LOCUS       NM_177397               1887 bp    mRNA    linear   ROD 10-JUN-2024
DEFINITION  Mus musculus ATPase, H+ transporting, lysosomal V1 subunit G3
            (Atp6v1g3), mRNA.
ACCESSION   NM_177397
VERSION     NM_177397.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Golder,Z.J. and Karet Frankl,F.E.
  TITLE     Extra-renal locations of the a4 subunit of H(+)ATPase
  JOURNAL   BMC Cell Biol 17 (1), 27 (2016)
   PUBMED   27368196
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1887)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   3  (bases 1 to 1887)
  AUTHORS   Norgett,E.E., Borthwick,K.J., Al-Lamki,R.S., Su,Y., Smith,A.N. and
            Karet,F.E.
  TITLE     V1 and V0 domains of the human H+-ATPase are linked by an
            interaction between the G and a subunits
  JOURNAL   J Biol Chem 282 (19), 14421-14427 (2007)
   PUBMED   17360703
REFERENCE   4  (bases 1 to 1887)
  AUTHORS   Jouret,F., Auzanneau,C., Debaix,H., Wada,G.H., Pretto,C.,
            Marbaix,E., Karet,F.E., Courtoy,P.J. and Devuyst,O.
  TITLE     Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are
            differentially expressed during nephrogenesis
  JOURNAL   J Am Soc Nephrol 16 (11), 3235-3246 (2005)
   PUBMED   16177003
REFERENCE   5  (bases 1 to 1887)
  AUTHORS   Sun-Wada,G.H., Yoshimizu,T., Imai-Senga,Y., Wada,Y. and Futai,M.
  TITLE     Diversity of mouse proton-translocating ATPase: presence of
            multiple isoforms of the C, d and G subunits
  JOURNAL   Gene 302 (1-2), 147-153 (2003)
   PUBMED   12527205
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC116868.9.
            
            On Nov 17, 2006 this sequence version replaced NM_177397.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK032887.1, AB088359.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               AC116868.9         118383-118492
            111-211             AC116868.9         128311-128411
            212-1887            AC116868.9         132432-134107
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 60.82 cM"
     gene            1..1887
                     /gene="Atp6v1g3"
                     /note="ATPase, H+ transporting, lysosomal V1 subunit G3"
                     /db_xref="GeneID:338375"
                     /db_xref="MGI:MGI:2450548"
     exon            1..110
                     /gene="Atp6v1g3"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..385
                     /gene="Atp6v1g3"
                     /EC_number="7.1.2.2"
                     /note="V-ATPase subunit G 3; V-ATPase 13 kDa subunit 3;
                     vacuolar proton pump subunit G 3; ATPase, H+ transporting,
                     V1 subunit G"
                     /codon_start=1
                     /product="V-type proton ATPase subunit G 3"
                     /protein_id="NP_796371.1"
                     /db_xref="CCDS:CCDS15331.1"
                     /db_xref="GeneID:338375"
                     /db_xref="MGI:MGI:2450548"
                     /translation="MTSQSQGIQQLLQAEKRAKDKLDEAKKRKGKRLRQAKEEAVAET
                     DQYRMQMEKDFRLKQAKIMGSQSHLSDEIEEQTLEKIKELNGSYNKCMESVIKQLLSM
                     VCDMKPEVHVNYRATN"
     exon            111..211
                     /gene="Atp6v1g3"
                     /inference="alignment:Splign:2.1.0"
     exon            212..1887
                     /gene="Atp6v1g3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      442..447
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp6v1g3"
                     /note="hexamer: ATTAAA"
     polyA_site      461
                     /gene="Atp6v1g3"
                     /note="major polyA site"
     regulatory      515..520
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp6v1g3"
                     /note="hexamer: ATTAAA"
     polyA_site      535
                     /gene="Atp6v1g3"
                     /note="major polyA site"
     regulatory      1857..1862
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp6v1g3"
                     /note="hexamer: AATAAA"
     polyA_site      1886
                     /gene="Atp6v1g3"
ORIGIN      
        1 gaagtcacct tccttggagc aagacaccat gaccagccag tctcagggga tccaacagct
       61 cctgcaggca gagaaaaggg ccaaggacaa gctagatgag gcaaagaaaa gaaaaggaaa
      121 gcgactgagg caagctaagg aagaagctgt ggcggagacg gaccagtaca gaatgcagat
      181 ggagaaggac ttccgcctga agcaggctaa gataatgggc tctcagagcc acctctcgga
      241 tgaaatagaa gagcagacac tagagaagat caaagaattg aacggaagct acaacaagtg
      301 tatggaaagc gtgattaagc agctattgag catggtgtgc gacatgaaac cagaagtcca
      361 tgtgaactac agagccacca actgaatgtg ctccacacat ccaagtccat aggcatagag
      421 tgggatacac attctgttga tattaaaggt ctgcaactgt gcacctgatg tttactataa
      481 actttcatgt cacatattta atataggtca cagaattaaa aaataagtaa catggtgtca
      541 tttctcctgg atggcgttta gtatgaagca agttaaggaa agcgagaaac ttgaatttta
      601 acacttaaac agcaaacaat cactccagta tattttcaca tttcttttta ttggcttaga
      661 aggtgcttta ttaggtattc ttcctattca atagttttta agaggagaat ataattttgt
      721 tccttagaca cctctgaaat gaatatgcaa atactttaat ttattaatta gcaagaaaac
      781 cataatattt cattggcagt tcaaaaagca tttctaaact gtctgtgaga acagagacag
      841 aaacaaatga tgttagaagt caccttagaa gaaatgggtc ccatcacagt tatccctgcc
      901 taacttcaag ttacataaat aatgttactc tgttttaagg acatttttga aagaaaaggt
      961 ggtcatctga gagagtagat atctggataa attctgtagt ttgtaaagaa gtgaacctcc
     1021 aacaaaaata attagtatgc gctaccctgc tctccttatt aaatgagcta cattctgaga
     1081 gctcgtgtac attgttagtt caatgtataa attatcttag gccttgtgtg gagaaacaga
     1141 catctagtag agctggtccc ttgcttccct gtgaggaatg tccactttaa ctcagatgtg
     1201 gagagcccac ttatggaaga tgggaaatgg aacggaagct agatagagtg atgagagctg
     1261 ccatttgaaa agttccctgc tcataatggt cattagagcc tcagaacttg acctggagtt
     1321 gcctgggaaa cagtgtcagc tctagctttc ctctggcagt gtgacatcag tgtctagacc
     1381 tttcacttac tcacaagttc cctcccagga agctttctaa atacccactg ctgagcacta
     1441 gcagtattgt tgaccttggt gggggttttg tctgtttgtg tttttgtttt gagtcaagtt
     1501 ctcactgtcc taggattcat cctatagctc aggcttcaaa ctcactggga tccgcctgct
     1561 ctgcctcctt agtgctggga ttaaaggcat gtgccactat acctcttccc agtgttagat
     1621 tttcaagcac tacatgtaga aaaattttaa ttcccaaact tcataaacat tgttatcatt
     1681 tttatagttt agaatctcag aaatagtcaa ttttatattt gaaacagatg agaaaattgg
     1741 aattccattt gattccttac tttcccaact ttatgaataa ggaaaactta ttaagttagt
     1801 ttctgggctt taggtgatct ttttcttcca ttacaagaaa aaatagttta ttccttaata
     1861 aacagaaaag cccaaaacat tccaaag
//
