LOCUS       NM_001410370            2535 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus activating transcription factor 1 (Atf1), transcript
            variant 3, mRNA.
ACCESSION   NM_001410370 XM_006520352
VERSION     NM_001410370.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Liu,L.L., Xiao,Y.S., Huang,W.M., Liu,S., Huang,L.X., Zhong,J.H.,
            Jia,P. and Liu,W.Y.
  TITLE     ATF1/miR-214-5p/ITGA7 axis promotes osteoclastogenesis to alter
            OVX-induced bone absorption
  JOURNAL   Mol Med 28 (1), 56 (2022)
   PUBMED   35568813
  REMARK    GeneRIF: ATF1/miR-214-5p/ITGA7 axis promotes osteoclastogenesis to
            alter OVX-induced bone absorption.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  AUTHORS   Tabara,M., Shiraishi,K., Takii,R., Fujimoto,M., Nakai,A. and
            Matsuyama,H.
  TITLE     Testicular localization of activating transcription factor 1 and
            its potential function during spermatogenesisdagger
  JOURNAL   Biol Reprod 105 (4), 976-986 (2021)
   PUBMED   34007999
  REMARK    GeneRIF: Testicular localization of activating transcription factor
            1 and its potential function during spermatogenesisdagger.
REFERENCE   3  (bases 1 to 2535)
  AUTHORS   Seneviratne,A., Han,Y., Wong,E., Walter,E.R.H., Jiang,L., Cave,L.,
            Long,N.J., Carling,D., Mason,J.C., Haskard,D.O. and Boyle,J.J.
  TITLE     Hematoma Resolution In Vivo Is Directed by Activating Transcription
            Factor 1
  JOURNAL   Circ Res 127 (7), 928-944 (2020)
   PUBMED   32611235
  REMARK    GeneRIF: Hematoma Resolution In Vivo Is Directed by Activating
            Transcription Factor 1.
REFERENCE   4  (bases 1 to 2535)
  AUTHORS   Williams,M.A., Biguetti,C., Romero-Bustillos,M., Maheshwari,K.,
            Dinckan,N., Cavalla,F., Liu,X., Silva,R., Akyalcin,S.,
            Uyguner,Z.O., Vieira,A.R., Amendt,B.A., Fakhouri,W.D. and Letra,A.
  TITLE     Colorectal Cancer-Associated Genes Are Associated with Tooth
            Agenesis and May Have a Role in Tooth Development
  JOURNAL   Sci Rep 8 (1), 2979 (2018)
   PUBMED   29445242
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2535)
  AUTHORS   Shi,X., Zirbes,K.M., Rasmussen,T.L., Ferdous,A., Garry,M.G.,
            Koyano-Nakagawa,N. and Garry,D.J.
  TITLE     The transcription factor Mesp1 interacts with cAMP-responsive
            element binding protein 1 (Creb1) and coactivates Ets variant 2
            (Etv2) gene expression
  JOURNAL   J Biol Chem 290 (15), 9614-9625 (2015)
   PUBMED   25694434
REFERENCE   6  (bases 1 to 2535)
  AUTHORS   Herdegen,T. and Leah,J.D.
  TITLE     Inducible and constitutive transcription factors in the mammalian
            nervous system: control of gene expression by Jun, Fos and Krox,
            and CREB/ATF proteins
  JOURNAL   Brain Res Brain Res Rev 28 (3), 370-490 (1998)
   PUBMED   9858769
  REMARK    Review article
REFERENCE   7  (bases 1 to 2535)
  AUTHORS   Ishiguro,N., Brown,G.D. and Meruelo,D.
  TITLE     Activation transcription factor 1 involvement in the regulation of
            murine H-2Dd expression
  JOURNAL   J Biol Chem 272 (25), 15993-16001 (1997)
   PUBMED   9188502
REFERENCE   8  (bases 1 to 2535)
  AUTHORS   Ji,L., Mochon,E., Arcinas,M. and Boxer,L.M.
