LOCUS       NM_001408887            1943 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ATP synthase mitochondrial F1 complex assembly factor
            2 (Atpaf2), transcript variant 14, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001408887
VERSION     NM_001408887.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1943)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1943)
  AUTHORS   Lin,W., Qiao,C., Hu,J., Wei,Q. and Xu,T.
  TITLE     Conserved role of ATP synthase in mammalian cilia
  JOURNAL   Exp Cell Res 401 (1), 112520 (2021)
   PUBMED   33639177
  REMARK    GeneRIF: Conserved role of ATP synthase in mammalian cilia.
REFERENCE   3  (bases 1 to 1943)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1943)
  AUTHORS   Ricard,G., Molina,J., Chrast,J., Gu,W., Gheldof,N., Pradervand,S.,
            Schutz,F., Young,J.I., Lupski,J.R., Reymond,A. and Walz,K.
  TITLE     Phenotypic consequences of copy number variation: insights from
            Smith-Magenis and Potocki-Lupski syndrome mouse models
  JOURNAL   PLoS Biol 8 (11), e1000543 (2010)
   PUBMED   21124890
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1943)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596090.11.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12282455.14333827.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-283               AL596090.11        139179-139461       c
            284-429             AL596090.11        138260-138405       c
            430-474             AL596090.11        131095-131139       c
            475-620             AL596090.11        130769-130914       c
            621-718             AL596090.11        128803-128900       c
            719-799             AL596090.11        127285-127365       c
            800-912             AL596090.11        125889-126001       c
            913-1028            AL596090.11        125346-125461       c
            1029-1943           AL596090.11        122133-123047       c
FEATURES             Location/Qualifiers
     source          1..1943
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.81 cM"
     gene            1..1943
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="ATP synthase mitochondrial F1 complex assembly
                     factor 2"
                     /db_xref="GeneID:246782"
                     /db_xref="MGI:MGI:2180561"
     exon            1..283
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            284..429
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            430..474
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            475..620
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            621..718
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            719..799
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            800..912
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1028
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1943
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1501..1506
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="hexamer: ATTAAA"
     polyA_site      1527
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="major polyA site"
     regulatory      1918..1923
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="hexamer: AATAAA"
     polyA_site      1943
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="major polyA site"
ORIGIN      
        1 agtgagaggg cctggtccgc ggctgagggc tcgaggagcc cagggcaggc ccggcccgtg
       61 agcgccgcga ggaggccctc gggcccggcc ttgccgcctg gcgctcacct gcagcaccac
      121 ctctacgtcg tacgagttcc ccttgctctt ctggtggcca cggaacttgg agccgctgta
      181 gagcaagctg gtggccacgc cgggctgctg ggtgttgatg ggcggcggcg ggatgagtga
      241 ggccgcggat gtggttgagg cacccgccgg cgggggacac tcggtccttg ggcaggatgt
      301 ggcgaatcta cccccggctg agggaccggt ggcgcggtct cttggaccgg cgtctcagtg
      361 accccaccgt ctcagtatgg ccggggccag ctccgcagcc tccggcccgg gcctatgtcc
      421 cgccaacaga aaggaagagg ttttatcaga atgtcagcat ctcacagggt gaaggtggct
      481 ttgagataaa cctggaccac agaaagctga aaactcccca agccaagctt tttactgtcc
      541 ccagcgaagc cctggccatc gcagtggcca ctgaatggga ctctcagcag gataccatca
      601 agttctacac catgcacctg accacattgt gcaacacatc cttggacaac ccaacccagc
      661 gaagtaaaga ccagctgatc cgggcagctg tgaagtttct agacactgac accatctgct
      721 acagggtgga agagccagag acattagtgg aacttcagaa gaacgaatgg gatcccgtca
      781 tagagtgggc tgagaaaagg tacggtatgg agatcggctc ctccaccagc ataatgggac
      841 ccagcatccc tacccagacc cgagaggtgc ttaccagcca cttgtcctct tacaacatgt
      901 gggctctgca agggattgag tttgtagtgg cccagctcaa atccatgttg ctgactttgg
      961 gcctgattga cttgcgcctg actgtggaac aagctgtgct tctgtcacgc ctggaggaag
     1021 agtaccagat ccagaagtgg ggcaacattg agtgggccca cgactatgag ctccaggagc
     1081 tgcgggctcg cactgctgct ggcacccttt ttgtccacct ctgctcagaa agctctacag
     1141 tcaagcacaa gctccttcaa gagtgaggcc cggggtgcac acgctgtctg gaaggaattg
     1201 cacagacaca ggctccctga tgtgggcctc cttggctgtt ggacctctgg atcctgtgat
     1261 actctgttgg ccggtaccta ctgggctccc tcagccctat acctgtgggg ctccccagcc
     1321 tgtacctggg tcttccctga cctgtgtggt ttgaccttat aaagaagcat cctgagaagc
     1381 cctgaagaca cagtgtgcct gacttgaggt cagatagctt ccgatgcagg cgcccttggt
     1441 ctgaccagaa gtgagggagg aagacaagtg gtatagggac tttctcttga ccctgatttt
     1501 attaaatatt ttttcattct ggaaatatat caagcctcat ttttatttga gccttggcat
     1561 ttctccattc tttttgtttt atctgagctc tgtcaccatt attacatctg ctactaatgg
     1621 ctaggaacct catggggagg gcaggaaaag cacatcgcca catgcaagcc ttttcctgaa
     1681 ggccttccac accccacacc ccatactccc tggcttttca tcaaatgatc ttttaaaagt
     1741 gaatctttgg agggctggag agatggctca gcggttacga gcactgactg ctcttctcaa
     1801 ggtcgtgagt tcaattccca gcagccacat ggtggctcac aaccatctgt aacaagatct
     1861 ggggccctct tctggtgtgt ctgaagacag ctacagtgta cttacatata ataaataaat
     1921 aaatctttta aaaaaaaagt gaa
//
