LOCUS       NM_001128096            7310 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus ATPase type 13A3 (Atp13a3), transcript variant 1,
            mRNA.
ACCESSION   NM_001128096
VERSION     NM_001128096.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7310)
  AUTHORS   Liu,B., Azfar,M., Legchenko,E., West,J.A., Martin,S., Van den
            Haute,C., Baekelandt,V., Wharton,J., Howard,L., Wilkins,M.R.,
            Vangheluwe,P., Morrell,N.W. and Upton,P.D.
  TITLE     ATP13A3 variants promote pulmonary arterial hypertension by
            disrupting polyamine transport
  JOURNAL   Cardiovasc Res 120 (7), 756-768 (2024)
   PUBMED   38626311
  REMARK    GeneRIF: ATP13A3 variants promote pulmonary arterial hypertension
            by disrupting polyamine transport.
REFERENCE   2  (bases 1 to 7310)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7310)
  AUTHORS   Schultheis,P.J., Hagen,T.T., O'Toole,K.K., Tachibana,A.,
            Burke,C.R., McGill,D.L., Okunade,G.W. and Shull,G.E.
  TITLE     Characterization of the P5 subfamily of P-type transport ATPases in
            mice
  JOURNAL   Biochem Biophys Res Commun 323 (3), 731-738 (2004)
   PUBMED   15381061
REFERENCE   4  (bases 1 to 7310)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154608.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164139
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               AC154608.3         114668-114850       c
            184-229             AC154608.3         113927-113972       c
            230-330             AC154608.3         93155-93255         c
            331-504             AC154608.3         88896-89069         c
            505-675             AC154608.3         88134-88304         c
            676-746             AC154608.3         87740-87810         c
            747-827             AC154608.3         85989-86069         c
            828-897             AC154608.3         83525-83594         c
            898-1032            AC154608.3         82073-82207         c
            1033-1105           AC154608.3         80552-80624         c
            1106-1237           AC154608.3         78588-78719         c
            1238-1417           AC154608.3         77549-77728         c
            1418-1575           AC154608.3         77283-77440         c
            1576-1764           AC154608.3         76005-76193         c
            1765-1826           AC154608.3         74370-74431         c
            1827-1977           AC154608.3         73946-74096         c
            1978-2094           AC154608.3         70842-70958         c
            2095-2112           AC154608.3         70210-70227         c
            2113-2266           AC154608.3         69963-70116         c
            2267-2387           AC154608.3         69754-69874         c
            2388-2512           AC154608.3         67473-67597         c
            2513-2688           AC154608.3         66543-66718         c
            2689-2811           AC154608.3         66096-66218         c
            2812-2891           AC154608.3         65933-66012         c
            2892-2934           AC154608.3         64947-64989         c
            2935-3044           AC154608.3         64752-64861         c
            3045-3141           AC154608.3         63822-63918         c
            3142-3214           AC154608.3         62510-62582         c
            3215-3383           AC154608.3         60079-60247         c
            3384-3571           AC154608.3         58519-58706         c
            3572-3660           AC154608.3         55276-55364         c
            3661-3741           AC154608.3         49192-49272         c
