LOCUS       NM_001293667            7547 bp    mRNA    linear   ROD 31-JUL-2024
DEFINITION  Mus musculus ATPase, class VI, type 11A (Atp11a), transcript
            variant 2, mRNA.
ACCESSION   NM_001293667 XM_006508835 XM_006508836
VERSION     NM_001293667.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7547)
  AUTHORS   Martinez-Mayer,J., Brinkmeier,M.L., O'Connell,S.P., Ukagwu,A.,
            Marti,M.A., Miras,M., Forclaz,M.V., Benzrihen,M.G., Cheung,L.Y.M.,
            Camper,S.A., Ellsworth,B.S., Raetzman,L.T., Perez-Millan,M.I. and
            Davis,S.W.
  TITLE     Knockout mice with pituitary malformations help identify human
            cases of hypopituitarism
  JOURNAL   Genome Med 16 (1), 75 (2024)
   PUBMED   38822427
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7547)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 7547)
  AUTHORS   Chepurwar,S., von Loh,S.M., Wigger,D.C., Neef,J., Frommolt,P.,
            Beutner,D., Lang-Roth,R., Kubisch,C., Strenzke,N. and Volk,A.E.
  TITLE     A mutation in ATP11A causes autosomal-dominant auditory neuropathy
            type 2
  JOURNAL   Hum Mol Genet 32 (7), 1083-1089 (2023)
   PUBMED   36300302
  REMARK    GeneRIF: A mutation in ATP11A causes autosomal-dominant auditory
            neuropathy type 2.
REFERENCE   4  (bases 1 to 7547)
  AUTHORS   Radford,B.N., Zhao,X., Glazer,T., Eaton,M., Blackwell,D.,
            Mohammad,S., Lo Vercio,L.D., Devine,J., Shalom-Barak,T.,
            Hallgrimsson,B., Cross,J.C., Sucov,H.M., Barak,Y., Dean,W. and
            Hemberger,M.
  TITLE     Defects in placental syncytiotrophoblast cells are a common cause
            of developmental heart disease
  JOURNAL   Nat Commun 14 (1), 1174 (2023)
   PUBMED   36859534
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7547)
  AUTHORS   Miyata,Y., Yamada,K., Nagata,S. and Segawa,K.
  TITLE     Two types of type IV P-type ATPases independently re-establish the
            asymmetrical distribution of phosphatidylserine in plasma membranes
  JOURNAL   J Biol Chem 298 (11), 102527 (2022)
   PUBMED   36162506
  REMARK    GeneRIF: Two types of type IV P-type ATPases independently
            re-establish the asymmetrical distribution of phosphatidylserine in
            plasma membranes.
REFERENCE   6  (bases 1 to 7547)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   7  (bases 1 to 7547)
  AUTHORS   Halleck,M.S., Schlegel,R.A. and Williamson,P.L.
  TITLE     Reanalysis of ATP11B, a type IV P-type ATPase
  JOURNAL   J Biol Chem 277 (12), 9736-9740 (2002)
   PUBMED   11790799
REFERENCE   8  (bases 1 to 7547)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   9  (bases 1 to 7547)
  AUTHORS   Halleck,M.S., Lawler,J.F. Jr., Blackshaw,S., Gao,L., Nagarajan,P.,
            Hacker,C., Pyle,S., Newman,J.T., Nakanishi,Y., Ando,H.,
            Weinstock,D., Williamson,P. and Schlegel,R.A.
  TITLE     Differential expression of putative transbilayer amphipath
            transporters
  JOURNAL   Physiol Genomics 1 (3), 139-150 (1999)
   PUBMED   11015572
  REMARK    Publication Status: Online-Only
REFERENCE   10 (bases 1 to 7547)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147497.1 and AC134581.5.
            
            On or before Jun 12, 2014 this sequence version replaced
            XM_006508836.1, XM_006508835.1.