  TITLE     CREB proteins function as positive regulators of the translocated
            bcl-2 allele in t(14;18) lymphomas
  JOURNAL   J Biol Chem 271 (37), 22687-22691 (1996)
   PUBMED   8798441
REFERENCE   9  (bases 1 to 2535)
  AUTHORS   Hsueh,Y.P. and Lai,M.Z.
  TITLE     Overexpression of activation transcriptional factor 1 in lymphomas
            and in activated lymphocytes
  JOURNAL   J Immunol 154 (11), 5675-5683 (1995)
   PUBMED   7751619
REFERENCE   10 (bases 1 to 2535)
  AUTHORS   Lee,M.R., Chung,C.S., Liou,M.L., Wu,M., Li,W.F., Hsueh,Y.P. and
            Lai,M.Z.
  TITLE     Isolation and characterization of nuclear proteins that bind to T
            cell receptor V beta decamer motif
  JOURNAL   J Immunol 148 (6), 1906-1912 (1992)
   PUBMED   1531847
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124479.4.
            
            On Aug 6, 2022 this sequence version replaced XM_006520352.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422597.1395773.1,
                                           SRR13422601.837086.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-430               AC124479.4         113366-113795       c
            431-529             AC124479.4         109865-109963       c
            530-630             AC124479.4         97351-97451         c
            631-761             AC124479.4         90497-90627         c
            762-941             AC124479.4         88423-88602         c
            942-1101            AC124479.4         88183-88342         c
            1102-2535           AC124479.4         81448-82881         c
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 56.22 cM"
     gene            1..2535
                     /gene="Atf1"
                     /note="activating transcription factor 1"
                     /db_xref="GeneID:11908"
                     /db_xref="MGI:MGI:1298366"
     exon            1..430
                     /gene="Atf1"
                     /inference="alignment:Splign:2.1.0"
     exon            431..529
                     /gene="Atf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             437..1246
                     /gene="Atf1"
                     /note="TCR-ATF1; cAMP-dependent transcription factor
                     ATF-1"
                     /codon_start=1
                     /product="cyclic AMP-dependent transcription factor ATF-1"
                     /protein_id="NP_001397299.1"
                     /db_xref="GeneID:11908"
                     /db_xref="MGI:MGI:1298366"
                     /translation="MEDSHKSNTTETASQPGSTVAGPHVSQIVHQVSSLSESEESQDS
                     SDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGEGENPSISAITSMSVPAPIYQ
                     TSSGQYIAIAPNGALQLASPSTDGVQALQTLTMTNSSSTQQGTILQYAQTSDGQQILV
                     PSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLASQTTKTDDPQLRREIRL
                     MKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKSV"
     exon            530..630
                     /gene="Atf1"
                     /inference="alignment:Splign:2.1.0"
     exon            631..761
                     /gene="Atf1"
                     /inference="alignment:Splign:2.1.0"
     exon            762..941
                     /gene="Atf1"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1101
                     /gene="Atf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..2535
                     /gene="Atf1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2511..2516
