LOCUS       NM_001362636            4018 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ATPase, H+ transporting, lysosomal V0 subunit A1
            (Atp6v0a1), transcript variant 5, mRNA.
ACCESSION   NM_001362636 XM_006532052
VERSION     NM_001362636.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4018)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4018)
  AUTHORS   Zapata,R.C., Carretero,M., Reis,F.C.G., Chaudry,B.S., Ofrecio,J.,
            Zhang,D., Sasik,R., Ciaraldi,T., Petrascheck,M. and Osborn,O.
  TITLE     Adipocytes control food intake and weight regain via Vacuolar-type
            H+ ATPase
  JOURNAL   Nat Commun 13 (1), 5092 (2022)
   PUBMED   36042358
  REMARK    GeneRIF: Adipocytes control food intake and weight regain via
            Vacuolar-type H(+) ATPase.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4018)
  AUTHORS   Sun-Wada,G.H. and Wada,Y.
  TITLE     The a subunit isoforms of vacuolar-type proton ATPase exhibit
            differential distribution in mouse perigastrulation embryos
  JOURNAL   Sci Rep 12 (1), 13590 (2022)
   PUBMED   35948619
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4018)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4018)
  AUTHORS   Aoto,K., Kato,M., Akita,T., Nakashima,M., Mutoh,H., Akasaka,N.,
            Tohyama,J., Nomura,Y., Hoshino,K., Ago,Y., Tanaka,R., Epstein,O.,
            Ben-Haim,R., Heyman,E., Miyazaki,T., Belal,H., Takabayashi,S.,
            Ohba,C., Takata,A., Mizuguchi,T., Miyatake,S., Miyake,N.,
            Fukuda,A., Matsumoto,N. and Saitsu,H.
  TITLE     ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar
            H+-ATPases is essential for brain development in humans and mice
  JOURNAL   Nat Commun 12 (1), 2107 (2021)
   PUBMED   33833240
  REMARK    GeneRIF: ATP6V0A1 encoding the a1-subunit of the V0 domain of
            vacuolar H(+)-ATPases is essential for brain development in humans
            and mice.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4018)
  AUTHORS   Murata,Y., Sun-Wada,G.H., Yoshimizu,T., Yamamoto,A., Wada,Y. and
            Futai,M.
  TITLE     Differential localization of the vacuolar H+ pump with G subunit
            isoforms (G1 and G2) in mouse neurons
  JOURNAL   J Biol Chem 277 (39), 36296-36303 (2002)
   PUBMED   12133826
REFERENCE   7  (bases 1 to 4018)
  AUTHORS   Sobacchi,C., Frattini,A., Orchard,P., Porras,O., Tezcan,I.,
            Andolina,M., Babul-Hirji,R., Baric,I., Canham,N., Chitayat,D.,
            Dupuis-Girod,S., Ellis,I., Etzioni,A., Fasth,A., Fisher,A.,
            Gerritsen,B., Gulino,V., Horwitz,E., Klamroth,V., Lanino,E.,
            Mirolo,M., Musio,A., Matthijs,G., Nonomaya,S., Notarangelo,L.D.,
            Ochs,H.D., Superti Furga,A., Valiaho,J., van Hove,J.L., Vihinen,M.,
            Vujic,D., Vezzoni,P. and Villa,A.
  TITLE     The mutational spectrum of human malignant autosomal recessive
            osteopetrosis
  JOURNAL   Hum Mol Genet 10 (17), 1767-1773 (2001)
   PUBMED   11532986
REFERENCE   8  (bases 1 to 4018)
  AUTHORS   Toyomura,T., Oka,T., Yamaguchi,C., Wada,Y. and Futai,M.
  TITLE     Three subunit a isoforms of mouse vacuolar H(+)-ATPase.
            Preferential expression of the a3 isoform during osteoclast
            differentiation
  JOURNAL   J Biol Chem 275 (12), 8760-8765 (2000)
   PUBMED   10722719
REFERENCE   9  (bases 1 to 4018)
  AUTHORS   Nishi,T. and Forgac,M.