            
            Transcript Variant: This variant (2) contains an alternate exon in
            the 3' end compared to variant 1. The resulting isoform (2) has a
            shorter and distinct C-terminus compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147497.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2910              AK147497.1         4-2913
            2911-2911           AC134581.5         157758-157758
            2912-3689           AK147497.1         2914-3691
            3690-4063           AK147497.1         3693-4066
            4064-4064           AC134581.5         175181-175181
            4065-7547           AK147497.1         4068-7550
FEATURES             Location/Qualifiers
     source          1..7547
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 5.73 cM"
     gene            1..7547
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /note="ATPase, class VI, type 11A"
                     /db_xref="GeneID:50770"
                     /db_xref="MGI:MGI:1354735"
     exon            1..337
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..3727
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /EC_number="7.6.2.1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     probable phospholipid-transporting ATPase IH; ATPase,
                     class 1, member h; ATPase 11A, p type; ATPase 11A, class
                     VI; P4-ATPase flippase complex alpha subunit ATP11A;
                     9130422H11Rik"
                     /codon_start=1
                     /product="phospholipid-transporting ATPase IH isoform 2"
                     /protein_id="NP_001280596.1"
                     /db_xref="CCDS:CCDS80858.1"
                     /db_xref="GeneID:50770"
                     /db_xref="MGI:MGI:1354735"
                     /translation="MDCSLLRTLVRRYCAGEENWVDSRTIYVGHKEPPPGAEAYIPQR
                     YPDNRIVSSKYTFWNFIPKNLFEQFRRIANFYFLIIFLVQLIIDTPTSPVTSGLPLFF
                     VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETF
                     PCDLIFLSSNRADGTCHVTTASLDGESSHKTHYAVQDTKGFHTEADVDSLHATIECEQ
                     PQPDLYKFVGRINVYNDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMA
                     LNYQSKSQKRSAVEKSMNTFLIVYLCILVSKALINTVLKYVWQSEPFRDEPWYNEKTE
                     SERQRNLFLRAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEEMGE
                     GPLVNTSDLNEELGQVEYIFTDKTGTLTENNMAFKECCIEGHVYVPHVICNGQVLPDS
                     SGIDMIDSSPGVCGREREELFFRAICLCHTVQVKDDHCGDDVDGPQKSPDAKSCVYIS
                     SSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENDIERFELLEVLTFDSVRRRMSVIV
                     KSTTGEIYLFCKGADSSIFPRVIEGKVDQVRSRVERNAVEGLRTLCVAYKRLEPEQYE
                     DACRLLQSAKVALQDREKKLAEAYEQIEKDLVLLGATAVEDRLQEKAADTIEALQKAG
                     IKVWVLTGDKMETASATCYACKLFRRSTQLLELTTKKLEEQSLHDVLFDLSKTVLRCS
                     GSMTRDSFSGLSTDMHDYGLIIDGAALSLIMKPREDGSSSGNYRELFLEICRNCSAVL
                     CCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGKEGRQAARN
                     SDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCGFSQQTL
                     YDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDIAKNALLRWRVFIYWT
                     FLGVFDALVFFFGAYFIFENTTVTINGQMFGNWTFGTLVFTVMVLTVTLKLALDTHYW
                     TWINHFVIWGSLLFYIAFSLLWGGVIWPFLSYQRMYYVFISMLSSGPAWLGIILLVTV
                     GLLPDVLKKVLCRQLWPTATERTQQSTRLKALADATSNSARPLLKDFLPQPRHV"
     exon            338..460
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            461..550
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            551..631
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            632..739
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            740..868
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            869..972