            3742-3831           AC154608.3         48126-48215         c
            3832-7310           AC154608.3         38743-42221         c
FEATURES             Location/Qualifiers
     source          1..7310
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 21.26 cM"
     gene            1..7310
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /note="ATPase type 13A3"
                     /db_xref="GeneID:224088"
                     /db_xref="MGI:MGI:2685387"
     exon            1..183
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            184..229
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            230..330
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     CDS             280..4029
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /EC_number="7.6.2.16"
                     /note="isoform 1 is encoded by transcript variant 1;
                     probable cation-transporting ATPase 13A3; type V P-type
                     ATPase; putrescine transporting ATPase;
                     polyamine-transporting ATPase 13A3"
                     /codon_start=1
                     /product="polyamine-transporting ATPase 13A3 isoform 1"
                     /protein_id="NP_001121568.1"
                     /db_xref="CCDS:CCDS49821.1"
                     /db_xref="GeneID:224088"
                     /db_xref="MGI:MGI:2685387"
                     /translation="MDKEERKTINKGQEDEMEIHGYNLCRWKLAMVFVGVICTGGFLL
                     LLLYWLPEWRVKATCVRAAVKDCEVVLLRTTDEFRVWFCAKIHFLPVENQPNLNAKCL
                     VNEVSNGHAVHLTEENRCEMNKYSQSQSQQMRYFTHHSIRYFWNDAIHNFDFLKGLDE
                     GVSCASLYEKHSAGLTQGMHAYRKLIYGVNEIAVKVPSVFKLLIKEVLNPFYIFQLFS
                     VILWSVDEYYYYALAIVIMSVVSIISSLYSIRKQYVMLHDMVATHSTVRVSVCRENEE
                     IEEIFSTDLVPGDVMIIPLNGTVMPCDAVLINGTCIVNESMLTGESVPVTKTNLPNPS
                     VDVKGMGEEQYSPETHKRHTLFCGTTVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSI
                     LYPKPTDFKLYRDAYLFLLCLVVVAGIGFIYTIINSILNEKEVQEIIIKSLDIITITV
                     PPALPAAMTAGIVYAQRRLKKVGIFCISPQRINICGQLNLVCFDKTGTLTEDGLDLWG
                     IQRVENTRFLLPEDNVCSEMLVKSQFVACMATCHSLTKIEGVLSGDPLDLKMFEAIGW
                     ILEEATEEETALHNRIMPTVVRPSKQLLPEPTTAGNQEMELFELPAIYEIGIVRQFPF
                     SSALQRMSVVARTLGEKRMDAYMKGAPEVVASLCKPETVPVDFEKVLEDYTKQGFRVI
                     ALAHRKLESKLTWHKVQHISRDAIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRT
                     VMVTGDNMLTAVSVARDCGMILPQDKVIIAEALPPKDGKVAKINWHYTDSLSQCSESS
                     AIDSEAIPIKLAHDSLEDLEVTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMA
                     PDQKTQLVEALQNVDYFVGMCGDGANDCGALKRAHGGISLSELEASVASPFTSKTPSI
                     SCVPNLIREGRAALMTSFCVFKFMALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAII
                     LVVVFTMSLNPAWKELVAQRPPSGLISGALLFSVLSQIVISVGFQSLGFFWVKQYKVC
                     DPNSDVCNTTRSACWNSSHLYNGTELDSCKIQNYENTTVFFISSFQYLTVAVAFSKGK
                     PFRQPCYKNYFFVISVIILYVFILFIMLHPVASVDQVLEIMCVPYQWRIYMLIIVLIN
                     AFVSITVESFFLDTVLWKVVFNRDKQGECRFSTTQPPQESVDRWGKCCLSWALSCRKK
                     TPKAKYMYLAQELRFDPEWPPKPQTTTEAKAVVKENGSCQIITIA"
     exon            331..504
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            505..675
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            676..746
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            747..827
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            828..897
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1032
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1105
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..1237
