LOCUS       NM_025381                635 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ATPase, H+ transporting, lysosomal V1 subunit F
            (Atp6v1f), mRNA.
ACCESSION   NM_025381
VERSION     NM_025381.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 635)
  AUTHORS   Bodzeta,A., Kahms,M. and Klingauf,J.
  TITLE     The Presynaptic v-ATPase Reversibly Disassembles and Thereby
            Modulates Exocytosis but Is Not Part of the Fusion Machinery
  JOURNAL   Cell Rep 20 (6), 1348-1359 (2017)
   PUBMED   28793259
REFERENCE   3  (bases 1 to 635)
  AUTHORS   Golder,Z.J. and Karet Frankl,F.E.
  TITLE     Extra-renal locations of the a4 subunit of H(+)ATPase
  JOURNAL   BMC Cell Biol 17 (1), 27 (2016)
   PUBMED   27368196
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 635)
  AUTHORS   Lange,C., Prenninger,S., Knuckles,P., Taylor,V., Levin,M. and
            Calegari,F.
  TITLE     The H(+) vacuolar ATPase maintains neural stem cells in the
            developing mouse cortex
  JOURNAL   Stem Cells Dev 20 (5), 843-850 (2011)
   PUBMED   21126173
  REMARK    GeneRIF: The H(+) vacuolar ATPase maintains neural stem cells in
            the developing mouse cortex.
REFERENCE   5  (bases 1 to 635)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   6  (bases 1 to 635)
  AUTHORS   Smith,A.N., Francis,R.W., Sorrell,S.L. and Karet,F.E.
  TITLE     The d subunit plays a central role in human vacuolar H(+)-ATPases
  JOURNAL   J Bioenerg Biomembr 40 (4), 371-380 (2008)
   PUBMED   18752060
REFERENCE   7  (bases 1 to 635)
  AUTHORS   Lin,Q., Donahue,S.L., Moore-Jarrett,T., Cao,S., Osipovich,A.B. and
            Ruley,H.E.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   8  (bases 1 to 635)
  AUTHORS   Wassmer,T., Froissard,M., Plattner,H., Kissmehl,R. and Cohen,J.
  TITLE     The vacuolar proton-ATPase plays a major role in several
            membrane-bounded organelles in Paramecium
  JOURNAL   J Cell Sci 118 (Pt 13), 2813-2825 (2005)
   PUBMED   15976442
  REMARK    GeneRIF: The Vacuolar F(1)F(0) ATPase was found to be crucial for
            osmoregulation, the phagocytotic pathway and the biogenesis of
            dense core secretory granules.
REFERENCE   9  (bases 1 to 635)
  AUTHORS   Sun-Wada,G.H., Yoshimizu,T., Imai-Senga,Y., Wada,Y. and Futai,M.
  TITLE     Diversity of mouse proton-translocating ATPase: presence of
            multiple isoforms of the C, d and G subunits
  JOURNAL   Gene 302 (1-2), 147-153 (2003)
   PUBMED   12527205
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK007327.1.
            
            On Apr 6, 2007 this sequence version replaced NM_025381.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007327.1, AK152929.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-635               AK007327.1         2-636
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 12.36 cM"
     gene            1..635
                     /gene="Atp6v1f"
                     /gene_synonym="1110004G16Rik"
                     /note="ATPase, H+ transporting, lysosomal V1 subunit F"
                     /db_xref="GeneID:66144"
                     /db_xref="MGI:MGI:1913394"
     exon            1..192
                     /gene="Atp6v1f"
                     /gene_synonym="1110004G16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..394
                     /gene="Atp6v1f"
                     /gene_synonym="1110004G16Rik"
                     /EC_number="7.1.2.2"
                     /note="ATPase, H+ transporting, V1 subunit F; ATPase,
                     vacuolar, 14 kD; V-ATPase subunit F; V-ATPase 14 kDa
                     subunit; vacuolar proton pump subunit F"
                     /codon_start=1
                     /product="V-type proton ATPase subunit F"
                     /protein_id="NP_079657.1"
                     /db_xref="CCDS:CCDS19960.1"
                     /db_xref="GeneID:66144"
                     /db_xref="MGI:MGI:1913394"
                     /translation="MAGRGKLIAVIGDEDTVTGFLLGGIGELNKNRHPNFLVVEKDTT
                     INEIEDTFRQFLNRDDIGIILINQYIAEMVRHALDAHQRSIPAVLEIPSKEHPYDAAK
                     DSILRRAKGMFTAEDLR"
     exon            193..635
                     /gene="Atp6v1f"
                     /gene_synonym="1110004G16Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      635
                     /gene="Atp6v1f"
                     /gene_synonym="1110004G16Rik"
                     /note="putative"
ORIGIN      
        1 aggtgtttgg gaagcgctct gcccggcgga caggatggcg ggcagaggta agctaatcgc
       61 ggtgattgga gacgaggaca cggtgactgg tttcctgttg ggcggcatag gggagctaaa
      121 caagaaccgc caccctaatt tcctggtagt ggagaaggat accaccatca atgagatcga
      181 agacactttc aggcaatttc taaacaggga tgacattggc atcattctca tcaaccagta
      241 catcgcagag atggttcggc acgccctgga tgcccaccag aggtccattc cagctgtcct
      301 ggagatcccg tccaaggagc atccctacga tgcagccaaa gactccatcc tgcgcagggc
      361 caagggcatg ttcaccgctg aagacctgcg ctagggctgc tcagccctca gccctcctca
      421 tcaccaggcc tctcctggtt tgccatgctc tatttaagtg tcaagccttg gtttccagcc
      481 cctcccttcc tcttcactga gtggctcgta agctgttggg gttcggttgt tcaggtctag
      541 gctgggtaga gaaagaaagc ccaactgttt ctccactgcc tcctccctgt gctgttaata
      601 gtatcgttgt tgatattaaa ggaattattc tctcc
//