  TITLE     Molecular cloning and expression of three isoforms of the 100-kDa a
            subunit of the mouse vacuolar proton-translocating ATPase
  JOURNAL   J Biol Chem 275 (10), 6824-6830 (2000)
   PUBMED   10702241
REFERENCE   10 (bases 1 to 4018)
  AUTHORS   Mohlke,K.L., Purkayastha,A.A., Westrick,R.J. and Ginsburg,D.
  TITLE     Comparative mapping of distal murine chromosome 11 and human
            17q21.3 in a region containing a modifying locus for murine plasma
            von Willebrand factor level
  JOURNAL   Genomics 54 (1), 19-30 (1998)
   PUBMED   9806826
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591425.4.
            
            On Mar 2, 2023 this sequence version replaced NM_001362636.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784647.94707.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                AL591425.4         15604-15651
            49-229              AL591425.4         17844-18024
            230-308             AL591425.4         24651-24729
            309-406             AL591425.4         26560-26657
            407-535             AL591425.4         27141-27269
            536-618             AL591425.4         32768-32850
            619-745             AL591425.4         33354-33480
            746-828             AL591425.4         35263-35345
            829-922             AL591425.4         36497-36590
            923-1135            AL591425.4         39988-40200
            1136-1286           AL591425.4         42809-42959
            1287-1426           AL591425.4         44246-44385
            1427-1584           AL591425.4         44777-44934
            1585-1675           AL591425.4         45908-45998
            1676-1794           AL591425.4         49037-49155
            1795-2011           AL591425.4         49878-50094
            2012-2119           AL591425.4         50603-50710
            2120-2194           AL591425.4         51523-51597
            2195-2302           AL591425.4         54505-54612
            2303-2320           AL591425.4         55546-55563
            2321-2438           AL591425.4         61113-61230
            2439-2610           AL591425.4         61521-61692
            2611-4018           AL591425.4         68399-69806
FEATURES             Location/Qualifiers
     source          1..4018
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 64.04 cM"
     gene            1..4018
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /note="ATPase, H+ transporting, lysosomal V0 subunit A1"
                     /db_xref="GeneID:11975"
                     /db_xref="MGI:MGI:103286"
     exon            1..48
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            49..229
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..2704
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /EC_number="7.1.2.2"
                     /note="isoform 5 is encoded by transcript variant 5;
                     ATPase, H+ transporting, lysosomal V0 subunit a; ATPase,
                     H+ transporting, lysosomal (vacuolar proton pump)
                     noncatalytic accessory protein 1 (110/160 kDa); ATPase, H+
                     transporting, lysosomal (vacuolar proton pump)
                     noncatalytic accessory protein 1A (110/160 kDa); V-type
                     proton ATPase 116 kDa subunit a; vacuolar proton pump
                     subunit 1; vacuolar adenosine triphosphatase subunit
                     Ac116; vacuolar proton translocating ATPase 116 kDa
                     subunit a; clathrin-coated vesicle/synaptic vesicle proton
                     pump 116 kDa subunit; V-ATPase a1; V-ATPase 116 kDa
                     subunit a1; V-type proton ATPase 116 kDa subunit a1;
                     V-ATPase 116 kDa subunit a 1; V-type proton ATPase 116 kDa
                     subunit a 1"
                     /codon_start=1
                     /product="V-type proton ATPase 116 kDa subunit a 1 isoform
                     5"
                     /protein_id="NP_001349565.1"