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1417
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1575
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1764
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1765..1826
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1827..1977
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2094
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2095..2112
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2113..2266
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2267..2387
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..2512
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2513..2688
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2689..2811
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2812..2891
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2892..2934
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            2935..3044
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3141
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3142..3214
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3215..3383
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3384..3571
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..3660
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3661..3741
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3742..3831
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     exon            3832..7310
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7073..7078
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /note="hexamer: AATAAA"
     polyA_site      7096
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
     regulatory      7287..7292
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /note="hexamer: AATAAA"
     polyA_site      7310
                     /gene="Atp13a3"
                     /gene_synonym="Gm1745; Gm541; Gm542"
                     /note="major polyA site"
ORIGIN      
        1 ccgcgacgcg tggcggcgga ccctcgagcc cgagcgaccc gcggccgccg gcgccggccg
       61 tgggtgatgg ggctgggctg aggagaggcg gcggcggtgg cgaaagcggc cccccggccc
      121 cctgcggcct tttggctgcc cgggccggga ggccgcggag aaggcggcac ggcggcgcgg
      181 ctggtctgac agaagcaccc taggatcttg gtgtctggat acataagagt tatcttcacc
      241 tgttgtgtga agcatagcac ctttcaagcc actgtagaaa tggacaaaga agaaaggaag
      301 actatcaaca agggtcaaga agatgaaatg gagatacatg gctataactt atgccgctgg
      361 aagcttgcca tggtttttgt aggagtgatt tgtactggtg gttttctcct cctcctcctc
      421 tactggctgc ctgagtggcg agtgaaagcc acatgtgtta gagctgcagt taaagactgt
      481 gaagtggtgc ttctcaggac aactgatgaa tttagagtat ggttttgtgc aaaaattcac
      541 tttcttcctg tggagaatca accaaatttg aatgcaaaat gtttagttaa tgaggtttct
      601 aatggccatg ctgttcatct gactgaagaa aatagatgcg agatgaataa atactcacag
      661 agtcagtcac aacagatgcg ttattttacc caccatagca taagatattt ctggaatgat
      721 gccattcaca attttgattt cttaaaggga ctggatgaag gtgtatcttg tgcatcactt
      781 tatgaaaagc atagtgcagg actgacacag gggatgcatg cctacagaaa gttgatttat
      841 ggagtaaatg aaattgctgt gaaagtgcct tctgttttta agcttctaat taaagaggtt
      901 ctcaacccat tttacatttt ccagctcttc agtgttatcc tgtggagcgt tgatgagtac
      961 tattactatg ctctagccat tgtgatcatg tccgtagtat ccattataag ttcactatat
     1021 tccattagaa agcaatatgt tatgttacat gacatggtgg caactcacag taccgtgaga
     1081 gtttcagtct gtagagaaaa tgaagaaata gaagagatct tttctacaga ccttgtgccg
     1141 ggagacgtca tgatcattcc attaaatggg acagtcatgc cttgtgatgc agtacttatt
     1201 aatggtactt gcattgtaaa tgaaagcatg ttaacaggag aaagtgttcc agtgacaaag
     1261 actaatttgc caaatccttc agtggatgtg aaaggaatgg gggaggagca gtacagccca
     1321 gagacacaca agcggcacac tttgttttgt gggacgactg ttattcagac ccgtttctac
     1381 actggagaac ttgtgaaagc catagtagtt agaacaggat ttagtacttc caaaggacag
