LOCUS       NM_009724               1327 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus ATPase, H+/K+ exchanging, beta polypeptide (Atp4b),
            mRNA.
ACCESSION   NM_009724
VERSION     NM_009724.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1327)
  AUTHORS   Shi,W. and Filmus,J.
  TITLE     Glypican-6 and Glypican-4 stimulate embryonic stomach growth by
            regulating Hedgehog and noncanonical Wnt signaling
  JOURNAL   Dev Dyn 251 (12), 2015-2028 (2022)
   PUBMED   36057966
REFERENCE   2  (bases 1 to 1327)
  AUTHORS   Tran,C.P., Scurr,M., O'Connor,L., Buzzelli,J.N., Ng,G.Z.,
            Chin,S.C.N., Stamp,L.A., Minamoto,T., Giraud,A.S., Judd,L.M.,
            Sutton,P. and Menheniott,T.R.
  TITLE     IL-33 promotes gastric tumour growth in concert with activation and
            recruitment of inflammatory myeloid cells
  JOURNAL   Oncotarget 13, 785-799 (2022)
   PUBMED   35677533
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1327)
  AUTHORS   Rodriguez-Seguel,E., Villamayor,L., Arroyo,N., De Andres,M.P.,
            Real,F.X., Martin,F., Cano,D.A. and Rojas,A.
  TITLE     Loss of GATA4 causes ectopic pancreas in the stomach
  JOURNAL   J Pathol 250 (4), 362-373 (2020)
   PUBMED   31875961
REFERENCE   4  (bases 1 to 1327)
  AUTHORS   Francis,R., Guo,H., Streutker,C., Ahmed,M., Yung,T., Dirks,P.B.,
            He,H.H. and Kim,T.H.
  TITLE     Gastrointestinal transcription factors drive lineage-specific
            developmental programs in organ specification and cancer
  JOURNAL   Sci Adv 5 (12), eaax8898 (2019)
   PUBMED   31844668
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1327)
  AUTHORS   Chen,L., Toke,N.H., Luo,S., Vasoya,R.P., Aita,R., Parthasarathy,A.,
            Tsai,Y.H., Spence,J.R. and Verzi,M.P.
  TITLE     HNF4 factors control chromatin accessibility and are redundantly
            required for maturation of the fetal intestine
  JOURNAL   Development 146 (19) (2019)
   PUBMED   31345929
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1327)
  AUTHORS   Mathews,P.M., Claeys,D., Jaisser,F., Geering,K., Horisberger,J.D.,
            Kraehenbuhl,J.P. and Rossier,B.C.
  TITLE     Primary structure and functional expression of the mouse and frog
            alpha-subunit of the gastric H(+)-K(+)-ATPase
  JOURNAL   Am J Physiol 268 (5 Pt 1), C1207-C1214 (1995)
   PUBMED   7762614
  REMARK    Erratum:[Am J Physiol 1995 Oct;269(4 Pt 1):section C followi]
REFERENCE   7  (bases 1 to 1327)
  AUTHORS   Deng,A.Y., Gu,L., Rapp,J.P., Szpirer,C. and Szpirer,J.
  TITLE     Chromosomal assignment of 11 loci in the rat by mouse-rat somatic
            hybrids and linkage
  JOURNAL   Mamm Genome 5 (11), 712-716 (1994)
   PUBMED   7873882
REFERENCE   8  (bases 1 to 1327)
  AUTHORS   Morley,G.P., Callaghan,J.M., Rose,J.B., Toh,B.H., Gleeson,P.A. and
            van Driel,I.R.
  TITLE     The mouse gastric H,K-ATPase beta subunit. Gene structure and
            co-ordinate expression with the alpha subunit during ontogeny
  JOURNAL   J Biol Chem 267 (2), 1165-1174 (1992)
   PUBMED   1370459
REFERENCE   9  (bases 1 to 1327)
  AUTHORS   Canfield,V.A. and Levenson,R.
  TITLE     Structural organization and transcription of the mouse gastric H+,
            K(+)-ATPase beta subunit gene
  JOURNAL   Proc Natl Acad Sci U S A 88 (18), 8247-8251 (1991)
   PUBMED   1654563
REFERENCE   10 (bases 1 to 1327)
  AUTHORS   Canfield,V.A., Okamoto,C.T., Chow,D., Dorfman,J., Gros,P.,
            Forte,J.G. and Levenson,R.
  TITLE     Cloning of the H,K-ATPase beta subunit. Tissue-specific expression,
            chromosomal assignment, and relationship to Na,K-ATPase beta
            subunits
  JOURNAL   J Biol Chem 265 (32), 19878-19884 (1990)
   PUBMED   1978834
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC130818.3.
