LOCUS       NM_001403515           10230 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus autophagy related 2B (Atg2b), transcript variant 2,
            mRNA.
ACCESSION   NM_001403515 XM_006516360
VERSION     NM_001403515.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 10230)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 10230)
  AUTHORS   Sakai,S.S., Hasegawa,A., Ishimura,R., Tamura,N., Kageyama,S.,
            Komatsu-Hirota,S., Abe,M., Ling,Y., Okuda,S., Funayama,M.,
            Kikkawa,M., Miura,Y., Sakimura,K., Narita,I., Waguri,S., Shimizu,R.
            and Komatsu,M.
  TITLE     Loss of Atg2b and Gskip Impairs the Maintenance of the
            Hematopoietic Stem Cell Pool Size
  JOURNAL   Mol Cell Biol 42 (1), e0002421 (2022)
   PUBMED   34748402
REFERENCE   3  (bases 1 to 10230)
  AUTHORS   Yang,F., Lei,Y., Zhou,M., Yao,Q., Han,Y., Wu,X., Zhong,W., Zhu,C.,
            Xu,W., Tao,R., Chen,X., Lin,D., Rahman,K., Tyagi,R., Habib,Z.,
            Xiao,S., Wang,D., Yu,Y., Chen,H., Fu,Z. and Cao,G.
  TITLE     Development and application of a recombination-based library versus
            library high- throughput yeast two-hybrid (RLL-Y2H) screening
            system
  JOURNAL   Nucleic Acids Res 46 (3), e17 (2018)
   PUBMED   29165646
REFERENCE   4  (bases 1 to 10230)
  AUTHORS   Nicola,A.M., Albuquerque,P., Martinez,L.R., Dal-Rosso,R.A.,
            Saylor,C., De Jesus,M., Nosanchuk,J.D. and Casadevall,A.
  TITLE     Macrophage autophagy in immunity to Cryptococcus neoformans and
            Candida albicans
  JOURNAL   Infect Immun 80 (9), 3065-3076 (2012)
   PUBMED   22710871
REFERENCE   5  (bases 1 to 10230)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 10230)
  AUTHORS   Gaubatz,J.W. and Cutler,R.G.
  TITLE     Mouse satellite DNA is transcribed in senescent cardiac muscle
  JOURNAL   J Biol Chem 265 (29), 17753-17758 (1990)
   PUBMED   1698780
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158526.3 and AC068459.9.
            
            On Mar 31, 2022 this sequence version replaced XM_006516360.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.15655.1,
                                           SRR10223969.12197.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-627               AC158526.3         151541-152167
            628-790             AC158526.3         161823-161985
            791-943             AC158526.3         165208-165360
            944-1046            AC158526.3         166059-166161
            1047-1209           AC158526.3         167410-167572
            1210-1389           AC158526.3         170060-170239
            1390-1486           AC158526.3         172096-172192
            1487-1672           AC158526.3         172727-172912
            1673-1827           AC158526.3         173875-174029
            1828-1930           AC158526.3         174119-174221
            1931-2192           AC158526.3         175575-175836
            2193-2343           AC158526.3         177848-177998
            2344-2436           AC068459.9         197979-198071       c
            2437-2625           AC068459.9         197678-197866       c