                     /db_xref="GeneID:11975"
                     /db_xref="MGI:MGI:103286"
                     /translation="MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDV
                     NVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFE
                     KIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPNEM
                     GRGAPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKS
                     VFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTE
                     DHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQ
                     FALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTHGFQNIVDAYGIGTYREINPA
                     PYTVITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKHENEMFSMVFSGRYII
                     LLMGLFSIYTGLIYNDCFSKSLNIFGSSWSVRPMFTQGNWTEETLLGSSVLQLNPAIP
                     GVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKP
                     LNIYFGFIPEIIFMSSLFGYLVILIFYKWTAYDAHSSRNAPSLLIHFINMFLFSYPES
                     GNAMLYSGQKGIQCFLIVVAMLCVPWMLLFKPLILRHQYLRKKHLEGQPVEAPVTPTP
                     SQQGLEAAPAATGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDAEEPTEDEVFDFG
                     DTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLHVRSLAGG
                     LGLFFIFAAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYTGTGFKFLPFSFEHI
                     REGKFDE"
     exon            230..308
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            309..406
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            407..535
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            536..618
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            619..745
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            746..828
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            829..922
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1135
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1286
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1426
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1584
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1675
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1794
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..2011
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2119
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2120..2194
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2195..2302
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2303..2320
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2321..2438
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2439..2610
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     exon            2611..4018
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3992..3997
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /note="hexamer: AATAAA"
     polyA_site      4018
                     /gene="Atp6v0a1"
                     /gene_synonym="ATP6a1; Atp6n1; Atp6n1a; Atpv0a1; Vpp-1;
                     Vpp1"
                     /note="major polyA site"
ORIGIN      
        1 gctttgctgc ggcggctgcg gtcgcggcgg cggcggagcc ggcgagaggt taattctcaa
       61 gccaagtcat tttctctctt gcctcggatt ggagtgaact accatcgcca ccatggggga
      121 gcttttccgg agtgaggaga tgacgctggc ccagctattt ctacagtctg aagctgctta
      181 ttgctgtgtc agtgaattag gagagcttgg gaaggtccaa tttcgggatt taaatccaga
      241 tgtgaatgtt ttccagagga aatttgtgaa tgaagttaga agatgtgaag aaatggatcg
      301 aaaactccga tttgttgaga aagagataag gaaagctaac atcccaatta tggacaccgg
      361 tgaaaaccca gaggtgccct tccctcggga catgatcgac ttagaggcca atttcgagaa
      421 gattgaaaat gaactgaagg aaatcaacac taaccaggaa gctctgaaga gaaacttcct
      481 ggaactgact gaattaaaat ttatcctgcg aaaaacccag cagtttttcg atgagatggc
      541 ggatccagac ctgttggaag agtcctcatc actcttggag ccaaacgaga tgggaagagg
      601 cgcaccctta cgacttggct ttgtggctgg tgtgattaac cgggagcgga tcccgacctt
      661 tgagcgcatg ctttggcgag tgtgccgagg gaatgtgttc ctgagacaag ctgaaatcga
      721 aaacccgctg gaggatcctg tgactggcga ctacgtgcac aagtctgtgt tcatcatttt
