LOCUS       NM_001081304            7463 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus activating transcription factor 6 (Atf6), mRNA.
ACCESSION   NM_001081304 XM_888686
VERSION     NM_001081304.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7463)
  AUTHORS   Lee,E.J., Kim,K., Diaz-Aguilar,M.S., Min,H., Chavez,E.,
            Steinbergs,K.J., Safarta,L.A., Zhang,G., Ryan,A.F. and Lin,J.H.
  TITLE     Mutations in unfolded protein response regulator ATF6 cause hearing
            and vision loss syndrome
  JOURNAL   J Clin Invest (2024) In press
   PUBMED   39570676
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 7463)
  AUTHORS   Xu,L., Tan,C., Barr,J., Talaba,N., Verheyden,J., Chin,J.S.,
            Gaboyan,S., Kasaraneni,N., Elgamal,R.M., Gaulton,K.J., Lin,G.,
            Afshar,K., Golts,E., Meier,A., Crotty Alexander,L.E., Borok,Z.,
            Shen,Y., Chung,W.K., McCulley,D.J. and Sun,X.
  TITLE     Context-dependent roles of mitochondrial LONP1 in orchestrating the
            balance between airway progenitor versus progeny cells
  JOURNAL   Cell Stem Cell 31 (10), 1465-1483 (2024)
   PUBMED   39181129
REFERENCE   3  (bases 1 to 7463)
  AUTHORS   Borisova,E., Newman,A.G., Couce Iglesias,M., Dannenberg,R.,
            Schaub,T., Qin,B., Rusanova,A., Brockmann,M., Koch,J., Daniels,M.,
            Turko,P., Jahn,O., Kaplan,D.R., Rosario,M., Iwawaki,T.,
            Spahn,C.M.T., Rosenmund,C., Meierhofer,D., Kraushar,M.L.,
            Tarabykin,V. and Ambrozkiewicz,M.C.
  TITLE     Protein translation rate determines neocortical neuron fate
  JOURNAL   Nat Commun 15 (1), 4879 (2024)
   PUBMED   38849354
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7463)
  AUTHORS   Vanhoutte,D., Schips,T.G., Minerath,R.A., Huo,J., Kavuri,N.S.S.,
            Prasad,V., Lin,S.C., Bround,M.J., Sargent,M.A., Adams,C.M. and
            Molkentin,J.D.
  TITLE     Thbs1 regulates skeletal muscle mass in a
            TGFbeta-Smad2/3-ATF4-dependent manner
  JOURNAL   Cell Rep 43 (5), 114149 (2024)
   PUBMED   38678560
REFERENCE   5  (bases 1 to 7463)
  AUTHORS   Hofmann,C., Aghajani,M., Alcock,C.D., Blackwood,E.A., Sandmann,C.,
            Herzog,N., Gross,J., Plate,L., Wiseman,R.L., Kaufman,R.J.,
            Katus,H.A., Jakobi,T., Volkers,M., Glembotski,C.C. and Doroudgar,S.
  TITLE     ATF6 protects against protein misfolding during cardiac hypertrophy
  JOURNAL   J Mol Cell Cardiol 189, 12-24 (2024)
   PUBMED   38401179
  REMARK    GeneRIF: ATF6 protects against protein misfolding during cardiac
            hypertrophy.
REFERENCE   6  (bases 1 to 7463)
  AUTHORS   Yamamoto,K., Yoshida,H., Kokame,K., Kaufman,R.J. and Mori,K.
  TITLE     Differential contributions of ATF6 and XBP1 to the activation of
            endoplasmic reticulum stress-responsive cis-acting elements ERSE,
            UPRE and ERSE-II
  JOURNAL   J Biochem 136 (3), 343-350 (2004)
   PUBMED   15598891
  REMARK    GeneRIF: ATF6 and XBP1 have roles in activation of endoplasmic
            reticulum stress-responsive cis-acting elements
REFERENCE   7  (bases 1 to 7463)
  AUTHORS   Bilger,A., Bennett,L.M., Carabeo,R.A., Chiaverotti,T.A., Dvorak,C.,
            Liss,K.M., Schadewald,S.A., Pitot,H.C. and Drinkwater,N.R.