            2626-2899           AC068459.9         193720-193993       c
            2900-3002           AC068459.9         192240-192342       c
            3003-3198           AC068459.9         191770-191965       c
            3199-3341           AC068459.9         191092-191234       c
            3342-3499           AC068459.9         189186-189343       c
            3500-3672           AC068459.9         188700-188872       c
            3673-3823           AC068459.9         188024-188174       c
            3824-4023           AC068459.9         186464-186663       c
            4024-4104           AC068459.9         186235-186315       c
            4105-4211           AC068459.9         185083-185189       c
            4212-4304           AC068459.9         184543-184635       c
            4305-4375           AC068459.9         184004-184074       c
            4376-4452           AC068459.9         183504-183580       c
            4453-4623           AC068459.9         182901-183071       c
            4624-4765           AC068459.9         180863-181004       c
            4766-4968           AC068459.9         178913-179115       c
            4969-5195           AC068459.9         177622-177848       c
            5196-5304           AC068459.9         176158-176266       c
            5305-5499           AC068459.9         175396-175590       c
            5500-5601           AC068459.9         174631-174732       c
            5602-5680           AC068459.9         166439-166517       c
            5681-5885           AC068459.9         165889-166093       c
            5886-5955           AC068459.9         163626-163695       c
            5956-6038           AC068459.9         163132-163214       c
            6039-6160           AC068459.9         162418-162539       c
            6161-6315           AC068459.9         161814-161968       c
            6316-6465           AC068459.9         160918-161067       c
            6466-10230          AC068459.9         153250-157014       c
FEATURES             Location/Qualifiers
     source          1..10230
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 55.82 cM"
     gene            1..10230
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /note="autophagy related 2B"
                     /db_xref="GeneID:76559"
                     /db_xref="MGI:MGI:1923809"
     exon            1..627
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     CDS             466..6696
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /note="isoform 2 is encoded by transcript variant 2;
                     autophagy-related protein 2 homolog B; ATG2 autophagy
                     related 2 homolog B"
                     /codon_start=1
                     /product="autophagy-related protein 2 homolog B isoform 2"
                     /protein_id="NP_001390444.1"
                     /db_xref="GeneID:76559"
                     /db_xref="MGI:MGI:1923809"
                     /translation="MPWPFSESIKKRACRYLLQRYLGHFLQEKLSLEQLSLDLYQGTG
                     SLAQVPLDKWCLNEILESADAPLEVTEGFIQSISLSVPWGSLLQDNCALEVRGLEMVF
                     RPRPRVATGSEPMYWSSFMTSSMQLAKECLSQKLTDEQGEASQPFEGLEKFAETIETV