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1023
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1088
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1170
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1321
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1519
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1520..1693
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1694..1863
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1864..1935
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            1936..2009
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2113
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2295
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            2296..2547
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            2548..2725
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            2726..2828
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            2829..2974
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            2975..3034
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            3035..3162
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            3163..3298
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            3299..3364
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            3365..3468
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            3469..3634
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            3635..3738
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     exon            3739..7547
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7528..7533
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /note="hexamer: ATTAAA"
     polyA_site      7547
                     /gene="Atp11a"
                     /gene_synonym="4930558F19Rik; Atpc1h; Ih"
                     /note="major polyA site"
ORIGIN      
        1 gcgcccgtga cgcgcggggc gcagcggggc agagccggct ccagaggcgc ggcggccgcg
       61 ggaggagcag gcgcggagca tcgagcgcag gccgcgtcgg cccgacggga gtagcgccgg
      121 gcgcaggccg cctcctccga gccgcctgcg cgcgggccga gacccttggc cgccgccggc
      181 ggggcatgag cgcggagggg ccgcggccgc cccccgcgcc gcccaggccg tgaccgggcg
      241 gggggcggct gcgctagcgc ccgcagccca ggggctcgcg gagccgggag cgataaccat
      301 ggactgcagt ctattgagga cgctcgtgcg cagatactgt gcaggggaag agaactgggt
      361 ggacagtcgg accatctacg tgggacacaa ggagccccct ccgggtgcag aggcctacat
      421 tccacagaga taccccgaca atagaatcgt ctcctccaag tacacattct ggaacttcat
      481 acccaagaac ttatttgaac agttcagaag aatagccaac ttttatttcc tcatcatctt
      541 cctggtacag ttgatcatcg acacacccac aagtccagtg acaagcgggc tcccactctt
      601 cttcgtcatc actgtcacgg ccatcaagca gggctatgaa gactggcttc gccacaaggc
      661 cgacaacgcc atgaaccagt gtcccgtgca ctttatccag catggcaagc tggtccgcaa
      721 gcagagtcgg aagctgaggg ttggggacat tgtcatggtg aaggaagatg agacctttcc
      781 ctgtgacctg atctttctct ccagcaaccg ggcagatggg acatgccatg tcactacagc
      841 cagcttagac ggagagtcga gccataaaac tcactacgca gtgcaggata ccaagggctt
      901 ccacacagag gcggatgttg acagcttgca cgccacgatc gagtgtgaac agccacagcc
      961 tgacctctac aagtttgtgg ggcgcatcaa tgtttacaac gacctgaacg accctgtagt
     1021 gaggcctttg gggtcagaaa acctgcttct cagaggagcc acactcaaaa acacagagaa
     1081 gatctttggt gtggctatct acacaggcat ggagaccaag atggccctga actatcaatc
     1141 caagtcccaa aagagatctg ctgtggaaaa gtcaatgaac acattcctga tcgtgtacct
     1201 ctgcatcctg gtgagcaagg ccctgatcaa cacggtgctg aagtacgtgt ggcagagtga
     1261 gcccttccga gatgagccat ggtacaacga gaagaccgaa tccgagcgcc agaggaattt
     1321 gttcctcagg gccttcaccg acttcctggc cttcatggtc ctcttcaatt acatcatccc
     1381 cgtatccatg tacgtcaccg tggagatgca gaagttcctc ggctcctact tcatcacctg
     1441 ggatgaggac atgtttgatg aggaaatggg ggaagggcct ctggtcaaca catctgatct