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Atf1"
                     /note="hexamer: ATTAAA"
     polyA_site      2535
                     /gene="Atf1"
                     /note="major polyA site"
ORIGIN      
        1 agtcagtgct cttaactgtt gagccatttc tccagacctt caacatcttt ttcaaggaag
       61 gaagctaaga cgccttttcc tcactcacca gctgagaagt ctctgtactt gatatttatt
      121 gatatttact gttcactcgt gacagtctgc tggtcactga gcacacttta ctgcagacag
      181 gcactgcctt tagagagctt aaagctggga gaaacaggca ggctagtaaa catagctgtt
      241 aagtaattca gagataacga gccaggcaag acaaatgtat taaaatagga cctgatccag
      301 gcgtagtggc acaagccttt aaccccagct caggcggcag aggctctaaa gaccaaacca
      361 acctcctacc cctcacccag gaaggaaaga aaaccacagg acttggtaca gtaaggaatg
      421 gcagtaagag ttgattatgg aagattccca caagagtaac acgacagaga ctgcatctca
      481 gcctggttca accgttgcgg ggcctcacgt ttctcagata gtacatcagg tgtcatcgtt
      541 atcagaaagt gaggagtctc aggactcatc tgacagcata ggctcctcac agaaagctca
      601 cgggatcctg gcccggcgcc catcctacag gaaaattttg aaagacctct cttctgaaga
      661 tacacggggc agaaaagggg aaggagaaaa tcccagcatt tctgccatca cgtctatgtc
      721 tgttccagcc cccatctatc agacgagcag cggacagtac attgccattg ccccaaacgg
      781 agccttacag ttggccagtc caagcacgga tggagtgcag gcactgcaga cattaaccat
      841 gacaaattca agcagtactc agcaggggac gatcctccag tatgcacaga cctctgacgg
      901 acagcagata ctcgtcccga gcaaccaggt ggttgtacag actgcatcag gagatatgca
      961 gacctaccag atccgtacca cgccgtctgc cacgtctctc ccgcagaccg tggtgatgac
     1021 ttctcctgtg actcttgcat ctcagacaac aaagacagat gaccctcaac taagaagaga
     1081 aatacgactg atgaaaaaca gagaagctgc ccgagagtgc cgccggaaga agaaggagta
     1141 cgtgaagtgc ctggagaacc gtgttgctgt tctggaaaat caaaataaaa ctctaataga
     1201 ggagctaaag actttgaagg acctttattc tcataaaagt gtttgattct ttaaagagaa
     1261 agtatttttt gtggacttta aagcttaaaa attaggtgga tttcttttta gtggagttct
     1321 ataaattcaa aggtcaaaga agctactttg tattaggttt tcacaaacag acatgatgga
     1381 gggagaatgg agatgacctg caggaagcta ctgtctcaat tggaagctcc gaaaagatag
     1441 agtgctcaag gaatggactt tcagcagttt aaatagaaat aatggtcagc aacgaaaatg
     1501 gcaggcgacg ttagtgaagc agtccgttcc tgctacgtct gtatttctct gttccctaaa
     1561 acttgccttt gtgtgtgtgc gcgcgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     1621 gtgtgtgtgt gtgtgtgtgt gtgcgtgcgt gcctcatttc tgccaataaa tttacaaatg
     1681 taaaagcata aagcgttact aagtatgtaa attatgtggt ctgattgtgt cgtaatgtca
     1741 ggtatgttaa atgagttttt agcagttagt ttggttggac tcgattggtt tggagatctc
     1801 ctaaatggcg tggagacaca tcagcctgtg gtggaggtgg tttgtgactt tgctttgtca
     1861 gaatggaaag agaactgtct gcaagtttga cagtttaata gtttgttttt tgcttcctct
     1921 gataagggca agtacataat agattggttt tgtttttttt gttttttgat tctctaatcc
     1981 tgtgtgcagt tgaagatcat tctcttgcgc tttaacagaa tgaagtgttt acaaaggccc
     2041 tcaaatgttt taaataacct gaatatgcac accaaagctt tcctgagggg ttttataatc
     2101 atcttaccgt aaggtttgtc aggttctaaa acagttactg aggcaatctt acattgagac
     2161 tattgtgtaa tgtagcccat ggtaccttta taaaagaagt gactgccgat atatttttat
     2221 agtgaatctt tataaattct aatgttgagt ttttaatgat tattttaaat gtttatatag
     2281 tttgtttagc aaaaaaaatt ttgtatctca aagtatcatt tttatattat gagaagagta
     2341 aaattttcaa attggctgat aattgaattg tatgttttat ataaagtttt atctaaagtt
     2401 tcagctgtgg tcagtacacc agcatttaac ctctgtattc taatctgtgt tcacttggaa
     2461 actgcagaac tgttgtgtac ctacagagta tgtttcatat tgtctgtgaa attaaaaaac
     2521 atttgataag attaa
//