                     LRRVKVTFIDTVLRIEHVPENSKTGAALEIRVDRTVYCDETADESSGVNVHQPTAFAH
                     KLLQLSGVSLFWDEFSASAKSSPVCSTAPVETEPKLSPSWNPKIVYEPHPQLTRTLPE
                     IAPSDPVQIGRLLGRLELSLTLKQNEVLPGAKLDVDGQIDSFHLFLSPRQVHLLLDML
                     AAIAGPENSSKIGLANKDRKNRPMQQEDEYRIQMELNRYYLRKDSLSMGVSSEKSFYE
                     TETARTPSSREEEVFFSMADMDMSHSLSSLPPLGDPPHMDLELSLTSTYTNTPAGSPL
                     SATVLQPTWGEFADHKEQPVRGPAFQSDVVHPASLQKAALSSRSASVDESRPEFICRL
                     ALGIFSVSVLHIDPLSPAETSLNVNPLTRMATDFFSCVEKMDPAIFSTGDFKSFRAVF
                     AEACSHDHLRFIGTGIKVSYEQRQRSASRHFSTDMSVGQMEFLECLFPTDCHSVPSHY
                     TELLTFHSKEGTDAHLPVCLQLHYKHSETRGPQGNQARLSSVPQKAELQIKLNPVCCE
                     LDISIVDRLNSLLQPQKLTTVEMMASHMYASYNKHISLHKAFTEVFLDDSHSPANRRV
                     SVQVATPALHLSVRFPIPDLRSDQERGPWFKKSLQKETLHLEFTDLESKTEFVGGSTP
                     EQTKLELTFRELSGSFQEEKGGPSVKFFHVSGGVDGDTASSDDFDWPRMVLKINPPAM
                     HSILERIAAEEEEENDGHYQEEEDGGAHSLKDVCDLRRPAPSPFSSRRVMFENEQMVM
                     PGDPVEMTEFQDKAISNSHYVLELLLPNIHLTLPNKGFYEKLYNRIFNDLLLWEPTAP
                     SPVETLENVSYGIGLSVASQLINTFSKDSFSPFKSAVHYDEDSGSEEETLQYFSAVDP
                     NYRSRRKKKLDSQNKNSQSFLSVLLSINHGLMAVFTDVKQENGDPMESKHGEFWLEFN
                     SGSFFCVTKYEGFEDKHYICLHSSSLRLYHKGIVDGAILPTETRLPCSTRPHWLEPTI
                     YSSEEDGLSRTASDGVGGDNLNMLSVAVKILSDKSESNTKEFLVAVGLKGATLQHRVL
                     PAGLSWHEQILNFLNIADEPVLGYNPPTSFTTFHVHLWSCALDYRPLHLPLRSLLTVE
                     TFSISSSVALDKSSSTLRIIMDEAALHLSDKCNTVTVNLNRDYVRVMDMGLLELTITA
                     VKSDSDGEQTAPRFELHCSSDVVHIRTCSDSCAALMNLIQYVASYGDLHGPHKAEMKP
                     GVPQRKPKVDSSARSSSHGPVLPEADQQILRDLMSDAMEEIDLQQASAPVGPQANGVL
                     DEKSHTQEPCCSDLFLFPDESGNVSQESSPAYPSLTHHLISDAVTGVTAENDDFCILF
                     APKTVVQEKEEEPVIKIMVDDAIVIKDDYFSLPITRTDSSKAPLHFPIPAVRYVVKEV
                     SLVWHLYGGKDFATAPPTSPAKSYISPHSSPSQTPTRHGRHTVCGGKGRNHDFLMEIQ
                     LSKVKFQHEVYPPCKPECESSLLEHPVSRQVFIVQDLEIRDRLATSQMNKFLYLYCSK
                     DMPRKAHSNMLTIKALHVRPESGRSPQECCLRVSLMPLRLNIDQDALFFLKDFFTSLS
                     TEVELLLTPDPEVTKSPGADVTCSLPRHLSTSKEPNLVVSFPGPKQASPNHRANSAEG
                     GNGLEEDVSAEETSFSDQPVFFREFRFTAEVPIRLDYHGKHVSMDQGTLAGILIGLAQ
                     LNCSELKLKRLFYRHGLLGIDKLFSYAISEWLSDIKKNQLPGILGGVGPMHSLVQLVQ
                     GLKDLVWLPIEQYRKDGRIVRGFQRGAASFGTSTAMAALELTNRMVQTIQAAAETAYD
                     MVSPSTLSIEPKKAKRFPHHRLAHQPVDLREGVAKAYSVVKEGITDTAQTIYETAARE
                     HESRGVTGAVGEVLRQIPPAVVRPLIVATEATSNVLGGMRNQIRPDVRQDESQKWRHG
                     ED"
     exon            628..790
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            791..943
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1046
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1209
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1389
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1486
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1672
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            1673..1827
