LOCUS       NM_029097               3908 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus ATPase type 13A2 (Atp13a2), transcript variant 1,
            mRNA.
ACCESSION   NM_029097 XM_915160
VERSION     NM_029097.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3908)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3908)
  AUTHORS   Zhang,F., Wu,Z., Yu,B., Ning,Z., Lu,Z., Li,L., Long,F., Hu,Q.,
            Zhong,C., Zhang,Y. and Lin,C.
  TITLE     ATP13A2 activates the pentose phosphate pathway to promote
            colorectal cancer growth though TFEB-PGD axis
  JOURNAL   Clin Transl Med 13 (5), e1272 (2023)
   PUBMED   37243374
  REMARK    GeneRIF: ATP13A2 activates the pentose phosphate pathway to promote
            colorectal cancer growth though TFEB-PGD axis.
REFERENCE   3  (bases 1 to 3908)
  AUTHORS   Gao,H., Sun,H., Yan,N., Zhao,P., Xu,H., Zheng,W., Zhang,X.,
            Wang,T., Guo,C. and Zhong,M.
  TITLE     ATP13A2 Declines Zinc-Induced Accumulation of alpha-Synuclein in a
            Parkinson's Disease Model
  JOURNAL   Int J Mol Sci 23 (14), 8035 (2022)
   PUBMED   35887392
  REMARK    GeneRIF: ATP13A2 Declines Zinc-Induced Accumulation of
            alpha-Synuclein in a Parkinson's Disease Model.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3908)
  AUTHORS   Johnson,M.E., Bergkvist,L., Stetzik,L., Steiner,J.A., Meyerdirk,L.,
            Schulz,E., Wolfrum,E., Luk,K.C., Wesson,D.W., Krainc,D. and
            Brundin,P.
  TITLE     Heterozygous GBA D409V and ATP13a2 mutations do not exacerbate
            pathological alpha-synuclein spread in the prodromal preformed
            fibrils model in young mice
  JOURNAL   Neurobiol Dis 159, 105513 (2021)
   PUBMED   34536552
  REMARK    GeneRIF: Heterozygous GBA D409V and ATP13a2 mutations do not
            exacerbate pathological alpha-synuclein spread in the prodromal
            preformed fibrils model in young mice.
REFERENCE   5  (bases 1 to 3908)
  AUTHORS   Wang,R., Tan,J., Chen,T., Han,H., Tian,R., Tan,Y., Wu,Y., Cui,J.,
            Chen,F., Li,J., Lv,L., Guan,X., Shang,S., Lu,J. and Zhang,Z.
  TITLE     ATP13A2 facilitates HDAC6 recruitment to lysosome to promote
            autophagosome-lysosome fusion
  JOURNAL   J Cell Biol 218 (1), 267-284 (2019)
   PUBMED   30538141
REFERENCE   6  (bases 1 to 3908)
  AUTHORS   Ramonet,D., Podhajska,A., Stafa,K., Sonnay,S., Trancikova,A.,
            Tsika,E., Pletnikova,O., Troncoso,J.C., Glauser,L. and Moore,D.J.
  TITLE     PARK9-associated ATP13A2 localizes to intracellular acidic vesicles
            and regulates cation homeostasis and neuronal integrity
  JOURNAL   Hum Mol Genet 21 (8), 1725-1743 (2012)
   PUBMED   22186024
  REMARK    GeneRIF: study reveals a number of intriguing neuronal phenotypes
            due to the loss- or gain-of-function of ATP13A2 that support a role
            for this protein in regulating intracellular cation homeostasis and
            neuronal integrity
REFERENCE   7  (bases 1 to 3908)
  AUTHORS   Usenovic,M., Tresse,E., Mazzulli,J.R., Taylor,J.P. and Krainc,D.
  TITLE     Deficiency of ATP13A2 leads to lysosomal dysfunction,
            alpha-synuclein accumulation, and neurotoxicity
  JOURNAL   J Neurosci 32 (12), 4240-4246 (2012)
   PUBMED   22442086
REFERENCE   8  (bases 1 to 3908)
  AUTHORS   Gusdon,A.M., Zhu,J., Van Houten,B. and Chu,C.T.
  TITLE     ATP13A2 regulates mitochondrial bioenergetics through
            macroautophagy
  JOURNAL   Neurobiol Dis 45 (3), 962-972 (2012)
   PUBMED   22198378
  REMARK    GeneRIF: This study showed that ATP13A2 regulates mitochondrial
            bioenergetics through macroautophagy.