  TITLE     A potent modifier of liver cancer risk on distal mouse chromosome
            1: linkage analysis and characterization of congenic lines
  JOURNAL   Genetics 167 (2), 859-866 (2004)
   PUBMED   15238534
REFERENCE   8  (bases 1 to 7463)
  AUTHORS   Lee,A.H., Iwakoshi,N.N. and Glimcher,L.H.
  TITLE     XBP-1 regulates a subset of endoplasmic reticulum resident
            chaperone genes in the unfolded protein response
  JOURNAL   Mol Cell Biol 23 (21), 7448-7459 (2003)
   PUBMED   14559994
REFERENCE   9  (bases 1 to 7463)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 7463)
  AUTHORS   Eddleston,J., Murdoch,J.N., Copp,A.J. and Stanier,P.
  TITLE     Physical and transcriptional map of a 3-Mb region of mouse
            chromosome 1 containing the gene for the neural tube defect mutant
            loop-tail (Lp)
  JOURNAL   Genomics 56 (2), 149-159 (1999)
   PUBMED   10051400
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC113490.10 and AC125021.12.
            
            On Feb 6, 2007 this sequence version replaced XM_888686.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036335.1, AK036106.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               AC113490.10        53868-53989
            123-199             AC113490.10        66450-66526
            200-287             AC113490.10        68647-68734
            288-388             AC113490.10        72422-72522
            389-515             AC113490.10        79827-79953
            516-719             AC113490.10        80755-80958
            720-940             AC113490.10        86599-86819
            941-1126            AC113490.10        102207-102392
            1127-1218           AC113490.10        106125-106216
            1219-1350           AC113490.10        121894-122025
            1351-1464           AC113490.10        126869-126982
            1465-1564           AC113490.10        127583-127682
            1565-1632           AC113490.10        132964-133031
            1633-1747           AC113490.10        134179-134293
            1748-1832           AC113490.10        174449-174533
            1833-7463           AC125021.12        155595-161225       c
FEATURES             Location/Qualifiers
     source          1..7463
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 76.96 cM"
     gene            1..7463
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /note="activating transcription factor 6"
                     /db_xref="GeneID:226641"
                     /db_xref="MGI:MGI:1926157"
     exon            1..122
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            123..199
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            200..287
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            288..388
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            389..515
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            516..719
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            720..940
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1126
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1218
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1350
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1464
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..1564