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            1828..1930
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            1931..2192
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            2193..2343
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            2344..2436
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            2437..2625
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            2626..2899
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            2900..3002
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            3003..3198
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            3199..3341
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            3342..3499
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            3500..3672
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            3673..3823
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            3824..4023
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4024..4104
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4105..4211
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4212..4304
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4305..4375
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4376..4452
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4453..4623
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4624..4765
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4766..4968
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            4969..5195
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            5196..5304
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            5305..5499
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            5500..5601
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            5602..5680
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            5681..5885
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            5886..5955
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            5956..6038
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            6039..6160
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            6161..6315
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            6316..6465
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     exon            6466..10230
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7608..7613
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /note="hexamer: AATAAA"
     polyA_site      7633
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /note="major polyA site"
     regulatory      10198..10203
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
                     /note="hexamer: ATTAAA"
     polyA_site      10230
                     /gene="Atg2b"
                     /gene_synonym="2410024A21Rik; C030004M05Rik;
                     C630028L02Rik; mKIAA4067"
ORIGIN      
        1 gtcacttccg cttgtgcccg ttgctcgagt acgtgccggg agtctgggtc tcgcgaacgc
       61 gccaggagcg tgtctcaggc gggagcgcgc ccagtagatg acaacaaatt agtcgcgccg
      121 cgtcggagtc ttgtctcgcc tcagccgcca gccctctctg tctgtccctc tgtctcccta