REFERENCE   9  (bases 1 to 3908)
  AUTHORS   Abdallah,B.M., Ditzel,N., Mahmood,A., Isa,A., Traustadottir,G.A.,
            Schilling,A.F., Ruiz-Hidalgo,M.J., Laborda,J., Amling,M. and
            Kassem,M.
  TITLE     DLK1 is a novel regulator of bone mass that mediates estrogen
            deficiency-induced bone loss in mice
  JOURNAL   J Bone Miner Res 26 (7), 1457-1471 (2011)
   PUBMED   21308776
REFERENCE   10 (bases 1 to 3908)
  AUTHORS   Schultheis,P.J., Hagen,T.T., O'Toole,K.K., Tachibana,A.,
            Burke,C.R., McGill,D.L., Okunade,G.W. and Shull,G.E.
  TITLE     Characterization of the P5 subfamily of P-type transport ATPases in
            mice
  JOURNAL   Biochem Biophys Res Commun 323 (3), 731-738 (2004)
   PUBMED   15381061
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645625.15.
            
            On Apr 9, 2020 this sequence version replaced NM_029097.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC042661.1, AK156104.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               AL645625.15        69685-69840
            157-251             AL645625.15        74896-74990
            252-434             AL645625.15        75102-75284
            435-493             AL645625.15        76560-76618
            494-608             AL645625.15        76712-76826
            609-688             AL645625.15        77076-77155
            689-766             AL645625.15        78090-78167
            767-836             AL645625.15        78322-78391
            837-971             AL645625.15        79066-79200
            972-1038            AL645625.15        79288-79354
            1039-1170           AL645625.15        79432-79563
            1171-1326           AL645625.15        81892-82047
            1327-1437           AL645625.15        83107-83217
            1438-1484           AL645625.15        83307-83353
            1485-1673           AL645625.15        83449-83637
            1674-1880           AL645625.15        84648-84854
            1881-1970           AL645625.15        85221-85310
            1971-2130           AL645625.15        85388-85547
            2131-2251           AL645625.15        85663-85783
            2252-2376           AL645625.15        85915-86039
            2377-2537           AL645625.15        86650-86810
            2538-2642           AL645625.15        86946-87050
            2643-2722           AL645625.15        87132-87211
            2723-2875           AL645625.15        87766-87918
            2876-2972           AL645625.15        88030-88126
            2973-3196           AL645625.15        88807-89030
            3197-3348           AL645625.15        89116-89267
            3349-3518           AL645625.15        89443-89612
            3519-3908           AL645625.15        89705-90094
FEATURES             Location/Qualifiers
     source          1..3908
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 73.29 cM"
     gene            1..3908
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /note="ATPase type 13A2"
                     /db_xref="GeneID:74772"
                     /db_xref="MGI:MGI:1922022"
     exon            1..156
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..3656
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /EC_number="7.2.2.10"
                     /note="isoform 1 is encoded by transcript variant 1;
                     probable cation-transporting ATPase 13A2;
                     polyamine-transporting ATPase 13A2"
                     /codon_start=1
                     /product="polyamine-transporting ATPase 13A2 isoform 1"
                     /protein_id="NP_083373.2"
                     /db_xref="CCDS:CCDS18859.1"
                     /db_xref="GeneID:74772"
                     /db_xref="MGI:MGI:1922022"
                     /translation="MSADSSLLMGSTPPSYGTLTTGTSIDPLSSSASSVRLSGYCGSP
                     WRAIGYHAAVWMLAGIPWLLFRWKPLWGVRLRLKPCSLAHAETLVIEIKDKEGSSRQL
                     FTVQVQTEAVVQGSLELPPQAQAEDGRSQAAVGVTPEGTWQDTSELHRQEEAKQVLRY
                     YVLQGQRYVWMETQQAFCQVSLLDHGRTCDDVHCSSSGLSLQDQATRKTIYGPNVISI