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1632
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1747
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1748..1832
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..7463
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7224..7229
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /note="hexamer: AATAAA"
     polyA_site      7243
                     /gene="Atf6"
                     /gene_synonym="9130025P16Rik; 9630036G24; Atf6alpha;
                     ESTM49"
                     /note="major polyA site"
ORIGIN      
        1 gttactcacc catccgagtt gtgagggaga ggtgtctgtt tcggggaagc cggcttgtgt
       61 tgccggcgcc atggagtcgc cttttagtcc ggttcttcct catggaccag atgaagactg
      121 ggagtcgacg ttgtttgctg aacttggcta tttcacagac actgatgatg tgcactttga
      181 tgcagcacat gaggcttatg aaaataattt tgatcatctt aattttgatt tggatttgat
      241 gccttgggag tcagacctat ggagccccgg cagccacttc tgctcagaca tgaaggcaga
      301 gccccagcct ctttctccgg cttcctccag ttgctccatc tcctctcctc ggtccacaga
      361 ctcgtgttct tcaactcagc acgttcctga ggagttggat ttgttgtcta gttctcagtc
      421 ccccctttcc ttatatggcg acagctgtaa tagcccctcc tctgtagagc cactgaagga
      481 agagaagcct gtcactggtc ctggaaacaa aacagaacat ggactgactc caaagaaaaa
      541 aattcagatg agttcaaaac cttcagttca gcccaagcct ttattacttc cagcagcgcc
      601 caagactcaa accaatgcca gtgtcccagc aaaagccatc atcattcaga cactaccagc
      661 ccttatgcca ctggcaaagc agcagtcgat tatcagcata cagcctgcgc ccaccaaagg
      721 ccagactgtt ttgctctctc agccgactgt ggttcaactt cagagccctg cggttctgtc
      781 gtctgctcag ccggttcttg cagtcactgg gggagccgca cagctaccta accatgtggt
      841 gaatgtgctg ccagcccctg tggtgagcag cccggtgaat ggaaaacttt ccgtgactaa
      901 acctgttcta caaagtgcca ccagaagtat gggttcggat atcgctgtgc tgaggagaca
      961 gcagcggatg ataaagaacc gagagtctgc ttgtcagtcg cgcaagaaga agaaagagta
     1021 tatgctagga ctggaggcca ggctcaaggc tgccctctca gagaatgagc agctgaagaa
     1081 ggagaatggc tccctgaagc gacagctgga cgaggtggtg tcagagaacc agaggctcaa
     1141 agtcccaagt ccaaagcgaa gagctgtctg tgtgatgata gtattagcat ttataatgct
     1201 gaactatggg cccatgagca tgctggagca agaatcccga agagtgaaac ctagtgtgag
     1261 ccctgccaat cagaggaggc atctcttgga attttcagca aaagaagtta aagacacatc
     1321 agatggtgac aaccagaaag acagttacag ctatgatcac tctgtgtcca atgacaaagc
     1381 tttaatggtg ctaagtgaag agccattgct ttatatgcct ccacctccat gtcaacccct
     1441 gattaacaca acagagtctc tcaggttgaa ccatgaactt cgaggctggg ttcatagaca
     1501 tgaagtggaa aggaccaaat ctagaagaat gacaaatagc caacagaaag cccgcattct
     1561 ccagggtgct ctggaacagg gctctaattc tcagctgatg gctgtccagt acacagaaac
     1621 cactagcatc agtaggaatt ctgggagtga gctgcaagtg tattacgcct cccctggaag
     1681 ttaccaaggc ttctttgacg ccatccgcag gaggggagat acgttttacg ttgtctcatt
     1741 tcgaagggat catctgctat taccagctac cacccacaac aagaccacaa gaccaaaaat
     1801 gtcaattgta ttaccagcaa taaacataaa tgataatgtg atcaatgggc aggactatga
     1861 agtaatgatg cagattgact gtcaggtgat ggacaccagg atcctccaca tcaaaagctc
     1921 ctcggttccc ccttatctcc gggatcatca gcggaaccaa accagcacct tctttggttc
     1981 ccctccaaca accacagaga cgacccatgt ggtcagcacc atccctgagt cgttgcagta
     2041 gtgcccgagc tgcgctggac agcagagact gaagagctgg tgaagatgct gctctctgcc
     2101 tcttcggcaa gcagagactt gccttgtacg caactccagg ggaagaggaa gagagaacag