      181 ccgacggagc gcttcggaag ctcccggctt ggggcgcccg gttctgctca gcgcccagtc
      241 cccgccgggc ctagtgcgag cgtcgcgacg cgggccatgg ggttgccctg agggacggcg
      301 gcgccgaacc gacatgcagc ggccaccgcg aacctagatc cccaccgcgg cttggggacg
      361 ccgccgggcc gaccctgagg cgctgccgct gcctggagcc caggtcggat cccccgagtc
      421 gccgccgcgt gcagccccgg ctccctcgag ccgccagccc tcaccatgcc ttggccattt
      481 tcagaatcca tcaagaagag ggcctgtcgc tacctcctac agaggtacct gggccacttc
      541 ctgcaggaga agctgagcct ggagcagctg agcctggatc tgtaccaggg caccgggtcc
      601 cttgcccagg tccccttgga caaatggtgt ctcaatgaaa tcctggagtc agcagatgca
      661 ccattagaag tcactgaagg atttattcag tccatttccc tgtccgtccc atggggctcc
      721 ttgctgcagg acaactgtgc cctggaagtg agaggactgg agatggtctt ccggcctcga
      781 cctcgagtag caactgggtc cgagcctatg tactggtcaa gcttcatgac cagcagtatg
      841 cagctggcaa aggagtgcct tagccagaaa ctgacagatg agcaaggaga ggcatcccaa
      901 cctttcgagg gactggaaaa gtttgcagaa accatcgaaa cagtactaag aagagtgaaa
      961 gtcactttta tagatactgt tttaagaatt gaacatgtgc cagaaaattc taaaactgga
     1021 gctgcacttg aaatccgagt agacaggacc gtgtactgtg acgaaacagc cgacgagtcc
     1081 tcaggagtca atgtgcatca gcccacagct tttgctcata aattgctgca gctctctggg
     1141 gtgtctctgt tctgggatga gttttctgct tcagcaaaat cttcccccgt gtgttcaact
     1201 gcaccagtgg aaactgagcc aaagctgtca cctagctgga accccaaaat tgtttatgag
     1261 ccacacccac aactaactag aacgttaccg gagatcgcac cctcggatcc agtgcagatt
     1321 ggaaggctac tgggcaggct ggagttgagt ctcactttaa aacagaatga agtgcttcca
     1381 ggagccaagt tggatgtcga tggacagata gactcctttc atctattcct gtcaccgagg
     1441 caggtacacc tccttctgga tatgttagca gctattgctg gaccagaaaa ttctagcaaa
     1501 atagggctgg ctaataaaga caggaaaaat cgacccatgc agcaggaaga tgagtacaga
     1561 attcagatgg aattaaaccg gtattatctg aggaaagatt ccctctctat gggtgtgtct
     1621 tctgagaaga gcttctatga gacagaaaca gctcgtacac cttctagccg tgaggaagaa
     1681 gttttcttct ccatggccga catggacatg tctcacagtc tgtcctctct tccacccctt
     1741 ggggacccac cacacatgga cctggagctg tcgctgacga gtacatacac caacacaccc
     1801 gcagggtccc cgctaagcgc cactgtgctt cagccaactt ggggagagtt tgccgaccac
     1861 aaagaacagc cagtcagagg gccagcattc cagtctgacg tggtgcaccc ggcatcttta
     1921 caaaaagctg ctctctcctc taggtctgct tcagtggatg aatccagacc tgagtttatc
     1981 tgcaggctgg ctctcggcat attctccgtc tccgtgcttc acatcgatcc tttgtctcca
     2041 gcggaaacgt ctctgaacgt caacccattg acacgcatgg ccaccgattt cttctcctgt
     2101 gtagaaaaga tggacccagc aatattttcg acgggagact ttaagtcttt ccgagcagtc
     2161 tttgccgaag cttgttcaca cgatcacctt aggtttatag gtactggcat caaagtgtcc
     2221 tatgagcaga gacaaaggtc agcttcccgg cactttagca ccgacatgtc cgttgggcaa
     2281 atggagtttt tggagtgtct gtttccaaca gattgtcatt ctgtcccttc tcactacacc
     2341 gagcttctaa cgttccattc caaagaaggg acggatgccc accttcccgt ttgtcttcag
     2401 cttcactata aacactcaga gactagagga ccccagggta atcaagcaag acttagttca
     2461 gttcctcaaa aggcagaatt acaaattaaa ttaaaccccg tgtgttgcga gctggatatc
     2521 agtattgtgg ataggttaaa ttccttgctt caacctcaga aactcactac cgtggagatg
     2581 atggcctcgc acatgtatgc gtcctataac aagcatatta gtttgcacaa ggctttcacg
     2641 gaagtgttcc tagatgactc acacagtcct gcaaaccgtc gggtgtccgt acaagttgcc
