LOCUS       NM_001408884            1420 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ATP synthase mitochondrial F1 complex assembly factor
            2 (Atpaf2), transcript variant 11, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001408884 XM_011249026
VERSION     NM_001408884.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1420)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1420)
  AUTHORS   Lin,W., Qiao,C., Hu,J., Wei,Q. and Xu,T.
  TITLE     Conserved role of ATP synthase in mammalian cilia
  JOURNAL   Exp Cell Res 401 (1), 112520 (2021)
   PUBMED   33639177
  REMARK    GeneRIF: Conserved role of ATP synthase in mammalian cilia.
REFERENCE   3  (bases 1 to 1420)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1420)
  AUTHORS   Ricard,G., Molina,J., Chrast,J., Gu,W., Gheldof,N., Pradervand,S.,
            Schutz,F., Young,J.I., Lupski,J.R., Reymond,A. and Walz,K.
  TITLE     Phenotypic consequences of copy number variation: insights from
            Smith-Magenis and Potocki-Lupski syndrome mouse models
  JOURNAL   PLoS Biol 8 (11), e1000543 (2010)
   PUBMED   21124890
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1420)
  AUTHORS   Nelson,P.S., Pritchard,C., Abbott,D. and Clegg,N.
  TITLE     The human (PEDB) and mouse (mPEDB) Prostate Expression Databases
  JOURNAL   Nucleic Acids Res 30 (1), 218-220 (2002)
   PUBMED   11752298
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596090.11.
            
            On Jun 30, 2022 this sequence version replaced XM_011249026.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422601.60445.1,
                                           SRR17253013.3048358.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AL596090.11        138495-138546       c
            53-97               AL596090.11        131095-131139       c
            98-195              AL596090.11        128803-128900       c
            196-276             AL596090.11        127285-127365       c
            277-389             AL596090.11        125889-126001       c
            390-505             AL596090.11        125346-125461       c
            506-1420            AL596090.11        122133-123047       c
FEATURES             Location/Qualifiers
     source          1..1420
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 37.81 cM"
     gene            1..1420
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="ATP synthase mitochondrial F1 complex assembly
                     factor 2"
                     /db_xref="GeneID:246782"
                     /db_xref="MGI:MGI:2180561"
     exon            1..52
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            53..97
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..643
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="isoform 3 is encoded by transcript variant 11"
                     /codon_start=1
                     /product="ATP synthase mitochondrial F1 complex assembly
                     factor 2 isoform 3"
                     /protein_id="NP_001395813.1"
                     /db_xref="GeneID:246782"
                     /db_xref="MGI:MGI:2180561"
                     /translation="MSASHRVKTTLCNTSLDNPTQRSKDQLIRAAVKFLDTDTICYRV
                     EEPETLVELQKNEWDPVIEWAEKRYGMEIGSSTSIMGPSIPTQTREVLTSHLSSYNMW
                     ALQGIEFVVAQLKSMLLTLGLIDLRLTVEQAVLLSRLEEEYQIQKWGNIEWAHDYELQ
                     ELRARTAAGTLFVHLCSESSTVKHKLLQE"
     exon            98..195
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            196..276
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            277..389
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            390..505
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     exon            506..1420
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /inference="alignment:Splign:2.1.0"
     regulatory      978..983
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="hexamer: ATTAAA"
     polyA_site      1004
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="major polyA site"
     regulatory      1395..1400
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="hexamer: AATAAA"
     polyA_site      1420
                     /gene="Atpaf2"
                     /gene_synonym="ATP12; ATP12p"
                     /note="major polyA site"
ORIGIN      
        1 gtcatgagga agatggcggc gtgctgagga ggctgagggc tatgaaccct tgaaaggaag
       61 aggttttatc agaatgtcag catctcacag ggtgaagacc acattgtgca acacatcctt
      121 ggacaaccca acccagcgaa gtaaagacca gctgatccgg gcagctgtga agtttctaga
      181 cactgacacc atctgctaca gggtggaaga gccagagaca ttagtggaac ttcagaagaa
      241 cgaatgggat cccgtcatag agtgggctga gaaaaggtac ggtatggaga tcggctcctc
      301 caccagcata atgggaccca gcatccctac ccagacccga gaggtgctta ccagccactt
      361 gtcctcttac aacatgtggg ctctgcaagg gattgagttt gtagtggccc agctcaaatc
      421 catgttgctg actttgggcc tgattgactt gcgcctgact gtggaacaag ctgtgcttct
      481 gtcacgcctg gaggaagagt accagatcca gaagtggggc aacattgagt gggcccacga
      541 ctatgagctc caggagctgc gggctcgcac tgctgctggc accctttttg tccacctctg
      601 ctcagaaagc tctacagtca agcacaagct ccttcaagag tgaggcccgg ggtgcacacg
      661 ctgtctggaa ggaattgcac agacacaggc tccctgatgt gggcctcctt ggctgttgga
      721 cctctggatc ctgtgatact ctgttggccg gtacctactg ggctccctca gccctatacc
      781 tgtggggctc cccagcctgt acctgggtct tccctgacct gtgtggtttg accttataaa
      841 gaagcatcct gagaagccct gaagacacag tgtgcctgac ttgaggtcag atagcttccg
      901 atgcaggcgc ccttggtctg accagaagtg agggaggaag acaagtggta tagggacttt
      961 ctcttgaccc tgattttatt aaatattttt tcattctgga aatatatcaa gcctcatttt
     1021 tatttgagcc ttggcatttc tccattcttt ttgttttatc tgagctctgt caccattatt
     1081 acatctgcta ctaatggcta ggaacctcat ggggagggca ggaaaagcac atcgccacat
     1141 gcaagccttt tcctgaaggc cttccacacc ccacacccca tactccctgg cttttcatca
     1201 aatgatcttt taaaagtgaa tctttggagg gctggagaga tggctcagcg gttacgagca
     1261 ctgactgctc ttctcaaggt cgtgagttca attcccagca gccacatggt ggctcacaac
     1321 catctgtaac aagatctggg gccctcttct ggtgtgtctg aagacagcta cagtgtactt
     1381 acatataata aataaataaa tcttttaaaa aaaaagtgaa
//