     2161 gaagtgcgct gcttgtcacc gtccacccag tggggtggaa catgctagcg agcaattctc
     2221 tggtggcagt gcagccctgt gggcagtgtc gcctggtgtt ggttctgctg tgtcatcttt
     2281 agtgcttttc tcaatgtgtg tttggttctc agttatcttc cttcaggtca gacccacttc
     2341 ctcttctgtc cactgcactt cctggtgcag taaagagatt tgtatttaaa gctttagaac
     2401 acatgctcat gtggtttcca ccaattggct ttctctctcc tttggttcaa atccattctg
     2461 aatgttatac ttgagaaaac acatttcaaa aaaccgagca gccaaaaaca tcccacaaag
     2521 agtcaaaaca gtttagagtt tgggtaaagg gattatctcc agttggtaag agtttatttt
     2581 tacttgtgat ttgtggttca gccctggaca aataactgtt gtgggggtca cagagtgagc
     2641 cacacactgg agacaaggga agggaaggcc agtggtggaa tgtaagggga agtgactcca
     2701 ttttcatatg tatttaaaca cagagttcct gtggcctcgg taagctcaga gctatagcca
     2761 ccctcagtgt tggaactcgg ctaatcagca gagatcttca aagatctcag ggcacatgct
     2821 tgcctctcat tgtggaccct cagcccagag catactcctg tgaaaccaga ctcagcaaag
     2881 ggacttggag gtcactaggc ttaagcaaga ctagagagtt tcccttaagg accaacagtg
     2941 cacagagcaa gcatggcttc ccagagaagc tgcagcacag tatggtgaag ttctcagttt
     3001 ttccagtgga aagatgataa aggaattaag ctctctttgt tgttgctatg gctgtgaaca
     3061 tggctttaat cctagcacca tttggaagga aaggcaggct ttgtttgata tcagcctggc
     3121 ctacatttca aattccagga caggacagct aaagctatat aaagaaccca cctcaaaaaa
     3181 tagatgaatg aataaatgag taaataaaca aatacaaaca aaaagcaaag ttatgttcac
     3241 atatatttta ttgtattttg cctgcttcct tcaccatagc aagcagccac atttctattg
     3301 cactgtacat tgtacgttac aagttcacag aaatggatgc caggactcat gtcagtcatg
     3361 tgctgcctcc cttcccagga tttcagcagg ttctcataga ctcttcccag ctggcttgcc
     3421 attgtcaggt ggtcccattc cagtaagcac aatggcggct aagtcctctt ctctctacaa
     3481 ggagtgacac acagtcaggt catcttttgc ctgtggcccc attatgcctg gcactgttca
     3541 ccaacaactg ttccctggac agcactgctg ccatctaagc taaggtgaga tgttttcagg
     3601 gcagggccat tcttgctgaa ttcagtgccg cagtccatcc tgattggctc tcgggtgatt
     3661 ttcagacaag acctgtttgt cccgggggct ggtcctctaa tgggtgccaa ggagaagata
     3721 ccaaatacat ggagtacctt taggagtagc catttgtggg ggaggtgggc taccctgtgg
     3781 ccatgtcctt cctgcctgtg aagcagctca acacgaggat gtgactgtgg ctgtggacag
     3841 aggcagcaca cgcattcctg atgctgatct gctgagacac gaatagaatc tgcagtgact
     3901 ccagtgtacc agtgcctcag atcaaagacc tcaatagtgt cacgtttgct aaggctgatg
     3961 cctctcctac aggtaacagt ggggatgacc gttggaaggc acagccaaag agcagacaga
     4021 agttaaggtg gccacagcac aggtcaggga tccaaggagc tggggaggac tgctcaaaac
     4081 tagtctggaa gcttgccttc tctgctcctg ctgaccatca ggtcctgtca ttaccactct
     4141 caggtccgtc ttatgagatg aggaatgggg ccctcctcag gggagagttt cagaaatgag
     4201 ggaaaggcaa ttatagatag aaagaagtat cctgccattt aaattgctga aagagctaga
     4261 atccctgggc tcggtagttt gtatcttaat gtttgtgcgc tagcacaggc ccattggaga
     4321 ggaaaagctg ttgtcctggg agcaaagtaa gcagccattc aggtctcatt ttttattttg
     4381 gtatgcttgc ccttgggtgt ttatagtccg gaactgtagg agctatgtat gtacataata
     4441 tatatatttt ttaatttatt aagttttaaa atgtgatttt tcaagattat gaaaaaatta
     4501 aataaatttg agctagagaa atggctcagt ggttaacttc gcttactgct cttccagagg
     4561 acccaggttc agttcccagc tttaagccat ctctaactcc attggggaca ggctagggga
     4621 tgggatcctc tacctttttc aggcctctgc agacaccaga cacacataat ggtgcacata
     4681 catgtgttca ggcaaaacgc taatatacat aaaaaataaa aacaaataaa tctggttttt
     4741 caatcagata aattcccaga ggaagtcact ccacctgtta ctagataatt ttgtgccctg