     2701 accccagccc tgcacctgtc tgttcgcttc cctattcctg atctaagatc agaccaggaa
     2761 agaggaccct ggtttaagaa gtcacttcag aaggagaccc ttcatttaga atttacggat
     2821 ctggagtcca agacagagtt cgtgggagga tccaccccag aacaaactaa actggagctg
     2881 acttttcgag agctatctgg gtcgttccag gaggagaagg gagggccatc tgtcaagttc
     2941 ttccatgtgt ctggtggagt agatggagac accgcatcgt cagatgactt tgactggcca
     3001 cgaatggtac tgaaaataaa cccaccagcc atgcattcca ttttggagag aatagcagcc
     3061 gaggaagagg aagagaatga tggtcactac caggaggagg aggacggagg ggctcattcc
     3121 ctgaaagatg tctgtgacct gaggcggcca gccccgtctc ccttttcctc tcgtcgagtg
     3181 atgtttgaga atgagcagat ggtgatgccg ggagaccctg tggagatgac ggagtttcag
     3241 gataaagcca tcagcaactc gcactacgtg ctggagctcc tgttgcccaa catccacctg
     3301 acgctgccca acaaaggctt ctacgagaag ctctataaca ggatctttaa cgacttgctt
     3361 ctctgggagc caacagcgcc ttcaccagtg gagacacttg aaaacgtttc ctatggcatc
     3421 ggactctccg tggccagtca gctgatcaat accttcagca aagatagctt cagtcccttt
     3481 aaatctgcag ttcactatga tgaagacagt ggatctgaag aagagacttt gcagtatttt
     3541 tctgctgttg atcccaacta tcgttcccgt aggaaaaaaa agttggactc tcagaacaag
     3601 aactctcaga gcttcctctc agtgcttctg agtatcaatc atggactaat ggcagtgttc
     3661 actgatgtga agcaagagaa tggagatccg atggaaagta agcatggtga attctggcta
     3721 gaattcaata gcggctcgtt cttctgcgtg acaaagtatg agggctttga ggacaagcac
     3781 tacatctgct tgcattccag cagcctcagg ctgtaccaca aaggcatagt agatggagcc
     3841 attctcccta cagagacgcg cttgccctgt tccacccgcc cacactggct ggaacctaca
     3901 atttattcct ctgaagaaga tggcctcagc cgcactgcct cagatggggt tgggggagac
     3961 aatttgaata tgctctcagt cgcagtgaag atactgtctg ataagtccga gtccaacacg
     4021 aaggagttcc tcgtggctgt ggggctgaaa ggagccactc tacagcacag ggtgctgccc
     4081 gctggactca gttggcacga gcagatttta aacttcttga atattgctga tgaacctgtt
     4141 ttgggatata accctccaac ttcatttaca actttccatg tccatctttg gagctgtgca
     4201 cttgattaca ggccccttca cctgccactc cgatcccttc ttactgttga gacgttcagc
     4261 atttctagca gtgttgcttt ggataaatct tcctccactc tcagaatcat catggacgag
     4321 gctgctttgc acctgtcaga caagtgcaac acggtcactg taaacctgaa tagagattat
     4381 gttcgtgtga tggacatggg acttttagag ctgaccataa ccgcagtaaa atctgattct
     4441 gatggagaac agactgcgcc ccgctttgag ttacactgtt ccagtgacgt cgtgcacatc
     4501 agaacatgct cagactcatg tgctgcgctg atgaacctca ttcagtatgt cgcaagttac
     4561 ggggacctac atggacctca caaagcagag atgaagcctg gagtcccaca gagaaagccc
     4621 aaggtagatt ccagcgctcg gtcatcttca catggtccag tgcttcctga agcagatcag
     4681 cagattttac gggacctgat gagtgatgcc atggaggaga ttgatctgca gcaggcctct
     4741 gcccctgtcg gaccacaggc taatggtgtc ctggatgaaa agtctcacac tcaggagccg
     4801 tgctgttcag acctcttcct gttcccagat gagagtggaa atgtgtccca ggagtccagc
     4861 cctgcctatc cgtctctcac tcaccacttg atcagtgacg cggtgaccgg tgtgaccgct
     4921 gaaaatgatg acttctgtat tctttttgca ccaaaaacag tcgttcagga gaaggaagaa
     4981 gagccagtga taaagatcat ggttgacgac gccattgtga taaaagatga ctatttcagt
     5041 ctgcccatca cgaggacaga cagcagcaaa gcgccgctcc actttcccat ccctgccgtc
     5101 cgatatgttg ttaaagaggt ctctctggtg tggcatcttt atggaggcaa ggactttgca
     5161 acagctcctc caacttctcc agctaagagt tacattagtc cccacagctc accgtctcaa