     1501 gaatgaggag ttgggacagg tggaatacat cttcactgac aagaccggca cgcttacaga
     1561 gaacaacatg gccttcaagg agtgctgcat cgagggccat gtctacgtac cccatgtcat
     1621 ctgcaatggg caggtccttc ccgactcttc tggcattgac atgatcgatt cttcccccgg
     1681 agtctgtgga agggaacggg aggagctgtt tttcagggcc atctgcctgt gccacactgt
     1741 ccaagtgaaa gatgaccatt gtggggatga tgtcgatggt ccccagaaat ctccagatgc
     1801 aaaatcctgt gtgtacatat cgtcctcgcc tgatgaggtt gcactggtcg aaggcgtgca
     1861 gaggcttgga ttcacgtacc tgaggctgaa ggacaattac atggaaatac tgaacaggga
     1921 gaacgacata gagagatttg aattgctaga agtgctgacc tttgattctg tgcggagaag
     1981 aatgagtgtg attgtaaagt ctactacagg agaaatttat ctgttttgca aaggagcaga
     2041 ttcttcaata tttccccgag tgatagaagg caaagtagac caggtccggt ctagagtgga
     2101 gcgcaatgcc gtggaagggc tgcgaaccct gtgtgttgca tacaagaggc tcgagccaga
     2161 gcagtacgaa gatgcttgcc gactgctaca gagtgccaaa gtggcgcttc aggaccggga
     2221 gaagaagctg gcagaagcct acgagcagat agagaaggac cttgttctgc ttggtgctac
     2281 ggctgttgag gacaggctcc aggagaaagc tgctgacaca attgaggcac tacagaaggc
     2341 aggcatcaag gtctgggtgc tcaccgggga caagatggag acagcatccg ccacctgcta
     2401 tgcctgcaag ctgttccgca ggagcacgca gctgctggag ctgaccacca agaagctaga
     2461 ggagcagagc ctgcacgatg tgctcttcga cctgagcaag acagtgctgc gctgcagcgg
     2521 gagcatgacc agggactcct tctcggggct ctccacagat atgcacgact atggtttaat
     2581 catcgatgga gcagcactgt ccttgataat gaagccgaga gaggacggga gctcctcggg
     2641 caactaccga gagctcttcc tggagatctg caggaactgc agtgctgtgc tgtgctgccg
     2701 gatggcaccc ttgcagaagg cccagatcgt taagttaatc aaattttcaa aggagcatcc
     2761 tattacctta gcaattggtg atggtgcaaa tgatgtcagt atgatcctgg aggcccacgt
     2821 gggcataggt gtcatcggga aagagggtcg ccaggctgca aggaacagcg actatgcaat
     2881 acccaagttt aaacacttaa agaagatgct tcttgttcat gggcattttt attatatcag
     2941 gatatctgag cttgtgcaat acttctttta taagaacgtc tgcttcattt tccctcagtt
     3001 tttgtaccag ttcttctgcg gattttcaca gcagactttg tacgatactg cgtatctgac
     3061 tctctacaac atcagcttca cttccctccc gattctcctg tacagcctca tggagcagca
     3121 cgtgggcatt gacgtgctca agagagaccc gaccctctac agagacattg ccaagaatgc
     3181 gctgctgcgc tggcgggtgt tcatttactg gacgtttctc ggcgtttttg acgctttggt
     3241 atttttcttt ggtgcttatt tcatatttga gaacacaacc gtgaccatca acggacagat
     3301 gtttgggaac tggaccttcg ggacgctggt gttcactgtg atggtgctca ctgtcacact
     3361 gaagctcgca ctggacacgc actactggac ttggatcaac cactttgtca tctgggggtc
     3421 gctgctcttc tacattgcct tctccctgct ctggggaggg gttatctggc cgttcctcag
     3481 ttaccagagg atgtactatg tgttcatatc catgctgtcc agtgggcctg cctggctggg
     3541 tatcatactg cttgtcacgg tcggcctcct ccctgacgtc ctcaagaagg tcctgtgtag
     3601 gcagctgtgg cccacggcaa cggagagaac tcagcagagc acccgactca aagcattggc
     3661 cgatgccacc tcgaacagcg ccaggcccct gctgaaggac ttcttaccgc agccaagaca
     3721 tgtctagccc aacgctagaa catacaacat caggacagca tttcagaatt cacccctctg
     3781 gcctctttgc cgagctgggg tgctcagggc agcagactct tggctgccca gtgcagctcc
     3841 ccctctggga gagttgtgtg ctccaggtgg gagagcgaag agtgtcctgt gctccctctc
     3901 cacccaggcc ttcctcacaa ggcaaggtat gggtgctgta ggtccagcct ggagatgccc
     3961 acttgatgga cagacagccc cagtgcccca gccgctgaga gctctgttct tgggtacctg
     4021 tgtgtgcctg cacctgtccc acccttcatt ctcagggagg gcggggtgga atcacaggtc
     4081 acccactcag gcacagcaca ctgcaatctg gatggtgcgt ggccggcgtc attgtcccag
     4141 gcctggtgac catacatcca gttgggctct ggaaaaggac attaagcctg gcctcatctt
     4201 aagcactgtg gcttgaagct ggccttgccc ctgagtatcc acccagctgc cgttgtcacc
     4261 tctgctgtct cttgagaaga agatcctatc cctttgtctg cagcctcgtg cgtagcccat
     4321 ggcgcttggc tcatactgta tccggatgtt cctgcccgcc tgcccgagtg tttcctgtgt
     4381 gaaccacaca cacttaccct gtcagacacg gagtggtgtg tgtctcctgg acctgtggcc
     4441 gcgctgtgct catgtttgct gtcccctcac aaagccatct tcctagatca tgtctgagtc
