LOCUS       NM_027855                971 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus all-trans retinoic acid induced differentiation factor
            (Atraid), transcript variant 1, mRNA.
ACCESSION   NM_027855 XM_355589
VERSION     NM_027855.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 971)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 971)
  AUTHORS   Surface,L.E., Burrow,D.T., Li,J., Park,J., Kumar,S., Lyu,C.,
            Song,N., Yu,Z., Rajagopal,A., Bae,Y., Lee,B.H., Mumm,S., Gu,C.C.,
            Baker,J.C., Mohseni,M., Sum,M., Huskey,M., Duan,S., Bijanki,V.N.,
            Civitelli,R., Gardner,M.J., McAndrew,C.M., Ricci,W.M.,
            Gurnett,C.A., Diemer,K., Wan,F., Costantino,C.L., Shannon,K.M.,
            Raje,N., Dodson,T.B., Haber,D.A., Carette,J.E., Varadarajan,M.,
            Brummelkamp,T.R., Birsoy,K., Sabatini,D.M., Haller,G. and
            Peterson,T.R.
  TITLE     ATRAID regulates the action of nitrogen-containing bisphosphonates
            on bone
  JOURNAL   Sci Transl Med 12 (544) (2020)
   PUBMED   32434850
REFERENCE   3  (bases 1 to 971)
  AUTHORS   Yu,Z., Surface,L.E., Park,C.Y., Horlbeck,M.A., Wyant,G.A.,
            Abu-Remaileh,M., Peterson,T.R., Sabatini,D.M., Weissman,J.S. and
            O'Shea,E.K.
  TITLE     Identification of a transporter complex responsible for the
            cytosolic entry of nitrogen-containing bisphosphonates
  JOURNAL   Elife 7, e36620 (2018)
   PUBMED   29745899
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 971)
  AUTHORS   Ding,X., Chen,Y., Han,L., Qiu,W., Gu,X. and Zhang,H.
  TITLE     Apoptosis related protein 3 is a lysosomal membrane protein
  JOURNAL   Biochem Biophys Res Commun 460 (4), 915-922 (2015)
   PUBMED   25839652
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY033481.1, BC057097.1 and AW987473.1.
            
            On Nov 6, 2013 this sequence version replaced NM_027855.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK151307.1, AK151366.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                BY033481.1         1-27
            28-961              BC057097.1         1-934
            962-971             AW987473.1         4-13                c
FEATURES             Location/Qualifiers
     source          1..971
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 16.94 cM"
     gene            1..971
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /note="all-trans retinoic acid induced differentiation
                     factor"
                     /db_xref="GeneID:381629"
                     /db_xref="MGI:MGI:1918918"
     exon            1..117
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..705
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; apoptosis related protein APR-3; H1E6 protein"
                     /codon_start=1
                     /product="all-trans retinoic acid-induced differentiation
                     factor isoform 1 precursor"
                     /protein_id="NP_082131.2"
                     /db_xref="CCDS:CCDS19170.1"
                     /db_xref="GeneID:381629"
                     /db_xref="MGI:MGI:1918918"
                     /translation="MASRESGGSRAAALLLVLGVERALALPEICTLCPGGMHNLSRVA
                     AYCEDTSKLMQARCCLNQKGTILGLDLQNCSLKDPGPNFLQAYTAIIIDLQANPLKDD
                     LANTFRGFTQLQTLILPQDVPCPGGSNAWDNVTSFKDKQICQGQRDLCNSTGSPEMCP
                     ENGSCASDGPGLLQCVCADGFHGYKCMRQGSFSLLMFFGILGSTTLAISILLWGTQRR
                     KAKAS"
     exon            118..236
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /inference="alignment:Splign:2.1.0"
     exon            237..308
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /inference="alignment:Splign:2.1.0"
     exon            309..380
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /inference="alignment:Splign:2.1.0"
     exon            381..502
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /inference="alignment:Splign:2.1.0"
     exon            503..600
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /inference="alignment:Splign:2.1.0"
     exon            601..971
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      932..937
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /note="hexamer: AATAAA"
     polyA_site      961
                     /gene="Atraid"
                     /gene_synonym="0610007C21Rik; Apr3; HSPC013; p18"
                     /note="major polyA site"
ORIGIN      
        1 gcgagctgtc aagacggtgg aaagcagtgg gaaatggcgt ctcgggagtc aggcggctct
       61 cgggcggccg ccctgctcct ggttctgggc gtggagaggg ccctggctct acctgagata
      121 tgcaccctgt gtccgggagg tatgcacaat ttgtccagag tggctgctta ctgtgaggat
      181 acatcgaagc taatgcaggc ccgatgctgc ctgaatcaga agggcaccat cttggggcta
      241 gatcttcaga actgttccct gaaggatcct ggtccaaact ttttacaggc ttatactgct
      301 attatcatag accttcaggc aaatcctctc aaggatgatt tggccaacac cttccgtggg
      361 tttactcagc tgcagactct gatactacca caagatgttc cctgtcctgg aggtagtaat
      421 gcctgggaca atgttacttc tttcaaggac aagcagattt gccaagggca aagggacctt
      481 tgcaatagca ctggaagccc agaaatgtgt cctgagaacg gatcttgtgc atctgacggt
      541 cctggtcttt tgcagtgcgt ttgtgctgat ggtttccatg gatacaagtg tatgaggcag
      601 ggctcatttt cactgcttat gttctttggg attctgggat ccaccacgct agccatctcc
      661 attctacttt ggggaaccca gcgccggaaa gccaaggctt catgagccac acaagacttc
      721 cagctcacct gactgcgcac cctcatctat caagtcccgg ccatgtcgca gccaagaaga
      781 tttacttcgt tgacaattac tggccaatga gcagaactgt ttaaggctga agcggccatt
      841 gataatgaaa ggtgtcaaat tgcaccacct cgggggtctt gtggacactt ggttcaggag
      901 tggactcgta ctaatttgta ttattgacta caataaacac cttttccccc gttttagaga
      961 atgctgccgt a
//