     5221 acacctacaa ggcacgggcg ccacacagtc tgtgggggca aaggaaggaa ccatgacttc
     5281 ttgatggaaa tacagttaag caaggtgaag tttcagcatg aggtctaccc tccgtgtaag
     5341 cctgagtgtg agtccagcct cttagaacac ccagtctcca ggcaggtctt catcgtgcag
     5401 gaccttgaaa ttcgagatcg gctggcaaca tcacagatga ataagttttt atacctgtat
     5461 tgcagcaaag acatgcctcg taaagcccat tccaacatgc tgacaattaa agcgttgcat
     5521 gtacgtccgg agtctggcag gtcaccacag gagtgctgct tgagagtgtc cctgatgcct
     5581 cttcgcctca atattgacca ggacgccttg ttcttcctca aggatttctt cacaagtctt
     5641 tctacagaag tggagcttct actgactcca gatccagaag ttacaaagtc tcctggagct
     5701 gatgtcacct gcagtttgcc aaggcatttg agtacctcaa aggagccaaa tctagtcgtt
     5761 tcttttcctg ggccaaaaca agcttccccg aaccatcgtg ccaattcagc ggagggtggt
     5821 aatggactgg aggaggacgt ctctgctgag gaaacttcat ttagtgacca gcctgtgttt
     5881 tttagagaat ttagattcac ggcagaagtt cccatccggc ttgactacca cggcaagcac
     5941 gtgtcgatgg atcagggtac attggctggg attttgattg gcctggccca gttgaactgt
     6001 tcggagctaa agctgaaaag gcttttctat cggcatggtt tgctaggtat tgacaaattg
     6061 ttctcatatg caatctcgga atggctcagt gacattaaga agaaccagct accaggaatc
     6121 ctgggaggtg ttggccctat gcattcacta gttcaattag tgcaaggcct gaaggacttg
     6181 gtatggctgc ccattgagca ataccggaag gatggccgta tcgtcagagg cttccagagg
     6241 ggcgctgctt cctttggtac ctcaactgca atggctgccc tggaactcac aaacagaatg
     6301 gtccaaacca tacaggcagc cgcagagact gcatatgaca tggtgtctcc gagtaccctt
     6361 tccattgagc ccaagaaggc aaagagattt cctcatcacc ggttagccca ccagccagta
     6421 gacctgaggg aaggcgtggc caaggcctac agcgttgtaa aagaggggat cacagacaca
     6481 gctcagacca tctatgaaac ggcggctcgg gaacacgaga gcagaggggt cactggtgct
     6541 gtgggtgaag tcctgcggca gatcccaccg gcagtggtca gacccctgat tgtagccacc
     6601 gaggcgacat caaatgtgtt aggtggcatg agaaaccaaa ttagaccaga cgttcggcag
     6661 gacgagtcgc agaaatggcg ccatggggag gactgatccc acagtgtgac tgattgcact
     6721 ccacactgtg tggagctgag ggcaggggcc tagtggcagc ttcctaggaa actagttcaa
     6781 ttcatgtgcc catctcagga acaaaagcag ttcttagtaa aataatttaa tatcaaaaca
     6841 acacacagcc aaaaacttgt gacattttag ggcctggcac ttgcctttca gagtggctgg
     6901 tgtcagtcac tagagatttg ctgccctgtg gaatgcttgc tttcattaaa gtgactctaa
     6961 ctgtacttgt tactgacaag agctcattgg gaatgagttt gtaaacagtg ttgagtgctt
     7021 aaagaaaggg gagcactcct gaggcactgg ggagcactct tcatagttct gaggagttga
     7081 tttttcagct cacagtgaca gaagccacag ggaaagtgaa gcagctgggg ctccagtgtc
     7141 tgtcaggtag cgaaggcctc gcctccctca ggcaacatgt gctgttctgc actttatctt
     7201 ctgtgagcgt gcgtttgtgt ctgtgtgtct gtgtctgtgt gtgtgtgtgt gcatctgtaa
     7261 tatgatgcaa ggtatgctgt gttctctgtg ttatttacaa ggttatataa atacgatgtg
     7321 aagtgaagat gtctcagagt ttttggtaaa ggaaggtaac ctagtgtaag tttctgtatc
     7381 ctaaatgcaa gtgagaatgt gagctctgtg gtgggctggg gcccgcgcat tgcttatgtg
     7441 gccactgtta aggacttagt gcagcccgtt agtgtcaagg gcattggaag tgggctttat
     7501 tcttagaaag atacataaaa atactcccaa gtatgttcta gacaactaat tcaaagtacc
     7561 atttttactt ggttaataat gtacattttg ataacttgtt gggaatgaat aaagtatttt
     7621 tatttaaagg taagattgtt gtatacgtcc atgaacattt gtttctctga aaagcatatt
     7681 tgttgatgca gtgctctgat tgaccaaagg acatgtggag atacctcgga gctgattgtc
