LOCUS       NM_025313                931 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus ATP synthase F1 subunit delta (Atp5f1d), transcript
            variant 1, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_025313
VERSION     NM_025313.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 931)
  AUTHORS   Wang,Y.B., Zhai,C.Y., Yao,G.P., Chen,T.B., Xue,L.L., Zhou,L.,
            Xiong,L.L. and Wang,T.H.
  TITLE     ATP5D Is a Potential Biomarker for Male Fertility
  JOURNAL   Oxid Med Cell Longev 2023, 4923614 (2023)
   PUBMED   36686378
  REMARK    GeneRIF: ATP5D Is a Potential Biomarker for Male Fertility.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 931)
  AUTHORS   Pecina,P., Nuskova,H., Karbanova,V., Kaplanova,V., Mracek,T. and
            Houstek,J.
  TITLE     Role of the mitochondrial ATP synthase central stalk subunits gamma
            and delta in the activity and assembly of the mammalian enzyme
  JOURNAL   Biochim Biophys Acta Bioenerg 1859 (5), 374-381 (2018)
   PUBMED   29499186
  REMARK    GeneRIF: Both gamma and delta subunits silenced cells displayed
            decreased ATP synthase function - lowered rate of ADP-stimulated
            respiration, a two-fold increased sensitivity of respiration to
            inhibitor oligomycin, and impaired utilization of mitochondrial
            membrane potential for ADP phosphorylation.
REFERENCE   3  (bases 1 to 931)
  AUTHORS   Poche,R.A., Zhang,M., Rueda,E.M., Tong,X., McElwee,M.L., Wong,L.,
            Hsu,C.W., Dejosez,M., Burns,A.R., Fox,D.A., Martin,J.F., Zwaka,T.P.
            and Dickinson,M.E.
  TITLE     RONIN Is an Essential Transcriptional Regulator of Genes Required
            for Mitochondrial Function in the Developing Retina
  JOURNAL   Cell Rep 14 (7), 1684-1697 (2016)
   PUBMED   26876175
REFERENCE   4  (bases 1 to 931)
  AUTHORS   Liu,H., Zhao,Z., Zhong,Y., Shan,Y., Sun,X., Mao,B. and Cong,Y.
  TITLE     Identification of a new Mpl-interacting protein, Atp5d
  JOURNAL   Mol Cell Biochem 391 (1-2), 85-94 (2014)
   PUBMED   24615392
  REMARK    GeneRIF: The interaction between Mpl and Atp5d was confirmed by the
            yeast two-hybrid system, mammalian two-hybrid assay, pull-down
            experiment, and co-immunoprecipitation study in vivo and in vitro.
REFERENCE   5  (bases 1 to 931)
  AUTHORS   Chaignat,E., Yahya-Graison,E.A., Henrichsen,C.N., Chrast,J.,
            Schutz,F., Pradervand,S. and Reymond,A.
  TITLE     Copy number variation modifies expression time courses
  JOURNAL   Genome Res 21 (1), 106-113 (2011)
   PUBMED   21084671
REFERENCE   6  (bases 1 to 931)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AA409366.1, AK151151.1 and BY451544.1.
            
            [WARNING] On Apr 23, 2024 this sequence was replaced by
            NM_025313.3.
            
            On Feb 5, 2008 this sequence version replaced NM_025313.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU560013.1, AK155285.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: reported by MitoCarta
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                AA409366.1         6-71
            67-924              AK151151.1         2-859
            925-931             BY451544.1         460-466
FEATURES             Location/Qualifiers
     source          1..931
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..931
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /note="ATP synthase F1 subunit delta"
                     /db_xref="GeneID:66043"
                     /db_xref="MGI:MGI:1913293"
     exon            1..292
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..658
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /EC_number="3.6.1.14"
                     /EC_number="7.1.2.2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; ATP synthase subunit delta, mitochondrial;
                     F-ATPase delta subunit; ATP synthase, H+ transporting,
                     mitochondrial F1 complex, delta subunit"
                     /codon_start=1
                     /product="ATP synthase subunit delta, mitochondrial
                     isoform 1 precursor"
                     /protein_id="NP_079589.2"
                     /db_xref="CCDS:CCDS24010.1"
                     /db_xref="GeneID:66043"
                     /db_xref="MGI:MGI:1913293"
                     /translation="MLPASLLRHPGLRRLMLQARTYAEAAAAPAPAAGPGQMSFTFAS
                     PTQVFFDSANVKQVDVPTLTGAFGILASHVPTLQVLRPGLVVVHTEDGTTTKYFVSSG
                     SVTVNADSSVQLLAEEAVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEAN
                     EALVKALE"
     exon            293..446
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /inference="alignment:Splign:2.1.0"
     exon            447..535
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /inference="alignment:Splign:2.1.0"
     exon            536..931
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /inference="alignment:Splign:2.1.0"
     regulatory      908..913
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /note="putative"
     polyA_site      924
                     /gene="Atp5f1d"
                     /gene_synonym="0610008F14Rik; 1500000I11Rik; Atp5d"
                     /note="putative"
ORIGIN      
        1 ccttcggaga atcctgtgcg cgtgcgttct tgtgggaact gcgcctccca gaaggcaccg
       61 cgcgtcgtcc ttctccctcc ctgaaggccg cctcgcttgc ccagtgtgtc ggccgcccgc
      121 gaagctagag tccactgact tttccgccac catgttgccc gcctcactgc ttcgtcaccc
      181 gggcctgcgc cgcctgatgc ttcaggcgcg tacatacgcc gaggccgccg ctgcacctgc
      241 ccccgccgcc gggcccggac agatgtcctt cacctttgcc tccccgacgc aggtgttctt
      301 tgacagtgcc aacgtcaagc aagtggacgt gcctacgctg actggagcct ttggcatctt
      361 ggcatcccat gtccccacac tacaggtcct acggcctggg ctggtagtgg ttcacacaga
      421 agacggcacc acgactaagt actttgtgag cagcggctcc gtcactgtga atgccgactc
      481 ctctgtgcag ttactagctg aagaagctgt gacactggac atgctggacc tgggggcagc
      541 ccgggccaac ctggagaagg cgcagtcaga actgtcaggt gcggcggacg aggcagcacg
      601 ggctgagatc cagatccgta ttgaggccaa tgaagcccta gtgaaggccc tggagtaggt
      661 ggtacctact gtctgacacc cacggggaaa ctgagccagg tccaggccga tgagaagttc
      721 ccagtgggct gaagtggcca ccaggggtca gcagtgctcc agttgctggg cttaaagctt
      781 cctggtgcct gtctgccagg tcatggagga ttccccaatc tggcatcccc acgatgcctc
      841 tggagagatg gccttgattg cccctcaaag ccacctgaac cgtcgtcaac ttacccagcc
      901 tgtctccatt aaacaccagg aaccaactga g
//
