LOCUS       NM_009725               1135 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ATP synthase peripheral stalk-membrane subunit b
            (Atp5pb), transcript variant 1, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_009725 XM_030252395
VERSION     NM_009725.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1135)
  AUTHORS   Ruan,Q.T., Yazdani,N., Blum,B.C., Beierle,J.A., Lin,W.,
            Coelho,M.A., Fultz,E.K., Healy,A.F., Shahin,J.R., Kandola,A.K.,
            Luttik,K.P., Zheng,K., Smith,N.J., Cheung,J., Mortazavi,F.,
            Apicco,D.J., Ragu Varman,D., Ramamoorthy,S., Ash,P.E.A.,
            Rosene,D.L., Emili,A., Wolozin,B., Szumlinski,K.K. and Bryant,C.D.
  TITLE     A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced
            Reinforcement, Reward, and Dopamine Release and Increases
            Synaptosomal hnRNP H and Mitochondrial Proteins
  JOURNAL   J Neurosci 40 (1), 107-130 (2020)
   PUBMED   31704785
REFERENCE   3  (bases 1 to 1135)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1135)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   5  (bases 1 to 1135)
  AUTHORS   Lehman,J.J., Barger,P.M., Kovacs,A., Saffitz,J.E., Medeiros,D.M.
            and Kelly,D.P.
  TITLE     Peroxisome proliferator-activated receptor gamma coactivator-1
            promotes cardiac mitochondrial biogenesis
  JOURNAL   J Clin Invest 106 (7), 847-856 (2000)
   PUBMED   11018072
REFERENCE   6  (bases 1 to 1135)
  AUTHORS   Babalola,G.O. and Schultz,R.M.
  TITLE     Modulation of gene expression in the preimplantation mouse embryo
            by TGF-alpha and TGF-beta
  JOURNAL   Mol Reprod Dev 41 (2), 133-139 (1995)
   PUBMED   7654366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC025786.16.
            
            On or before Apr 6, 2020 this sequence version replaced
            XM_030252395.1, NM_009725.4.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK019459.1, AK168041.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               AC025786.16        107713-107828
            117-153             AC025786.16        108078-108114
            154-299             AC025786.16        110935-111080
            300-463             AC025786.16        112795-112958
            464-589             AC025786.16        115260-115385
            590-769             AC025786.16        123110-123289
            770-1135            AC025786.16        123913-124278
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 46.46 cM"
     gene            1..1135
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /note="ATP synthase peripheral stalk-membrane subunit b"
                     /db_xref="GeneID:11950"
                     /db_xref="MGI:MGI:1100495"
     exon            1..116
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..847
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /note="isoform 1 is encoded by transcript variant 1; ATP
                     synthase subunit b, mitochondrial; ATPase subunit b; ATP
                     synthase, H+ transporting, mitochondrial F0 complex,
                     subunit B1; ATP synthase F(0) complex subunit B1,
                     mitochondrial"
                     /codon_start=1
                     /product="ATP synthase F(0) complex subunit B1,
                     mitochondrial isoform 1"
                     /protein_id="NP_033855.2"
                     /db_xref="CCDS:CCDS17714.1"
                     /db_xref="GeneID:11950"
                     /db_xref="MGI:MGI:1100495"
                     /translation="MLSRVVLSAAATAAPCLKNAAALGPGVLQATRAFHTGQPRLAPL
                     PPLPEYGGKVRLGLIPEEFFQFLYPKTGVTGPYVLGTGLSLYFLSKEIYVITPETFST
                     ISVVGLIVYVIKKYGASFGEFIDKLNEEKIAQLEEVKQSSMKQIQDAIDMEKAQQALV
                     QKRHYLFDVQRNNIALALEVTYRERLHKAYKEVKNRLDYHISVQNMMRRKEEEHMIDW
                     VEKHVVKSISVQQEKETIAKCIEDLKLLAKKAQAQPIM"
     exon            117..153
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /inference="alignment:Splign:2.1.0"
     exon            154..299
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /inference="alignment:Splign:2.1.0"
     exon            300..463
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /inference="alignment:Splign:2.1.0"
     exon            464..589
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /inference="alignment:Splign:2.1.0"
     exon            590..769
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /inference="alignment:Splign:2.1.0"
     exon            770..1135
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1115..1120
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /note="hexamer: AATAAA"
     polyA_site      1135
                     /gene="Atp5pb"
                     /gene_synonym="Atp5f1"
                     /note="major polyA site"
ORIGIN      
        1 atcttgctcc tgcccctgac aggctcgggt cggggtcaca gggacacgga gcccgctgtc
       61 ccgctcttcg cagacaatgc tgtcccgggt ggtgctttct gctgccgcca cagcggcccc
      121 gtgtctgaag aacgcggccg ccctaggtcc aggggtatta caggcaacaa gggcctttca
      181 cacaggacag cctcgccttg cccctctacc acctcttcct gaatatggag gaaaagtgcg
      241 tcttgggctg attcctgagg aatttttcca gttcctttac cctaagactg gtgtaacagg
      301 accttatgtg cttggaactg gacttagctt gtattttcta tccaaagaaa tatatgtgat
      361 taccccagag accttctcta ccatatcagt agtagggttg atagtctatg tgattaagaa
      421 atatggcgcc tcttttggag aatttattga caaacttaat gaggaaaaaa ttgctcaact
      481 agaagaagta aagcagtcga gcatgaaaca aatccaggat gcaatcgaca tggagaaggc
      541 acagcaggca ctggttcaga agcgccatta cctcttcgat gtgcagagga ataacattgc
      601 cctggccttg gaggtcactt accgggaacg gctacataaa gcatataagg aggtaaagaa
      661 tcgcctggac taccacatct ctgtacagaa catgatgcgt cgcaaggagg aagaacacat
      721 gatagactgg gtagaaaagc atgtggtgaa gagcatttct gtacagcagg aaaaggagac
      781 cattgccaag tgcattgaag atctaaagct gcttgcaaag aaggctcaag ctcagccaat
      841 tatgtgaata tgtctttctc agttgtgata gccagagaga gttaaatggg aactagtata
      901 tgtgaagaac tctttctgta ttgctatcta ttgaaataaa atgatcaagg tccacttagt
      961 ggcttaaccc tattggccag taaggtattt ctgatccttg ctctgtatgc ggagttatct
     1021 gatcataatt tgaataagca acttgcagca acttgctgcc caactgaaat taccaagtta
     1081 taatttaaac ttgtaattaa ctaaagcatc ttgcaataaa atgtttgaaa cagaa
//