     7741 actgtcactc attaggagga ggagtgtgtg atttgtgcct agagagtagc ccagcagaat
     7801 ggacctgggg ctttgcagcg ctgcatgttc ttactcttgg tttgtagacg ttggtggctc
     7861 ttggggatgc tggacaccgc agcagcattt ggtttgtgcg tgagaaagga agtcagtttc
     7921 accctctaag aactctgaac aaggaaccag gtcaaccttg actcacagcc acagccacag
     7981 ccccagcccc aacctctaga gctggttcaa aaaacaaaaa caaaacaaaa ttaaaaaaaa
     8041 aaaaaacaaa acaaaaccca gtcttgtaga catttgcatt cgctcgattt ccttttgttg
     8101 ccaggaaacg tcaaaagcta ccttggagtg gccactggtg gacctcatgg aactgctggc
     8161 ccttcgtcct tgttaggtgg agcccatgtc tgttatggct ctgaggagac actgcagtta
     8221 gtagtagcat ttgttgccat ggctggctgg cctgtttctg cccctctaat ggagcaggca
     8281 atgtgtgaca gctgttgaat ttggccaggc tttaccctgc ccctctctcc tccttggttc
     8341 catttaaggt cagtgtgcac gggagtaggg attagtgacc cctttgcctg gagcagcaca
     8401 caattcttcc agctagttaa attgatgaag ccattataaa aaggtgacct ctcctgcttc
     8461 actcttgcca gagctgctga tttggccccc aggtctttgt gcactgttga ggccctgtct
     8521 gtatttgaat gcttctaagt tacatatctg ctgtggtttc ttttaaaagg tgtctgctca
     8581 gactttggtc tcgtgatgtc atacagtgtg ttggcagtga gtgtccttgg gttgccttgt
     8641 ctgcagtcac caagcaaatg acttcacttg gccaagacac cttgtctcac tcagccccag
     8701 ggtcccctct gtaagtgaag aggtttcttg ggacaaggct tgtgagaatt tctgagcaat
     8761 taggtcacag tgacatgtac acaaaaagtg cccagatcct ccataccagg ctggtgggca
     8821 ccatcacatg gacactggct atgccatacc atggcagctg tgggatactc caggtctctg
     8881 ctctcagagt gacaccttca gggtctggca ccatgctgca tggttgaatc gggttgatag
     8941 ttctgactgg agcaggctgt acatacagag cactccccac agaagtcaag ggagttggct
     9001 tatttatgat cactgcgatg ttcccaccct gactccatca ccaatggcaa cagagaccac
     9061 agcgatggga ctgacttgga acctctgttt tttttttttt ttttttcttc ttgtttagtc
     9121 tgagcaggca tagatagaca tcatagcagt aggctttcat tttaatggac tgtttctctg
     9181 taccagtctg cctcacctct gcctgtattg aatacggtcc ctcagatccc aggcttctgg
     9241 ggacagtggg aagtgttcct tccctgcctc ccttcaaacg ccattgggaa tgtagaggtt
     9301 aaagtccttt ggaaggactg agtaaagaca gcaggatgct cctttctgca gcaggacggg
     9361 ccacttgtat caaagtaacc aaatgcacgt ttgtactgaa aaggctgaaa agagaggtga
     9421 tttgtatagc atagtgtgtc gaaatgaagc tttttttttt tttttttaaa tcgggaaatt
     9481 ttattttagt gtacaggaag gaccagtcac tattcttgta agaacactag tatgtcactt
     9541 gccagtcttg gtgtggacat tttcagggtt gtgctgggca cacttaacct ttgagagatt
     9601 ccatgggcac agttgcaagt cagcctgcat ggctcggaac tggtctccat ttgagacaga
     9661 aaaggcatcc tcatgagctg ccacgatagg cttctttgtg ggggaaatcg ttgagtctta
     9721 cttagcattt cacattttga atctcactag ttcctgtaga tgtagggctc agaggcccgt
     9781 gtcagccttc tctggccaac actggggttg ggcagccatt cacttaagtc cgcatcagag
     9841 aaaaactgcc tgtgctccag ttccggggtg agcatcttgt cggctgcccc ctctcggggc
     9901 tccccgccct tcacacatct tactcctgtc tcactgcact ctggttggaa ttgtctagct
     9961 gtgtttgtgt agctgctggg cgcactgggc tgctcacttg ttcgtggagt ttttgggttc
    10021 ccacgtaagt ttttctgtga gtcatcctag tctctctgct aagtgtcccg gctttcctaa
    10081 gtatggccac tctggatgta aataagaata ctcctctgta caagtatttt tgtgaaaaat
    10141 gtaacttgtt agtgtaacta tttaaaatat gatgacgtta agaatacttg tgaaaaaatt
    10201 aaaatattac ctctccgttt ttgctttaaa
//
