LOCUS       NM_001364648            1297 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus atonal bHLH transcription factor 7 (Atoh7), transcript
            variant 2, mRNA.
ACCESSION   NM_001364648 XM_006513889
VERSION     NM_001364648.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Stebbins,K., Somaiya,R.D., Sabbagh,U., Khaksar,P., Liang,Y., Su,J.
            and Fox,M.A.
  TITLE     Retinal Input Is Required for the Maintenance of Neuronal Laminae
            in the Ventrolateral Geniculate Nucleus
  JOURNAL   eNeuro 11 (9) (2024)
   PUBMED   39160068
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  AUTHORS   Kozlowski,C., Hadyniak,S.E. and Kay,J.N.
  TITLE     Retinal neurons establish mosaic patterning by excluding homotypic
            somata from their dendritic territories
  JOURNAL   Cell Rep 43 (8), 114615 (2024)
   PUBMED   39133615
REFERENCE   3  (bases 1 to 1297)
  AUTHORS   Fischl,M., Pederson,A., Voglewede,R., Cheng,H., Drew,J., Torres
            Cadenas,L. and Weisz,C.J.C.
  TITLE     Fast Inhibition Slows and Desynchronizes Mouse Auditory Efferent
            Neuron Activity
  JOURNAL   J Neurosci 44 (33), e0382242024 (2024)
   PUBMED   38937103
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1297)
  AUTHORS   Schott,M., Leon-Perinan,D., Splendiani,E., Strenger,L., Licha,J.R.,
            Pentimalli,T.M., Schallenberg,S., Alles,J., Samut Tagliaferro,S.,
            Boltengagen,A., Ehrig,S., Abbiati,S., Dommerich,S., Pagani,M.,
            Ferretti,E., Macino,G., Karaiskos,N. and Rajewsky,N.
  TITLE     Open-ST: High-resolution spatial transcriptomics in 3D
  JOURNAL   Cell 187 (15), 3953-3972 (2024)
   PUBMED   38917789
REFERENCE   5  (bases 1 to 1297)
  AUTHORS   Campbell,P.W., Govindaiah,G. and Guido,W.
  TITLE     Development of reciprocal connections between the dorsal lateral
            geniculate nucleus and the thalamic reticular nucleus
  JOURNAL   Neural Dev 19 (1), 6 (2024)
   PUBMED   38890758
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1297)
  AUTHORS   Zhao,S., Hung,F.C., Colvin,J.S., White,A., Dai,W., Lovicu,F.J.,
            Ornitz,D.M. and Overbeek,P.A.
  TITLE     Patterning the optic neuroepithelium by FGF signaling and Ras
            activation
  JOURNAL   Development 128 (24), 5051-5060 (2001)
   PUBMED   11748141
REFERENCE   7  (bases 1 to 1297)
  AUTHORS   Lee,C.S., May,N.R. and Fan,C.M.
  TITLE     Transdifferentiation of the ventral retinal pigmented epithelium to
            neural retina in the growth arrest specific gene 1 mutant
  JOURNAL   Dev Biol 236 (1), 17-29 (2001)
   PUBMED   11456441
REFERENCE   8  (bases 1 to 1297)
  AUTHORS   Brown,N.L., Patel,S., Brzezinski,J. and Glaser,T.
  TITLE     Math5 is required for retinal ganglion cell and optic nerve
            formation
  JOURNAL   Development 128 (13), 2497-2508 (2001)
   PUBMED   11493566
REFERENCE   9  (bases 1 to 1297)
  AUTHORS   Wang,S.W., Kim,B.S., Ding,K., Wang,H., Sun,D., Johnson,R.L.,
            Klein,W.H. and Gan,L.
  TITLE     Requirement for math5 in the development of retinal ganglion cells
  JOURNAL   Genes Dev 15 (1), 24-29 (2001)
   PUBMED   11156601
REFERENCE   10 (bases 1 to 1297)
  AUTHORS   Brown,N.L., Kanekar,S., Vetter,M.L., Tucker,P.K., Gemza,D.L. and
            Glaser,T.
  TITLE     Math5 encodes a murine basic helix-loop-helix transcription factor
            expressed during early stages of retinal neurogenesis
  JOURNAL   Development 125 (23), 4821-4833 (1998)
   PUBMED   9806930
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155909.9.
