LOCUS       NM_001253353            3309 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus atos homolog B (Atosb), transcript variant 1, mRNA.
ACCESSION   NM_001253353
VERSION     NM_001253353.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3309)
  AUTHORS   Werren,E.A., LaForce,G.R., Srivastava,A., Perillo,D.R., Li,S.,
            Johnson,K., Baris,S., Berger,B., Regan,S.L., Pfennig,C.D., de
            Munnik,S., Pfundt,R., Hebbar,M., Jimenez-Heredia,R.,
            Karakoc-Aydiner,E., Ozen,A., Dmytrus,J., Krolo,A., Corning,K.,
            Prijoles,E.J., Louie,R.J., Lebel,R.R., Le,T.L., Amiel,J.,
            Gordon,C.T., Boztug,K., Girisha,K.M., Shukla,A., Bielas,S.L. and
            Schaffer,A.E.
  TITLE     TREX tetramer disruption alters RNA processing necessary for
            corticogenesis in THOC6 Intellectual Disability Syndrome
  JOURNAL   Nat Commun 15 (1), 1640 (2024)
   PUBMED   38388531
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3309)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672276.9, AK149610.1 and BQ175731.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Variants 1, 2 and 3 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK149610.1, SRR14777534.1005321.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AL672276.9         176367-176509       c
            144-1527            AK149610.1         2-1385
            1528-1528           AL672276.9         170953-170953       c
            1529-3063           AK149610.1         1387-2921
            3064-3309           BQ175731.1         1-246               c
FEATURES             Location/Qualifiers
     source          1..3309
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 22.99 cM"
     gene            1..3309
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /note="atos homolog B"
                     /db_xref="GeneID:230088"
                     /db_xref="MGI:MGI:2441854"
     exon            1..336
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     exon            337..480
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     exon            481..1449
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     CDS             556..2172
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /note="protein FAM214B; family with sequence similarity
                     214, member B"
                     /codon_start=1
                     /product="atos homolog protein B"
                     /protein_id="NP_001240282.1"
                     /db_xref="CCDS:CCDS18090.1"
                     /db_xref="GeneID:230088"
                     /db_xref="MGI:MGI:2441854"
                     /translation="MRHVQAELSPSSEPEAGPSQPPVRQGTLQGGLLMGYSPAGGATS
                     PGVYQVSIFSPSAGASEPPRALKRPAPPTEGPRELKRGPGLGAREGLPPEEPSTVGLL
                     SPEGLGLGLGVASQHFSHHGLCVVEHGGNTTSPWTSGTQSTPWLSSNASFNTLHTRDW
                     AFPDQGGQGCLGETPGPAPSGQLHTLDTDLHNLAQIGGKSPVARVGNGSNPWPRESHG
                     TANGHSPEHTPPGPGPPGPCPTKRRLLPAGETLDVSSEDEGPAPRRRRGTLGCPLAAN
                     SSDAKATPFWSHLLPGPKEPVLDPTDCSPMGRRLKGARRLKLSSLRTLRKGPGLLSPP
                     SASPFPTPAVSRTLLGNFEESLLRGRFAPSGHIEGFTAEIGASGSYCPQHVTLPVTVT
                     FFDVSEQNAPAPFLGVVDLTPLGRKGYSVPKVGTIQVTLFNPNQTVVKMFLVTFDFSD
                     MPAAHMTFLRHRLFLVPVGEEGNASPTHRLLCYLLHLRFRSSRSGRLSLHGDIRLLFS
                     RRSLELDTGLPYELQAVTEAPHNPRYSPLP"
     exon            1450..1508
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1614
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1773
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..1842
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     exon            1843..2018
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     exon            2019..3293
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2273..2278
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /note="hexamer: ATTAAA"
     polyA_site      2302
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
     regulatory      3268..3273
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /note="hexamer: AATAAA"
     polyA_site      3293
                     /gene="Atosb"
                     /gene_synonym="B230312A22Rik; Fam214b"