     1441 cttgttcgtt ctatactgta tcccaagcca actgacttta aactctatag agatgcctac
     1501 ttgtttctgc tgtgtcttgt ggtggtggct ggaattggat ttatctacac aatcatcaat
     1561 agcatcctaa atgagaaaga agttcaagaa ataattatta agtctcttga tatcattaca
     1621 attactgtgc cacctgctct tcctgctgca atgactgctg ggattgtgta tgctcagaga
     1681 agactgaaaa aagttgggat tttctgtatt agtccccaga ggataaacat ctgtggacag
     1741 ctgaaccttg tttgctttga caagactgga actcttaccg aagatggttt agatctgtgg
     1801 ggaattcagc gagtggaaaa tacccgattt cttttaccag aagacaatgt ttgcagtgag
     1861 atgttggtaa aatctcaatt tgttgcttgt atggctactt gtcattcact tacaaaaatc
     1921 gaaggtgtac tttctggtga cccacttgat ttgaaaatgt ttgaagccat tggatggatt
     1981 ctggaagaag caactgaaga agaaacagca cttcataacc ggatcatgcc tactgtggtt
     2041 cgtccttcca aacaactgct tcctgaacct acaactgcag gaaaccaaga aatggagctg
     2101 tttgaacttc cagctattta tgagatagga attgttcgcc agtttccatt ttcttctgcc
     2161 ttgcaacgga tgagtgtggt tgcaaggaca ctaggtgaga agaggatgga tgcctacatg
     2221 aagggggccc ctgaggttgt cgccagtctc tgcaaaccgg aaacagttcc agttgatttt
     2281 gagaaagtgt tagaagatta taccaaacaa ggtttccgtg taattgctct tgcacacaga
     2341 aaattggagt caaagctgac ctggcataaa gtacagcata ttagcagaga tgccattgaa
     2401 aacaacatgg attttatggg attgattata atgcagaaca aattgaagca ggaaacccct
     2461 gcagtacttg aagatttgca taaagccaac attcgaactg tcatggtcac aggagacaac
     2521 atgttgacgg ctgtctctgt ggccagagac tgtgggatga ttctacctca ggataaagtt
     2581 attattgctg aagcattacc tccaaaggat ggaaaagttg ccaagatcaa ttggcattat
     2641 acagactccc tgtcacagtg tagtgaatca tcagccattg actcagaggc tattccaatc
     2701 aaacttgccc atgatagttt agaggatctt gaggtgactc gctatcattt tgcgatgaat
     2761 ggaaagtcat tttcggtgat actggaacat tttcaagatc ttgttcctaa gttgatgttg
     2821 catggtactg tgtttgctcg aatggcaccg gatcagaaga cacaattggt ggaggcattg
     2881 cagaacgtag actactttgt tgggatgtgc ggtgatggtg caaatgattg tggtgctttg
     2941 aagagggcac atggtggcat ttccttatct gagcttgaag cttccgtggc atctcctttt
     3001 acttctaaga cacccagtat ctcctgtgtg ccaaacctta tcagggaagg tcgtgctgct
     3061 ttaatgacgt ccttctgtgt gtttaaattt atggcgttat acagcatcat ccagtacttc
     3121 agtgttactc tcctgtattc tatcttgagt aacctgggag actttcagtt tctcttcatt
     3181 gatctggcaa tcattttggt agtagtattt acaatgagtt taaatcctgc ctggaaagag
     3241 cttgtggcac agagaccacc ttcaggcctt atatctgggg cgctcctctt ctccgtcttg
     3301 tctcagattg tgatctccgt tggatttcag tcgctgggtt ttttctgggt caagcagtat
     3361 aaagtgtgcg atccaaattc agatgtttgt aatacaacaa gaagcgcatg ttggaactcg
     3421 tcacacttat acaatgggac tgaactcgat tcgtgtaaaa tacaaaatta tgaaaatacc
     3481 acagtatttt ttatctccag tttccagtac ctcacagtgg cggttgcctt ttcaaaagga
     3541 aaaccattca ggcagccttg ctacaagaat tatttttttg ttatatctgt gattattttg
     3601 tatgttttca tattattcat catgttgcat ccagttgcct ctgttgacca ggttcttgag
     3661 attatgtgtg taccatacca gtggcgcata tatatgctta tcattgttct tatcaatgcc
     3721 ttcgtgtcta tcacggtgga gagcttcttc cttgacacgg tcctttggaa agttgtattc
     3781 aatcgagaca aacaaggaga gtgtcgtttc agcaccacac agccaccaca ggagtcagtg
     3841 gatcggtggg gaaaatgctg tttgtcctgg gccctgagct gtagaaagaa aactccaaaa
     3901 gcaaagtaca tgtacttagc acaggagctc cgctttgatc ctgagtggcc gcctaaacct
     3961 cagacaacga cggaagccaa agctgtagta aaggagaatg gatcatgtca gattatcacc
     4021 atagcataac aaaggctgct ctctgtgcta gtagcagtgc tcagcagcat gcactgttga
     4081 gcttttctga cgctgtgtca gaatggcact agttcagttt atatccctct cataatatgg
     4141 cagttcatta aaatacaaag cagtaaaatg tcatttgctg tacgattatt aactataaat
     4201 ctggctattt cttcatccag taacctaaat atgatatata ctttatattg ggtatgagag
     4261 atctgtgttt gggttttata gattttagct tttgacacgt ttgcctcttt aaatttactt
     4321 ttcataaatc cccttattag aaagttcttt tacatatagg ccccaaaatt gtgattatta