            
            On Jun 20, 2019 this sequence version replaced NM_001364648.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY705389.1, AK005214.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-752               AC155909.9         158087-158838       c
            753-1297            AC155909.9         157343-157887       c
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 32.54 cM"
     gene            1..1297
                     /gene="Atoh7"
                     /gene_synonym="bHLHa13; Math5"
                     /note="atonal bHLH transcription factor 7"
                     /db_xref="GeneID:53404"
                     /db_xref="MGI:MGI:1355553"
     exon            1..752
                     /gene="Atoh7"
                     /gene_synonym="bHLHa13; Math5"
                     /inference="alignment:Splign:2.1.0"
     CDS             372..761
                     /gene="Atoh7"
                     /gene_synonym="bHLHa13; Math5"
                     /note="isoform 2 is encoded by transcript variant 2;
                     protein atonal homolog 7; helix-loop-helix protein mATH-5;
                     transcription factor Atoh7"
                     /codon_start=1
                     /product="transcription factor Atoh7 isoform 2"
                     /protein_id="NP_001351577.1"
                     /db_xref="GeneID:53404"
                     /db_xref="MGI:MGI:1355553"
                     /translation="MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRL
                     AANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAER
                     DWVGLRCEQRGRDHPYLPFPGARLQVS"
     exon            753..1297
                     /gene="Atoh7"
                     /gene_synonym="bHLHa13; Math5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1278..1283
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atoh7"
                     /gene_synonym="bHLHa13; Math5"
                     /note="hexamer: AATATA"
     polyA_site      1297
                     /gene="Atoh7"
                     /gene_synonym="bHLHa13; Math5"
                     /note="major polyA site"
ORIGIN      
        1 gacatctact gcaagctgtc caaacgctcc tgacctagca gagcttctgg gaagatttcg
       61 tcaccccgaa aagcagtctc aggctttccc agagaactgg aaaggctttc tatccccgac
      121 ccccaagaac gatccgcagc aaactgcaag aaagtttcct cctcgttcaa ctttacgtgt
      181 ttggggtgga gtggggagga atgacttttt cctgagcatc acttccactg catctgggca
      241 agggaaggga cttcccagca ggacccaagc tagggtccca cacagtgtcc tctggccact
      301 gactgactgc acgtgagtcg ctccgtctgt gtcttattca ctcttgggag tcctgcagag
      361 cggcagcgtg gatgaagtcg gcctgcaaac cccacggccc tccggcggga gctcgcggcg
      421 cgcccccgtg cgcgggcgca gccgagcgcg cggtctcgtg cgcggggccc gggcggctgg
      481 agagcgcggc gcgcaggcgt ctggcggcca acgcgcgcga gcggcgccgc atgcaggggc
      541 tgaacacggc gttcgaccgg ctgcgcaggg tggtgccgca gtggggccag gacaagaagc
      601 tgtccaagta cgagacactg cagatggcgc tcagctacat catcgcgctc acccgcatcc
      661 tagccgaagc cgagcgggac tgggtcgggc tgcgctgcga gcagcggggc cgcgatcacc
      721 cctacctccc tttcccgggt gctaggctcc aggtttcatg agtggacatc gcgaatgact
      781 ttggactgct gtgaaaataa tgctctgttc cttttagcct aagacaacgg ggctggggtc
      841 tagccgagtt tgtagaggac ttgtcttgca tgtataaaag tggggttgag ccccagctgc
      901 cgcttaggca gagcacggtg atgcacggcc tgtaatccta gcgtcattca ggaggtggag
      961 aaacatatat atttaaatat ttaagacccc atgtcaaaaa aaaaaaaaag attgaataag
     1021 actggtacta aaccatcaga cagttagtta ccttcttaaa ctgtgcaagt ttgtccctat
     1081 tgggcgaagt tgtattatgt gacttgttta tgttctgagc agctaccttg tggtgtaaat
     1141 gcatttatgc tccgtatatt gtgtgtgcat gcatcagata gagtaagact tttttttccc
     1201 ccctggggtc gagggttggg gagctggtag agtacttggg tatgagcgct ctgtattttt
     1261 ttaactgtac acattaaaat atagattttg taaaata
//
