LOCUS       NM_001369233            1747 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ATP synthase mitochondrial F1 complex assembly factor
            1 (Atpaf1), transcript variant 2, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001369233
VERSION     NM_001369233.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Zhou,Z., Zhang,K., Liu,Z., Gao,X., Huang,K., Chen,C., Wang,D.,
            Yang,Q. and Long,Q.
  TITLE     ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial
            respiration
  JOURNAL   Mitochondrion 60, 129-141 (2021)
   PUBMED   34375736
REFERENCE   2  (bases 1 to 1747)
  AUTHORS   Boerries,M., Most,P., Gledhill,J.R., Walker,J.E., Katus,H.A.,
            Koch,W.J., Aebi,U. and Schoenenberger,C.A.
  TITLE     Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an
            increased ATP content in cardiomyocytes
  JOURNAL   Mol Cell Biol 27 (12), 4365-4373 (2007)
   PUBMED   17438143
  REMARK    GeneRIF: Ca(2+)-dependent interaction of SF100A1 with Atpaf1 leads
            to an increased ATP content in cardiomyocytes.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL626806.14.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC044874.1, CO431467.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: PMID: 18614015; reported by
                                                  MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-299               AL626806.14        50662-50960         c
            300-408             AL626806.14        47596-47704         c
            409-459             AL626806.14        45335-45385         c
            460-522             AL626806.14        44681-44743         c
            523-573             AL626806.14        40512-40562         c
            574-621             AL626806.14        39164-39211         c
            622-717             AL626806.14        37905-38000         c
            718-825             AL626806.14        35541-35648         c
            826-1747            AL626806.14        24043-24964         c
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 53.06 cM"
     gene            1..1747
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /note="ATP synthase mitochondrial F1 complex assembly
                     factor 1"
                     /db_xref="GeneID:230649"
                     /db_xref="MGI:MGI:2180560"
     exon            1..299
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..1020
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="ATP synthase mitochondrial F1 complex assembly
                     factor 1 isoform 2"
                     /protein_id="NP_001356162.1"
                     /db_xref="CCDS:CCDS89811.1"
                     /db_xref="GeneID:230649"
                     /db_xref="MGI:MGI:2180560"
                     /translation="MAAVVSAAGGACPAVLQVAGLYRGLCAVRSRALGLGFVSPAQLR
                     VFPVRRGSGLPPEGADGSGVSELEANPFYDRYRDKIQQLRRSDPAAFESRLEKRSEFR
                     KQPVGHSKQSDFIKCMEQKTDALGKQPVSKGFTKDKTLSSVFNVEMVKDKTAEEIKQI
                     WQQYFSAKDTVYAVIPKEKFDLIWNRAQSCPTFLCALPRRDGYEFFVGQWTGTELHFT
                     ALINIQTRGDAAASQLILYHYPELKEEKGIVLMTAEMDSTFLNVVEAQCIANQVQLFY
                     ATDRKEIYGLVETFNFRPNEFKYMSVIAELEQSGLGAELKRAQNQDKT"
     exon            300..408
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     exon            409..459
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     exon            460..522
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     exon            523..573
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     exon            574..621
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     exon            622..717
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     exon            718..825
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
     exon            826..1747
                     /gene="Atpaf1"
                     /gene_synonym="6330547J17Rik; ATP11; ATP11p"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggctgacg cgcccgagga ggaggagggg gagtcgcagg cggccatggc ggcggtagtg
       61 tccgctgcgg gtggagcgtg ccccgcagtc ctgcaggtgg cgggtctcta ccgaggcctg
      121 tgtgcagtgc gcagccgcgc cctggggctg gggttcgtgt caccggcaca gttgcgcgtg
      181 ttcccggtgc gccggggctc gggcctgccc cccgagggag cagacggcag tggggtcagc
      241 gagctggaag cgaacccctt ctacgaccgc taccgggaca agatccagca gctgcgcagg
      301 tctgacccag cggcctttga gtcccgcctg gagaagcgca gtgagttccg aaagcagcca
      361 gtggggcact ccaaacaaag tgattttatc aagtgtatgg agcagaagac agatgccttg
      421 gggaaacagc ctgtgagcaa aggattcact aaggacaaga ctctcagttc agtcttcaac
      481 gttgagatgg tgaaagacaa aactgcggag gaaataaaac agatttggca gcagtatttt
      541 tcagcaaaag acacagtcta cgcagttatt cctaaagaga agtttgattt gatctggaac
      601 agggctcagt cctgcccaac atttctttgt gcactaccaa gaagggatgg ttatgagttc
      661 tttgtaggac aatggacagg tacagagctc cacttcactg cacttataaa tattcagacc
      721 cgaggggatg cagcagccag ccagctgatt ttatatcact atcctgaact taaggaagaa
      781 aagggcatag tgctgatgac agcagaaatg gactccacat ttctgaatgt tgtggaggca
      841 cagtgcatcg ccaatcaggt tcagctcttc tacgccaccg atcggaagga gatctatggg
      901 ctagtagaga cctttaactt cagaccaaat gagttcaaat atatgtctgt catcgctgag
      961 ttggagcaaa gtggacttgg agccgaactg aaacgtgccc agaaccaaga taagacttag
     1021 aggtatctgg attgtctctt cacagtgttg gctcagtcct ggatggcctg aagcccaccc
     1081 acacccttga attccagagc tcagcatctg caacaagcag tctgtaaaga gttactgtgt
     1141 aagcttattg caagaagtga ttgtggacat gagccctaat acttgataca ggaacaaaga
     1201 tatacaatta ctctgataat tacctctcag cataagggtt ccttttcagt gtttctggcc
     1261 tttggaatga gaaatatatc gcttctcggc cttttggcta agatgaagtg tggaatgaga
     1321 aatattcagg gatccacaag actattggct tggttttatt tagtgtaata gtgcagttgc
     1381 attctggcca ttttgacctc atagctccca cttctatgac ttcataaact gtagcaataa
     1441 gcttgaagat cttagagatg ttggctttat atactctttc catgcaccag tgagctggct
     1501 aaaaacataa cccaaaactc ctggccagac tctaatacaa ccagctattc tcatcagaat
     1561 aaagacttgt ggatgcccct tcagagttgc cttcagtgta actcagtgaa ttacgggtat
     1621 acttcaataa acaggttcaa tgcctgtata ctgttaaact gtcgcttatg gccctactcc
     1681 ctgaactctg cctgtgagaa gctgatgaat cactacagtg taaataaaac ctttttctaa
     1741 ggagatc
//