     4801 ggctgatggt actgtgatgt tgggaagtgt tgctagaggc tggcagtgtg gtctttcctg
     4861 tgtttgcaag ccccccactt ttaaattcag tgggagtaac tgcatgttcc ctcctgttaa
     4921 cagaacagct tctctctgca gttagctcat aaaacagctt ccttagaata gaatggaaac
     4981 ccactttcaa gttaggaggt gatgagaacg gatgcttgag agatgaatgt cagcagcaca
     5041 aagctgtccc ctttgccttt ctttctcatt agcaagaagt agaccctggg ctggccagat
     5101 ggctcaactg ctgagagctc ttgctgcatc tccaggagac ccaagttcca ttcctaacac
     5161 ccatgacaca gcccataacc cctaactcca gttccaggag atctaatgcc ctcttctagt
     5221 ctcccttggc atctgtgcac acatggcatt cactaacaca gttacacata aataataata
     5281 ttaatcgtga agcagacaag gaagtactca aaaagttaca taatgtgcgt cattcctgaa
     5341 ttttcccaat aactgtcact tgaaaacaga gggaactgac tttctctcgt atgtttaaag
     5401 tgactgtcgt ggttcaatct tgttggccca aatctccatc ctaggcaaat attccccagt
     5461 cgttacagct gcccaatgct gttagtcatg gctgccataa ctagaacatt taactcaaga
     5521 caactcccac agttccactg tgagactgta agactgggaa tttatctaat taaaaagtca
     5581 gtcttgctgt tttactatga aacttgacag aaatgtacca cagcaacaaa actaggaatc
     5641 acggttgact tcctcccaca tcaaaaactt ccagtccgac ttctgcttta atagcatgtt
     5701 agaagctctt gcatttcctt aacctagaga gccagcgttc ctatgcagtg gctccccatt
     5761 ctggtctcat ggaggtgccc ccatcaccac aacacccctc ccccgtgata gccttctttc
     5821 cacctcagcc tgggagcatt gacctcatcc ttcagcaggt acatacacct caacttccac
     5881 atgtgacctg tagctctgtc ataagaatca acttcccaag ctctccgcat agtcccagac
     5941 ttgagagtag cttattgcca ccggcaaact cgtagtcctt acccacctgt tctttggtca
     6001 gttatggggc attttaattt acataagtaa tgattttttt tttttgctgc taatatgaac
     6061 accagttata tttttaacca aaagaaaaaa agtaaggcct agaaggaaga taatggattg
     6121 aggacattgt cattcccacc ctgatagcac ttggaaagag acatttcctc cctggtgccc
     6181 actacaggaa ttgtgggtga tttttaagta actactggac tgcctaggaa gatattccca
     6241 gagtccgaaa ggaactatgc acatagagaa aatacagttt tctcctacct aaggaaacta
     6301 ttagtattct attagcttat atttttaata actaagctta aaacatagtt tattttggat
     6361 attactagaa cttgcagcaa ttctaatatc tgtcaggtac tcatagaatc tatggggaaa
     6421 aaaaagataa gactgtgtga ttaggaaact ttgtgagtca tggcatggcc agccagtgtc
     6481 acaaagcaac cctgtgcttg gctagcttta agcattacag acttagtaca tgaaaagact
     6541 taattatatt gggttcagga actaaagagt caatgagtca tctgtggagg tcaacaaata
     6601 acacactggt gggctttttg tcctccgtca agctggtgac tatagtgaaa tgaagcagga
     6661 agtgtagcat attccccagg atgctagttc cagactgaac cagcagactg aattcacagc
     6721 acgtgtgtgt caattgaact agcctagttc attatcacct ctactttctg ggcagttgcc
     6781 aggatgcagg agatgaagaa agctacaaag cactgctctc tttgagattc taggttttct
     6841 tttcttctca tcatggtaat gaggggcagt gaagccagag gtttaaatga gcatagaccc
     6901 atggtggatg gggtatgtag cttagatgga agactgcttg cttagagtgc ccgaagccat
     6961 ggcttccttc accacataaa ctaggacggt ggagtgtgct tagaatccta gcatttggga
     7021 ggtggaagtg ggaagatcgg gagttaaggg tcaaccaggg atacgtggga ccctgtctta
     7081 ccatgtgtgg aagaaatgca ggaaaaatgt attgttctct ccctgaataa ttatgtccgt
     7141 ttacaataaa taatggtggc agactatttc atattttcaa acaagtcttt ataatgcaat
     7201 acctgttctt cctctgaaat ccaaataaag acttttaaaa ctttgttgtc tgtctgtaca
     7261 aagacaaaaa caaatgaatc ttcaatgtta agtggttagt aatgggaatg gaagcctaaa
     7321 gaggacctgt ggcttgtggg tgtttagata aaacaccgag cttgtttctc tgtcctccca
     7381 cgatggacca agtagaaatt tgctttatgg aatccagaca tgtgtactac agtcacatca
     7441 aggaataaaa tcctctaaaa ccc
//