                     PVKSYLQLLADEALNPYYGFQAFSIALWLADHYYWYALCIFLISAISICLALYKTRKQ
                     SLTLRDMVKLSVRVQVCRPGGEEEWVDSSELVPGDCLVLPQEGGVMPCDAALVAGECV
                     VNESSLTGESTPVLKTALPEGPKPYCPETHRRHTLFCGTLILQARAYVGPRVLAVVTR
                     TGFCTAKGGLVSSILHPRPISFKFYKHSMKFVAALSVLALLGTVYSIIILYRNRVPVR
                     EIVIRALDLVTVVVPPALPAAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKLRLVCFD
                     KTGTLTEDGLDVMGVVPLKGQVLLPLVPEPCHLPLGPLLRALATCHALSQLHDTPVGD
                     PMDLKMVESTGWVLEEGPAAGSAPGSQVLVVMRPPPGGPRQQEEPPVPVSVLCRFPFS
                     SALQRMDVVVTWPGATQPEAYVKGSPELVASLCSPETVPSDFSQVLQSYTAAGYRVVA
                     LAGKPLPIAPSLAAAQQLTRDTVERELSLLGLLVMRNLLKPQTAPVIQTLRKTGIRTV
                     MVTGDNLQTAVTVARACGMVGAQEHLAVIHATHPEQGQPAALEFLPTESSAVMNGAKA
                     TGYPTVPEPQSCHLALSGSTFAVLRKHFPKLLPKVLVQATVFARMAPEQKTELVCELQ
                     RLQYCVGMCGDGANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVPTVIREGRC
                     SLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGP
                     ALTLVRARPPGALLSVPVLGSLLLQVALVAGIQLGGYFLVIAQPWFVPLNRTVPAPDN
                     LPNYENTVVFSLSGFQYLILAAAVSKGAPFRQPLYTNVPFLVALALLGSVLVGLILVP
                     GLLQGPLGLRNIVDSSFKLLLLGLVAFNFVGAFMLESVLDQCLPACLRWLRPKRASKK
                     QFKRLQQELAEHPWPTLPVGSVR"
     exon            157..251
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            252..434
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            435..493
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            494..608
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            609..688
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            689..766
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            767..836
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            837..971
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1038
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1170
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1326
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1437
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1484
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..1673
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1880
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1881..1970
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1971..2130
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2131..2251
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2252..2376
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2537
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2642
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2643..2722
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2723..2875
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..2972
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2973..3196
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3197..3348
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3349..3518
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3519..3908
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3887..3892
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3908
                     /gene="Atp13a2"
                     /gene_synonym="1110012E06Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtcgccgtc gcgtcttgca ggtgctgccc agcccggccc ctccgcggat cgccgcaacc
       61 ggcgcccccc gaccgtgccc cggggcctcg cacgccgagc ccaggccgcg ggccacagcg
      121 gccggcgatg agcgcgagga gccgaaatga gcgcagacag cagcctgctc atgggcagca
      181 cgccccccag ctatgggacc ctgacgacag ggacgtcaat cgatcccctc agctcctcag
      241 cttcatccgt gaggctcagc ggctactgtg gcagtccatg gagggccatc ggctatcacg
      301 ccgcggtctg gatgctggcc gggatccctt ggctgctatt ccgctggaag cccttgtggg
      361 gcgtgcgcct gcgcctgaag ccatgcagcc tggcccacgc cgaaacactc gttatagaaa
      421 taaaagacaa agagggtagc tccagacagc tcttcacggt tcaggtgcag actgaggctg
      481 ttgttcaggg cagcctggag ctgcccccac aggcccaggc agaggatggc cggagccagg
      541 cagccgtggg agtgacacca gagggcacat ggcaggacac ctccgaactc cacaggcagg
