LOCUS       NM_133764               1849 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus ATPase, H+ transporting, lysosomal V0 subunit E2
            (Atp6v0e2), transcript variant 1, mRNA.
ACCESSION   NM_133764
VERSION     NM_133764.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1849)
  AUTHORS   Bodzeta,A., Kahms,M. and Klingauf,J.
  TITLE     The Presynaptic v-ATPase Reversibly Disassembles and Thereby
            Modulates Exocytosis but Is Not Part of the Fusion Machinery
  JOURNAL   Cell Rep 20 (6), 1348-1359 (2017)
   PUBMED   28793259
REFERENCE   2  (bases 1 to 1849)
  AUTHORS   Ueda,T., Ugawa,S. and Shimada,S.
  TITLE     A novel putative M9.2 isoform of V-ATPase expressed in the nervous
            system
  JOURNAL   Neuroreport 14 (1), 25-30 (2003)
   PUBMED   12544825
  REMARK    GeneRIF: A cDNA encoding a novel putative neuron-specific isoform
            of vacuolar proton-translocating ATPase (V-ATPase), NM9.2, was
            isolated from rat and mouse
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY296901.1, AC154013.4, AK077313.1 and AI839056.1.
            
            On Nov 22, 2008 this sequence version replaced NM_133764.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript but encodes the shorter isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC010790.1, AK077313.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                BY296901.1         1-26
            27-27               AC154013.4         26031-26031
            28-128              BY296901.1         28-128
            129-1832            AK077313.1         1-1704
            1833-1849           AI839056.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1849
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 23.52 cM"
     gene            1..1849
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /note="ATPase, H+ transporting, lysosomal V0 subunit E2"
                     /db_xref="GeneID:76252"
                     /db_xref="MGI:MGI:1923502"
     exon            1..286
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..428
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ATPase, H+ transporting, lysosomal, V0 subunit E; V-type
                     proton ATPase subunit e 2; V-ATPase subunit e 2; vacuolar
                     proton pump subunit e 2"
                     /codon_start=1
                     /product="V-type proton ATPase subunit e 2 isoform 1"
                     /protein_id="NP_598525.1"
                     /db_xref="CCDS:CCDS20103.1"
                     /db_xref="GeneID:76252"
                     /db_xref="MGI:MGI:1923502"
                     /translation="MTAHSFALPVIIFTTFWGLIGIAGPWFVPKGPNRGVIITMLVAT
                     AVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE"
     exon            287..334
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /inference="alignment:Splign:2.1.0"
     exon            335..461
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /inference="alignment:Splign:2.1.0"
     exon            462..1835
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1796..1801
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /note="hexamer: AATAAA"
     polyA_site      1815
                     /gene="Atp6v0e2"
                     /gene_synonym="0610006O14Rik; NM9.2"
                     /note="major polyA site"
ORIGIN      
        1 gtgatagcgg cgagctatcc cagcggacga tgttcaggga tgcgcgagcg cagattcgct
       61 tggtccaggg ccttcccggc tgagattccg ttgcgcatgc gcacagccct ctgccgagac
      121 ttgcacctgc ttagagtctg ccgttcgatc tgatacccca cctgagcatc gcgcacccag
      181 ccatgacagc ccattccttt gccctccctg tcatcatctt caccacattc tggggcctca
      241 tcggcatcgc tgggccctgg ttcgtgccca aaggacccaa ccgcggggtg atcatcacca
      301 tgctggtagc tactgctgtc tgctgttacc tcttctggct catcgccatc ttggcccaac
      361 tgaaccccct gtttgggcca caactgaaga atgagaccat ctggtacgtg cgtttcctgt
      421 gggagtgacc cctggggtga tcagctggct tctggcctca gatgccctgc tgtgaagggt
      481 gaatggccca gccttgatgt ccctggagac cctgcattcc ctctggcccc acccatctgt
      541 atgaccatcc tgtgctcgcc ctgccatcat gctgtggaat ccataacccc cagagccaac
      601 ctggtttcag tttctggtct cagtttcccc tgtgttccca gctattagcg gccctccatg
      661 ttgggcaagc cccgtgctca gtcaggccac agtgggagct tacctgagct taaattccca
      721 cacttggcac ttccctcttt cttccaagca gatcccggtc aaggagctgg acctgctgtt
      781 atctattttc atccagggag cagaaggcag gactcagccc agtaccagaa aggacttgag
      841 tctttgtgga gaagggacat gtggcccaaa atctctaggc tttttaactc tgtctccacc
      901 gtgttgaaat attgggtcag ggtcacaggc ctcctccagc tctgaagtga atgatatcca
      961 tttagtctct gacacttgta gatgtgacat tcctggaggt gctgatgtct taaagaagca
     1021 gtcacaccaa aaacccggca cagtcaggat caaagcctcc atgtttagcc tttagcagca
     1081 gggaaatcac ttggcatggg agggaggtag tgtgtctttg gaatgttcta gtcactttcc
     1141 tctccctctg tagataagat cgcccactcc ctagtacctg tcagttgggg tacaaccctt
     1201 tttgccactc ttcattgggt tgtggtgggg cagatcccag taccattgaa gagatttgga
     1261 gttgaggttg ggggatagac aaaggtgacg tttctggggt actactagca ctatgcctcc
     1321 ctggcttttg agaccctctg tccctaagct catatggttc tgtgccaagc acagtgagac
     1381 agaaaatgta aatgacagag gatcagccca gggcattcct ccagcccatg ccctcacctc
     1441 tctgagaggg tgagtagggc attcttgcct gtgttgccag ggcttgctag gacagaggcc
     1501 tatataatcc atggctccta accagtggct gtttgagttc ccaggggaag aaagcccagt
     1561 cttgattatc tattgactat ttatttggtc tccctcccct tatagggggg tcgttttggg
     1621 agtggcagca gaatacacta tagctcagat tgctgggcat taagtgtgct agtggctcag
     1681 atctgcagct ggggcctctg tgggcaaccc atcccgtcct accctgactc ctgaagcctt
     1741 cctgtggggg tggggcatgg tgagcatgac tcctgttgaa agccgattcc tgtctaataa
     1801 atcatggtga tgcaagattg gtttagttag ccaaaaaaaa aaaaaaaaa
//