                     /note="major polyA site"
ORIGIN      
        1 ggccccatca gctggtagga aatggcctgt gagtcagagg ggcagctgag tctgcggcgc
       61 ggagccgggg cggccccggg gagggaccgt cgcagggagg ggtgcaacag cagctagagg
      121 ggctgcggac gccagagccc gctagtgttg cacacgaagc tgatcaggga agggccaagc
      181 agagcaaggc tctcagccta agccaccctt tgtctgggtt gggggcccgt agtagggggg
      241 actggttatc cgaggggagg gaccgggacg gggacgggac cgggacggaa gggcccggag
      301 cagcggccac cgcggcggag ccaatttggg agcgggggtc caactgagcc cagaagctgc
      361 acggaatggt ggcagccacc ttgccggtgc agtgggcatg gaccagactg caagctagag
      421 ggacaagaca tcagacagga agagaggaca cgcgcccagg cttgaggctt cttcatcggg
      481 atgtccccag gccccccagc ccaggcccag cataaaggcc gtgtgggggg gcccccctga
      541 cccaaggggg gcttcatgcg ccacgtgcag gcggagctgt ctccatcctc agagccagag
      601 gctggccctt cacagcctcc agtcagacag gggaccctcc agggtggcct gctcatgggc
      661 tacagcccag cagggggggc gacatccccc ggggtctacc aggtatccat cttttcccct
      721 tcagctggtg cctccgagcc tcctagggct ctgaagcggc cggcccctcc caccgagggt
      781 ccccgggagc tgaagagagg ccctgggctg ggggccagag agggactacc ccctgaagaa
      841 ccatctactg tgggactctt gagcccagag ggactgggtc tgggactggg tgtggctagc
      901 cagcatttct cccaccatgg cctctgtgtt gtggagcacg gaggtaatac cacctcacct
      961 tggacttcag ggacccagag tacaccctgg ctctcatcaa atgcttcctt caatactttg
     1021 cacaccagag actgggcttt cccagatcaa gggggacagg ggtgcctggg ggagactcca
     1081 gggccagccc cttcaggcca gctgcacaca cttgacactg atttgcacaa tcttgcacaa
     1141 atagggggta agagcccagt ggctagggtg ggcaacggga gcaacccctg gcctagggag
     1201 tcccatggaa ctgccaatgg gcacagtccc gagcacacac cccctggccc tggacctcct
     1261 ggcccctgcc ccaccaagcg aaggctgctg cctgctggag aaacccttga tgtcagctct
     1321 gaggatgagg ggccagcccc tcggaggcgc cggggaaccc tgggctgccc tcttgctgcc
     1381 aatagttctg atgccaaagc cacacccttc tggagccacc tgctgcctgg gcccaaggag
     1441 cctgttttgg acccaacaga ctgcagtccc atggggcgga ggctgaaagg cgcccgtcgc
     1501 ctgaagctaa gctcccttcg aactctccgg aaggggccag gcctgctgag ccctcccagt
     1561 gcctccccct ttcccacccc tgctgtcagc cggaccctgc tgggcaactt tgaggaatca
     1621 ctgcttcgag gacgctttgc accatctggc cacattgagg gctttactgc agagattgga
     1681 gccagtgggt cttactgtcc ccaacatgtc acgctgcccg tcactgtcac cttttttgat
     1741 gtttctgagc aaaatgcgcc ggcccccttc ctgggagtcg tggacctgac tcctctgggg
     1801 aggaagggtt acagtgtgcc caaggtgggc accatccaag tgaccttatt taaccccaac
     1861 cagactgtgg tgaagatgtt ccttgtgacc tttgacttct cggacatgcc tgctgcccac
     1921 atgaccttcc tgcgccatcg cctcttcttg gtgcctgtgg gtgaggaggg aaatgctagc
     1981 cccacccacc gcctcctctg ctacttgctg cacctcaggt tccggagctc tcgctcaggc
     2041 cgcttaagcc tgcatggaga tatccgcctg cttttttccc gccggagcct ggagctggac
     2101 acggggctcc cctatgaact tcaggctgtg actgaggccc cccataatcc acgttattca
     2161 cctttgccct gatcgcaagc atcctgaacc taggtgggcc caaagcctgc ctgtcctacc
     2221 atcctggaca gggtaaactg tggagaaatg gcgagagccc cttcaggctt gaattaaagt
     2281 cctcatcccg ctcacgccca aattgactat ttgggtgttt aaagcttcgg tccttccata
     2341 ccctgtctgc tctgggtact tcatgtgcct gtcccctccc ttgggtttcc caggccagct
     2401 taggtagtta gggaggaacc agagctaccc tgagattgtc ccaagttccc aggcaagtaa
     2461 tgccagcgtt gcctccctgt cctgggcagg ggccacttat tattttattt atttttaatt
     2521 tataatttat tcaaattgga ttgccttggt gacctcccaa acctgataat tggcatcacc
     2581 ccactctcag atattgctcc aacctcagga cttgaagaag ctgatgtcgg ggcaagggga
     2641 gagctgctct cctctggcta agggcagagg gtttattcca gaggaactga gtcacttagc
     2701 caaagactca gcttccctcg gctttctcta ttccttttcc ctttcctgcc cttcaaccca
     2761 tcttcgaaag cctgtatgtg tggtgtgtgt gtgtgtgtgt gtgtgtgtgt gtacagctgt
     2821 gtgcgtgcat acaaacttgg gtttgtgtag ggtgtgtgtg tgagagagag acagaatgtg
     2881 catgtatgtg taacacaggg gtttagccac ctcttaccta gggctcagac tcacttgtcc
     2941 ctctcctcct gcctgtgtct ccttgctttg gtgtcctgac tgaggaaggt gtccagggac
     3001 agagtcaggc ctaaggactg gggaacctcc tctcacctga ccagactctg acccacctac
     3061 ctcagctggg atgaggggtg cccctcattc agtcacatgg ttcccagtta ctccactcct
     3121 cacttaagac tctgacccag cctcaaccct taactcttgg ggcttggctg aggggaacaa
     3181 gcatttgctg aaacttgaaa aacaaaacaa acaaacaaaa aaatgggaaa aattgtacct
     3241 ggtacatttt ttaaggaaaa aaaaaagaat aaattcttgt ttggaaactt gaaaaaaaaa
     3301 aaaaaaaaa
//
