LOCUS       NM_001357013            3115 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus aspartate beta-hydroxylase domain containing 2
            (Asphd2), transcript variant 4, mRNA.
ACCESSION   NM_001357013 XM_011249571
VERSION     NM_001357013.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3115)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC123848.4.
            
            On Oct 14, 2017 this sequence version replaced XM_011249571.2.
            
            Transcript Variant: This variant (4) differs in the 5' UTR compared
            to variant 1. All six variants encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.249104.1,
                                           SRR7974084.17636.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                AC123848.4         19998-20053
            57-271              AC123848.4         20772-20986
            272-395             AC123848.4         21188-21311
            396-1493            AC123848.4         22516-23613
            1494-1607           AC123848.4         27899-28012
            1608-3115           AC123848.4         28910-30417
FEATURES             Location/Qualifiers
     source          1..3115
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 54.7 cM"
     gene            1..3115
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /note="aspartate beta-hydroxylase domain containing 2"
                     /db_xref="GeneID:72898"
                     /db_xref="MGI:MGI:1920148"
     exon            1..56
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            57..271
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            272..395
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            396..1493
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             686..1717
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /codon_start=1
                     /product="aspartate beta-hydroxylase domain-containing
                     protein 2"
                     /protein_id="NP_001343942.1"
                     /db_xref="CCDS:CCDS19542.1"
                     /db_xref="GeneID:72898"
                     /db_xref="MGI:MGI:1920148"
                     /translation="MWLEWLVAWSWSLDGLRDCIATGIQSVRDCDGTAVITVACLLIL
                     FVWYCYHVGREQPRPHVSVNSLLQGVDANGLQNGSMYCQSPECARCTHHEGLNQKLYH
                     NLQEYAKRYSWSGMGRIHKGIREQGRYLSSQPSIQKPEVFFLPDLPTTPYFSRDAQKH
                     DVELLERNFQAILCEFETLYKAFSNCSLPQGWKVNSTPSGEWFTFDFVSQGVCVPRNC
                     RKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNG
                     CELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGSAEDGPRVVFMVDLWHPNVAAAERQA
                     LDFIFAPGR"
     exon            1494..1607
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1608..3115
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1993..1998
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /note="hexamer: AATAGA"
     polyA_site      2024
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /note="major polyA site"
     regulatory      3095..3100
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3115
                     /gene="Asphd2"
                     /gene_synonym="2900006N09Rik; 9230106G13Rik"
ORIGIN      
        1 gcggccgcgt ccctggggca gtggcgtcgc ccgggtcccc gcagccgccc gcgcagagcc
       61 ggctgatctt tgagatctga ggttcggggc tgcatgatgc ccgttcctga tgggaactga
      121 tctgtgaaga gagccagaag tgtgtgtgtc tacctattat cctgatgcca cacactctac
      181 caaaaccaga gtttgttctc ttgtcacaaa tcagctctgg acttgtgtgt ccctccctgg