     4381 aaaatatagt taattgtgat tagcctccag tgaaaatagg ttgaaagcct gttttgatcc
     4441 agtgttttct cccaaagaac tctacgttaa acatacacca gttttctttt atgacctgga
     4501 gttaggagtg agtttgtgtg ttgttgatag agcaactcag gtaatttcca tttctggttt
     4561 tatattctct gtatctcctg cctgggtgtc actttctaga cagtaaggcg ctccactgct
     4621 tgctgtctga gatatccttc atagtattcc atggctccca tactgcagtc tagttaagca
     4681 aagaactctc actagaaagg tttatttcag ccgggtgtgg tggtggtgca cgcctttaat
     4741 cccagcattc gggagggagg caggggcagg cggatttcta aattccagga cagcctgggc
     4801 tatacagaga aaccctgtct tgaacccccc ccccccccgc cacccccaaa aaaaggttta
     4861 tttctgagca gccaggcatg ataagtaaag gcccctagtc ctgcacagga ggctgaggca
     4921 ggagaattgt ttagtcctgg aatagatagt aaaagcctgt ctcagaatac acaagcagag
     4981 aaggatcggg gttatgtctc ttggcagtag atcccattca tacctcttca aacctatttg
     5041 ttttttttct tttgggactt atatgatttt aaatatttca tattctccct cccactccta
     5101 ctctccctcc ttccctctct ccatcccttc ctcctaccta aaggaatgga atgatgctgt
     5161 ttttgttttg agtttgacct taaccttgct atgtctctcc tttgaataat ggggcttaaa
     5221 agaataatga acatggaatt tgaattactt ttacaaagca atatgaactt gtagagcttg
     5281 tcttgtgcca ttaggtggca ccagagatca tcacatacct attttgtaac aagtgagctt
     5341 gagaaaatta agaaaatata tacatttatt tagccaaaag gaatgaagaa agcatttaca
     5401 catttgtgtt ttatctgatt ctgttcagtt ctcaaggaac tttcacaatg ctttcctagg
     5461 taggacctgg cagtttggca gtgccttcag tttagcattg ctataaaatg aaccctgaat
     5521 tagcgaaaca gtgtaacatt attctgtgtt ctttattagc taactacaag tgtatgcttt
     5581 ccactctggt tgatcattag ttccctagta catacttaaa agtttaccaa atgttaacca
     5641 gatttttgaa acctcccccc ccccctattt atttattttt tatgttggaa atacccgaat
     5701 gatgtttggt aattgtagaa aaagtaaatg tgtctcagga tcactattac tgctgttgcc
     5761 actagtgatt cctaggaaat acataattga ctttttccaa caaaatgtat attattacat
     5821 gttagataat aagaacaatt gtcccgtgaa tgattctatg aagctatgca tcttagacct
     5881 cttgagctgt gaattagcac tattttctat ggttacttat tatctattgt tttatacttt
     5941 ctatgttcat ttcaaataat gttaatgtta ttcaatcatt ttctgaattg ttaactctta
     6001 ttctttggtt taaatactga aacatgatta attgctaact acagcttaga aacccaatat
     6061 cagttgtact taacatcttt aagagcatga tcataaaggc tattttgaca gttcatttta
     6121 acatttagag ttgataaggg tttatatctc atctgtccat attgtttgca aaggaacaag
     6181 gttttatgta ggtgagagaa agcatttgta cgaagttaga tttgaacata gataagatag
     6241 gttattccag ttgagaatat tgttcgaaga atgtctgtga atgcagacat gggtcctgct
     6301 tagtgccata ggtagactga gtcttctgta agtcatcatt acatagtaat tttggttctg
     6361 aattttacat taaattattt gaatatatac agacctaaat tttaaaatct gtacatatat
     6421 tattttgatg tattaagatt gataatattg ctgatttaaa ttttatttat gcacatactt
     6481 aaaggacaga aatgtctggt aaagtaattg ttaaataatg atatgtagct ttttaacttt
     6541 ttaaataaat aagatttttt aatgtgggtc tccctcaggg ttgtttaaag ttgtttgttt
     6601 tcctccctta catataaata aataatggta accggtttct atcttgtagc accaactgct
     6661 gtaagggaat gctgcagaca gtgcttgggc gagtgtggcg ccaacaagcc tgagattcaa
     6721 acgctttcca tttaagcaaa cctcttcttg tttttatact tcattttgtt tcccatgttg
     6781 atgaaagtac tgcacagttt caaaggcatg gtaaataatg tgtttctttc atatatattt
     6841 ttttccaaaa gcagcaaaaa ttcatatcca gtgaagatca acttcaagct ttagagaaca
     6901 tctaatatct catgcatgca gttttgttgt atcaattaaa agggttttgt atatttatgg
     6961 tgggaggcta ctgggaactt ttaacaaaat agggaattaa cttttgtaca gtctgggcat
     7021 ttacatgtat ttttaatgta ttacaatttg gtaattatgt gcacatgaaa ttaataaaag
     7081 ttacttcctg ttataatttg tgaattccct gagaccgtgg atttttttta agtaacttta
     7141 tatatcagaa atgacacatc tttatatttt taaaattgta ttgctgctca agaatggtac
     7201 ccttttgtca aaaaggtaga tattcataat tgtacattca gcattgtaaa taccatatga
     7261 aatccttttt gattaaagct attcaaaata aaaaatttta atgaattaaa
//
