
     1021 ggtgtttaaa ccaagcgacg ttctgcttgt ccacttccga aatgttgact tcaattatgc
     1081 tactaaagat aagttcactg actcagccat tgccatgaac tctaaggtga atggagaaca
     1141 caaagagaag gtgcttcaac gttgggaggg cggtgacagc aacagtgacg actacgatct
     1201 ggaatccgat atgtctaatg gatgggatcc caatgagatg ttcaaattta atgaggagaa
     1261 ctatggagtg aagaccacct atgacagcag tctatcttct tacacggttc ccttagaaaa
     1321 ggacaactct gaagagtttc ggcagcggga gcttcgagcg gcccagttgg ctcgagagat
     1381 tgagtctagt ccccagtacc gcctacggat tgctatggaa aatgacgatg ggagaacaga
     1441 ggaggagaag cacagtgctg ttcagcggca ggggtctggg cgggagagcc ccagcttggt
     1501 atccagggag gggaagtata tccccctgcc tcagcgagtt cgagaaggtc cccggggagg
     1561 agttcgatgc agcagttctc gaggagggcg ccctggcctt agctctttgc cacctcgtgg
     1621 ccctcaccat cttgacaaca gcagtcctgg ccctgggtct gaggcacgtg gtatcaatgg
     1681 aggtccttcc cgcatgtccc ccaaggcaca gcggcctctg agaggtgcca agaccttatc
     1741 ttcacccagc aataggcctt ctggagaagc ttctgttcct ccaacatctg cagtgggccg
     1801 gatgtaccct ccacggtctc ccaagtctgc tgcccctgcc ccagtctcag cttcctgtcc
     1861 tgagcctccc attggttcgg cagtggcgtc ctctgcctcc atccctgtga catcatcagt
     1921 tgtggatcct ggtgcaggct ctatttcccc ggcatctcca aaactctccc tgacccctac
     1981 agatgtaaaa gaactcccaa ccaaggagcc cagtaggaat ttggaagccc aagaactggc
     2041 ccgcatagct gggaaagtcc ctggccttca gaatgaacaa aaacgatttc agttggaaga
     2101 actgagaaaa tttggggccc agtttaagct tcaacctagt agctcccctg agacgggcct
     2161 ggatccattt ccttcccgga tcttgaaaga agaggccaaa ggaaaggaga aagaggtgga
     2221 tggtctattg acttcagatc ctatgggatc cccagtctcc tctaagacag aatccatatt
     2281 ggataaggaa gacaaagtgc ccatggcagg agtaggaggg actgaggggc cagagcagct
     2341 cccagcacct tgtcccagcc aaaccggcag tcctccagtg ggcctcatca agggggatga
     2401 gaaagaggag ggccctgtta ctgaacaagt gaagaagtct actttgaacc ccaacgccaa
     2461 ggagttcaat ccaacaaaac ctctgctgtc tgtgaacaaa tctaccagta ctccaacttc
     2521 accagggccc cgtactcatt caacaccttc tataccggtg ctgacagcag gccagagtgg
     2581 gctctacagt ccccagtaca tctcatatat acctcagatc cacatgggac cagctgtaca
     2641 ggcgcctcag atgtatccat atcctgtatc caattccgtg cctgggcagc agggcaagta
     2701 ccggggtgca aaaggctcac ttcctcctca gcgctctgac caacaccaac cagcctcagc
     2761 ccctccaatg atgcaggctg ctgctgctgc tgctggccca cccctggtgg ctgccacacc
     2821 ctattcctcc tacatcccct acaacccaca gcagttccca ggccagcctg ccatgatgca
     2881 gcccatggca cactaccctt cacagccggt gttcgcccct atgcttcaaa gtaatccacg
     2941 aatgttgaca tcgggaagcc atccccaggc catcgtgtcg tcctccactc ctcagtaccc
     3001 tgctgcagag cagcctaccc cccaagccct ctatgccact gttcaccaat cctatccaca
     3061 ccatgccacg cagctccatg gccaccagcc gcagccggcc accacaccta ctgggagcca
     3121 gccacaatcc cagcatgcgg cccccagtcc cgttcagcac caggcggggc aggcccctca
     3181 cctgggcagt ggacagccac agcagaatct gtaccatcca ggggccctaa caggcacgcc
     3241 accttctcta ccaccgggac cttctgccca gtcccctcaa agcagcttcc cccagccagc
     3301 tgctgtgtat gccatccatc cccaccagca gctgccccac ggcttcacca acatggccca
     3361 tgttacccag gcccatgtcc aaactggagt cacagcagcc ccgcccccac accctggggc
     3421 tccccacccg ccccaggtga tgctgctgca ccccccccag ggccatgggg ggccccccca
     3481 aggcgcggtg cccccgagtg gggtgcctgc actctcagct tccacaccct caccctaccc
     3541 ctacatcgga cacccccaag gtgagcagcc tggccaggcg cctggatttc caggaggagc
     3601 cgatgacagg attcgtgagt tctcgttagc tgggggaatt tggcatggaa gagctgaggg
     3661 gctgcaggtg gggcaggatg cacgggttct gggtggggat tgaggggtct tggaggcagg
     3721 gctgtcccag agggcgcccg ccgacccaca cctgtctgtg aagtatgtag ggtgggcaga
     3781 agccacagtc gccgccgcca ggggcttgct cctggctctg tcctttgctt ccctccgtcc
     3841 tcgctcagtt gtgatccagc agcccccctc cccactgcct ccccagctct cagtgacccc
     3901 gactgtctcc tgacttagcc gaggtaaggt cagcgcagca gacagggcca gactggggcg
     3961 tggggggctg agctgggcaa ctgagtaagg gctctggcct actgggaaac agcgattgac
     4021 ctgtgcttct gacagtcccc tgagactcct cgaggaggcc gctcctcccc acacccctca
     4081 ccccctggac gcattgacag agggacagct gctcgggttc taatgctcct gctctctctc
     4141 tttcccctcc aaccagttca atctcatccc tcccagcagc tccccttcca ccccccgggg
     4201 aactgaagat tgtcctggcc gcgacctgag acctccatga gtggagggaa gagtgatcta
     4261 tgtctcttcc ccccagcagc tgggaccagt cctagccccg tccccaaccc ctttcccttg
     4321 gggagttggg ggaattcctg ccaagcacct tgaatgggag gggtccttca agtgggccgg
     4381 gctggggtcc aacgggggtg ggggaggttc ctgctctgcc ccagctgggt cctacccagt
     4441 cttgtcctcc catcctctca tctattcccc cccgccccct ggagacggaa gatcttttat
     4501 tttctattat ttataacctc agacttgggc cccctgttct tctccattaa cttgagtgtt
     4561 ctgtgtgaga ccaacagaca gatgcctcaa ggacttttac tttttattac ataaaaaaat
     4621 taaaaaaaaa taaaataaaa aaataaaatt ttaaactaac ttaa
//