      601 aagaggcaaa gcaggtactg cgctattatg tcctccaagg tcaacgctac gtctggatgg
      661 aaacccagca agccttctgc caagtcagcc tgctggacca cggtcgtacc tgtgatgacg
      721 tccactgctc cagctccggc ctcagcctcc aggaccaagc tacgaggaag accatttacg
      781 gccccaacgt gatcagtatt cctgtcaagt cctacctgca gctgctggcg gatgaggccc
      841 tgaatcccta ctatgggttc caagccttca gcatcgcact gtggctggcc gaccactact
      901 actggtatgc tctctgcatc ttcctcatct cagccatctc catctgcctg gctctgtaca
      961 agaccagaaa gcaaagcttg accttgaggg acatggtcaa gctgtccgtg cgggtgcagg
     1021 tgtgccgacc cggaggagag gaagagtggg tggactccag tgagctggtg cccggagact
     1081 gcttggtgct gccccaggag ggcggggtga tgccatgcga cgcggctctg gtggccgggg
     1141 agtgtgtggt caacgagagc tccctgacag gggagagcac ccctgtgctg aagacggccc
     1201 tgccagaggg gcccaagccc tactgcccag agacccaccg gcggcacacc ctcttctgtg
     1261 gcaccctcat tctgcaggcc cgagcctacg tgggaccccg tgtgctagca gtggtgactc
     1321 ggacagggtt ctgcacagcc aaagggggcc tggtgagctc catcctgcac ccaaggccca
     1381 tcagcttcaa gttctacaaa cacagcatga agtttgtggc tgcgctctcc gtcctggctc
     1441 tgctaggcac cgtctacagc atcatcatcc tctaccgcaa ccgggtacct gtgagggaga
     1501 ttgtgatccg agctctggac ctggtgacgg tggtggtgcc gcccgccctg cctgccgcca
     1561 tgaccgtgtg cacactctat gcccagagtc ggctgcgcac acagggcatc ttctgcatcc
     1621 acccactgcg catcaacttg gggggcaagc tgcggctcgt gtgctttgac aagacaggca
     1681 ccctcacgga ggacggcttg gacgtaatgg gcgtggtgcc cctaaagggg caggtgttgc
     1741 tgccactggt cccagagccc tgccacctgc ccctggggcc cctcctgcga gcactggcca
     1801 cctgtcatgc cctcagccag ctacatgaca ccccggtggg cgaccccatg gatctgaaga
     1861 tggtggagtc tacaggctgg gtcttagagg agggtccagc tgcaggctca gcacctggga
     1921 gccaggtctt ggtggtaatg agacccccac ccgggggccc tcggcagcag gaagagccac
     1981 cagtgccagt cagcgtcctc tgccgcttcc ccttctcctc tgccctgcag cggatggatg
     2041 tggtagtgac atggccaggg gccacccagc ctgaggccta cgtcaaaggc tccccagagc
     2101 ttgtggccag cctctgcagc cccgagacag tacccagcga cttttctcag gtgctgcaga
     2161 gctacacagc tgctggctac cgagttgtgg ccctggctgg caagccactg cccattgcgc
     2221 ccagccttgc ggccgctcag cagctaacaa gggatactgt ggagcgggaa ctgagcctcc
     2281 tggggctgct ggtcatgcgg aacctactga agccacagac ggccccagtt atccagactc
     2341 tgaggaagac gggcatccgc accgttatgg tgacagggga caacctgcag acagcagtca
     2401 ccgtggccag agcttgtggc atggtgggcg cccaggagca cctggctgtc atccatgcca
     2461 cccaccccga gcagggccag cctgctgccc tcgagttcct gccaacggag tcctctgcag
     2521 tcatgaacgg ggcgaaggcc acaggctatc ccacggtgcc ggaaccccag tcctgtcacc
     2581 tggccctcag cgggtccacg tttgcagtcc ttcggaagca cttccccaag ctgctgccca
     2641 aggtcctggt gcaggctacc gtctttgccc gaatggcccc ggagcagaag acagagctag
     2701 tgtgcgaact gcagaggctt cagtactgtg tgggcatgtg cggggatgga gccaacgact
     2761 gtggggccct gaaggcggct gatgtgggca tatcgctgtc ccaggcggag gcgtcagtgg
     2821 tctctccgtt cacctccagc atggccagta ttgaatgtgt gcccactgtc atcagggaag
     2881 gccgctgctc cctggatact tcattcagcg tcttcaagta catggccctc tacagcctga
     2941 ctcagttcat ctctgtgctc attctctaca caatcaacac caacctggga gacctacagt
     3001 tcttggccat tgacctggtc atcaccacca cggttgcggt gctcatgagc cgcacaggcc
     3061 ctgcactgac cttggtgcga gcgcggccgc caggggcgct gctgagtgtg cctgtgcttg
     3121 gcagtctgct gctgcaggtg gccttggtgg ccggcatcca gctggggggc tactttttgg
     3181 tcatagctca gccctggttt gtgcctctga acagaactgt gcccgctccg gacaacctgc
     3241 ccaactacga gaatacggtg gtcttctctc tgtctggctt ccagtacctc atcctggccg
     3301 cagcggtgtc taagggggca cccttccgcc agccactcta caccaacgtg cccttcctgg
     3361 tggccctggc gctcttgggc tctgtcctgg tgggcctcat cctggtcccc ggcctcctgc
     3421 aggggcccct aggactgagg aacattgtgg acagctcctt caagctactg ctgctgggtc
     3481 tggtcgcctt caacttcgtc ggcgccttta tgctggagag cgtgctggac cagtgtctcc
     3541 cagcctgcct gcggtggctg cggcctaaac gggcctccaa gaagcaattc aagcggctgc
     3601 aacaggagct tgcagaacat ccatggccca ctctgcccgt tggctccgtg aggtagtgca
     3661 ggccttggag ggcatgctgg acactggatc tccctgcccc tgagccacga ctggaactct
     3721 ctcaagagac agtaccagtc acctcccaca gccctgaagc tggctgctgt cacactgctg
     3781 tccggacaca ctctcctggg gaagtgctga ctgctgtctc actttagacc atcctgtgta
     3841 gagatagcag ctaccaactc catccagagc tgctggcact ataacaaata aagtgctggc
     3901 tttcctga
//