     4501 aatttgctga gatcctgacc ctacacgtcg gagtgtccat gtcagcgtcc ccgtcctgtt
     4561 cccagctgcc tgtggaagat gacgtttatg tatgcgaata agtcacactg ttaaccaagt
     4621 ctctcaggag tgtagtgata gctgccacac tctggaatga tgtcagttaa acatattgga
     4681 aaacatttgt ttcaggggtg cagggaaagg gggaggtttg gggagcccag gcaggtgttt
     4741 tacctcaccc agaggtgagt cccaataccc acgctgtctg gggctactgt ggattcatcc
     4801 gctctagtct gctgctctgg tgcctcctac tggtgccaca cagatcctat ccagggcttc
     4861 acttggaatg gacaggccat cagaaggcca ctggactgtg actctccgct gctgccacac
     4921 tggcatttct gttttcagca acactcccga cagcaccgta atgggcctga ctcagaagac
     4981 ggttttttag tatgatgcag cctttcagaa agaaccaggc agagcctggg ggaaagccag
     5041 ccccaaccct gtggagttgc gtagtgggcc tggagccatg gtgagggtct ctggcacttg
     5101 agagcctata tcctgggaag cacaaatttt ataacatgat tacacaagat ttccctataa
     5161 accgtgtgct tgaactgggg accagccaac agtaggagca acctggcagt tgggggaggt
     5221 tgggtgaaca taaacaccac accaaagatg gggagggggt ggccttgagc ttggaacaga
     5281 caggggatgt ccagctctgc tgagggctgt ctgtgcctcc acacaccctc atgcccattc
     5341 acccacctgt gtcgccatgt gtcagaggat tggagcccca atccacactg gcccttaatt
     5401 agtagtgtgt gcatttttac agctcctttt taagaaccca gacaggcaca aatataatac
     5461 ctgtggggag gggcagattc tctctgtgtt tagttaacag attatttgta atgtattttt
     5521 ttagggatct taaaattacc tttgcactaa agtattttca tagctgtttc tatatcttac
     5581 tcatttgttg atgcaccttc tgatttttaa atatgttttt aaagctttca ctttttaagt
     5641 ttaagaattt tggccactta aatgctggtg agcgtttcgg ctgaatgtct cagtgtctgg
     5701 cagcgacctc tctgattctc ctctgtgcct ctctctttct tgatgtttcc agagactgac
     5761 cagctgagat gtgctgaggg cacaccatct cctctgcttg ctttgtcaca gtcctctgtc
     5821 acgtcacggt ttctattttg attttgtttt ttatttccat ccttcagcct taaacaccta
     5881 aacaacatcc ttcctgcagg gcctcgattc tgcagccctc gccgggtgtg gggacactct
     5941 cctgcacccc cacccctacc cagcagctga agtttactta ggaacttccc agattgaatg
     6001 cacactccaa tgtcctttaa aattgtgctt aggaaattac caaatgaagt tgcctgagaa
     6061 tttgaagtag acaagggcac aggtgaaatg cagagacaga gaccaaacac gcgtgcagaa
     6121 ggccgtccga ctcacctcac agtggctgcg tttgctttcc ttaaaacaag gaacttcaac
     6181 tcaaattaag catcttcttt tcttaattca gttgcacaaa tgaacatctg tggcttacta
     6241 cattggccca gattcatggc tccaccacct acaaatagtt catctcctgt atgttccagg
     6301 agccctggct gcatatgtgt tctcttactt tctgttccac acacatgcca tgtacacatg
     6361 cgcgcgcaca cacagacaca tgtgcattct tcaagaccat gtaccagcct gctttctgac
     6421 agccctgtgc agagatgttg ccctctggag catcaggctc cttacacaca cacaggcaca
     6481 cacacaggca cacacactag gaagggcact gggctatgtg agtgcacgct gtgctggact
     6541 gagctctccc ctcccaggga agcatacctc ccagtcagga ctttcccttg ctccctcagt
     6601 ccagcaggca ggacccaggc caaccaaagc tgcatgccat ccaggcgcct gccccctgcc
     6661 acatgccagc tagggaaacc taatgttcct ccatcccagc gatccattcc tgagcacaag
     6721 cagaccaaag gccccacgca ggggaatggc acacccaaag ctggaacagg gtaacttttc
     6781 agtgttccta ctgagcacat ttcccaggat cagcggccga atgtcccgag tgtggcgtca
     6841 tggccaccca ggtcgctgtg catcacccag gtgtctggtg ttctggagga agccccagcc
     6901 tgggtctctg aacccccaag ttcaaggcat atctgcactg actggtactg gactcaccca
     6961 tccatttatt tcatcttaat gtagtttatt ggcaatgcca tagaacacta gccccttgca
     7021 ttctgcattt cttttggaag ttacccattc atgactacaa acaggaaagc gtcacttggt
     7081 gaatgcaatc tttttgtttt aaaacctaga agacgggtga atggaaaggg gagaggttct
     7141 gatactgtgt ctgaacaaag ctttaatgaa gatacgtatg ttggaagtat tatgaaagtg
     7201 tgattctaat tttgcagaaa aaaatgtcta tcaatttata tagctttatt ttttacctta
     7261 tcaagagata gagaatttta atatgcatat attgtctgac ttagaatcat gtgtgtcagc
     7321 attaccactt aaaatgtcca cctactatgt catgtatgag taagagagaa tcaaagatgt
     7381 atctaacatg aatggttatc tgtaactgtc attgtcataa gaactgggat tgatttaagt
     7441 tatcaaatat agtaagtaca ttaaacatgt cattctccaa cactaatgtc ggactgagag
     7501 cccagtaagc tgctttgaaa cttgtaaatt aaaccggatc aaacgtc
//