            
            On Mar 21, 2007 this sequence version replaced NM_009724.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009499.1, AK008180.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               AC130818.3         64708-64844
            138-266             AC130818.3         67922-68050
            267-380             AC130818.3         71383-71496
            381-580             AC130818.3         71621-71820
            581-637             AC130818.3         72667-72723
            638-748             AC130818.3         73947-74057
            749-1327            AC130818.3         74699-75277
FEATURES             Location/Qualifiers
     source          1..1327
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 5.89 cM"
     gene            1..1327
                     /gene="Atp4b"
                     /note="ATPase, H+/K+ exchanging, beta polypeptide"
                     /db_xref="GeneID:11945"
                     /db_xref="MGI:MGI:88114"
     exon            1..137
                     /gene="Atp4b"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..910
                     /gene="Atp4b"
                     /note="proton pump beta chain; gastric H(+)/K(+) ATPase
                     subunit beta; H+,K+-ATPase; ATPase, H+/K+ transporting,
                     beta polypeptide, gastric specific; H+/K+-ATPase beta;
                     H,K-ATPase-Beta"
                     /codon_start=1
                     /product="potassium-transporting ATPase subunit beta"
                     /protein_id="NP_033854.1"
                     /db_xref="CCDS:CCDS22111.1"
                     /db_xref="GeneID:11945"
                     /db_xref="MGI:MGI:88114"
                     /translation="MAALQEKKSCSQRMAEFRHYCWNPDTGQMLGRTPARWVWISLYY
                     AGFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPGVTLRPDVYGERGLKISYNVSE
                     NSSWAGLTHTLHSFLAGYTPASQQDSINCTSEKYFFQESFAAPNHTKFSCKFTADMLQ
                     NCSGLADPSFGFEEGKPCFIIKMNRIVKFLPSNNTAPRVDCTFQDDPQKPRKDTEPLQ
                     VEYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNVPKNMQVSIVCKILADHVTFN
                     NPHDPYEGKVEFKLTIQK"
     exon            138..266
                     /gene="Atp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            267..380
                     /gene="Atp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            381..580
                     /gene="Atp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            581..637
                     /gene="Atp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            638..748
                     /gene="Atp4b"
                     /inference="alignment:Splign:2.1.0"
     exon            749..1327
                     /gene="Atp4b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagtccagg caagcaggag aggacatggc agccctgcag gagaagaagt catgcagcca
       61 gcgcatggcc gaattccggc actactgttg gaacccggac actgggcaaa tgctgggccg
      121 caccccagcc cggtgggtgt ggatcagcct gtactacgca ggtttctatg tggtcatgac
      181 cgggctcttt gccttgtgca tctatgtgct gatgcagacc attgacccct acaccccaga
      241 ctaccaggac cagttaaagt caccaggggt aaccttgaga ccggacgtgt atggggaaag
      301 agggctgaag atttcctaca atgtctctga aaacagttcc tgggctggcc tcacacacac
      361 cctgcacagc ttcttagcag gctatacccc agcatcccag caggacagca tcaactgtac
      421 atctgaaaag tacttcttcc aggagagctt tgcagctcca aaccacacca agttctcctg
      481 caagttcact gcagacatgc tacaaaactg ctcaggcctg gcggacccca gcttcggctt
      541 cgaggagggg aagccctgct tcattattaa aatgaacaga attgtcaagt tcctccccag
      601 caacaacaca gctccccgag tggactgcac cttccaggat gatccccaaa agccccggaa
      661 ggacactgaa cccctgcagg tcgagtacta tccccccaat ggcaccttca gtctccacta
      721 tttcccctac tatggcaaga aagcacagcc ccactacagc aaccctctgg tggcagccaa
      781 gctcctcaac gtccccaaga acatgcaagt cagcatcgtg tgcaagatcc tggcagacca
      841 cgtgaccttc aacaaccccc atgaccccta cgaagggaag gtggagttta aacttacaat
      901 acagaagtaa aacgtgggag tggtgtccac ccctcagatg ggtggacacg gatggacact
      961 cttcctgact gcacagcctc tgctggccag catgcacggc cacttccatc atggcccaga
     1021 gctgacacca ggaagtgctc cagcccagca ctccccgagt atcaccaacc ctcacgtgag
     1081 cgcaatccta tcggagctgt ggggttaaca cggggaccca gagtccggct gccactaagg
     1141 aaggcctatc tgtccacatt tctgtcctgt gatcatttgc ccgtcctgca cttcaatatg
     1201 aactatgggt ccacatcagg gtaacactgg tcaccctggc atgacacatc tccagttcgt
     1261 gcttctgaga ccacagtccc tatgccatca aaacaaacta tattaaagtt attcttattc
     1321 tgtgtga
//