      241 gcgaaggggc cgccagcctc ctggaactca agttggtggg aactcggttt cttgagtcag
      301 ttattaccac tgactggggc tcaggacatc cgaagaaacc tggctgatga aagcagtttt
      361 ggagttacag tttcctcaga gtctatgaac accaggtttg gacgtcatga aaaccctttc
      421 acggtgactg attgcatttg ctaatgggac ataaggcagc gccctccacc ccactgcggt
      481 gacttttcct agtgggccca gttggcaggc ctcactgttc atcaatggag cccttggcag
      541 gaaccgaggg acagtggcag ccatgcctcc ccctgccacc gcggctcctt ctgcctcctg
      601 ctaacctgca tgccgtgggt gccctggaga cgcccagagg actgaccatc tgagccagct
      661 tgcctcaagc acggagtccc tcaagatgtg gctggagtgg ttggtggcct ggagctggtc
      721 tctggatggc ctgagggact gcattgccac cggtatccag tcagtgcggg actgcgatgg
      781 cacagccgtc atcaccgtgg cctgcctgct catcctgttt gtgtggtact gttaccacgt
      841 gggccgcgag cagccccgcc cccacgtgtc tgtcaactcc ctcctgcagg gcgtggatgc
      901 caacgggctg cagaatgggt ccatgtactg ccagtcacca gagtgtgcgc gctgcacaca
      961 ccacgaaggc ctcaaccaga agctctacca caacctgcag gaatacgcca agcggtactc
     1021 atggtccggc atgggccgca ttcacaaggg catccgggag cagggccgct acctcagcag
     1081 ccagccctcc atccagaagc ccgaggtctt cttcctgcct gacctcccca ctacgcccta
     1141 cttctcccgg gatgcccaga agcacgatgt ggagctgttg gagcggaact tccaggcgat
     1201 cctctgcgag ttcgagactc tctacaaagc cttctctaac tgcagcctcc ctcaagggtg
     1261 gaaagtgaac agcaccccca gtggggagtg gttcaccttt gactttgtca gccagggcgt
     1321 ttgtgtcccc aggaactgca ggaagtgccc gcggacttac cgcttgctcg gcagcctccg
     1381 gacctgtatt gggaacaatg ttttcgggaa cgcctgcatc tcagtgctga gccctgggac
     1441 tgtgatcacg gagcactacg gacccacaaa catccgcatc cgatgccacc taggtttgaa
     1501 gactcccaat ggctgcgagc tggtggtggg gggcgagccc cagtgctggg cagaaggccg
     1561 atgcttactc tttgatgact cgttcctgca cactgcgttc catgaaggtt ccgctgagga
     1621 tggcccacgg gtggtcttca tggtagacct ctggcacccc aacgtggcag ctgctgaacg
     1681 tcaggccctg gatttcatct ttgctccggg acgatgagga cattgcctgg gctggagcca
     1741 ggctgagtgg atgggtggac tgtgggattg cccaccctga ctgtgccctg atccatgctg
     1801 gaagcatgaa tggcttcctg ccactgtggg gcgtctttcc tttggttact gggaacttcc
     1861 taggtttctt tccccttctg gctaattgct gggacttctg gcctactagt gtgtcccttt
     1921 ggctgtgacc agaggctctg tgcctctcct gtccgtgtca ctttgctacc tggtgtcctg
     1981 tccatgttct ggaatagagt aaccaaatga ctgttttgtc taaatgtaat catcctaaat
     2041 ttctgtagct gtctcaagag agagcaaaaa caaacaaaca aaaccaaaac aaagcaccac
     2101 agaccagaag ccattgagcc agacagcttg gcctctgatg ctggggttcc tcactgtccc
     2161 agagcaggaa acagcctgca gcctgcctgt acacctggtt ggtttcatta tgggcttacc
     2221 agacaccctc ggggtggttg tgtaagtcaa cgcccaggga atccatcatt attgctgata
     2281 gaccccaaaa tctatcagag ccctgctggt ggcgacctgg gccttttctt taaccacagc
     2341 ttcctccaga gctgaaggct agtgagggct ctcaggtcag ccacagaaca gggatccact
     2401 tagctcactg cctactgccg agcccggcct gacagacgct gccgctgtgg tttcgagtcc
     2461 acaagattgg caggaagcat gctgggctga acctctacca ccgaccatgt gaccgtagtg
     2521 cctgtccatc atgctttgca gtctgttacc taagggttga cattgattat atctgtgtgc
     2581 aaaccttcac acgctagact cagagacagc caagagttat ggccatgtct gtcaacccga
     2641 taaccggagc ccatgggtgt ctctgacacc agagacagct gactcttcag tcaccagaga
     2701 agacacacac agttcttttc ccaaagtgaa ggccaaccag aggccctggg tccagctgat
     2761 aggagagcgc agtcagccag gcactctcag ggatgcgctg ggagtggtgg ccccatgggc
     2821 atggtccaga gcaggacaga gtggacagct tttggtacaa gtttgatgtt aggtccaaat
     2881 gcaaaaccag tcacctttag aaggtaattt gatgatgtca gtccacaatg gggttagggt
     2941 ggggggaagc acccagaaca tttctctgct cagagttgag gatggaagca tcaggctttg
     3001 gagtttttgc actcggggtc tcagcagagt cccctgaagt gcatgatcca cacctatcct
     3061 gactgtcccc accacacacc aaggacaggg agtaaataaa gagctttgct gacaa
//