      781 tttccaaggc gatcagctga aaaacagggt caagaaaatc tgtgaagggt tccgagcctc
      841 cctctatccc tgccctgaga ctccacagga aaggaaagaa atggcttccg gagtcaatac
      901 caggatcgac gacctccaaa tggttctgaa tcagacggag gaccaccgcc agagggttct
      961 gcaggcagct gctaagaaca tccgcgtctg gttcatcaag gtgcggaaga tgaaggctat
     1021 ctaccatacc ctgaacctgt gcaatataga cgtgacccag aagtgcctga tcgcagaagt
     1081 ctggtgccct gtcactgacc tggactccat ccagtttgca ctacgaagag gcacggaaca
     1141 cagtgggtcc actgtcccct ccattctgaa caggatgcag acaaaccaga caccgccgac
     1201 atataataaa accaacaagt tcacgcacgg cttccagaac atagtagatg cttatgggat
     1261 cggcacttac cgagagatta acccagctcc gtacactgtc atcaccttcc cctttctgtt
     1321 tgctgtgatg ttcggagatt ttgggcacgg cattttgatg acgctgtttg ctgtgtggat
     1381 ggtgttgagg gagagccgga tcctctccca gaagcacgag aatgagatgt ttagcatggt
     1441 gttcagcggc cggtacatta ttcttctgat gggactgttc tccatctata ctggactcat
     1501 ctacaatgac tgcttttcca agtctctgaa tatctttggg tcatcgtgga gtgtacggcc
     1561 aatgttcact caagggaact ggacggagga gacgcttctg gggagttctg ttctccagtt
     1621 gaaccccgct atccctggag tttttggtgg cccgtacccg tttggcattg atccgatttg
     1681 gaacattgca accaacaagc tgaccttcct caactccttc aagatgaaga tgtctgttat
     1741 cctcggcatc atccacatgc tgtttggagt cagcctgagc cttttcaacc atatctattt
     1801 caagaagccc ctgaacatct actttggctt tattcctgag atcatcttca tgtcctcgtt
     1861 gtttggctac ctggtcatcc ttatctttta caagtggaca gcctacgatg cccactcgtc
     1921 taggaatgcc ccgagcctcc tgatccactt cataaacatg ttcctcttct cctacccaga
     1981 gtctggtaat gcaatgctgt actctggaca gaaaggaatt cagtgtttcc tcatcgtggt
     2041 ggcgatgctc tgcgtccctt ggatgcttct gtttaagccg ctgatccttc gccatcagta
     2101 cctgaggaag aagcatttgg aagggcaacc cgtggaggcc ccagtcacac caaccccgag
     2161 ccaacaggga ctagaggcag caccggctgc aacaggaact ctcaactttg gtgggatcag
     2221 ggtgggcaac ggaccgacag aggaggatgc tgaaattatt cagcatgacc agctttccac
     2281 ccattcagag gacgcagaag agcctaccga ggacgaagtg tttgactttg gcgacaccat
     2341 ggtccaccag gccatccaca ccattgagta ctgcttgggt tgtatctcca acaccgcgtc
     2401 gtacctgcga ctctgggccc tcagcctggc ccacgcacag ctctctgaag tactttggac
     2461 catggtgatc cacattggcc tgcacgtccg gagtttggcc gggggtctag ggctgttttt
     2521 catcttcgcc gcctttgcca cgctgaccgt ggctatcctg ctgatcatgg agggcctctc
     2581 ggccttcctc cacgcgctgc ggttacactg ggtggagttc cagaacaaat tctacactgg
     2641 gactggcttc aagttcctcc ccttctcctt tgagcacatt cgggaaggga agtttgatga
     2701 gtgagtctga ggcagggcgc atgcccagag cagctcccct gcccgtctcc acagtgatca
     2761 gctgtgtctc tcttgcctgc tggttgtgat ccctggatgc ctgggccttt gtgtcgccct
     2821 gcaacccctt gtccctgctg tgactcactt aggtagtgct ggccttgcct cggtctctct
     2881 accccaaaac tttggattga atgctgaatg actgtgcctg atactcaccc atccccacgg
     2941 caccggctag gccccttggc cccccagaca gacagccctg ttccaccccc tgctggtgag
     3001 ccaacctgca cagccacatc ggggcacaga gccctcagga tgcaagggat ccctcttcag
     3061 tccaggagtt cttggtcaca ccttggagga ggatggtaat tggtcctctc ctacaggggg
     3121 acactgctta tgaaacacat cccactccac tagcagggac agtcaggaag atgctgcggt
     3181 catcccttgc ccagccctct ccagttaata ttcaggaaat taggctggcc ccacctggac
     3241 catcccaaag gtcccaggat agccaccacc ctcctaagca ccccctcctc gagccctgtt
     3301 ggcgcagcat agcatccctg ggactggggg ggtctcaccg acttgcagca ctgggcttcc
     3361 ggatcttagg ttccctccac ccagtctgta ggtgaatggg ccttgcccaa cactacaccc
     3421 caaggcagaa gttaaaattg gcccatctct gagcccttct gcaccctgat catgatgtcc
     3481 tgaggctgtg gtcagtaagg ttggttctgc tggcaggcct gccttgatct gcccactgag
     3541 actccctccc caagccccgc actgacccca ggtttcagga gtggtgtcct gggcagggaa
     3601 ggtcatttac aatttgctaa gcggaggtga ctgttgggct gccagcgcag gtatgggagc
     3661 gctgcccagg cctgccaagc cctcgccggc tacctcatgt actgtggatc tcagaccctt
     3721 ctaatcatgt gctgactcct gcaattcact cactgccttc cctgtggaag tgacactaaa
     3781 tcagcaaggc ccctcccctc ccccacccag gtgctcatga gaactacccc cacactcgcc
     3841 caggcaggac cggcccatgg tgaccttgtt ctgaacccct ctgtcctttt gtgcccggtt
     3901 acgtgatctt tgctctgttt gcagagaggc ctgcagcaga gctctttgtg gggaccctgt
     3961 ccaaggcctt ctgtccagac atcttatccg gaataaagtg tgtttgactc tcagaaaa
//
